-
1
-
-
84867167320
-
Platelet signaling
-
Stalker T.J., Newman D.K., Ma P., Wannemacher K.M., Brass L.F. Platelet signaling. Handb. Exp. Pharmacol. 2012, 210:59-85.
-
(2012)
Handb. Exp. Pharmacol.
, vol.210
, pp. 59-85
-
-
Stalker, T.J.1
Newman, D.K.2
Ma, P.3
Wannemacher, K.M.4
Brass, L.F.5
-
2
-
-
28444446286
-
Platelet G, protein-coupled receptors in hemostasis and thrombosis
-
Woulfe D.S. Platelet G, protein-coupled receptors in hemostasis and thrombosis. J. Thromb. Haemost. 2005, 3:2193-2200.
-
(2005)
J. Thromb. Haemost.
, vol.3
, pp. 2193-2200
-
-
Woulfe, D.S.1
-
3
-
-
0034927336
-
Regulation of phosphoinositide-specific phospholipase C
-
Rhee S.G. Regulation of phosphoinositide-specific phospholipase C. Annu. Rev. Biochem. 2001, 70:281-312.
-
(2001)
Annu. Rev. Biochem.
, vol.70
, pp. 281-312
-
-
Rhee, S.G.1
-
4
-
-
84880597666
-
Platelet receptors activated via multimerization: glycoprotein VI, GPIb-IX-V, and CLEC-2
-
Ozaki Y., Suzuki-Inoue K., Inoue O. Platelet receptors activated via multimerization: glycoprotein VI, GPIb-IX-V, and CLEC-2. J. Thromb. Haemost. 2013, 11:330-339.
-
(2013)
J. Thromb. Haemost.
, vol.11
, pp. 330-339
-
-
Ozaki, Y.1
Suzuki-Inoue, K.2
Inoue, O.3
-
5
-
-
26444535506
-
GPVI and integrin αIIbβ3 signaling in platelets
-
Watson S.P., Auger J.M., McCarty O.J.T., Pearche A.C. GPVI and integrin αIIbβ3 signaling in platelets. J. Thromb. Haemost. 2005, 4:1752-1762.
-
(2005)
J. Thromb. Haemost.
, vol.4
, pp. 1752-1762
-
-
Watson, S.P.1
Auger, J.M.2
McCarty, O.J.T.3
Pearche, A.C.4
-
6
-
-
67649470550
-
Integrin α2β1 induces phosphorylation-dependent and phosphorylation-independent activation of phospholipase Cγ2 in platelets: role of Src kinase and Rac GTPase
-
Guidetti G.F., Bernardi B., Consonni A., Rizzo P., Gruppi C., Balduini C., Torti M. Integrin α2β1 induces phosphorylation-dependent and phosphorylation-independent activation of phospholipase Cγ2 in platelets: role of Src kinase and Rac GTPase. J. Thromb. Haemost. 2009, 7:1200-1206.
-
(2009)
J. Thromb. Haemost.
, vol.7
, pp. 1200-1206
-
-
Guidetti, G.F.1
Bernardi, B.2
Consonni, A.3
Rizzo, P.4
Gruppi, C.5
Balduini, C.6
Torti, M.7
-
7
-
-
2342486055
-
Phosphoinositide 3-kinases and the regulation of platelet function
-
Jackson S.P., Yap C.L., Anderson K.E. Phosphoinositide 3-kinases and the regulation of platelet function. Biochem. Soc. Trans. 2004, 32:387-392.
-
(2004)
Biochem. Soc. Trans.
, vol.32
, pp. 387-392
-
-
Jackson, S.P.1
Yap, C.L.2
Anderson, K.E.3
-
8
-
-
0035464192
-
Resistance to thromboembolism in PI3Kγ-deficient mice
-
Hirsch E., Bosco O., Tropel P., Laffargue M., Calvez R., Altruda F., Wymann M., Montrucchio G. Resistance to thromboembolism in PI3Kγ-deficient mice. FASEB J. 2001, 15:2019-2021.
-
(2001)
FASEB J.
