메뉴 건너뛰기




Volumn 8, Issue 3, 2015, Pages 237-251

Functional and molecular characterisation of EO771.LMB tumours, a new C57BL/6-mouse-derived model of spontaneously metastatic mammary cancer

Author keywords

Breast cancer; Estrogen receptor alpha; Metastasis; Syngeneic preclinical models; Tumour subtyping

Indexed keywords

CALGRANULIN A; CD36 ANTIGEN; CYTOKERATIN 5; CYTOKERATIN 6; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR ALPHA; PARATHYROID HORMONE LIKE HORMONE; PROGESTERONE RECEPTOR; PROTEIN; PROTEIN P53; STROMELYSIN; TAMOXIFEN; THROMBOSPONDIN RECEPTOR; UNCLASSIFIED DRUG; MESSENGER RNA; TUMOR MARKER; TUMOR PROTEIN;

EID: 84929157819     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.017830     Document Type: Article
Times cited : (154)

References (109)
  • 3
    • 45849119823 scopus 로고    scopus 로고
    • S100A8 and S100A9 overexpression is associated with poor pathological parameters in invasive ductal carcinoma of the breast
    • Arai, K., Takano, S., Teratani, T., Ito, Y., Yamada, T. and Nozawa, R. (2008). S100A8 and S100A9 overexpression is associated with poor pathological parameters in invasive ductal carcinoma of the breast. Curr. Cancer Drug Targets 8, 243-252.
    • (2008) Curr. Cancer Drug Targets , vol.8 , pp. 243-252
    • Arai, K.1    Takano, S.2    Teratani, T.3    Ito, Y.4    Yamada, T.5    Nozawa, R.6
  • 4
    • 0026503190 scopus 로고
    • Selective events in the metastatic process defined by analysis of the sequential dissemination of subpopulations of a mouse mammary tumor
    • Aslakson, C. J. and Miller, F. R. (1992). Selective events in the metastatic process defined by analysis of the sequential dissemination of subpopulations of a mouse mammary tumor. Cancer Res. 52, 1399-1405.
    • (1992) Cancer Res , vol.52 , pp. 1399-1405
    • Aslakson, C.J.1    Miller, F.R.2
  • 6
    • 0028346025 scopus 로고
    • Direct evidence linking expression of matrix metalloproteinase 9 (92-kDa gelatinase/collagenase) to the metastatic phenotype in transformed rat embryo cells
    • Bernhard, E. J., Gruber, S. B. and Muschel, R. J. (1994). Direct evidence linking expression of matrix metalloproteinase 9 (92-kDa gelatinase/collagenase) to the metastatic phenotype in transformed rat embryo cells. Proc. Natl. Acad. Sci. USA 91, 4293-4297.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 4293-4297
    • Bernhard, E.J.1    Gruber, S.B.2    Muschel, R.J.3
  • 7
    • 9244227134 scopus 로고    scopus 로고
    • Stromal fibroblasts in cancer initiation and progression
    • Bhowmick, N. A., Neilson, E. G. and Moses, H. L. (2004). Stromal fibroblasts in cancer initiation and progression. Nature 432, 332-337.
    • (2004) Nature , vol.432 , pp. 332-337
    • Bhowmick, N.A.1    Neilson, E.G.2    Moses, H.L.3
  • 8
    • 77953248475 scopus 로고    scopus 로고
    • Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: A collaborative analysis of data for 10,159 cases from 12 studies
    • Blows, F. M., Driver, K. E., Schmidt, M. K., Broeks, A., van Leeuwen, F. E., Wesseling, J., Cheang, M. C., Gelmon, K., Nielsen, T. O., Blomqvist, C. et al. (2010). Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis of data for 10,159 cases from 12 studies. PLoS Med. 7, e1000279.
    • (2010) PLoS Med , vol.7 , pp. e1000279
    • Blows, F.M.1    Driver, K.E.2    Schmidt, M.K.3    Broeks, A.4    Van Leeuwen, F.E.5    Wesseling, J.6    Cheang, M.C.7    Gelmon, K.8    Nielsen, T.O.9    Blomqvist, C.10
  • 11
    • 58249124333 scopus 로고
    • Sustained enhanced growth of carcinoma EO771 in C57 black mice
    • Casey, A. E., Laster, W. R., Jr and Ross, G. L. (1951). Sustained enhanced growth of carcinoma EO771 in C57 black mice. Proc. Soc. Exp. Biol. Med. 77, 358-362.
    • (1951) Proc. Soc. Exp. Biol. Med. , vol.77 , pp. 358-362
    • Casey, A.E.1    Laster, W.R.2    Ross, G.L.3
  • 12
    • 40949121882 scopus 로고    scopus 로고
    • Basal-like breast cancer defined by five biomarkers has superior prognostic value than triple-negative phenotype
    • Cheang, M. C., Voduc, D., Bajdik, C., Leung, S., McKinney, S., Chia, S. K., Perou, C. M. and Nielsen, T. O. (2008). Basal-like breast cancer defined by five biomarkers has superior prognostic value than triple-negative phenotype. Clin. Cancer Res. 14, 1368-1376.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 1368-1376
    • Cheang, M.C.1    Voduc, D.2    Bajdik, C.3    Leung, S.4    McKinney, S.5    Chia, S.K.6    Perou, C.M.7    Nielsen, T.O.8
  • 13
    • 34447307422 scopus 로고    scopus 로고
    • Evidence for a role of tumor-derived laminin-511 in the metastatic progression of breast cancer
    • Chia, J., Kusuma, N., Anderson, R., Parker, B., Bidwell, B., Zamurs, L., Nice, E. and Pouliot, N. (2007). Evidence for a role of tumor-derived laminin-511 in the metastatic progression of breast cancer. Am. J. Pathol. 170, 2135-2148.
