Proteomics of Caenorhabditis elegans over-expressing human α-synuclein analyzed by fluorogenic derivatization-liquid chromatography/tandem mass spectrometry: Identification of actin and several ribosomal proteins as negative markers at early Parkinson's disease stages

Biomedical Chromatography

Volumn 22, Issue 3, 2008, Pages 232-234

  Ichibangase, Tomoko ^a   Saimaru, Hiroshi ^a   Takamura, Norio ^a   Kuwahara, Tomoki ^b   Koyama, Akihiko ^b   Iwatsubo, Takeshi ^b   Imai, Kazuhiro ^a  

^a MUSASHINO UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Caenorhabditis elegans; FD LC MS MS method; Parkinson's disease; Proteome; synuclein

Indexed keywords

FINITE DIFFERENCE METHOD; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOLECULAR BIOLOGY; NEURODEGENERATIVE DISEASES;

CAENORHABDITIS ELEGANS; DERIVATIZATIONS; FD-LC-MS/MS METHOD; FLUOROGENICS; LC-MS-MS; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY/TANDEM MASS SPECTROMETRY; PARKINSON'S DISEASE; WILD TYPES; Α-SYNUCLEIN;

PROTEINS;

ACTIN; ALPHA SYNUCLEIN; DOPAMINE; ENHANCED GREEN FLUORESCENT PROTEIN; RIBOSOME PROTEIN;

ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; DERIVATIZATION; DISEASE COURSE; DISEASE MARKER; DISEASE MODEL; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LEWY BODY; LIQUID CHROMATOGRAPHY; NERVE CELL DEGENERATION; NONHUMAN; PARKINSON DISEASE; PATHOGENESIS; POLYMERASE CHAIN REACTION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN TARGETING; PROTEOMICS; QUANTITATIVE ANALYSIS; REPRODUCIBILITY; SENSITIVITY ANALYSIS; TANDEM MASS SPECTROMETRY; TRANSGENICS; WILD TYPE;

CAENORHABDITIS ELEGANS;

EID: 41549097831     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.931     Document Type: Article

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