, vol.15
, pp. 2019-2021
-
-
Hirsch, E.1
Bosco, O.2
Tropel, P.3
Laffargue, M.4
Calvez, R.5
Altruda, F.6
Wymann, M.7
Montrucchio, G.8
-
9
-
-
70349251723
-
Genetic evidence for a predominant role of PI3Kβ catalytic activity in ITAM- and integrin-mediated signaling in platelets
-
Canobbio I., Stefanini L., Cipolla L., Ciraolo E., Gruppi C., Balduini C., Torti M. Genetic evidence for a predominant role of PI3Kβ catalytic activity in ITAM- and integrin-mediated signaling in platelets. Blood 2009, 114:2193-2196.
-
(2009)
Blood
, vol.114
, pp. 2193-2196
-
-
Canobbio, I.1
Stefanini, L.2
Cipolla, L.3
Ciraolo, E.4
Gruppi, C.5
Balduini, C.6
Torti, M.7
-
10
-
-
77950423041
-
Deletion of p110β isoform of phosphatidylinositol 3-kinase in platelets reveales its central role in Akt activation and thrombus formation in vitro and in vivo
-
Martin V., Guillermet-Guibert J., Chicanne G., Cabou C., Jandrot-Perrus M., Plantavid M., Vanhaesebroeck B., Payrastre B., Gratacap M.P. Deletion of p110β isoform of phosphatidylinositol 3-kinase in platelets reveales its central role in Akt activation and thrombus formation in vitro and in vivo. Blood 2010, 115:2008-2013.
-
(2010)
Blood
, vol.115
, pp. 2008-2013
-
-
Martin, V.1
Guillermet-Guibert, J.2
Chicanne, G.3
Cabou, C.4
Jandrot-Perrus, M.5
Plantavid, M.6
Vanhaesebroeck, B.7
Payrastre, B.8
Gratacap, M.P.9
-
11
-
-
21044454703
-
PI 3-kinase p110β: a new target for antithrombotic therapy
-
Jackson S.P., Schoenwaelder S.M., Goncalves I., Nesbitt W.S., Yap C.L., Wright C.E., Kenche V., Anderson K.E., Dopheide S.M., Yuan Y., Sturgeon S.A., Prabaharan H., Thompson P.E., Smith G.D., Shepherd P.R., Daniele N., Kulkarni S., Abbott B., Saylik D., Jones C., Lu L., Giuliano S., Hughan S.C., Angus J.A., Robertson A.D., Salem H.H. PI 3-kinase p110β: a new target for antithrombotic therapy. Nat. Med. 2005, 11:507-514.
-
(2005)
Nat. Med.
, vol.11
, pp. 507-514
-
-
Jackson, S.P.1
Schoenwaelder, S.M.2
Goncalves, I.3
Nesbitt, W.S.4
Yap, C.L.5
Wright, C.E.6
Kenche, V.7
Anderson, K.E.8
Dopheide, S.M.9
Yuan, Y.10
Sturgeon, S.A.11
Prabaharan, H.12
Thompson, P.E.13
Smith, G.D.14
Shepherd, P.R.15
Daniele, N.16
Kulkarni, S.17
Abbott, B.18
Saylik, D.19
Jones, C.20
Lu, L.21
Giuliano, S.22
Hughan, S.C.23
Angus, J.A.24
Robertson, A.D.25
Salem, H.H.26
more..
-
12
-
-
21344436415
-
Role of the p110δ PI3-kinase in integrin and ITAM receptor signalling in platelets
-
Senis Y.A., Atkinson B.T., Pearce A.C., Wonerow P., Auger J.M., Okkenhaug K., Pearce W., Vigorito E., Vanhaesebroeck B., Turner M., Watson S.P. Role of the p110δ PI3-kinase in integrin and ITAM receptor signalling in platelets. Platelets 2005, 16:191-202.
