The complement receptor C5aR controls acute inflammation and astrogliosis following spinal cord injury

Journal of Neuroscience

Volumn 35, Issue 16, 2015, Pages 6517-6531

  Brennan, Faith H ^a   Gordon, Richard ^a   Lao, Hong W ^a   Biggins, Patrick J ^a   Taylor, Stephen M ^a   Franklin, Robin J M ^b   Woodruff, Trent M ^a   Ruitenberg, Marc J ^a,b,c  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c Diamantina Health Partners   (Australia)

Author keywords

Anaphylatoxin; CNS trauma; Demyelinating pathology; Macrophage; Oligodendrocyte precursor cell; Secondary degeneration

Indexed keywords

ALANINE DERIVATIVE; COMPLEMENT COMPONENT C5A; COMPLEMENT COMPONENT C5A RECEPTOR; CXCL1 CHEMOKINE; GENTAMICIN; HYDROCINNAMIC ACID; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; STAT3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; CYCLOPEPTIDE; HYDROCINNAMATE-(OP(PHE)WR);

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTOSIS; BRDU ASSAY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ELECTROBLOTTING; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPERIMENTAL LOCOMOTOR ACTIVITY TEST; FEMALE; FLOW CYTOMETRY; GRANULOCYTE; HISTOPATHOLOGY; IMMUNOCYTOCHEMISTRY; IMMUNOFLUORESCENCE; INFLAMMATION; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SPINAL CORD INJURY; STEREOMICROSCOPY; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; ASTROCYTE; BIOSYNTHESIS; CELL CULTURE; CELL PROLIFERATION; COMPLEMENT ACTIVATION; COMPLICATION; CONVALESCENCE; DRUG EFFECTS; GENETICS; GLIOSIS; KNOCKOUT MOUSE; METABOLISM; MOTOR ACTIVITY; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SPINAL CORD INJURIES;

ANIMALS; ASTROCYTES; CELL PROLIFERATION; CELLS, CULTURED; COMPLEMENT ACTIVATION; COMPLEMENT C5A; FEMALE; GLIOSIS; INFLAMMATION; MICE; MICE, KNOCKOUT; MOTOR ACTIVITY; PEPTIDES, CYCLIC; RECEPTOR, ANAPHYLATOXIN C5A; RECOVERY OF FUNCTION; SPINAL CORD INJURIES;

EID: 84929309810     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5218-14.2015     Document Type: Article

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