    • (2007) Am. J. Pathol. , vol.170 , pp. 2135-2148
    • Chia, J.1    Kusuma, N.2    Anderson, R.3    Parker, B.4    Bidwell, B.5    Zamurs, L.6    Nice, E.7    Pouliot, N.8
  • 14
    • 0030293598 scopus 로고    scopus 로고
    • Matrix metalloproteinases and the development of cancer
    • Coussens, L. M. and Werb, Z. (1996). Matrix metalloproteinases and the development of cancer. Chem. Biol. 3, 895-904.
    • (1996) Chem. Biol. , vol.3 , pp. 895-904
    • Coussens, L.M.1    Werb, Z.2
  • 19
    • 79851471018 scopus 로고    scopus 로고
    • Improved detection of regional melanoma metastasis using 18F-6-fluoro-N-[2-(diethylamino)ethyl] pyridine-3-carboxamide, a melanin-specific PET probe, by perilesional administration
    • Denoyer, D., Potdevin, T., Roselt, P., Neels, O. C., Kirby, L., Greguric, I., Katsifis, A., Dorow, D. S. and Hicks, R. J. (2011). Improved detection of regional melanoma metastasis using 18F-6-fluoro-N-[2-(diethylamino)ethyl] pyridine-3-carboxamide, a melanin-specific PET probe, by perilesional administration. J. Nucl. Med. 52, 115-122.
    • (2011) J. Nucl. Med. , vol.52 , pp. 115-122
    • Denoyer, D.1    Potdevin, T.2    Roselt, P.3    Neels, O.C.4    Kirby, L.5    Greguric, I.6    Katsifis, A.7    Dorow, D.S.8    Hicks, R.J.9
  • 20
    • 84896927538 scopus 로고    scopus 로고
    • Bone-derived soluble factors and laminin-511 cooperate to promote migration, invasion and survival of bone-metastatic breast tumor cells
    • Denoyer, D., Kusuma, N., Burrows, A., Ling, X., Jupp, L., Anderson, R. L. and Pouliot, N. (2014). Bone-derived soluble factors and laminin-511 cooperate to promote migration, invasion and survival of bone-metastatic breast tumor cells. Growth Factors 32, 63-73.
    • (2014) Growth Factors , vol.32 , pp. 63-73
    • Denoyer, D.1    Kusuma, N.2    Burrows, A.3    Ling, X.4    Jupp, L.5    Anderson, R.L.6    Pouliot, N.7
  • 21
    • 81255135837 scopus 로고    scopus 로고
    • Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes
    • DeRose, Y. S., Wang, G., Lin, Y. C., Bernard, P. S., Buys, S. S., Ebbert, M. T., Factor, R., Matsen, C., Milash, B. A., Nelson, E. et al. (2011). Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes. Nat. Med. 17, 1514-1520.
    • (2011) Nat. Med. , vol.17 , pp. 1514-1520
    • DeRose, Y.S.1    Wang, G.2    Lin, Y.C.3    Bernard, P.S.4    Buys, S.S.5    Ebbert, M.T.6    Factor, R.7    Matsen, C.8    Milash, B.A.9    Nelson, E.10
  • 22
  • 26
    • 84861880572 scopus 로고    scopus 로고
    • Strategies for the discovery and development of therapies for metastatic breast cancer
    • Eckhardt, B. L., Francis, P. A., Parker, B. S. and Anderson, R. L. (2012). Strategies for the discovery and development of therapies for metastatic breast cancer. Nat. Rev. Drug Discov. 11, 479-497.
    • (2012) Nat. Rev. Drug Discov. , vol.11 , pp. 479-497
    • Eckhardt, B.L.1    Francis, P.A.2    Parker, B.S.3    Anderson, R.L.4
  • 27
    • 67649208478 scopus 로고    scopus 로고
    • The endogenous Toll-like receptor 4 agonist S100A8/S100A9 (calprotectin) as innate amplifier of infection, autoimmunity, and cancer
    • Ehrchen, J. M., Sunderkötter, C., Foell, D., Vogl, T. and Roth, J. (2009). The endogenous Toll-like receptor 4 agonist S100A8/S100A9 (calprotectin) as innate amplifier of infection, autoimmunity, and cancer. J. Leukoc. Biol. 86, 557-566.
    • (2009) J. Leukoc. Biol. , vol.86 , pp. 557-566
    • Ehrchen, J.M.1    Sunderkötter, C.2    Foell, D.3    Vogl, T.4    Roth, J.5
  • 28
    • 27144492268 scopus 로고    scopus 로고
    • Gene expression analysis reveals a strong signature of an interferon-induced pathway in childhood lymphoblastic leukemia as well as in breast and ovarian cancer
    • Einav, U., Tabach, Y., Getz, G., Yitzhaky, A., Ozbek, U., Amariglio, N., Izraeli, S., Rechavi, G. and Domany, E. (2005). Gene expression analysis reveals a strong signature of an interferon-induced pathway in childhood lymphoblastic leukemia as well as in breast and ovarian cancer. Oncogene 24, 6367-6375.