-
(2005)
Platelets
, vol.16
, pp. 191-202
-
-
Senis, Y.A.1
Atkinson, B.T.2
Pearce, A.C.3
Wonerow, P.4
Auger, J.M.5
Okkenhaug, K.6
Pearce, W.7
Vigorito, E.8
Vanhaesebroeck, B.9
Turner, M.10
Watson, S.P.11
-
13
-
-
71749121027
-
Non-redundant roles of phosphoinositide 3-kinase isoforms α and β in glycoprotein VI-induced platelet signaling and thrombus formation
-
Gilio K., Munnix I.C., Mangin P., Cosemans J.M., Feijge M.A., van der Meijden P.E., Olieslagers S., Chrzanowska-Wodnicka M.B., Lillian R., Schoenwaelder S., Koyasu S., Sage S.O., Jackson S.P., Heemskerk J.W. Non-redundant roles of phosphoinositide 3-kinase isoforms α and β in glycoprotein VI-induced platelet signaling and thrombus formation. J. Biol. Chem. 2009, 284:33750-33762.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 33750-33762
-
-
Gilio, K.1
Munnix, I.C.2
Mangin, P.3
Cosemans, J.M.4
Feijge, M.A.5
van der Meijden, P.E.6
Olieslagers, S.7
Chrzanowska-Wodnicka, M.B.8
Lillian, R.9
Schoenwaelder, S.10
Koyasu, S.11
Sage, S.O.12
Jackson, S.P.13
Heemskerk, J.W.14
-
14
-
-
77951621262
-
The emerging mechanisms of isoform-specific PI3K signalling
-
Vanhaesebroeck B., Guillermet-Guibert J., Graupera M., Bilanges B. The emerging mechanisms of isoform-specific PI3K signalling. Nat. Rev. Mol. Cell Biol. 2010, 11:329-341.
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 329-341
-
-
Vanhaesebroeck, B.1
Guillermet-Guibert, J.2
Graupera, M.3
Bilanges, B.4
-
15
-
-
84873547290
-
The proline-rich tyrosine kinase Pyk2 regulates platelet integrin αIIbβ3 outside-in signaling
-
Cipolla L., Consonni A., Guidetti G., Canobbio I., Okigaki M., Falasca M., Ciraolo E., Hirsch E., Balduini C., Torti M. The proline-rich tyrosine kinase Pyk2 regulates platelet integrin αIIbβ3 outside-in signaling. J. Thromb. Haemost. 2013, 11:345-356.
-
(2013)
J. Thromb. Haemost.
, vol.11
, pp. 345-356
-
-
Cipolla, L.1
Consonni, A.2
Guidetti, G.3
Canobbio, I.4
Okigaki, M.5
Falasca, M.6
Ciraolo, E.7
Hirsch, E.8
Balduini, C.9
Torti, M.10
-
16
-
-
84896060546
-
Role and regulation of phosphatidylinositol 3-kinase β in platelet integrin α2β1 signaling
-
Consonni A., Cipolla L., Guidetti G., Canobbio I., Ciraolo E., Hirsch E., Falasca M., Okigaki M., Balduini C., Torti M. Role and regulation of phosphatidylinositol 3-kinase β in platelet integrin α2β1 signaling. Blood 2012, 119:847-856.
-
(2012)
Blood
, vol.119
, pp. 847-856
-
-
Consonni, A.1
Cipolla, L.2
Guidetti, G.3
Canobbio, I.4
Ciraolo, E.5
Hirsch, E.6
Falasca, M.7
Okigaki, M.8
Balduini, C.9
Torti, M.10
-
17
-
-
55649084906
-
Phosphoinositide 3-kinase p110β activity: key role in metabolism and mammary gland cancer but not development
-
Ciraolo E., Iezzi M., Marone R., Marengo S., Curcio C., Costa C., Azzolino O., Gonella C., Rubinetto C., Wu H., Dastrù W., Silengo E.L., Altruda F., Turco E., Lanzetti L., Musiani P., Rückle T., Rommel C., Backer J.M., Forni G., Wymann M.P., Hirsch E. Phosphoinositide 3-kinase p110β activity: key role in metabolism and mammary gland cancer but not development. Sci. Signal. 2008, 1:ra3.
-
(2008)
Sci. Signal.
