-
1
-
-
65949104286
-
mTORC1 signaling governs hematopoietic stem cell quiescence
-
Gan B, DePinho RA. mTORC1 signaling governs hematopoietic stem cell quiescence. Cell Cycle. 2009;8(7):1003-6.
-
(2009)
Cell Cycle
, vol.8
, Issue.7
, pp. 1003-1006
-
-
Gan, B.1
DePinho, R.A.2
-
2
-
-
77952007543
-
Mammalian target of rapamycin (mTOR): Conducting the cellular signaling symphony
-
Foster KG, Fingar DC. Mammalian target of rapamycin (mTOR): conducting the cellular signaling symphony. J Biol Chem. 2010;285(19):14071-7.
-
(2010)
J Biol Chem
, vol.285
, Issue.19
, pp. 14071-14077
-
-
Foster, K.G.1
Fingar, D.C.2
-
3
-
-
3242892160
-
The multifaceted role of mTOR in cellular stress responses
-
Proud CG. The multifaceted role of mTOR in cellular stress responses. DNA Repair (Amst). 2004;3(8-9):927-34.
-
(2004)
DNA Repair (Amst)
, vol.3
, Issue.8-9
, pp. 927-934
-
-
Proud, C.G.1
-
4
-
-
33644769115
-
Mammalian target of rapamycin (mTOR) regulates both proliferation of megakaryocyte progenitors and late stages of megakaryocyte differentiation
-
Raslova H, Baccini V, Loussaief L, Comba B, Larghero J, Debili N, et al. Mammalian target of rapamycin (mTOR) regulates both proliferation of megakaryocyte progenitors and late stages of megakaryocyte differentiation. Blood. 2006;107(6):2303-10.
-
(2006)
Blood
, vol.107
, Issue.6
, pp. 2303-2310
-
-
Raslova, H.1
Baccini, V.2
Loussaief, L.3
Comba, B.4
Larghero, J.5
Debili, N.6
-
5
-
-
77958470125
-
Mammalian target of rapamycin controls dendritic cell development downstream of Flt3 ligand signaling
-
Sathaliyawala T, O'Gorman WE, Greter M, Bogunovic M, Konjufca V, Hou ZE, et al. Mammalian target of rapamycin controls dendritic cell development downstream of Flt3 ligand signaling. Immunity. 2010;33(4):597-606.
-
(2010)
Immunity
, vol.33
, Issue.4
, pp. 597-606
-
-
Sathaliyawala, T.1
O'Gorman, W.E.2
Greter, M.3
Bogunovic, M.4
Konjufca, V.5
Hou, Z.E.6
-
6
-
-
77954955537
-
The emerging role of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin signaling network in normal myelopoiesis and leukemogensis
-
Martelli AM, Evangelisti C, Chiarini F, Grimaldi C, Cappellini A, Ognibene A, et al. The emerging role of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin signaling network in normal myelopoiesis and leukemogensis. Biochim Biophys Acta. 2010;1803(9):991-1002.
-
(2010)
Biochim Biophys Acta
, vol.1803
, Issue.9
, pp. 991-1002
-
-
Martelli, A.M.1
Evangelisti, C.2
Chiarini, F.3
Grimaldi, C.4
Cappellini, A.5
Ognibene, A.6
-
7
-
-
33646351002
-
PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention
-
Zhang J, Grindley JC, Yin T, Jayasinghe S, He XC, Ross JT, et al. PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention. Nature. 2006;441(7092):518-22.
-
(2006)
Nature
, vol.441
, Issue.7092
, pp. 518-522
-
-
Zhang, J.1
Grindley, J.C.2
Yin, T.3
Jayasinghe, S.4
He, X.C.5
Ross, J.T.6
-
8
-
-
53349091768
-
TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species
-
Chen C, Liu Y, Liu R, Ikenoue T, Guan KL, Liu Y, et al. TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species. J Exp Med. 2008;205(10):2397-408.
-
(2008)
J Exp Med
, vol.205
, Issue.10
, pp. 2397-2408
-
-
Chen, C.1
Liu, Y.2
Liu, R.3
Ikenoue, T.4
Guan, K.L.5
Liu, Y.6
-
9
-
-
6344245674
-
Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development
-
Gangloff YG, Mueller M, Dann SG, Svoboda P, Sticker M, Spetz JF, et al. Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development. Mol Cell Biol. 2004;24(21):9508-16.
-
(2004)
Mol Cell Biol
, vol.24
, Issue.21
, pp. 9508-9516
-
-
Gangloff, Y.G.1
Mueller, M.2
Dann, S.G.3
Svoboda, P.4
Sticker, M.5
Spetz, J.F.6
-
10
-
-
66949173728
-
The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment
-
Delgoffe GM, Kole T P, Zheng Y, Zarek PE, Matthews KL, Xiao B, et al. The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment. Immunity. 2009;30(6):832-44.
-
(2009)
Immunity
, vol.30
, Issue.6
, pp. 832-844
-
-
Delgoffe, G.M.1
Kole, T.P.2
Zheng, Y.3
Zarek, P.E.4
Matthews, K.L.5
Xiao, B.6
-
11
-
-
74049088121
-
Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy
-
Risson V, Mazelin L, Roceri M, Sanchez H, Moncollin V, Corneloup C, et al. Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy. J Cell Biol. 2009;187(6):859-74.
-
(2009)
J Cell Biol
, vol.187
, Issue.6
, pp. 859-874
-
-
Risson, V.1
Mazelin, L.2
Roceri, M.3
Sanchez, H.4
Moncollin, V.5
Corneloup, C.6
-
12
-
-
33744505375
-
Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1
-
Um SH, D'Alessio D, Thomas G. Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1. Cell Metab. 2006;3(6):393-402.