    • (2005) Oncogene , vol.24 , pp. 6367-6375
    • Einav, U.1    Tabach, Y.2    Getz, G.3    Yitzhaky, A.4    Ozbek, U.5    Amariglio, N.6    Izraeli, S.7    Rechavi, G.8    Domany, E.9
  • 29
    • 0034015880 scopus 로고    scopus 로고
    • Heat-induced alterations in the localization of HSP72 and HSP73 as measured by indirect immunohistochemistry and immunogold electron microscopy
    • Ellis, S., Killender, M. and Anderson, R. L. (2000). Heat-induced alterations in the localization of HSP72 and HSP73 as measured by indirect immunohistochemistry and immunogold electron microscopy. J. Histochem. Cytochem. 48, 321-331.
    • (2000) J. Histochem. Cytochem. , vol.48 , pp. 321-331
    • Ellis, S.1    Killender, M.2    Anderson, R.L.3
  • 30
    • 70349731659 scopus 로고    scopus 로고
    • Parathyroid hormone-related protein protects against mammary tumor emergence and is associated with monocyte infiltration in ductal carcinoma in situ
    • Fleming, N. I., Trivett, M. K., George, J., Slavin, J. L., Murray, W. K., Moseley, J. M., Anderson, R. L. and Thomas, D. M. (2009). Parathyroid hormone-related protein protects against mammary tumor emergence and is associated with monocyte infiltration in ductal carcinoma in situ. Cancer Res. 69, 7473-7479.
    • (2009) Cancer Res. , vol.69 , pp. 7473-7479
    • Fleming, N.I.1    Trivett, M.K.2    George, J.3    Slavin, J.L.4    Murray, W.K.5    Moseley, J.M.6    Anderson, R.L.7    Thomas, D.M.8
  • 32
    • 85118318208 scopus 로고    scopus 로고
    • Novel MMP-3 generated PTHrP peptidespromote osteoblast proliferation: Implications for prostate to bone metastases
    • Chicago, IL: AACR
    • rd Annual Meeting, Vol. 72, pp. 2464. Chicago, IL: AACR.
    • (2012) rd Annual Meeting , vol.72 , pp. 2464
    • Frieling, J.S.1    Pamen, L.A.2    Lynch, C.C.3
  • 33
    • 84879901369 scopus 로고    scopus 로고
    • Comparison of basal-like triple-negative breast cancer defined by morphology, immunohistochemistry and transcriptional profiles
    • Gazinska, P., Grigoriadis, A., Brown, J. P., Millis, R. R., Mera, A., Gillett, C. E., Holmberg, L. H., Tutt, A. N. and Pinder, S. E. (2013). Comparison of basal-like triple-negative breast cancer defined by morphology, immunohistochemistry and transcriptional profiles. Mod. Pathol. 26, 955-966.
    • (2013) Mod. Pathol. , vol.26 , pp. 955-966
    • Gazinska, P.1    Grigoriadis, A.2    Brown, J.P.3    Millis, R.R.4    Mera, A.5    Gillett, C.E.6    Holmberg, L.H.7    Tutt, A.N.8    Pinder, S.E.9
  • 35
    • 84862776961 scopus 로고    scopus 로고
    • Genome-wide association analysis identifies three new breast cancer susceptibility loci
    • Ghoussaini, M., Fletcher, O., Michailidou, K., Turnbull, C., Schmidt, M. K., Dicks, E., Dennis, J., Wang, Q., Humphreys, M. K., Luccarini, C. et al.; Netherlands Collaborative Group on Hereditary Breast and Ovarian Cancer (HEBON); Familial Breast Cancer Study (FBCS); Gene Environment Interaction of Breast Cancer in Germany (GENICA) Network; kConFab Investigators; Australian Ovarian Cancer Study Group (2012). Genome-wide association analysis identifies three new breast cancer susceptibility loci. Nat. Genet. 44, 312-318.
    • (2012) Nat. Genet. , vol.44 , pp. 312-318
    • Ghoussaini, M.1    Fletcher, O.2    Michailidou, K.3    Turnbull, C.4    Schmidt, M.K.5    Dicks, E.6    Dennis, J.7    Wang, Q.8    Humphreys, M.K.9    Luccarini, C.10
  • 36
    • 10144241022 scopus 로고    scopus 로고
    • Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis
    • Guise, T. A., Yin, J. J., Taylor, S. D., Kumagai, Y., Dallas, M., Boyce, B. F., Yoneda, T. and Mundy, G. R. (1996). Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis. J. Clin. Invest. 98, 1544-1549.
    • (1996) J. Clin. Invest. , vol.98 , pp. 1544-1549
    • Guise, T.A.1    Yin, J.J.2    Taylor, S.D.3    Kumagai, Y.4    Dallas, M.5    Boyce, B.F.6    Yoneda, T.7    Mundy, G.R.8
  • 37
  • 38
    • 0026587657 scopus 로고
    • Induction of mammary tumors by expression of polyomavirus middle T oncogene: A transgenic mouse model for metastatic disease
    • Guy, C. T., Cardiff, R. D. and Muller, W. J. (1992a). Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease. Mol. Cell. Biol. 12, 954-961.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 954-961
    • Guy, C.T.1    Cardiff, R.D.2    Muller, W.J.3
  • 39
    • 0026472124 scopus 로고
    • Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease
    • Guy, C. T., Webster, M. A., Schaller, M., Parsons, T. J., Cardiff, R. D. and Muller, W. J. (1992b). Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease. Proc. Natl. Acad. Sci. USA 89, 10578-10582.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 10578-10582
    • Guy, C.T.1    Webster, M.A.2    Schaller, M.3    Parsons, T.J.4    Cardiff, R.D.5    Muller, W.J.6
  • 43
    • 0033725056 scopus 로고    scopus 로고
    • Glycosylation-dependent cell adhesion molecule 1 (GlyCAM 1) is induced by prolactin and suppressed by progesterone in mammary epithelium
    • Hou, Z., Bailey, J. P., Vomachka, A. J., Matsuda, M., Lockefeer, J. A. and Horseman, N. D. (2000). Glycosylation-dependent cell adhesion molecule 1 (GlyCAM 1) is induced by prolactin and suppressed by progesterone in mammary epithelium. Endocrinology 141, 4278-4283.
