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Volumn 13, Issue 1, 2014, Pages 50-59

Resolving chromosome-centric human proteome with translating mRNA analysis: A strategic demonstration

Author keywords

C HPP; RNC mRNA, chromosome; RNC seq; strategy; translating mRNA

Indexed keywords

ANTIBODY; MESSENGER RNA; PROTEOME;

EID: 84891798003     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr4007409     Document Type: Article
Times cited : (40)

References (63)
  • 2
    • 84858439862 scopus 로고    scopus 로고
    • Insights into the regulation of protein abundance from proteomic and transcriptomic analyses
    • Vogel, C.; Marcotte, E. M. Insights into the regulation of protein abundance from proteomic and transcriptomic analyses Nat. Rev. Genet. 2012, 13 (4) 227-32
    • (2012) Nat. Rev. Genet. , vol.13 , Issue.4 , pp. 227-232
    • Vogel, C.1    Marcotte, E.M.2
  • 7
    • 84874074018 scopus 로고    scopus 로고
    • The biology/disease-driven human proteome project (B/D-HPP): Enabling protein research for the life sciences community
    • Aebersold, R.; Bader, G. D.; Edwards, A. M.; van Eyk, J. E.; Kussmann, M.; Qin, J.; Omenn, G. S. The biology/disease-driven human proteome project (B/D-HPP): enabling protein research for the life sciences community J. Proteome Res. 2013, 12 (1) 23-7
    • (2013) J. Proteome Res. , vol.12 , Issue.1 , pp. 23-27
    • Aebersold, R.1    Bader, G.D.2    Edwards, A.M.3    Van Eyk, J.E.4    Kussmann, M.5    Qin, J.6    Omenn, G.S.7
  • 12
    • 71149108056 scopus 로고    scopus 로고
    • Correlation of mRNA and protein in complex biological samples
    • Maier, T.; Guell, M.; Serrano, L. Correlation of mRNA and protein in complex biological samples FEBS Lett. 2009, 583 (24) 3966-73
    • (2009) FEBS Lett. , vol.583 , Issue.24 , pp. 3966-3973
    • Maier, T.1    Guell, M.2    Serrano, L.3
  • 15
    • 84877285213 scopus 로고    scopus 로고
    • Translating mRNAs strongly correlate to proteins in a multivariate manner and their translation ratios are phenotype specific
    • Wang, T.; Cui, Y.; Jin, J.; Guo, J.; Wang, G.; Yin, X.; He, Q. Y.; Zhang, G. Translating mRNAs strongly correlate to proteins in a multivariate manner and their translation ratios are phenotype specific Nucleic Acids Res. 2013, 41 (9) 4743-54
    • (2013) Nucleic Acids Res. , vol.41 , Issue.9 , pp. 4743-4754
    • Wang, T.1    Cui, Y.2    Jin, J.3    Guo, J.4    Wang, G.5    Yin, X.6    He, Q.Y.7    Zhang, G.8
  • 17
    • 84879390233 scopus 로고    scopus 로고
    • Identification of missing proteins in the neXtProt database and unregistered phosphopeptides in the PhosphoSitePlus database as part of the Chromosome-centric Human Proteome Project
    • Shiromizu, T.; Adachi, J.; Watanabe, S.; Murakami, T.; Kuga, T.; Muraoka, S.; Tomonaga, T. Identification of missing proteins in the neXtProt database and unregistered phosphopeptides in the PhosphoSitePlus database as part of the Chromosome-centric Human Proteome Project J. Proteome Res. 2013, 12 (6) 2414-21
    • (2013) J. Proteome Res. , vol.12 , Issue.6 , pp. 2414-2421
    • Shiromizu, T.1    Adachi, J.2    Watanabe, S.3    Murakami, T.4    Kuga, T.5    Muraoka, S.6    Tomonaga, T.7
  • 18
    • 84879390436 scopus 로고    scopus 로고
    • Functional annotation of the human chromosome 7 ″missing″ proteins: A bioinformatics approach
    • Ranganathan, S.; Khan, J. M.; Garg, G.; Baker, M. S. Functional annotation of the human chromosome 7 ″missing″ proteins: a bioinformatics approach J. Proteome Res. 2013, 12 (6) 2504-10
    • (2013) J. Proteome Res. , vol.12 , Issue.6 , pp. 2504-2510
