SCOPUS 정보 검색 플랫폼

European Journal of Medicinal Chemistry

Volumn 94, Issue , 2015, Pages 471-479

Lead discovery and optimization strategies for peptide macrocycles

(3) Bhat, Abhijit a Roberts, Lee R b Dwyer, John J c

a IPSEN (France)

b PFIZER INC (United States)

c Ferring Pharmaceuticals AS (Denmark)

Author keywords

Macrocycles; Mrna display; Peptides; Phage display; PPI

Indexed keywords

MACROCYCLIC COMPOUND; PEPTIDE;

CHEMISTRY; CYCLIZATION; DRUG DEVELOPMENT; HUMAN; PROTEIN STABILITY; SYNTHESIS;

CYCLIZATION; DRUG DISCOVERY; HUMANS; MACROCYCLIC COMPOUNDS; PEPTIDES; PROTEIN STABILITY;

EID: 84929175342 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2014.07.083 Document Type: Article

Times cited : (65)

References (46)

1
- 84939886326
- Tufts Center For Study Of Drug Development
- Tufts Center for Study of Drug Development Impact Rep. 15 2013 6
- (2013) Impact Rep , vol.15 , pp. 6

2
- 84939922432
- In collaboration with Janice Reichert, Reichert Biotechnology Consulting LLC. With information from following source: Peptides (Peptide Therapeutic Foundation); and Antibodies (RBC, LLC), Small molecule (Sagient Research) and Di Masi et al. Clin. Pharmacol. Ther. 87 (2010) 272-277
- In collaboration with Janice Reichert, Reichert Biotechnology Consulting LLC. With information from following source: Peptides (Peptide Therapeutic Foundation); and Antibodies (RBC, LLC), Small molecule (Sagient Research) and Di Masi et al. Clin. Pharmacol. Ther. 87 (2010) 272-277.

3
- 84900783354
- C. Sheridan Nat. Biotechnol. 31 2013 1057 1058
- (2013) Nat. Biotechnol , vol.31 , pp. 1057-1058
- Sheridan, C.¹

4
- 77952542911
- S. Dandapani L.A. Marcaurelle Curr. Opin. Chem. Biol. 14 3 2010 362 370
- (2010) Curr. Opin. Chem. Biol , vol.14 , Issue.3 , pp. 362-370
- Dandapani, S.¹ Marcaurelle, L.A.²

5
- 79953777824
- E. Mersault M.L. Peterson J. Med. Chem. 54 2011 1961 2004
- (2011) J. Med. Chem , vol.54 , pp. 1961-2004
- Mersault, E.¹ Peterson, M.L.²

6
- 0034461768
- C.A. Lipinski J. Pharmacol. Toxicol. Methods 44 2000 235 249
- (2000) J. Pharmacol. Toxicol. Methods , vol.44 , pp. 235-249
- Lipinski, C.A.¹

7
- 84939922433
- 45 Nov 15 2012
- J. Kotz SciBx 5 45 Nov 15, 2012
- (2012) SciBx , vol.5
- Kotz, J.¹

8
- 3142685154
- D. Lipovsek A. Pluckthun J. Immunol. Methods 290 2004 51 67
- (2004) J. Immunol. Methods , vol.290 , pp. 51-67
- Lipovsek, D.¹ Pluckthun, A.²

9
- 84889102141
- M. Hamzeh-Mivehroud A.A. Alizadeh M.B. Morris W. Bret Church S. Dastmalchi Drug Discov. Today 18 2013 1144 1157
- (2013) Drug Discov. Today , vol.18 , pp. 1144-1157
- Hamzeh-Mivehroud, M.¹ Alizadeh, A.A.² Morris, M.B.³ Bret Church, W.⁴ Dastmalchi, S.⁵

10
- 26844495780
- S.W. Millward T.T. Takahashi R.W. Roberts J. Am. Chem. Soc. 125 2005 14142 14143
- (2005) J. Am. Chem. Soc , vol.125 , pp. 14142-14143
- Millward, S.W.¹ Takahashi, T.T.² Roberts, R.W.³

11
- 84939922434
- EP03075597.9/P62686EP00
- P. Timerman, J. Beld. W.C. Pujik, J.W. Slootstra, R.H. Meloen, EP03075597.9/P62686EP00.
- Timerman, P.¹ Beld, J.² Pujik, W.C.³ Slootstra, J.W.⁴ Meloen, R.H.⁵

12
- 21044441799
- P. Timmerman J. Beld W.C. Pujik R.H. Meloen ChemBioChem 6 2005 821 824
- (2005) ChemBioChem , vol.6 , pp. 821-824
- Timmerman, P.¹ Beld, J.² Pujik, W.C.³ Meloen, R.H.⁴

