메뉴 건너뛰기




Volumn 6, Issue , 2015, Pages

Alternatively activated macrophages promote pancreatic fibrosis in chronic pancreatitis

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 4 RECEPTOR ALPHA; CELL SURFACE RECEPTOR; IL4 PROTEIN, HUMAN; IL4R PROTEIN, HUMAN; IL4RA PROTEIN, MOUSE; PEPTIDE;

EID: 84929347258     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms8158     Document Type: Article
Times cited : (289)

References (43)
  • 1
    • 0028905980 scopus 로고
    • Development of chronic pancreatitis from acute pancreatitis: A pathogenetic concept
    • Kloppel, G. & Maillet, B. [Development of chronic pancreatitis from acute pancreatitis: a pathogenetic concept]. Zentralbl. Chir. 120, 274-277 (1995).
    • (1995) Zentralbl. Chir. , vol.120 , pp. 274-277
    • Kloppel, G.1    Maillet, B.2
  • 2
    • 0022551284 scopus 로고
    • Etiopathogenesis and definition of chronic pancreatitis
    • Sarles, H. Etiopathogenesis and definition of chronic pancreatitis. Dig. Dis. Sci. 31, 91S-107S (1986).
    • (1986) Dig. Dis. Sci. , vol.31 , pp. 91S-107S
    • Sarles, H.1
  • 3
    • 34248345864 scopus 로고    scopus 로고
    • Chronic pancreatitis, pseudotumors and other tumor-like lesions
    • Kloppel, G. Chronic pancreatitis, pseudotumors and other tumor-like lesions. Mod. Pathol. 20(Suppl 1): S113-S131 (2007).
    • (2007) Mod. Pathol. , vol.20 , pp. S113-S131
    • Kloppel, G.1
  • 4
    • 34247197621 scopus 로고    scopus 로고
    • Chronic pancreatitis: Challenges and advances in pathogenesis, genetics, diagnosis, and therapy
    • Witt, H., Apte, M. V., Keim, V. & Wilson, J. S. Chronic pancreatitis: challenges and advances in pathogenesis, genetics, diagnosis, and therapy. Gastroenterology 132, 1557-1573 (2007).
    • (2007) Gastroenterology , vol.132 , pp. 1557-1573
    • Witt, H.1    Apte, M.V.2    Keim, V.3    Wilson, J.S.4
  • 5
    • 80054031046 scopus 로고    scopus 로고
    • The fibrosis of chronic pancreatitis: New insights into the role of pancreatic stellate cells
    • Apte, M., Pirola, R. & Wilson, J. The fibrosis of chronic pancreatitis: new insights into the role of pancreatic stellate cells. Antioxid. Redox Signal 15, 2711-2722 (2011).
    • (2011) Antioxid. Redox Signal , vol.15 , pp. 2711-2722
    • Apte, M.1    Pirola, R.2    Wilson, J.3
  • 6
    • 33845998896 scopus 로고    scopus 로고
    • The pancreatic stellate cell: A star on the rise in pancreatic diseases
    • Omary, M. B., Lugea, A., Lowe, A. W. & Pandol, S. J. The pancreatic stellate cell: a star on the rise in pancreatic diseases. J. Clin. Invest. 117, 50-59 (2007).
    • (2007) J. Clin. Invest. , vol.117 , pp. 50-59
    • Omary, M.B.1    Lugea, A.2    Lowe, A.W.3    Pandol, S.J.4
  • 7
    • 33644654915 scopus 로고    scopus 로고
    • Molecular mechanisms of alcoholic pancreatitis
    • Apte, M. V., Pirola, R. C. & Wilson, J. S. Molecular mechanisms of alcoholic pancreatitis. Dig. Dis. 23, 232-240 (2005).
    • (2005) Dig. Dis. , vol.23 , pp. 232-240
    • Apte, M.V.1    Pirola, R.C.2    Wilson, J.S.3
  • 8
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • Gordon, S. Alternative activation of macrophages. Nat. Rev. Immunol. 3, 23-35 (2003).