    • (2000) Endocrinology , vol.141 , pp. 4278-4283
    • Hou, Z.1    Bailey, J.P.2    Vomachka, A.J.3    Matsuda, M.4    Lockefeer, J.A.5    Horseman, N.D.6
  • 45
    • 70350231667 scopus 로고    scopus 로고
    • Pulmonary vascular destabilization in the premetastatic phase facilitates lung metastasis
    • Huang, Y., Song, N., Ding, Y., Yuan, S., Li, X., Cai, H., Shi, H. and Luo, Y. (2009). Pulmonary vascular destabilization in the premetastatic phase facilitates lung metastasis. Cancer Res. 69, 7529-7537.
    • (2009) Cancer Res. , vol.69 , pp. 7529-7537
    • Huang, Y.1    Song, N.2    Ding, Y.3    Yuan, S.4    Li, X.5    Cai, H.6    Shi, H.7    Luo, Y.8
  • 46
    • 84856222545 scopus 로고    scopus 로고
    • Mouse models of cancer: Does the strain matter?
    • Hunter, K. W. (2012). Mouse models of cancer: does the strain matter? Nat. Rev. Cancer 12, 144-149.
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 144-149
    • Hunter, K.W.1
  • 47
    • 34248233109 scopus 로고    scopus 로고
    • Isogenic normal basal and luminal mammary epithelial isolated by a novel method show a differential response to ionizing radiation
    • Huper, G. and Marks, J. R. (2007). Isogenic normal basal and luminal mammary epithelial isolated by a novel method show a differential response to ionizing radiation. Cancer Res. 67, 2990-3001.
    • (2007) Cancer Res. , vol.67 , pp. 2990-3001
    • Huper, G.1    Marks, J.R.2
  • 48
    • 3242763031 scopus 로고    scopus 로고
    • ARHGAP8 is a novel member of the RHOGAP family related to ARHGAP1/CDC42GAP/p50RHOGAP: Mutation and expression analyses in colorectal and breast cancers
    • Johnstone, C. N., Castellví-Bel, S., Chang, L. M., Bessa, X., Nakagawa, H., Harada, H., Sung, R. K., Piqué, J. M., Castells, A. and Rustgi, A. K. (2004). ARHGAP8 is a novel member of the RHOGAP family related to ARHGAP1/CDC42GAP/p50RHOGAP: mutation and expression analyses in colorectal and breast cancers. Gene 336, 59-71.
    • (2004) Gene , vol.336 , pp. 59-71
    • Johnstone, C.N.1    Castellví-Bel, S.2    Chang, L.M.3    Bessa, X.4    Nakagawa, H.5    Harada, H.6    Sung, R.K.7    Piqué, J.M.8    Castells, A.9    Rustgi, A.K.10
  • 49
    • 78049348480 scopus 로고    scopus 로고
    • Multi-cancer computational analysis reveals invasion-associated variant of desmoplastic reaction involving INHBA, THBS2 and COL11A1
    • Kim, H., Watkinson, J., Varadan, V. and Anastassiou, D. (2010). Multi-cancer computational analysis reveals invasion-associated variant of desmoplastic reaction involving INHBA, THBS2 and COL11A1. BMC Med. Genomics 3, 51.
    • (2010) BMC Med. Genomics , vol.3 , pp. 51
    • Kim, H.1    Watkinson, J.2    Varadan, V.3    Anastassiou, D.4
  • 50
    • 79959706654 scopus 로고    scopus 로고
    • CD36-mediated activation of endothelial cell apoptosis by an N-terminal recombinant fragment of thrombospondin-2 inhibits breast cancer growth and metastasis in vivo
    • Koch, M., Hussein, F., Woeste, A., Gründker, C., Frontzek, K., Emons, G. and Hawighorst, T. (2011). CD36-mediated activation of endothelial cell apoptosis by an N-terminal recombinant fragment of thrombospondin-2 inhibits breast cancer growth and metastasis in vivo. Breast Cancer Res. Treat. 128, 337-346.
    • (2011) Breast Cancer Res. Treat. , vol.128 , pp. 337-346
    • Koch, M.1    Hussein, F.2    Woeste, A.3    Gründker, C.4    Frontzek, K.5    Emons, G.6    Hawighorst, T.7
  • 51
    • 80053923045 scopus 로고    scopus 로고
    • Parathyroid hormone related protein (PTHrP) in tumor progression
    • Kremer, R., Li, J., Camirand, A. and Karaplis, A. C. (2011). Parathyroid hormone related protein (PTHrP) in tumor progression. Adv. Exp. Med. Biol. 720, 145-160.