13
- 33744911100
- F.P. Seebeck J.W. Szostak J. Am. Chem. Soc. 128 2008 7150 7151
- (2008) J. Am. Chem. Soc , vol.128 , pp. 7150-7151
- Seebeck, F.P.¹ Szostak, J.W.²

14
- 67650305952
- C. Heinis T. Rutherford S. Freund G. Winter Nat. Chem. Biol. 5 2009 502 507
- (2009) Nat. Chem. Biol , vol.5 , pp. 502-507
- Heinis, C.¹ Rutherford, T.² Freund, S.³ Winter, G.⁴

15
- 0033598747
- C.P. Scott E. Abel-Santos M. Wall D.C. Wahnon S.J. Benkovic Proc. Natl. Acad. Sci. 96 1999 13638 13643
- (1999) Proc. Natl. Acad. Sci , vol.96 , pp. 13638-13643
- Scott, C.P.¹ Abel-Santos, E.² Wall, M.³ Wahnon, D.C.⁴ Benkovic, S.J.⁵

16
- 69249124948
- J.A. Kritzer S. Hamamichi J.M. McCaffery S. Santagata T.A. Naumann K.A. Caldwell G.A. Caldwell S. Lindquist Nat. Chem. Biol. 5 2009 655 663
- (2009) Nat. Chem. Biol , vol.5 , pp. 655-663
- Kritzer, J.A.¹ Hamamichi, S.² McCaffery, J.M.³ Santagata, S.⁴ Naumann, T.A.⁵ Caldwell, K.A.⁶ Caldwell, G.A.⁷ Lindquist, S.⁸

17
- 84884283311
- B. Santoso S. Lam B.W. Murray G. Chen Bioorg. Med. Chem. Lett. 23 2013 5680 5683
- (2013) Bioorg. Med. Chem. Lett , vol.23 , pp. 5680-5683
- Santoso, B.¹ Lam, S.² Murray, B.W.³ Chen, G.⁴

18
- 0034177836
- M.A. Dwyer W. Lu J.J. Dwyer A.A. Kossiakoff Chem. Biol. 7 2000 263 274
- (2000) Chem. Biol , vol.7 , pp. 263-274
- Dwyer, M.A.¹ Lu, W.² Dwyer, J.J.³ Kossiakoff, A.A.⁴

19
- 84859627442
- C.J. Hipolito H. Suga Curr. Opin. Chem. Biol. 16 2012 196 203
- (2012) Curr. Opin. Chem. Biol , vol.16 , pp. 196-203
- Hipolito, C.J.¹ Suga, H.²

20
- 84939885852
- K. Josephson, A. Ricardo, J.W. Szostak, Drug Discov. Today doi:10.1016/j.drudis.2013.10.011.
- Drug Discov. Today
- Josephson, K.¹ Ricardo, A.² Szostak, J.W.³

21
- 84876512939
- J.M. Smith J.R. Frost R. Fasan J. Org. Chem. 78 2013 3525 3531
- (2013) J. Org. Chem , vol.78 , pp. 3525-3531
- Smith, J.M.¹ Frost, J.R.² Fasan, R.³

22
- 84896691914
- W.L. Matochko S. Cory Li S.K. Tang R. Derda Nucleic Acid Res. 42 2014 1784 1798
- (2014) Nucleic Acid Res , vol.42 , pp. 1784-1798
- Matochko, W.L.¹ Cory Li, S.² Tang, S.K.³ Derda, R.⁴

23
- 84868344832
- W.L. Matochko K. Chu B. Jin S.W. Lee G.M. Whitesides R. Derda Methods 58 2012 47 55
- (2012) Methods , vol.58 , pp. 47-55
- Matochko, W.L.¹ Chu, K.² Jin, B.³ Lee, S.W.⁴ Whitesides, G.M.⁵ Derda, R.⁶

24
- 84892163643
- F. Giordanetto J. Kihlberg J. Med. Chem. 57 2013 278 295
- (2013) J. Med. Chem , vol.57 , pp. 278-295
- Giordanetto, F.¹ Kihlberg, J.²

25
- 34249736864
- P. Grieco M. Cai G. Han D. Trivdedi P. Campiglia E. Novellino V.J. Hruby Peptides 28 2007 1191 1196
- (2007) Peptides , vol.28 , pp. 1191-1196
- Grieco, P.¹ Cai, M.² Han, G.³ Trivdedi, D.⁴ Campiglia, P.⁵ Novellino, E.⁶ Hruby, V.J.⁷

26
- 42949175115
- L.P. Miranda K.A. Winters C.V. Gegg A. Patel J. Aral J. Long J. Zhang S. Diamond M. Guido S. Stanislaus M. Ma H. Li M.J. Rose L. Poppe M.M. Veniant J. Med. Chem. 51 2008 2758 2765
- (2008) J. Med. Chem , vol.51 , pp. 2758-2765
- Miranda, L.P.¹ Winters, K.A.² Gegg, C.V.³ Patel, A.⁴ Aral, J.⁵ Long, J.⁶ Zhang, J.⁷ Diamond, S.⁸ Guido, M.⁹ Stanislaus, S.¹⁰ Ma, M.¹¹ Li, H.¹² Rose, M.J.¹³ Poppe, L.¹⁴ Veniant, M.M.¹⁵