    • Ranganathan, S.1    Khan, J.M.2    Garg, G.3    Baker, M.S.4
  • 19
    • 84874085360 scopus 로고    scopus 로고
    • GenomewidePDB, a proteomic database exploring the comprehensive protein parts list and transcriptome landscape in human chromosomes
    • Jeong, S. K.; Lee, H. J.; Na, K.; Cho, J. Y.; Lee, M. J.; Kwon, J. Y.; Kim, H.; Park, Y. M.; Yoo, J. S.; Hancock, W. S.; Paik, Y. K. GenomewidePDB, a proteomic database exploring the comprehensive protein parts list and transcriptome landscape in human chromosomes J. Proteome Res. 2013, 12 (1) 106-11
    • (2013) J. Proteome Res. , vol.12 , Issue.1 , pp. 106-111
    • Jeong, S.K.1    Lee, H.J.2    Na, K.3    Cho, J.Y.4    Lee, M.J.5    Kwon, J.Y.6    Kim, H.7    Park, Y.M.8    Yoo, J.S.9    Hancock, W.S.10    Paik, Y.K.11
  • 22
    • 0019130791 scopus 로고
    • Untranslated mRNA for a chorion protein of Drosophila melanogaster accumulates transiently at the onset of specific gene amplification
    • Thireos, G.; Griffin-Shea, R.; Kafatos, F. C. Untranslated mRNA for a chorion protein of Drosophila melanogaster accumulates transiently at the onset of specific gene amplification Proc. Natl. Acad. Sci. U. S. A. 1980, 77 (10) 5789-93
    • (1980) Proc. Natl. Acad. Sci. U. S. A. , vol.77 , Issue.10 , pp. 5789-5793
    • Thireos, G.1    Griffin-Shea, R.2    Kafatos, F.C.3
  • 23
    • 0022978289 scopus 로고
    • Differential accumulation of ribonucleotide reductase subunits in clam oocytes: The large subunit is stored as a polypeptide, the small subunit as untranslated mRNA
    • Standart, N.; Hunt, T.; Ruderman, J. V. Differential accumulation of ribonucleotide reductase subunits in clam oocytes: the large subunit is stored as a polypeptide, the small subunit as untranslated mRNA J. Cell Biol. 1986, 103 (6 Pt 1) 2129-36
    • (1986) J. Cell Biol. , vol.103 , Issue.6 PART 1 , pp. 2129-2136
    • Standart, N.1    Hunt, T.2    Ruderman, J.V.3
  • 24
    • 0028982138 scopus 로고
    • Growth-dependent translation of IGF-II mRNA by a rapamycin-sensitive pathway
    • Nielsen, F. C.; Ostergaard, L.; Nielsen, J.; Christiansen, J. Growth-dependent translation of IGF-II mRNA by a rapamycin-sensitive pathway Nature 1995, 377 (6547) 358-62
    • (1995) Nature , vol.377 , Issue.6547 , pp. 358-362
    • Nielsen, F.C.1    Ostergaard, L.2    Nielsen, J.3    Christiansen, J.4
  • 25
    • 84883488226 scopus 로고    scopus 로고
    • Effect of a natural mutation in the 5′ untranslated region on the translational control of p53 mRNA
    • Khan, D.; Sharathchandra, A.; Ponnuswamy, A.; Grover, R.; Das, S. Effect of a natural mutation in the 5′ untranslated region on the translational control of p53 mRNA Oncogene 2013, 32 (35) 4148-59
    • (2013) Oncogene , vol.32 , Issue.35 , pp. 4148-4159
    • Khan, D.1    Sharathchandra, A.2    Ponnuswamy, A.3    Grover, R.4    Das, S.5
  • 26
    • 84867043898 scopus 로고    scopus 로고
    • Key issues in the acquisition and analysis of qualitative and quantitative mass spectrometry data for peptide-centric proteomic experiments
    • Thompson, A. J.; Abu, M.; Hanger, D. P. Key issues in the acquisition and analysis of qualitative and quantitative mass spectrometry data for peptide-centric proteomic experiments Amino Acids 2012, 43 (3) 1075-85
    • (2012) Amino Acids , vol.43 , Issue.3 , pp. 1075-1085
    • Thompson, A.J.1    Abu, M.2    Hanger, D.P.3
  • 27
    • 67349196123 scopus 로고    scopus 로고
    • A HUPO test sample study reveals common problems in mass spectrometry-based proteomics
    • Group H.T.S.W.