    • (2011) Adv. Exp. Med. Biol. , vol.720 , pp. 145-160
    • Kremer, R.1    Li, J.2    Camirand, A.3    Karaplis, A.C.4
  • 53
    • 82355175803 scopus 로고    scopus 로고
    • Laminin alpha5-derived peptides modulate the properties of metastatic breast tumour cells
    • Kusuma, N., Anderson, R. L. and Pouliot, N. (2011). Laminin alpha5-derived peptides modulate the properties of metastatic breast tumour cells. Clin. Exp. Metastasis 28, 909-921.
    • (2011) Clin. Exp. Metastasis , vol.28 , pp. 909-921
    • Kusuma, N.1    Anderson, R.L.2    Pouliot, N.3
  • 55
    • 79960015997 scopus 로고    scopus 로고
    • Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
    • Lehmann, B. D., Bauer, J. A., Chen, X., Sanders, M. E., Chakravarthy, A. B., Shyr, Y. and Pietenpol, J. A. (2011). Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies. J. Clin. Invest. 121, 2750-2767.
    • (2011) J. Clin. Invest. , vol.121 , pp. 2750-2767
    • Lehmann, B.D.1    Bauer, J.A.2    Chen, X.3    Sanders, M.E.4    Chakravarthy, A.B.5    Shyr, Y.6    Pietenpol, J.A.7
  • 57
    • 84055191098 scopus 로고    scopus 로고
    • PTHrP drives breast tumor initiation, progression, and metastasis in mice and is a potential therapy target
    • Li, J., Karaplis, A. C., Huang, D. C., Siegel, P. M., Camirand, A., Yang, X. F., Muller, W. J. and Kremer, R. (2011). PTHrP drives breast tumor initiation, progression, and metastasis in mice and is a potential therapy target. J. Clin. Invest. 121, 4655-4669.
    • (2011) J. Clin. Invest. , vol.121 , pp. 4655-4669
    • Li, J.1    Karaplis, A.C.2    Huang, D.C.3    Siegel, P.M.4    Camirand, A.5    Yang, X.F.6    Muller, W.J.7    Kremer, R.8
  • 58
    • 0031823908 scopus 로고    scopus 로고
    • Identification of inbred mouse strains harboring genetic modifiers of mammary tumor age of onset and metastatic progression
    • Lifsted, T., Le Voyer, T., Williams, M., Muller, W., Klein-Szanto, A., Buetow, K. H. and Hunter, K. W. (1998). Identification of inbred mouse strains harboring genetic modifiers of mammary tumor age of onset and metastatic progression. Int. J. Cancer 77, 640-644.
    • (1998) Int. J. Cancer , vol.77 , pp. 640-644
    • Lifsted, T.1    Le Voyer, T.2    Williams, M.3    Muller, W.4    Klein-Szanto, A.5    Buetow, K.H.6    Hunter, K.W.7
  • 59
    • 0036793825 scopus 로고    scopus 로고
    • Coexpression of parathyroid hormone related protein and its receptor in early breast cancer predicts poor patient survival
    • Linforth, R., Anderson, N., Hoey, R., Nolan, T., Downey, S., Brady, G., Ashcroft, L. and Bundred, N. (2002). Coexpression of parathyroid hormone related protein and its receptor in early breast cancer predicts poor patient survival. Clin. Cancer Res. 8, 3172-3177.
    • (2002) Clin. Cancer Res. , vol.8 , pp. 3172-3177
    • Linforth, R.1    Anderson, N.2    Hoey, R.3    Nolan, T.4    Downey, S.5    Brady, G.6    Ashcroft, L.7    Bundred, N.8
  • 60
    • 0032134034 scopus 로고    scopus 로고
    • The primary structure of caprine PP3: Amino acid sequence, phosphorylation, and glycosylation of component PP3 from the proteose-peptone fraction of caprine milk
    • Lister, I. M., Rasmussen, L. K., Johnsen, L. B., Møller, L., Petersen, T. E. and Sørensen, E. S. (1998). The primary structure of caprine PP3: amino acid sequence, phosphorylation, and glycosylation of component PP3 from the proteose-peptone fraction of caprine milk. J. Dairy Sci. 81, 2111-2115.
    • (1998) J. Dairy Sci. , vol.81 , pp. 2111-2115
    • Lister, I.M.1    Rasmussen, L.K.2    Johnsen, L.B.3    Møller, L.4    Petersen, T.E.5    Sørensen, E.S.6
  • 61
    • 0031426654 scopus 로고    scopus 로고
    • Matrix metalloproteinase stromelysin-1 triggers a cascade of molecular alterations that leads to stable epithelial-to-mesenchymal conversion and a premalignant phenotype in mammary epithelial cells
    • Lochter, A., Galosy, S., Muschler, J., Freedman, N., Werb, Z. and Bissell, M. J. (1997a). Matrix metalloproteinase stromelysin-1 triggers a cascade of molecular alterations that leads to stable epithelial-to-mesenchymal conversion and a premalignant phenotype in mammary epithelial cells. J. Cell Biol. 139, 1861-1872.
    • (1997) J. Cell Biol. , vol.139 , pp. 1861-1872
    • Lochter, A.1    Galosy, S.2    Muschler, J.3    Freedman, N.4    Werb, Z.5    Bissell, M.J.6
  • 62
    • 0031040331 scopus 로고    scopus 로고
    • Misregulation of stromelysin-1 expression in mouse mammary tumor cells accompanies acquisition of stromelysin-1-dependent invasive properties
    • Lochter, A., Srebrow, A., Sympson, C. J., Terracio, N., Werb, Z. and Bissell, M. J. (1997b). Misregulation of stromelysin-1 expression in mouse mammary tumor cells accompanies acquisition of stromelysin-1-dependent invasive properties. J. Biol. Chem. 272, 5007-5015.