27
- 80053016932
- M. Dong J.A. Te X. Xu J. Wang D.I. Pinon L. Storjohann A.J. Bordner L.J. Miller Biochemistry 50 2011 8181 8192
- (2011) Biochemistry , vol.50 , pp. 8181-8192
- Dong, M.¹ Te, J.A.² Xu, X.³ Wang, J.⁴ Pinon, D.I.⁵ Storjohann, L.⁶ Bordner, A.J.⁷ Miller, L.J.⁸

28
- 78649901086
- R.H. Harrison G. Ruiz-Gomez T.A. Hill S.Y. Chow N.E. Shepherd R.J. Lohman G. Abbenante H.N. Hoang D.P. Fairlie J. Med. Chem. 53 2010 8400 8408
- (2010) J. Med. Chem , vol.53 , pp. 8400-8408
- Harrison, R.H.¹ Ruiz-Gomez, G.² Hill, T.A.³ Chow, S.Y.⁴ Shepherd, N.E.⁵ Lohman, R.J.⁶ Abbenante, G.⁷ Hoang, H.N.⁸ Fairlie, D.P.⁹

29
- 77955369875
- R.H. Harrison N.E. Shepherd H.N. Hoang G. Ruiz-Gomez T.A. Hill R.W. Driver V.S. Desai P.R. Young G. Abbenante D.P. Fairlie Proc. Natl. Acad. Sci. 107 2010 11686 11691
- (2010) Proc. Natl. Acad. Sci , vol.107 , pp. 11686-11691
- Harrison, R.H.¹ Shepherd, N.E.² Hoang, H.N.³ Ruiz-Gomez, G.⁴ Hill, T.A.⁵ Driver, R.W.⁶ Desai, V.S.⁷ Young, P.R.⁸ Abbenante, G.⁹ Fairlie, D.P.¹⁰

30
- 70349218113
- W.J. Fang Y. Cui T.F. Murray J.V. Aldrich J. Med. Chem. 52 2009 5619 5625
- (2009) J. Med. Chem , vol.52 , pp. 5619-5625
- Fang, W.J.¹ Cui, Y.² Murray, T.F.³ Aldrich, J.V.⁴

31
- 33746052447
- D. Wang K. Chen J.L. Kulp P.S. Arora J. Am. Chem. Soc. 128 2006 9248 9256
- (2006) J. Am. Chem. Soc , vol.128 , pp. 9248-9256
- Wang, D.¹ Chen, K.² Kulp, J.L.³ Arora, P.S.⁴

32
- 57549092075
- L.K. Henchey A.L. Jochim P.S. Arora Curr. Opin. Chem. Biol. 12 2008 692 697
- (2008) Curr. Opin. Chem. Biol , vol.12 , pp. 692-697
- Henchey, L.K.¹ Jochim, A.L.² Arora, P.S.³

33
- 78049450009
- D.A. Guarracino B.N. Bullock P.S. Arora Biopolymers 95 1 2011 1 7
- (2011) Biopolymers , vol.95 , Issue.1 , pp. 1-7
- Guarracino, D.A.¹ Bullock, B.N.² Arora, P.S.³

34
- 84863121468
- S.A. Kawamoto A. Coleska X. Ran H. Yi C.-Y. Yang S. Wang J. Med. Chem. 55 2012 1137 1146
- (2012) J. Med. Chem , vol.55 , pp. 1137-1146
- Kawamoto, S.A.¹ Coleska, A.² Ran, X.³ Yi, H.⁴ Yang, C.-Y.⁵ Wang, S.⁶

35
- 84871019068
- T.L. Aboye H. Ha S. Majumder F. Christ Z. Debyser A. Shekhtman N. Neamati J.A. Camarero J. Med. Chem. 55 2012 10729 10734
- (2012) J. Med. Chem , vol.55 , pp. 10729-10734
- Aboye, T.L.¹ Ha, H.² Majumder, S.³ Christ, F.⁴ Debyser, Z.⁵ Shekhtman, A.⁶ Neamati, N.⁷ Camarero, J.A.⁸

36
- 84891565884
- R. Konterman Wiley-VCH Verlag GmbH & Co Weinheim
- R. Konterman Therapeutic Proteins: Strategies to Modulate Their Plasma Half-lives 2012 Wiley-VCH Verlag GmbH & Co Weinheim
- (2012) Therapeutic Proteins: Strategies to Modulate Their Plasma Half-lives