    • Bell, A. W.; Deutsch, E. W.; Au, C. E.; Kearney, R. E.; Beavis, R.; Sechi, S.; Nilsson, T.; Bergeron, J. J.; Group, H. T. S. W. A HUPO test sample study reveals common problems in mass spectrometry-based proteomics Nat. Methods 2009, 6 (6) 423-30
    • (2009) Nat. Methods , vol.6 , Issue.6 , pp. 423-430
    • Bell, A.W.1    Deutsch, E.W.2    Au, C.E.3    Kearney, R.E.4    Beavis, R.5    Sechi, S.6    Nilsson, T.7    Bergeron, J.J.8
  • 28
    • 58249110387 scopus 로고    scopus 로고
    • States, D. J., Identification of novel alternative splice isoforms of circulating proteins in a mouse model of human pancreatic cancer
    • Menon, R.; Zhang, Q.; Zhang, Y.; Fermin, D.; Bardeesy, N.; DePinho, R. A.; Lu, C.; Hanash, S. M.; Omenn, G. S. States, D. J., Identification of novel alternative splice isoforms of circulating proteins in a mouse model of human pancreatic cancer Cancer Res. 2009, 69 (1) 300-9
    • (2009) Cancer Res. , vol.69 , Issue.1 , pp. 300-309
    • Menon, R.1    Zhang, Q.2    Zhang, Y.3    Fermin, D.4    Bardeesy, N.5    Depinho, R.A.6    Lu, C.7    Hanash, S.M.8    Omenn, G.S.9
  • 29
    • 77951718967 scopus 로고    scopus 로고
    • Proteomic characterization of novel alternative splice variant proteins in human epidermal growth factor receptor 2/neu-induced breast cancers
    • Menon, R.; Omenn, G. S. Proteomic characterization of novel alternative splice variant proteins in human epidermal growth factor receptor 2/neu-induced breast cancers Cancer Res. 2010, 70 (9) 3440-9
    • (2010) Cancer Res. , vol.70 , Issue.9 , pp. 3440-3449
    • Menon, R.1    Omenn, G.S.2
  • 30
    • 82755181925 scopus 로고    scopus 로고
    • Functional implications of structural predictions for alternative splice proteins expressed in Her2/neu-induced breast cancers
    • Menon, R.; Roy, A.; Mukherjee, S.; Belkin, S.; Zhang, Y.; Omenn, G. S. Functional implications of structural predictions for alternative splice proteins expressed in Her2/neu-induced breast cancers J. Proteome Res. 2011, 10 (12) 5503-11
    • (2011) J. Proteome Res. , vol.10 , Issue.12 , pp. 5503-5511
    • Menon, R.1    Roy, A.2    Mukherjee, S.3    Belkin, S.4    Zhang, Y.5    Omenn, G.S.6
  • 31
    • 79952196824 scopus 로고    scopus 로고
    • Identification of alternatively spliced transcripts using a proteomic informatics approach
    • Menon, R.; Omenn, G. S. Identification of alternatively spliced transcripts using a proteomic informatics approach Methods Mol. Biol. 2011, 696, 319-26
    • (2011) Methods Mol. Biol. , vol.696 , pp. 319-326
    • Menon, R.1    Omenn, G.S.2
  • 32
    • 0024077065 scopus 로고
    • Proteins encoded by a complex chloroplast transcription unit are each translated from both monocistronic and polycistronic mRNAs
    • Barkan, A. Proteins encoded by a complex chloroplast transcription unit are each translated from both monocistronic and polycistronic mRNAs EMBO J. 1988, 7 (9) 2637-44
    • (1988) EMBO J. , vol.7 , Issue.9 , pp. 2637-2644
    • Barkan, A.1
  • 33
    • 62049083910 scopus 로고    scopus 로고
    • Transient ribosomal attenuation coordinates protein synthesis and co-translational folding
    • Zhang, G.; Hubalewska, M.; Ignatova, Z. Transient ribosomal attenuation coordinates protein synthesis and co-translational folding Nat. Struct. Mol. Biol. 2009, 16 (3) 274-80
    • (2009) Nat. Struct. Mol. Biol. , vol.16 , Issue.3 , pp. 274-280
    • Zhang, G.1    Hubalewska, M.2    Ignatova, Z.3