    • (1997) J. Biol. Chem. , vol.272 , pp. 5007-5015
    • Lochter, A.1    Srebrow, A.2    Sympson, C.J.3    Terracio, N.4    Werb, Z.5    Bissell, M.J.6
  • 63
    • 84861191800 scopus 로고    scopus 로고
    • Building the niche: The role of the S100 proteins in metastatic growth
    • Lukanidin, E. and Sleeman, J. P. (2012). Building the niche: the role of the S100 proteins in metastatic growth. Semin. Cancer Biol. 22, 216-225.
    • (2012) Semin. Cancer Biol. , vol.22 , pp. 216-225
    • Lukanidin, E.1    Sleeman, J.P.2
  • 64
    • 84879833107 scopus 로고    scopus 로고
    • BreastMark: An integrated approach to mining publicly available transcriptomic datasets relating to breast cancer outcome
    • Madden, S. F., Clarke, C., Gaule, P., Aherne, S. T., O'Donovan, N., Clyne, M., Crown, J. and Gallagher, W. M. (2013). BreastMark: an integrated approach to mining publicly available transcriptomic datasets relating to breast cancer outcome. Breast Cancer Res. 15, R52.
    • (2013) Breast Cancer Res. , vol.15 , pp. R52
    • Madden, S.F.1    Clarke, C.2    Gaule, P.3    Aherne, S.T.4    O'Donovan, N.5    Clyne, M.6    Crown, J.7    Gallagher, W.M.8
  • 65
    • 51049100625 scopus 로고    scopus 로고
    • Effect of ablation or inhibition of stromal matrix metalloproteinase-9 on lung metastasis in a breast cancer model is dependent on genetic background
    • Martin, M. D., Carter, K. J., Jean-Philippe, S. R., Chang, M., Mobashery, S., Thiolloy, S., Lynch, C. C., Matrisian, L. M. and Fingleton, B. (2008). Effect of ablation or inhibition of stromal matrix metalloproteinase-9 on lung metastasis in a breast cancer model is dependent on genetic background. Cancer Res. 68, 6251-6259.
    • (2008) Cancer Res. , vol.68 , pp. 6251-6259
    • Martin, M.D.1    Carter, K.J.2    Jean-Philippe, S.R.3    Chang, M.4    Mobashery, S.5    Thiolloy, S.6    Lynch, C.C.7    Matrisian, L.M.8    Fingleton, B.9
  • 68
    • 54249140458 scopus 로고    scopus 로고
    • Global gene expression profiling unveils S100A8/A9 as candidate markers in H-ras-mediated human breast epithelial cell invasion
    • Moon, A., Yong, H. Y., Song, J. I., Cukovic, D., Salagrama, S., Kaplan, D., Putt, D., Kim, H., Dombkowski, A. and Kim, H. R. (2008). Global gene expression profiling unveils S100A8/A9 as candidate markers in H-ras-mediated human breast epithelial cell invasion. Mol. Cancer Res. 6, 1544-1553.
    • (2008) Mol. Cancer Res. , vol.6 , pp. 1544-1553
    • Moon, A.1    Yong, H.Y.2    Song, J.I.3    Cukovic, D.4    Salagrama, S.5    Kaplan, D.6    Putt, D.7    Kim, H.8    Dombkowski, A.9    Kim, H.R.10
  • 69
    • 0023713558 scopus 로고
    • Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene
    • Muller, W. J., Sinn, E., Pattengale, P. K., Wallace, R. and Leder, P. (1988). Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene. Cell 54, 105-115.
    • (1988) Cell , vol.54 , pp. 105-115
    • Muller, W.J.1    Sinn, E.2    Pattengale, P.K.3    Wallace, R.4    Leder, P.5
  • 72
    • 0021986654 scopus 로고
    • Immunohistologic localization of estrogen receptors in breast cancer with monoclonal antibodies. Correlation with biochemistry and clinical endocrine response
    • Pertschuk, L. P., Eisenberg, K. B., Carter, A. C. and Feldman, J. G. (1985). Immunohistologic localization of estrogen receptors in breast cancer with monoclonal antibodies. Correlation with biochemistry and clinical endocrine response. Cancer 55, 1513-1518.
    • (1985) Cancer , vol.55 , pp. 1513-1518
    • Pertschuk, L.P.1    Eisenberg, K.B.2    Carter, A.C.3    Feldman, J.G.4
  • 74
    • 84863726204 scopus 로고    scopus 로고
    • The tumor microenvironment modulates tamoxifen resistance in breast cancer: A role for soluble stromal factors and fibronectin through β1 integrin
    • Pontiggia, O., Sampayo, R., Raffo, D., Motter, A., Xu, R., Bissell, M. J., Joffé, E. B. and Simian, M. (2012). The tumor microenvironment modulates tamoxifen resistance in breast cancer: a role for soluble stromal factors and fibronectin through β1 integrin. Breast Cancer Res. Treat. 133, 459-471.
    • (2012) Breast Cancer Res. Treat. , vol.133 , pp. 459-471
    • Pontiggia, O.1    Sampayo, R.2    Raffo, D.3    Motter, A.4    Xu, R.5    Bissell, M.J.6    Joffé, E.B.7    Simian, M.8
  • 78
    • 0033532205 scopus 로고    scopus 로고
    • Activation of matrix metalloproteinase-9 (MMP-9) via a converging plasmin/stromelysin-1 cascade enhances tumor cell invasion
    • Ramos-DeSimone, N., Hahn-Dantona, E., Sipley, J., Nagase, H., French, D. L. and Quigley, J. P. (1999). Activation of matrix metalloproteinase-9 (MMP-9) via a converging plasmin/stromelysin-1 cascade enhances tumor cell invasion. J. Biol. Chem. 274, 13066-13076.