37
- 84891568046
- S. Schmidt John Wiley & Sons
- S. Schmidt Fusion Protein Technologies for Biopharmaceuticals: Applications and Challenges 2013 John Wiley & Sons
- (2013) Fusion Protein Technologies for Biopharmaceuticals: Applications and Challenges

38
- 84878782419
- C. Bechara S. Sagan FEBS Lett. 587 2013 1693 1702
- (2013) FEBS Lett , vol.587 , pp. 1693-1702
- Bechara, C.¹ Sagan, S.²

39
- 4444291734
- L.D. Walensky A.L. Kung I. Escher T.J. Malia B. Barbuto R.D. Wright G. Wagner G.L. Verdine S.J. Korsmeyer Science 305 2004 1466 1470
- (2004) Science , vol.305 , pp. 1466-1470
- Walensky, L.D.¹ Kung, A.L.² Escher, I.³ Malia, T.J.⁴ Barbuto, B.⁵ Wright, R.D.⁶ Wagner, G.⁷ Verdine, G.L.⁸ Korsmeyer, S.J.⁹

40
- 84874027448
- T. Okamoto K. Zobel A. Fedorova C. Quan H. Yang W.J. Fairbrother D.C.S. Huang B.J. Smith K. Deshayes P.E. Czabotor ACS Chem. Biol. 8 2013 297 302
- (2013) ACS Chem. Biol , vol.8 , pp. 297-302
- Okamoto, T.¹ Zobel, K.² Fedorova, A.³ Quan, C.⁴ Yang, H.⁵ Fairbrother, W.J.⁶ Huang, D.C.S.⁷ Smith, B.J.⁸ Deshayes, K.⁹ Czabotor, P.E.¹⁰

41
- 84939922435
- L.D. Walensky G.H. Bird J. Med. Chem. 2014
- (2014) J. Med. Chem
- Walensky, L.D.¹ Bird, G.H.²

42
- 84875138812
- J.E. Bock J. Gavenonis J.A. Kritzer ACS Chem. Biol. 8 2013 488 499
- (2013) ACS Chem. Biol , vol.8 , pp. 488-499
- Bock, J.E.¹ Gavenonis, J.² Kritzer, J.A.³

43
- 41949086504
- E. Biron J. Chatterjee O. Ovadia D. Langenegger J. Brueggen D. Hoyer H.A. Schmid R. Jelinek C. Gilon A. Hoffman H. Kessler Angew. Chem. Int. Ed. Engl. 47 2008 2595 2599
- (2008) Ange W. Chem. Int. Ed. Engl , vol.47 , pp. 2595-2599
- Biron, E.¹ Chatterjee, J.² Ovadia, O.³ Langenegger, D.⁴ Brueggen, J.⁵ Hoyer, D.⁶ Schmid, H.A.⁷ Jelinek, R.⁸ Gilon, C.⁹ Hoffman, A.¹⁰ Kessler, H.¹¹

44
- 84864182405
- J.G. Beck J. Chatterjee B. Laufer M.U. Kiran A.O. Frank S. Neubauer O. Ovadia S. Greenberg C. Gilon A. Hoffman H. Kessler J. Am. Chem. Soc. 134 2012 12125 12133
- (2012) J. Am. Chem. Soc , vol.134 , pp. 12125-12133
- Beck, J.G.¹ Chatterjee, J.² Laufer, B.³ Kiran, M.U.⁴ Frank, A.O.⁵ Neubauer, S.⁶ Ovadia, O.⁷ Greenberg, S.⁸ Gilon, C.⁹ Hoffman, A.¹⁰ Kessler, H.¹¹

45
- 84867025688
- A.C. Rand S.S. Leung H. Eng C.J. Rotter R. Sharma A.S. Kalgutkar Y. Zhang M.V. Varma K.A. Farley B. Khunte C. Limberakis D.A. Price S. Liras A.M. Mathiowetz M.P. Jacobson R.S. Lokey MedChemComm 3 2012 1282 1289
- (2012) MedChemComm , vol.3 , pp. 1282-1289
- Rand, A.C.¹ Leung, S.S.² Eng, H.³ Rotter, C.J.⁴ Sharma, R.⁵ Kalgutkar, A.S.⁶ Zhang, Y.⁷ Varma, M.V.⁸ Farley, K.A.⁹ Khunte, B.¹⁰ Limberakis, C.¹¹ Price, D.A.¹² Liras, S.¹³ Mathiowetz, A.M.¹⁴ Jacobson, M.P.¹⁵ Lokey, R.S.¹⁶

46
- 34547868470
- L.A. Harris M.D. Crowell Curr. Opin. Mol. Ther. 9 2007 403 410
- (2007) Curr. Opin. Mol. Ther , vol.9 , pp. 403-410
- Harris, L.A.¹ Crowell, M.D.²

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.