FoxO3a regulates hematopoietic homeostasis through a negative feedback pathway in conditions of stress or aging

Blood

Volumn 112, Issue 12, 2008, Pages 4485-4493

  Miyamoto, Kana ^a,b   Miyamoto, Takeshi ^a,b,c,d   Kato, Reiko ^c   Yoshimura, Akihiko ^c   Motoyama, Noboru ^e   Suda, Toshio ^a,c  

^a Sakaguchi Laboratory of Developmental Biology   (Japan)

^b Department of Orthopedic Surgery ^*  (Japan)

^c KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^e NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1B; FLUOROURACIL; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; SPRED2; SPROUTY PROTEIN; TRANSCRIPTION FACTOR FKHRL1; UNCLASSIFIED DRUG; VASODILATOR STIMULATED PHOSPHOPROTEIN; FORKHEAD TRANSCRIPTION FACTOR; FOXO3 PROTEIN, MOUSE; ONCOPROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL AGING; CELL PROLIFERATION; CELL STRESS; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME REGULATION; FLOW CYTOMETRY; HEMATOPOIESIS; HEMATOPOIETIC CELL; HEMATOPOIETIC STEM CELL; HOMEOSTASIS; IMMUNOHISTOCHEMISTRY; MOUSE; NEGATIVE FEEDBACK; NEUTROPHILIA; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; STEM CELL; UPREGULATION; AGING; ANIMAL; BIOLOGICAL MODEL; C57BL MOUSE; CELL CULTURE; FEEDBACK SYSTEM; GENETICS; GRANULOCYTE; METABOLISM; MOUSE MUTANT; NEUTROPENIA; NEUTROPHIL; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGICAL STRESS; PHYSIOLOGY;

AGING; ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEEDBACK, BIOCHEMICAL; FORKHEAD TRANSCRIPTION FACTORS; GRANULOCYTES; HEMATOPOIESIS; HOMEOSTASIS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, BIOLOGICAL; NEUTROPENIA; NEUTROPHILS; ONCOGENE PROTEIN V-AKT; PHOSPHORYLATION; STRESS, PHYSIOLOGICAL;

EID: 58149398745     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2008-05-159848     Document Type: Article

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