Examining the neuroprotective effects of protocatechuic acid and chrysin on in vitro and in vivo models of Parkinson disease

Free Radical Biology and Medicine

Volumn 84, Issue , 2015, Pages 331-343

  Zhang, Zaijun ^b,c   Li, Guohui ^a   Szeto, Samuel S W ^a   Chong, Cheong Meng ^c   Quan, Quan ^a   Huang, Chen ^c   Cui, Wei ^d   Guo, Baojian ^b   Wang, Yuqiang ^b   Han, Yifan ^d   Michael Siu, K W ^e   Yuen Lee, Simon Ming ^c   Chu, Ivan K ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b JINAN UNIVERSITY   (China)

^c China jack1987168 163com   (Macao)

^d HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

^e UNIVERSITY OF WINDSOR   (Canada)

Author keywords

Anti inflammation; Freeradicals; Neuroprotection; NRF2 NF B; Parkinsondisease; Proteomics

Indexed keywords

CATALASE; CHRYSIN; HEME OXYGENASE 1; INDUCIBLE NITRIC OXIDE SYNTHASE; LACTATE DEHYDROGENASE; MALONALDEHYDE; NITRIC OXIDE; NUCLEOLIN; OXIDOPAMINE; PROTOCATECHUIC ACID; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; SELEGILINE; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2; TRANSCRIPTION FACTOR RELA; ANTIPARKINSON AGENT; FLAVONOID; HYDROXYBENZOIC ACID DERIVATIVE; NEUROPROTECTIVE AGENT; NFE2L2 PROTEIN, RAT; NOS2 PROTEIN, RAT; PROTEOME; RELA PROTEIN, RAT;

ALPINIA; ALPINIA OXYPHYLLA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; DRUG MECHANISM; DRUG POTENTIATION; EMBRYO; ENZYME RELEASE; FRUIT; GENE EXPRESSION; HYPOKINESIA; IN VITRO STUDY; IN VIVO STUDY; LIPID PEROXIDATION; MOUSE; NEUROLOGIC GAIT DISORDER; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PARKINSON DISEASE; PC12 CELL LINE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEOMICS; RAT; SUBSTANTIA NIGRA PARS COMPACTA; TRANSCRIPTION INITIATION; UPREGULATION; ZEBRA FISH; ANIMAL; DRUG EFFECTS; DRUG SCREENING; METABOLISM; PHYSIOLOGY;

ALPINIA OXYPHYLLA; DANIO RERIO; MUS;

ANIMALS; ANTIPARKINSON AGENTS; DOPAMINERGIC NEURONS; DRUG EVALUATION, PRECLINICAL; FLAVONOIDS; HEME OXYGENASE-1; HYDROXYBENZOATES; NEUROPROTECTIVE AGENTS; NF-E2-RELATED FACTOR 2; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; PARKINSON DISEASE; PC12 CELLS; PROTEOME; PROTEOMICS; RATS; TRANSCRIPTION FACTOR RELA; ZEBRAFISH;

EID: 84929314242     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2015.02.030     Document Type: Article

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