    • (1999) J. Biol. Chem. , vol.274 , pp. 13066-13076
    • Ramos-DeSimone, N.1    Hahn-Dantona, E.2    Sipley, J.3    Nagase, H.4    French, D.L.5    Quigley, J.P.6
  • 80
    • 0015583407 scopus 로고
    • Cellular radiosensitivity and tumor radiation response in the EMT6 tumor cell system
    • Rockwell, S. and Kallman, R. F. (1973). Cellular radiosensitivity and tumor radiation response in the EMT6 tumor cell system. Radiat. Res. 53, 281-294.
    • (1973) Radiat. Res. , vol.53 , pp. 281-294
    • Rockwell, S.1    Kallman, R.F.2
  • 81
    • 80053393750 scopus 로고    scopus 로고
    • Insight into the heterogeneity of breast cancer through next-generation sequencing
    • Russnes, H. G., Navin, N., Hicks, J. and Borresen-Dale, A. L. (2011). Insight into the heterogeneity of breast cancer through next-generation sequencing. J. Clin. Invest. 121, 3810-3818.
    • (2011) J. Clin. Invest. , vol.121 , pp. 3810-3818
    • Russnes, H.G.1    Navin, N.2    Hicks, J.3    Borresen-Dale, A.L.4
  • 82
    • 0036710458 scopus 로고    scopus 로고
    • Genes involved in breast cancer metastasis to bone
    • Sloan, E. K. and Anderson, R. L. (2002). Genes involved in breast cancer metastasis to bone. Cell. Mol. Life Sci. 59, 1491-1502.
    • (2002) Cell. Mol. Life Sci. , vol.59 , pp. 1491-1502
    • Sloan, E.K.1    Anderson, R.L.2
  • 83
    • 33746513396 scopus 로고    scopus 로고
    • Tumor-specific expression of alphavbeta3 integrin promotes spontaneous metastasis of breast cancer to bone
    • Sloan, E. K., Pouliot, N., Stanley, K. L., Chia, J., Moseley, J. M., Hards, D. K. and Anderson, R. L. (2006). Tumor-specific expression of alphavbeta3 integrin promotes spontaneous metastasis of breast cancer to bone. Breast Cancer Res. 8, R20.
    • (2006) Breast Cancer Res. , vol.8 , pp. R20
    • Sloan, E.K.1    Pouliot, N.2    Stanley, K.L.3    Chia, J.4    Moseley, J.M.5    Hards, D.K.6    Anderson, R.L.7
  • 88
    • 38449121249 scopus 로고    scopus 로고
    • Altered immune function during long-term host-tumor interactions can be modulated to retard autochthonous neoplastic growth
    • Stewart, T. J. and Abrams, S. I. (2007). Altered immune function during long-term host-tumor interactions can be modulated to retard autochthonous neoplastic growth. J. Immunol. 179, 2851-2859.
    • (2007) J. Immunol. , vol.179 , pp. 2851-2859
    • Stewart, T.J.1    Abrams, S.I.2
  • 89
    • 0027293310 scopus 로고
    • Immunohistochemical and biochemical measurement of estrogen and progesterone receptors in primary breast cancer. Correlation of histopathology and prognostic factors
    • Stierer, M., Rosen, H., Weber, R., Hanak, H., Spona, J. and Tüchler, H. (1993). Immunohistochemical and biochemical measurement of estrogen and progesterone receptors in primary breast cancer. Correlation of histopathology and prognostic factors. Ann. Surg. 218, 13-21.
    • (1993) Ann. Surg. , vol.218 , pp. 13-21
    • Stierer, M.1    Rosen, H.2    Weber, R.3    Hanak, H.4    Spona, J.5    Tüchler, H.6
  • 90
    • 0345701523 scopus 로고    scopus 로고
    • Prognostic value of immunocytochemical determination of parathyroid hormone-related peptide expression in cells of mammary ductal carcinoma. Analysis of 7 years of the disease course
    • Surowiak, P., Dziegiel, P., Matkowski, R., Sopel, M., Wojnar, A., Kornafel, J. and Zabel, M. (2003). Prognostic value of immunocytochemical determination of parathyroid hormone-related peptide expression in cells of mammary ductal carcinoma. Analysis of 7 years of the disease course. Virchows Arch. 442, 245-251.
    • (2003) Virchows Arch. , vol.442 , pp. 245-251
    • Surowiak, P.1    Dziegiel, P.2    Matkowski, R.3    Sopel, M.4    Wojnar, A.5    Kornafel, J.6    Zabel, M.7
  • 91
    • 77957262381 scopus 로고    scopus 로고
    • Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes
    • Taube, J. H., Herschkowitz, J. I., Komurov, K., Zhou, A. Y., Gupta, S., Yang, J., Hartwell, K., Onder, T. T., Gupta, P. B., Evans, K. W. et al. (2010). Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes. Proc. Natl. Acad. Sci. USA 107, 15449-15454.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 15449-15454
    • Taube, J.H.1    Herschkowitz, J.I.2    Komurov, K.3    Zhou, A.Y.4    Gupta, S.5    Yang, J.6    Hartwell, K.7    Onder, T.T.8    Gupta, P.B.9    Evans, K.W.10
  • 92
    • 34648829133 scopus 로고    scopus 로고
    • An immune response gene expression module identifies a good prognosis subtype in estrogen receptor negative breast cancer
    • Teschendorff, A. E., Miremadi, A., Pinder, S. E., Ellis, I. O. and Caldas, C. (2007). An immune response gene expression module identifies a good prognosis subtype in estrogen receptor negative breast cancer. Genome Biol. 8, R157.
