Design of triazole-stapled BCL9 α-helical peptides to target the β-catenin/B-cell CLL/lymphoma 9 (BCL9) protein-protein interaction

Journal of Medicinal Chemistry

Volumn 55, Issue 3, 2012, Pages 1137-1146

  Kawamoto, Steven A ^a   Coleska, Adriana ^a   Ran, Xu ^a   Yi, Han ^a   Yang, Chao Yie ^a   Wang, Shaomeng ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYNYL GROUP; B CELL LYMPHOMA 9 PROTEIN; BETA CATENIN; TRANSCRIPTION FACTOR; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO ACID SYNTHESIS; ARTICLE; B CELL LYMPHOMA; BINDING AFFINITY; CELL MEMBRANE PERMEABILITY; CYCLOADDITION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; REACTION OPTIMIZATION;

ALKYNES; AZIDES; BETA CATENIN; CELL LINE, TUMOR; CIRCULAR DICHROISM; CRYSTALLOGRAPHY, X-RAY; CULTURE MEDIA; HUMANS; MODELS, MOLECULAR; NEOPLASM PROTEINS; OLIGOPEPTIDES; PEPTIDE HYDROLASES; PROTEIN INTERACTION MAPS; PROTEIN STRUCTURE, SECONDARY; SOLID-PHASE SYNTHESIS TECHNIQUES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZOLES;

EID: 84863121468     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm201125d     Document Type: Article

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