, vol.1
, pp. ra3
-
-
Ciraolo, E.1
Iezzi, M.2
Marone, R.3
Marengo, S.4
Curcio, C.5
Costa, C.6
Azzolino, O.7
Gonella, C.8
Rubinetto, C.9
Wu, H.10
Dastrù, W.11
Silengo, E.L.12
Altruda, F.13
Turco, E.14
Lanzetti, L.15
Musiani, P.16
Rückle, T.17
Rommel, C.18
Backer, J.M.19
Forni, G.20
Wymann, M.P.21
Hirsch, E.22
more..
-
18
-
-
4344714889
-
PI3Kgamma modulates the cardiac response to chronic pressure overload by distinct kinase-dependent and -independent effects
-
Patrucco E., Notte A., Barberis L., Selvetella G., Maffei A., Brancaccio M., Marengo S., Russo G., Azzolino O., Rybalkin S.D., Silengo L., Altruda F., Wetzker R., Wymann M.P., Lembo G., Hirsch E. PI3Kgamma modulates the cardiac response to chronic pressure overload by distinct kinase-dependent and -independent effects. Cell 2004, 118:375-387.
-
(2004)
Cell
, vol.118
, pp. 375-387
-
-
Patrucco, E.1
Notte, A.2
Barberis, L.3
Selvetella, G.4
Maffei, A.5
Brancaccio, M.6
Marengo, S.7
Russo, G.8
Azzolino, O.9
Rybalkin, S.D.10
Silengo, L.11
Altruda, F.12
Wetzker, R.13
Wymann, M.P.14
Lembo, G.15
Hirsch, E.16
-
19
-
-
34548263235
-
Central role of calcium-dependent tyrosine kinase PYK2 in endothelial nitric oxide synthase-mediated angiogenic response and vascular function
-
Matsui A., Okigaki M., Amano K., Adachi Y., Jin D., Takai S., Yamashita T., Kawashima S., Kurihara T., Miyazaki M., Tateishi K., Matsunaga S., Katsume A., Honshou S., Takahashi T., Matoba S., Kusaba T., Tatsumi T., Matsubara H. Central role of calcium-dependent tyrosine kinase PYK2 in endothelial nitric oxide synthase-mediated angiogenic response and vascular function. Circulation 2007, 116:1041-1051.
-
(2007)
Circulation
, vol.116
, pp. 1041-1051
-
-
Matsui, A.1
Okigaki, M.2
Amano, K.3
Adachi, Y.4
Jin, D.5
Takai, S.6
Yamashita, T.7
Kawashima, S.8
Kurihara, T.9
Miyazaki, M.10
Tateishi, K.11
Matsunaga, S.12
Katsume, A.13
Honshou, S.14
Takahashi, T.15
Matoba, S.16
Kusaba, T.17
Tatsumi, T.18
Matsubara, H.19
-
20
-
-
81555196332
-
Tyrosine phosphorylated c-Cbl regulates platelet functional responses mediated by outside-in signaling
-
Buitrago L., Langdon W.Y., Sanjay A., Kunapuli S.P. Tyrosine phosphorylated c-Cbl regulates platelet functional responses mediated by outside-in signaling. Blood 2011, 118:5631-5640.
-
(2011)
Blood
, vol.118
, pp. 5631-5640
-
-
Buitrago, L.1
Langdon, W.Y.2
Sanjay, A.3
Kunapuli, S.P.4
-
21
-
-
84873029127
-
Impaired thrombin-induced platelet activation and thrombus formation in mice lacking the Ca(2+)-dependent tyrosine kinase Pyk2
-
Canobbio I., Cipolla L., Consonni A., Momi S., Guidetti G., Oliviero B., Falasca M., Okigaki M., Balduini C., Gresele P., Torti M. Impaired thrombin-induced platelet activation and thrombus formation in mice lacking the Ca(2+)-dependent tyrosine kinase Pyk2. Blood 2013, 121:648-657.
