SIRT1 activating compounds reduce oxidative stress and prevent cell death in neuronal cells

Frontiers in Cellular Neuroscience

Volumn , Issue DEC, 2012, Pages

  Khan, Reas S ^a   Fonseca Kelly, Zoe ^a   Callinan, Catherine ^b   Zuo, Ling ^c   Sachdeva, Mira M ^d   Shindler, Kenneth S ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c THE SECOND HOSPITAL OF JILIN UNIVERSITY   (China)

^d JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Mitochondria; Neuroprotection; Optic neuropathy; Oxidative stress; Resveratrol; SIRT1

Indexed keywords

ANTIOXIDANT; NEUROPROTECTIVE AGENT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; REACTIVE OXYGEN METABOLITE; RESVERATROL; SIRTUIN 1; SMALL INTERFERING RNA; SRTAW 04; SUCCINATE DEHYDROGENASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; CELL ASSAY; CELL DEATH; CELL LOSS; CELL SURVIVAL; CONTROLLED STUDY; DEACETYLATION; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NEUROPROTECTION; NEWBORN; NONHUMAN; OPTIC NEURITIS; OXIDATIVE STRESS; PROTEIN EXPRESSION;

EID: 84898563412     PISSN: 16625102     EISSN: None     Source Type: Journal    
DOI: 10.3389/fncel.2012.00063     Document Type: Article

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