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 23-35
    • Gordon, S.1
  • 9
    • 77954961992 scopus 로고    scopus 로고
    • Macrophages: Master regulators of inflammation and fibrosis
    • Wynn, T. A. & Barron, L. Macrophages: master regulators of inflammation and fibrosis. Semin. Liver Dis. 30, 245-257 (2010).
    • (2010) Semin. Liver Dis. , vol.30 , pp. 245-257
    • Wynn, T.A.1    Barron, L.2
  • 10
    • 84863702343 scopus 로고    scopus 로고
    • Mechanisms of fibrosis: Therapeutic translation for fibrotic disease
    • Wynn, T. A. & Ramalingam, T. R. Mechanisms of fibrosis: therapeutic translation for fibrotic disease. Nat. Med. 18, 1028-1040 (2012).
    • (2012) Nat. Med. , vol.18 , pp. 1028-1040
    • Wynn, T.A.1    Ramalingam, T.R.2
  • 11
    • 33746297322 scopus 로고    scopus 로고
    • Fibrogenesis in alcoholic chronic pancreatitis: The role of tissue necrosis, macrophages, myofibroblasts and cytokines
    • Detlefsen, S., Sipos, B., Feyerabend, B. & Kloppel, G. Fibrogenesis in alcoholic chronic pancreatitis: the role of tissue necrosis, macrophages, myofibroblasts and cytokines. Mod. Pathol. 19, 1019-1026 (2006).
    • (2006) Mod. Pathol. , vol.19 , pp. 1019-1026
    • Detlefsen, S.1    Sipos, B.2    Feyerabend, B.3    Kloppel, G.4
  • 12
    • 11144237484 scopus 로고    scopus 로고
    • Chronic alcohol consumption accelerates fibrosis in response to cerulein-induced pancreatitis in rats
    • Deng, X. et al. Chronic alcohol consumption accelerates fibrosis in response to cerulein-induced pancreatitis in rats. Am. J. Pathol. 166, 93-106 (2005).
    • (2005) Am. J. Pathol. , vol.166 , pp. 93-106
    • Deng, X.1
  • 13
    • 84876794306 scopus 로고    scopus 로고
    • Relevance of animal models of pancreatic cancer and pancreatitis to human disease
    • Saluja, A. K. & Dudeja, V. Relevance of animal models of pancreatic cancer and pancreatitis to human disease. Gastroenterology 144, 1194-1198 (2013).
    • (2013) Gastroenterology , vol.144 , pp. 1194-1198
    • Saluja, A.K.1    Dudeja, V.2
  • 14
    • 84876788888 scopus 로고    scopus 로고
    • Models of acute and chronic pancreatitis
    • Lerch, M. M. & Gorelick, F. S. Models of acute and chronic pancreatitis. Gastroenterology 144, 1180-1193 (2013).
    • (2013) Gastroenterology , vol.144 , pp. 1180-1193
    • Lerch, M.M.1    Gorelick, F.S.2
  • 15
    • 84874606609 scopus 로고    scopus 로고
    • IL-6 trans-signaling promotes pancreatitis-associated lung injury and lethality
    • Zhang, H. et al. IL-6 trans-signaling promotes pancreatitis-associated lung injury and lethality. J. Clin. Invest. 123, 1019-1031 (2013).
    • (2013) J. Clin. Invest. , vol.123 , pp. 1019-1031
    • Zhang, H.1
  • 16
    • 84886816349 scopus 로고    scopus 로고
    • IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1
    • Jenkins, S. J. et al. IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1. J. Exp. Med. 210, 2477-2491 (2013).
    • (2013) J. Exp. Med. , vol.210 , pp. 2477-2491
    • Jenkins, S.J.1
  • 17
    • 84859398141 scopus 로고    scopus 로고
    • CCL2-induced migration and SOCS3-mediated activation of macrophages are involved in cerulein-induced pancreatitis in mice
    • e1019
    • Saeki, K. et al. CCL2-induced migration and SOCS3-mediated activation of macrophages are involved in cerulein-induced pancreatitis in mice. Gastroenterology 142, 1010-1020 e1019 (2012).