-
(2006)
Cell Metab
, vol.3
, Issue.6
, pp. 393-402
-
-
Um, S.H.1
D'Alessio, D.2
Thomas, G.3
-
13
-
-
79953705050
-
Ex vivo rapamycin treatment of human cord blood CD34+ cells enhances their engraftment of NSG mice
-
Rohrabaugh SL, Campbell TB, Hangoc G, Broxmeyer HE. Ex vivo rapamycin treatment of human cord blood CD34+ cells enhances their engraftment of NSG mice. Blood Cell Mol Dis. 2011;46(4):318-20.
-
(2011)
Blood Cell Mol Dis
, vol.46
, Issue.4
, pp. 318-320
-
-
Rohrabaugh, S.L.1
Campbell, T.B.2
Hangoc, G.3
Broxmeyer, H.E.4
-
14
-
-
84866082606
-
mTOR complex 1 plays critical roles in hematopoiesis and Pten-loss-evoked leukemogenesis
-
Kalaitzidis D, Sykes SM, Wang Z, Punt N, Tang Y, Ragu C, et al. mTOR complex 1 plays critical roles in hematopoiesis and Pten-loss-evoked leukemogenesis. Cell Stem Cell. 2012;11(3):429-39.
-
(2012)
Cell Stem Cell
, vol.11
, Issue.3
, pp. 429-439
-
-
Kalaitzidis, D.1
Sykes, S.M.2
Wang, Z.3
Punt, N.4
Tang, Y.5
Ragu, C.6
-
15
-
-
84861833364
-
mTORC1 is essential for leukemia propagation but not stem cell self-renewal
-
Hoshii T, Tadokoro Y, Naka K, Ooshio T, Muraguchi T, Sugiyama N, et al. mTORC1 is essential for leukemia propagation but not stem cell self-renewal. J Clin Invest. 2012;122(6): 2114-29.
-
(2012)
J Clin Invest
, vol.122
, Issue.6
, pp. 2114-2129
-
-
Hoshii, T.1
Tadokoro, Y.2
Naka, K.3
Ooshio, T.4
Muraguchi, T.5
Sugiyama, N.6
-
16
-
-
84864818063
-
A critical role for rictor in T lymphopoiesis
-
Tang F, Wu Q, Ikenoue T, Guan KL, Liu Y, Zheng P. A critical role for rictor in T lymphopoiesis. J Immunol. 2012;189(4):1850-7.
-
(2012)
J Immunol
, vol.189
, Issue.4
, pp. 1850-1857
-
-
Tang, F.1
Wu, Q.2
Ikenoue, T.3
Guan, K.L.4
Liu, Y.5
Zheng, P.6
-
17
-
-
84861719535
-
Vital roles of mTOR complex 2 in Notch-driven thymocyte differentiation and leukemia
-
Lee K, Nam KT, Cho SH, Gudapati P, Hwang Y, Park DS, et al. Vital roles of mTOR complex 2 in Notch-driven thymocyte differentiation and leukemia. J Exp Med. 2012;209(4):713-28.
-
(2012)
J Exp Med
, vol.209
, Issue.4
, pp. 713-728
-
-
Lee, K.1
Nam, K.T.2
Cho, S.H.3
Gudapati, P.4
Hwang, Y.5
Park, D.S.6
-
18
-
-
84866064701
-
Temporal Changes in PTEN and mTORC2 Regulation of Hematopoietic Stem Cell Self-Renewal and Leukemia Suppression
-
Magee JA, Ikenoue T, Nakada D, Lee JY, Guan KL, Morrison SJ. Temporal Changes in PTEN and mTORC2 Regulation of Hematopoietic Stem Cell Self-Renewal and Leukemia Suppression. Cell Stem Cell. 2012;11(3):415-28.
-
(2012)
Cell Stem Cell
, vol.11
, Issue.3
, pp. 415-428
-
-
Magee, J.A.1
Ikenoue, T.2
Nakada, D.3
Lee, J.Y.4
Guan, K.L.5
Morrison, S.J.6
-
19
-
-
84885666003
-
mTOR regulates DNA damage response through NF-κB-mediated FANCD2 pathway in hematopoietic cells
-
Mar 29
-
Guo F, Li J, Du W, Zhang S, O'Connor M, Thomas G, Kozma S, et al. mTOR regulates DNA damage response through NF-κB-mediated FANCD2 pathway in hematopoietic cells. Leukemia. 2013 Mar 29.
-
(2013)
Leukemia
-
-
Guo, F.1
Li, J.2
Du, W.3
Zhang, S.4
O'Connor, M.5
Thomas, G.6
Kozma, S.7
-
20
-
-
59249097362
-
The TSC-mTOR pathway mediates translational activation of TOP mRNAs by insulin largely in a raptor-or rictor-independent manner
-
Patursky-Polischuk I, Stolovich-Rain M, Hausner-Hanochi M, Kasir J, Cybulski N, Avruch J, et al. The TSC-mTOR pathway mediates translational activation of TOP mRNAs by insulin largely in a raptor-or rictor-independent manner. Mol Cell Biol. 2009;29(3):640-9.
-
(2009)
Mol Cell Biol
, vol.29
, Issue.3
, pp. 640-649
-
-
Patursky-Polischuk, I.1
Stolovich-Rain, M.2
Hausner-Hanochi, M.3
Kasir, J.4
Cybulski, N.5
Avruch, J.6
|