  • 34
    • 0031884519 scopus 로고    scopus 로고
    • Translational control: A general mechanism for gene regulation during T cell activation
    • Garcia-Sanz, J. A.; Mikulits, W.; Livingstone, A.; Lefkovits, I.; Mullner, E. W. Translational control: a general mechanism for gene regulation during T cell activation FASEB J 1998, 12 (3) 299-306
    • (1998) FASEB J , vol.12 , Issue.3 , pp. 299-306
    • Garcia-Sanz, J.A.1    Mikulits, W.2    Livingstone, A.3    Lefkovits, I.4    Mullner, E.W.5
  • 35
    • 27144451454 scopus 로고    scopus 로고
    • Homogeneous stalled ribosome nascent chain complexes produced in vivo or in vitro
    • Evans, M. S.; Ugrinov, K. G.; Frese, M. A.; Clark, P. L. Homogeneous stalled ribosome nascent chain complexes produced in vivo or in vitro Nat. Methods 2005, 2 (10) 757-62
    • (2005) Nat. Methods , vol.2 , Issue.10 , pp. 757-762
    • Evans, M.S.1    Ugrinov, K.G.2    Frese, M.A.3    Clark, P.L.4
  • 36
    • 33744551950 scopus 로고    scopus 로고
    • Translation arrest requires two-way communication between a nascent polypeptide and the ribosome
    • Woolhead, C. A.; Johnson, A. E.; Bernstein, H. D. Translation arrest requires two-way communication between a nascent polypeptide and the ribosome Mol. Cell 2006, 22 (5) 587-98
    • (2006) Mol. Cell , vol.22 , Issue.5 , pp. 587-598
    • Woolhead, C.A.1    Johnson, A.E.2    Bernstein, H.D.3
  • 37
    • 62549134121 scopus 로고    scopus 로고
    • Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling
    • Ingolia, N. T.; Ghaemmaghami, S.; Newman, J. R.; Weissman, J. S. Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling Science 2009, 324 (5924) 218-23
    • (2009) Science , vol.324 , Issue.5924 , pp. 218-223
    • Ingolia, N.T.1    Ghaemmaghami, S.2    Newman, J.R.3    Weissman, J.S.4
  • 38
    • 84862227622 scopus 로고    scopus 로고
    • FANSe: An accurate algorithm for quantitative mapping of large scale sequencing reads
    • Zhang, G.; Fedyunin, I.; Kirchner, S.; Xiao, C.; Valleriani, A.; Ignatova, Z. FANSe: an accurate algorithm for quantitative mapping of large scale sequencing reads Nucleic Acids Res. 2012, 40 (11) e83
    • (2012) Nucleic Acids Res. , vol.40 , Issue.11 , pp. 83
    • Zhang, G.1    Fedyunin, I.2    Kirchner, S.3    Xiao, C.4    Valleriani, A.5    Ignatova, Z.6
  • 39
    • 66349083834 scopus 로고    scopus 로고
    • Measuring differential gene expression by short read sequencing: Quantitative comparison to 2-channel gene expression microarrays
    • Bloom, J. S.; Khan, Z.; Kruglyak, L.; Singh, M.; Caudy, A. A. Measuring differential gene expression by short read sequencing: quantitative comparison to 2-channel gene expression microarrays BMC Genomics 2009, 10, 221
    • (2009) BMC Genomics , vol.10 , pp. 221
    • Bloom, J.S.1    Khan, Z.2    Kruglyak, L.3    Singh, M.4    Caudy, A.A.5
  • 41
    • 75249087100 scopus 로고    scopus 로고
    • EdgeR: A Bioconductor package for differential expression analysis of digital gene expression data
    • Robinson, M. D.; McCarthy, D. J.; Smyth, G. K. edgeR: a Bioconductor package for differential expression analysis of digital gene expression data Bioinformatics 2010, 26 (1) 139-40
    • (2010) Bioinformatics , vol.26 , Issue.1 , pp. 139-140
    • Robinson, M.D.1    McCarthy, D.J.2    Smyth, G.K.3
  • 42
    • 79955609350 scopus 로고    scopus 로고
    • Different sequence signatures in the upstream regions of plant and animal tRNA genes shape distinct modes of regulation