    • (2012) Gastroenterology , vol.142 , pp. 1010-1020
    • Saeki, K.1
  • 18
    • 33645902493 scopus 로고    scopus 로고
    • Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2
    • Serbina, N. V. & Pamer, E. G. Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2. Nat. Immunol. 7, 311-317 (2006).
    • (2006) Nat. Immunol. , vol.7 , pp. 311-317
    • Serbina, N.V.1    Pamer, E.G.2
  • 19
    • 79953678939 scopus 로고    scopus 로고
    • Obstacles and opportunities for understanding macrophage polarization
    • Murray, P. J. & Wynn, T. A. Obstacles and opportunities for understanding macrophage polarization. J. Leukoc. Biol. 89, 557-563 (2011).
    • (2011) J. Leukoc. Biol. , vol.89 , pp. 557-563
    • Murray, P.J.1    Wynn, T.A.2
  • 20
    • 84904394690 scopus 로고    scopus 로고
    • Macrophage activation and polarization: Nomenclature and experimental guidelines
    • Murray, P. J. et al. Macrophage activation and polarization: nomenclature and experimental guidelines. Immunity 41, 14-20 (2014).
    • (2014) Immunity , vol.41 , pp. 14-20
    • Murray, P.J.1
  • 21
    • 84857883847 scopus 로고    scopus 로고
    • Macrophage plasticity and polarization: In vivo veritas
    • Sica, A. & Mantovani, A. Macrophage plasticity and polarization: in vivo veritas. J. Clin. Invest. 122, 787-795 (2012).
    • (2012) J. Clin. Invest. , vol.122 , pp. 787-795
    • Sica, A.1    Mantovani, A.2
  • 22
    • 80355131976 scopus 로고    scopus 로고
    • Protective and pathogenic functions of macrophage subsets
    • Murray, P. J. & Wynn, T. A. Protective and pathogenic functions of macrophage subsets. Nat. Rev. Immunol. 11, 723-737 (2011).
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 723-737
    • Murray, P.J.1    Wynn, T.A.2
  • 23
    • 82555186955 scopus 로고    scopus 로고
    • Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis
    • Nguyen, K. D. et al. Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis. Nature 480, 104-108 (2011).
    • (2011) Nature , vol.480 , pp. 104-108
    • Nguyen, K.D.1
  • 24
    • 2442717844 scopus 로고    scopus 로고
    • Alternative macrophage activation is essential for survival during schistosomiasis and downmodulates T helper 1 responses and immunopathology
    • Herbert, D. R. et al. Alternative macrophage activation is essential for survival during schistosomiasis and downmodulates T helper 1 responses and immunopathology. Immunity 20, 623-635 (2004).
    • (2004) Immunity , vol.20 , pp. 623-635
    • Herbert, D.R.1
  • 25
    • 37249092998 scopus 로고    scopus 로고
    • Pancreatic stellate cells: New target in the treatment of chronic pancreatitis
    • Talukdar, R. & Tandon, R. K. Pancreatic stellate cells: new target in the treatment of chronic pancreatitis. J. Gastroenterol. Hepatol. 23, 34-41 (2008).
    • (2008) J. Gastroenterol. Hepatol. , vol.23 , pp. 34-41
    • Talukdar, R.1    Tandon, R.K.2
  • 26
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the full spectrum of macrophage activation
    • Mosser, D. M. & Edwards, J. P. Exploring the full spectrum of macrophage activation. Nat. Rev. Immunol. 8, 958-969 (2008).
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 958-969
    • Mosser, D.M.1    Edwards, J.P.2
  • 27
    • 77957940963 scopus 로고    scopus 로고
    • Exercise training inhibits inflammation in adipose tissue via both suppression of macrophage infiltration and acceleration of phenotypic switching from M1 to M2 macrophages in high-fat-diet-induced obese mice
    • Kawanishi, N., Yano, H., Yokogawa, Y. & Suzuki, K. Exercise training inhibits inflammation in adipose tissue via both suppression of macrophage infiltration and acceleration of phenotypic switching from M1 to M2 macrophages in high-fat-diet-induced obese mice. Exerc. Immunol. Rev. 16, 105-118 (2010).