-
(2013)
Blood
, vol.121
, pp. 648-657
-
-
Canobbio, I.1
Cipolla, L.2
Consonni, A.3
Momi, S.4
Guidetti, G.5
Oliviero, B.6
Falasca, M.7
Okigaki, M.8
Balduini, C.9
Gresele, P.10
Torti, M.11
-
22
-
-
84879027082
-
Phosphorylation of the guanine-nucleotide-exchange factor CalDAG-GEFI by protein kinase A regulates Ca(2+) dependent activation of platelet Rap1b GTPase
-
Guidetti G.F., Manganaro D., Consonni A., Canobbio I., Balduini C., Torti M. Phosphorylation of the guanine-nucleotide-exchange factor CalDAG-GEFI by protein kinase A regulates Ca(2+) dependent activation of platelet Rap1b GTPase. Biochem. J. 2013, 453:115-123.
-
(2013)
Biochem. J.
, vol.453
, pp. 115-123
-
-
Guidetti, G.F.1
Manganaro, D.2
Consonni, A.3
Canobbio, I.4
Balduini, C.5
Torti, M.6
-
23
-
-
0033531952
-
Rap1B and Rap2B translocation to the cytoskeleton by von Willebrand factor involves FcγIIA receptor-mediated protein tyrosine phosphorylation
-
Torti M., Bertoni A., Canobbio I., Sinigaglia F., Lapetina E.G., Balduini C. Rap1B and Rap2B translocation to the cytoskeleton by von Willebrand factor involves FcγIIA receptor-mediated protein tyrosine phosphorylation. J. Biol. Chem. 1999, 274:13690-13697.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 13690-13697
-
-
Torti, M.1
Bertoni, A.2
Canobbio, I.3
Sinigaglia, F.4
Lapetina, E.G.5
Balduini, C.6
-
24
-
-
32144455870
-
A new role for FcγRIIA in the potentiation of human platelet activation induced by weak stimulation
-
Canobbio I., Stefanini L., Guidetti G.F., Balduini C., Torti M. A new role for FcγRIIA in the potentiation of human platelet activation induced by weak stimulation. Cell. Signal. 2006, 18:861-870.
-
(2006)
Cell. Signal.
, vol.18
, pp. 861-870
-
-
Canobbio, I.1
Stefanini, L.2
Guidetti, G.F.3
Balduini, C.4
Torti, M.5
-
25
-
-
0037424877
-
Platelet interaction with CNBr peptides from type II collagen via integrin α2β1
-
Guidetti G.F., Greco F., Bertoni A., Giudici C., Viola M., Tenni R., Tira E.M., Balduini C., Torti M. Platelet interaction with CNBr peptides from type II collagen via integrin α2β1. Biochim. Biophys. Acta 2003, 1640:43-51.
-
(2003)
Biochim. Biophys. Acta
, vol.1640
, pp. 43-51
-
-
Guidetti, G.F.1
Greco, F.2
Bertoni, A.3
Giudici, C.4
Viola, M.5
Tenni, R.6
Tira, E.M.7
Balduini, C.8
Torti, M.9
-
26
-
-
4444224120
-
C-Cbl negatively regulates platelet activation by glycoprotein VI
-
Auger J.M., Best D., Snell D.C., Wilde J.I., Watson S.P. c-Cbl negatively regulates platelet activation by glycoprotein VI. J. Thromb. Haemost. 2003, 1:2419-2426.
-
(2003)
J. Thromb. Haemost.
, vol.1
, pp. 2419-2426
-
-
Auger, J.M.1
Best, D.2
Snell, D.C.3
Wilde, J.I.4
Watson, S.P.5
-
27
-
-
18244368702
-
Focal adhesion kinase-related protein tyrosine kinase Pyk2 in T-cell activation and function
-
Ostergaard H.L., Lysechko T.L. Focal adhesion kinase-related protein tyrosine kinase Pyk2 in T-cell activation and function. Immunol. Res. 2005, 31:267-282.
-
(2005)
Immunol. Res.