    • Zhang, G.; Lukoszek, R.; Mueller-Roeber, B.; Ignatova, Z. Different sequence signatures in the upstream regions of plant and animal tRNA genes shape distinct modes of regulation Nucleic Acids Res. 2011, 39 (8) 3331-9
    • (2011) Nucleic Acids Res. , vol.39 , Issue.8 , pp. 3331-3339
    • Zhang, G.1    Lukoszek, R.2    Mueller-Roeber, B.3    Ignatova, Z.4
  • 43
    • 79960258556 scopus 로고    scopus 로고
    • 100% protein sequence coverage: A modern form of surrealism in proteomics
    • Meyer, B.; Papasotiriou, D. G.; Karas, M. 100% protein sequence coverage: a modern form of surrealism in proteomics Amino Acids 2011, 41 (2) 291-310
    • (2011) Amino Acids , vol.41 , Issue.2 , pp. 291-310
    • Meyer, B.1    Papasotiriou, D.G.2    Karas, M.3
  • 44
    • 84879389449 scopus 로고    scopus 로고
    • High performance computational analysis of large-scale proteome data sets to assess incremental contribution to coverage of the human genome
    • Neuhauser, N.; Nagaraj, N.; McHardy, P.; Zanivan, S.; Scheltema, R.; Cox, J.; Mann, M. High performance computational analysis of large-scale proteome data sets to assess incremental contribution to coverage of the human genome J. Proteome Res. 2013, 12 (6) 2858-68
    • (2013) J. Proteome Res. , vol.12 , Issue.6 , pp. 2858-2868
    • Neuhauser, N.1    Nagaraj, N.2    McHardy, P.3    Zanivan, S.4    Scheltema, R.5    Cox, J.6    Mann, M.7
  • 45
    • 84872685287 scopus 로고    scopus 로고
    • Extensive quantitative remodeling of the proteome between normal colon tissue and adenocarcinoma
    • Wisniewski, J. R.; Ostasiewicz, P.; Dus, K.; Zielinska, D. F.; Gnad, F.; Mann, M. Extensive quantitative remodeling of the proteome between normal colon tissue and adenocarcinoma Mol. Syst. Biol. 2012, 8, 611
    • (2012) Mol. Syst. Biol. , vol.8 , pp. 611
    • Wisniewski, J.R.1    Ostasiewicz, P.2    Dus, K.3    Zielinska, D.F.4    Gnad, F.5    Mann, M.6
  • 48
    • 84869393114 scopus 로고    scopus 로고
    • Toward full peptide sequence coverage by dual fragmentation combining electron-transfer and higher-energy collision dissociation tandem mass spectrometry
    • Frese, C. K.; Altelaar, A. F.; van den Toorn, H.; Nolting, D.; Griep-Raming, J.; Heck, A. J.; Mohammed, S. Toward full peptide sequence coverage by dual fragmentation combining electron-transfer and higher-energy collision dissociation tandem mass spectrometry Anal. Chem. 2012, 84 (22) 9668-73
    • (2012) Anal. Chem. , vol.84 , Issue.22 , pp. 9668-9673
    • Frese, C.K.1    Altelaar, A.F.2    Van Den Toorn, H.3    Nolting, D.4    Griep-Raming, J.5    Heck, A.J.6    Mohammed, S.7
  • 51
    • 33847665108 scopus 로고    scopus 로고
    • Human polymorphism at microRNAs and microRNA target sites
    • Saunders, M. A.; Liang, H.; Li, W. H. Human polymorphism at microRNAs and microRNA target sites Proc. Natl. Acad. Sci. U. S. A. 2007, 104 (9) 3300-5
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , Issue.9 , pp. 3300-3305
    • Saunders, M.A.1    Liang, H.2    Li, W.H.3
  • 52
    • 84891765811 scopus 로고    scopus 로고
    • Distinct splice variants and pathway enrichment in the cell line models of aggressive human breast cancer subtypes
    • Menon, R.; Im, H.; Zhang, E. Y.; Wu, S. L.; Chen, R.; Snyder, M.; Hancock, W. S.; Omenn, G. S., Distinct Splice Variants and Pathway Enrichment in the Cell Line Models of Aggressive Human Breast Cancer Subtypes. J. Proteome Res. 2013.