    • (2010) Exerc. Immunol. Rev. , vol.16 , pp. 105-118
    • Kawanishi, N.1    Yano, H.2    Yokogawa, Y.3    Suzuki, K.4
  • 28
    • 0032954505 scopus 로고    scopus 로고
    • Pancreatic stellate cells are activated by proinflammatory cytokines: Implications for pancreatic fibrogenesis
    • Apte, M. V. et al. Pancreatic stellate cells are activated by proinflammatory cytokines: implications for pancreatic fibrogenesis. Gut 44, 534-541 (1999).
    • (1999) Gut , vol.44 , pp. 534-541
    • Apte, M.V.1
  • 29
    • 0036098613 scopus 로고    scopus 로고
    • Expression of transforming growth factor-beta 1 by pancreatic stellate cells and its implications for matrix secretion and turnover in chronic pancreatitis
    • Shek, F. W. et al. Expression of transforming growth factor-beta 1 by pancreatic stellate cells and its implications for matrix secretion and turnover in chronic pancreatitis. Am. J. Pathol. 160, 1787-1798 (2002).
    • (2002) Am. J. Pathol. , vol.160 , pp. 1787-1798
    • Shek, F.W.1
  • 30
    • 21244443731 scopus 로고    scopus 로고
    • Macrophages sequentially change their functional phenotype in response to changes in microenvironmental influences
    • Stout, R. D. et al. Macrophages sequentially change their functional phenotype in response to changes in microenvironmental influences. J. Immunol. 175, 342-349 (2005).
    • (2005) J. Immunol. , vol.175 , pp. 342-349
    • Stout, R.D.1
  • 31
    • 4344706372 scopus 로고    scopus 로고
    • Functional plasticity of macrophages: Reversible adaptation to changing microenvironments
    • Stout, R. D. & Suttles, J. Functional plasticity of macrophages: reversible adaptation to changing microenvironments. J. Leukoc. Biol. 76, 509-513 (2004).
    • (2004) J. Leukoc. Biol. , vol.76 , pp. 509-513
    • Stout, R.D.1    Suttles, J.2
  • 32
    • 28344449833 scopus 로고    scopus 로고
    • Macrophage activation switching: An asset for the resolution of inflammation
    • Porcheray, F. et al. Macrophage activation switching: an asset for the resolution of inflammation. Clin. Exp. Immunol. 142, 481-489 (2005).
    • (2005) Clin. Exp. Immunol. , vol.142 , pp. 481-489
    • Porcheray, F.1
  • 33
    • 84875544506 scopus 로고    scopus 로고
    • Interleukin-4-and interleukin-13-mediated alternatively activated macrophages: Roles in homeostasis and disease
    • Van Dyken, S. J. & Locksley, R. M. Interleukin-4-and interleukin-13-mediated alternatively activated macrophages: roles in homeostasis and disease. Annu. Rev. Immunol. 31, 317-343 (2013).
    • (2013) Annu. Rev. Immunol. , vol.31 , pp. 317-343
    • Van Dyken, S.J.1    Locksley, R.M.2
  • 34
    • 0035903306 scopus 로고    scopus 로고
    • Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1)
    • Lee, C. G. et al. Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1). J. Exp. Med. 194, 809-821 (2001).
    • (2001) J. Exp. Med. , vol.194 , pp. 809-821
    • Lee, C.G.1
  • 35
    • 33845752914 scopus 로고    scopus 로고
    • P50 nuclear factor-kappaB overexpression in tumor-associated macrophages inhibits M1 inflammatory responses and antitumor resistance
    • Saccani, A. et al. p50 nuclear factor-kappaB overexpression in tumor-associated macrophages inhibits M1 inflammatory responses and antitumor resistance. Cancer Res. 66, 11432-11440 (2006).