, vol.31
, pp. 267-282
-
-
Ostergaard, H.L.1
Lysechko, T.L.2
-
28
-
-
57649198313
-
The Gi-coupled P2Y12 receptor regulates diacylglycerol-mediated signaling in human platelets
-
Guidetti G.F., Lova P., Bernardi B., Campus F., Baldanzi G., Graziani A., Balduini C., Torti M. The Gi-coupled P2Y12 receptor regulates diacylglycerol-mediated signaling in human platelets. J. Biol. Chem. 2008, 283:28795-28805.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 28795-28805
-
-
Guidetti, G.F.1
Lova, P.2
Bernardi, B.3
Campus, F.4
Baldanzi, G.5
Graziani, A.6
Balduini, C.7
Torti, M.8
-
29
-
-
84880853198
-
Cbl proteins in platelet activation
-
Buitrago L., Tsygankov A., Sanjay A., Kunapuli S.P. Cbl proteins in platelet activation. Platelets 2013, 24:419-427.
-
(2013)
Platelets
, vol.24
, pp. 419-427
-
-
Buitrago, L.1
Tsygankov, A.2
Sanjay, A.3
Kunapuli, S.P.4
-
30
-
-
0033593215
-
Fc receptor-mediated platelet activation is dependent on phosphatidylinositol 3-kinase activation and involves p120(Cbl)
-
Saci A., Pain S., Rendu F., Bachelot-Loza C. Fc receptor-mediated platelet activation is dependent on phosphatidylinositol 3-kinase activation and involves p120(Cbl). J. Biol. Chem. 1999, 274:1898-1904.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 1898-1904
-
-
Saci, A.1
Pain, S.2
Rendu, F.3
Bachelot-Loza, C.4
-
31
-
-
0034332635
-
Platelet αIIbβ3 integrin engagement induces the tyrosine phosphorylation of Cbl and its association with phosphoinositide 3-kinase and Syk
-
Saci A., Rendu F., Bachelot-Loza C. Platelet αIIbβ3 integrin engagement induces the tyrosine phosphorylation of Cbl and its association with phosphoinositide 3-kinase and Syk. Biochem. J. 2000, 351:669-676.
-
(2000)
Biochem. J.
, vol.351
, pp. 669-676
-
-
Saci, A.1
Rendu, F.2
Bachelot-Loza, C.3
-
32
-
-
77952940634
-
Cbl-b is a novel physiologic regulator of glycoprotein VI-dependent platelet activation
-
Daniel J.L., Dangelmaier C.A., Mada S., Buitrago L., Jin J., Langdon W.Y., Tsygankov A.Y., Kunapuli S.P., Sanjay A. Cbl-b is a novel physiologic regulator of glycoprotein VI-dependent platelet activation. J. Biol. Chem. 2010, 285:17282-17291.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 17282-17291
-
-
Daniel, J.L.1
Dangelmaier, C.A.2
Mada, S.3
Buitrago, L.4
Jin, J.5
Langdon, W.Y.6
Tsygankov, A.Y.7
Kunapuli, S.P.8
Sanjay, A.9
-
33
-
-
0032518666
-
Activation of phospholipase Cγ by PI 3-kinase-induced PH domain-mediated membrane targeting
-
Falasca M., Logan S.K., Lehto V.P., Baccante G., Lemmon M.A., Schlessinger J. Activation of phospholipase Cγ by PI 3-kinase-induced PH domain-mediated membrane targeting. EMBO J. 1998, 17:414-422.
-
(1998)
EMBO J.
, vol.17
, pp. 414-422
-
-
Falasca, M.1
Logan, S.K.2
Lehto, V.P.3
Baccante, G.4
Lemmon, M.A.5
Schlessinger, J.6
-
34
-
-
0033567185
-
A collagen-related peptide regulates phospholipase Cγ2 via phosphatidylinositol 3-kinase in human platelets
-
Pasquet J.M., Bobe R., Gross B., Gratacap M.P., Tomlinson M.G., Payrastre B., Watson S.P. A collagen-related peptide regulates phospholipase Cγ2 via phosphatidylinositol 3-kinase in human platelets. Biochem. J. 1999, 342:171-177.
-
(1999)
Biochem. J.
, vol.342
, pp. 171-177
-
-
Pasquet, J.M.1
Bobe, R.2
Gross, B.3
Gratacap, M.P.4
Tomlinson, M.G.5
Payrastre, B.6
Watson, S.P.7
|