    • (2013) J. Proteome Res.
    • Menon, R.1    Im, H.2    Zhang, E.Y.3    Wu, S.L.4    Chen, R.5    Snyder, M.6    Hancock, W.S.7    Omenn, G.S.8
  • 54
    • 84875921606 scopus 로고    scopus 로고
    • Substrate specificity of clostridial glucosylating toxins and their function on colonocytes analyzed by proteomics techniques
    • Zeiser, J.; Gerhard, R.; Just, I.; Pich, A., Substrate Specificity of Clostridial Glucosylating Toxins and Their Function on Colonocytes Analyzed by Proteomics Techniques. J. Proteome Res. 2013.
    • (2013) J. Proteome Res.
    • Zeiser, J.1    Gerhard, R.2    Just, I.3    Pich, A.4
  • 55
    • 80051614986 scopus 로고    scopus 로고
    • Impact of clostridial glucosylating toxins on the proteome of colonic cells determined by isotope-coded protein labeling and LC-MALDI
    • Jochim, N.; Gerhard, R.; Just, I.; Pich, A. Impact of clostridial glucosylating toxins on the proteome of colonic cells determined by isotope-coded protein labeling and LC-MALDI Proteome Sci 2011, 9, 48
    • (2011) Proteome Sci , vol.9 , pp. 48
    • Jochim, N.1    Gerhard, R.2    Just, I.3    Pich, A.4
  • 56
    • 34548567439 scopus 로고    scopus 로고
    • Transcriptional profiling of human embryonic stem cells and embryoid bodies identifies HESRG, a novel stem cell gene
    • Zhao, M.; Ren, C.; Yang, H.; Feng, X.; Jiang, X.; Zhu, B.; Zhou, W.; Wang, L.; Zeng, Y.; Yao, K. Transcriptional profiling of human embryonic stem cells and embryoid bodies identifies HESRG, a novel stem cell gene Biochem. Biophys. Res. Commun. 2007, 362 (4) 916-22
    • (2007) Biochem. Biophys. Res. Commun. , vol.362 , Issue.4 , pp. 916-922
    • Zhao, M.1    Ren, C.2    Yang, H.3    Feng, X.4    Jiang, X.5    Zhu, B.6    Zhou, W.7    Wang, L.8    Zeng, Y.9    Yao, K.10
  • 58
    • 84866014702 scopus 로고    scopus 로고
    • Loss-of-heterozygosity on chromosome 19q in early-stage serous ovarian cancer is associated with recurrent disease
    • Skirnisdottir, I.; Mayrhofer, M.; Rydaker, M.; Akerud, H.; Isaksson, A. Loss-of-heterozygosity on chromosome 19q in early-stage serous ovarian cancer is associated with recurrent disease BMC Cancer 2012, 12, 407
    • (2012) BMC Cancer , vol.12 , pp. 407
    • Skirnisdottir, I.1    Mayrhofer, M.2    Rydaker, M.3    Akerud, H.4    Isaksson, A.5
  • 60
    • 0037099620 scopus 로고    scopus 로고
    • Transcript map of the 3.7-Mb D19S112-D19S246 candidate tumor suppressor region on the long arm of chromosome 19
    • Hartmann, C.; Johnk, L.; Kitange, G.; Wu, Y.; Ashworth, L. K.; Jenkins, R. B.; Louis, D. N. Transcript map of the 3.7-Mb D19S112-D19S246 candidate tumor suppressor region on the long arm of chromosome 19 Cancer Res. 2002, 62 (14) 4100-8
    • (2002) Cancer Res. , vol.62 , Issue.14 , pp. 4100-4108
    • Hartmann, C.1    Johnk, L.2    Kitange, G.3    Wu, Y.4    Ashworth, L.K.5    Jenkins, R.B.6    Louis, D.N.7
  • 62
    • 34248671388 scopus 로고    scopus 로고
    • Are chromosomal imbalances important in cancer?
    • Stallings, R. L. Are chromosomal imbalances important in cancer? Trends Genet. 2007, 23 (6) 278-83
    • (2007) Trends Genet. , vol.23 , Issue.6 , pp. 278-283
    • Stallings, R.L.1


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