    • (2006) Cancer Res. , vol.66 , pp. 11432-11440
    • Saccani, A.1
  • 36
    • 17144398046 scopus 로고    scopus 로고
    • Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection
    • Guiducci, C., Vicari, A. P., Sangaletti, S., Trinchieri, G. & Colombo, M. P. Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection. Cancer Res. 65, 3437-3446 (2005).
    • (2005) Cancer Res. , vol.65 , pp. 3437-3446
    • Guiducci, C.1    Vicari, A.P.2    Sangaletti, S.3    Trinchieri, G.4    Colombo, M.P.5
  • 37
    • 0033577811 scopus 로고    scopus 로고
    • Simultaneous disruption of interleukin (IL)-4 and IL-13 defines individual roles in T helper cell type 2-mediated responses
    • McKenzie, G. J., Fallon, P. G., Emson, C. L., Grencis, R. K. & McKenzie, A. N. Simultaneous disruption of interleukin (IL)-4 and IL-13 defines individual roles in T helper cell type 2-mediated responses. J. Exp. Med. 189, 1565-1572 (1999).
    • (1999) J. Exp. Med. , vol.189 , pp. 1565-1572
    • McKenzie, G.J.1    Fallon, P.G.2    Emson, C.L.3    Grencis, R.K.4    McKenzie, A.N.5
  • 38
    • 84869754821 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor regulates pancreatic IL-22 production and protects mice from acute pancreatitis
    • Xue, J., Nguyen, D. T. & Habtezion, A. Aryl hydrocarbon receptor regulates pancreatic IL-22 production and protects mice from acute pancreatitis. Gastroenterology 143, 1670-1680 (2012).
    • (2012) Gastroenterology , vol.143 , pp. 1670-1680
    • Xue, J.1    Nguyen, D.T.2    Habtezion, A.3
  • 39
    • 84892922204 scopus 로고    scopus 로고
    • Carbon monoxide-based therapy ameliorates acute pancreatitis via TLR4 inhibition
    • Xue, J. & Habtezion, A. Carbon monoxide-based therapy ameliorates acute pancreatitis via TLR4 inhibition. J. Clin. Invest. 124, 437-447 (2014).
    • (2014) J. Clin. Invest. , vol.124 , pp. 437-447
    • Xue, J.1    Habtezion, A.2
  • 40
    • 80053588704 scopus 로고    scopus 로고
    • Myeloid, but not pancreatic, RelA/p65 is required for fibrosis in a mouse model of chronic pancreatitis
    • Treiber, M. et al. Myeloid, but not pancreatic, RelA/p65 is required for fibrosis in a mouse model of chronic pancreatitis. Gastroenterology 141, e1471-e1477 (2011).
    • (2011) Gastroenterology , vol.141 , pp. e1471-e1477
    • Treiber, M.1
  • 41
    • 5444247172 scopus 로고    scopus 로고
    • Identification, culture, and characterization of pancreatic stellate cells in rats and humans
    • Bachem, M. G. et al. Identification, culture, and characterization of pancreatic stellate cells in rats and humans. Gastroenterology 115, 421-432 (1998).
    • (1998) Gastroenterology , vol.115 , pp. 421-432
    • Bachem, M.G.1
  • 42
    • 0031842971 scopus 로고    scopus 로고
    • Periacinar stellate shaped cells in rat pancreas: Identification, isolation, and culture
    • Apte, M. V. et al. Periacinar stellate shaped cells in rat pancreas: identification, isolation, and culture. Gut 43, 128-133 (1998).
    • (1998) Gut , vol.43 , pp. 128-133
    • Apte, M.V.1
  • 43
    • 84856248594 scopus 로고    scopus 로고
    • Isolation and differentiation of monocytes-macrophages from human blood
    • Vijayan, D. Isolation and differentiation of monocytes-macrophages from human blood. Methods Mol. Biol. 844, 183-187 (2012).
    • (2012) Methods Mol. Biol. , vol.844 , pp. 183-187
    • Vijayan, D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.