    • (2007) Genome Biol. , vol.8 , pp. R157
    • Teschendorff, A.E.1    Miremadi, A.2    Pinder, S.E.3    Ellis, I.O.4    Caldas, C.5
  • 93
    • 0034787967 scopus 로고    scopus 로고
    • MMP-9 secretion and MMP-2 activation distinguish invasive and metastatic sublines of a mouse mammary carcinoma system showing epithelial-mesenchymal transition traits
    • Tester, A. M., Ruangpanit, N., Anderson, R. L. and Thompson, E. W. (2000). MMP-9 secretion and MMP-2 activation distinguish invasive and metastatic sublines of a mouse mammary carcinoma system showing epithelial-mesenchymal transition traits. Clin. Exp. Metastasis 18, 553-560.
    • (2000) Clin. Exp. Metastasis , vol.18 , pp. 553-560
    • Tester, A.M.1    Ruangpanit, N.2    Anderson, R.L.3    Thompson, E.W.4
  • 94
    • 84877028141 scopus 로고    scopus 로고
    • Comprehensive molecular portraits of human breast tumours
    • The Cancer Genome Atlas Network (2012). Comprehensive molecular portraits of human breast tumours. Nature 490, 61-70.
    • (2012) Nature , vol.490 , pp. 61-70
  • 95
    • 84861634733 scopus 로고    scopus 로고
    • Physiological levels of Pik3ca(H1047R) mutation in the mouse mammary gland results in ductal hyperplasia and formation of ERα-positive tumors
    • Tikoo, A., Roh, V., Montgomery, K. G., Ivetac, I., Waring, P., Pelzer, R., Hare, L., Shackleton, M., Humbert, P. and Phillips, W. A. (2012). Physiological levels of Pik3ca(H1047R) mutation in the mouse mammary gland results in ductal hyperplasia and formation of ERα-positive tumors. PLoS ONE 7, e36924.
    • (2012) PLoS ONE , vol.7 , pp. e36924
    • Tikoo, A.1    Roh, V.2    Montgomery, K.G.3    Ivetac, I.4    Waring, P.5    Pelzer, R.6    Hare, L.7    Shackleton, M.8    Humbert, P.9    Phillips, W.A.10
  • 96
    • 77950849807 scopus 로고    scopus 로고
    • Y-box binding protein-1 induces the expression of CD44 and CD49f leading to enhanced selfrenewal, mammosphere growth, and drug resistance
    • To, K., Fotovati, A., Reipas, K. M., Law, J. H., Hu, K., Wang, J., Astanehe, A., Davies, A. H., Lee, L., Stratford, A. L. et al. (2010). Y-box binding protein-1 induces the expression of CD44 and CD49f leading to enhanced selfrenewal, mammosphere growth, and drug resistance. Cancer Res. 70, 2840-2851.
    • (2010) Cancer Res. , vol.70 , pp. 2840-2851
    • To, K.1    Fotovati, A.2    Reipas, K.M.3    Law, J.H.4    Hu, K.5    Wang, J.6    Astanehe, A.7    Davies, A.H.8    Lee, L.9    Stratford, A.L.10
  • 97
    • 0024354304 scopus 로고
    • Determination of subcutaneous tumor size in athymic (nude) mice
    • Tomayko, M. M. and Reynolds, C. P. (1989). Determination of subcutaneous tumor size in athymic (nude) mice. Cancer Chemother. Pharmacol. 24, 148-154.
    • (1989) Cancer Chemother. Pharmacol. , vol.24 , pp. 148-154
    • Tomayko, M.M.1    Reynolds, C.P.2
  • 99
    • 34347230544 scopus 로고    scopus 로고
    • Sulforhodamine B colorimetric assay for cytotoxicity screening
    • Vichai, V. and Kirtikara, K. (2006). Sulforhodamine B colorimetric assay for cytotoxicity screening. Nat. Protoc. 1, 1112-1116.
    • (2006) Nat. Protoc. , vol.1 , pp. 1112-1116
    • Vichai, V.1    Kirtikara, K.2
  • 102
    • 0032081560 scopus 로고    scopus 로고
    • p53 and protein kinase C independent induction of growth arrest and apoptosis by bryostatin 1 in a highly metastatic mammary epithelial cell line: In vitro versus in vivo activity
    • Wang, H., Mohammad, R. M., Werdell, J. and Shekhar, P. V. (1998). p53 and protein kinase C independent induction of growth arrest and apoptosis by bryostatin 1 in a highly metastatic mammary epithelial cell line: in vitro versus in vivo activity. Int. J. Mol. Med. 1, 915-923.
    • (1998) Int. J. Mol. Med. , vol.1 , pp. 915-923
    • Wang, H.1    Mohammad, R.M.2    Werdell, J.3    Shekhar, P.V.4
  • 105
    • 0026578054 scopus 로고
    • P53 in tumour pathology: Can we trust immunocytochemistry?
    • Wynford-Thomas, D. (1992). P53 in tumour pathology: can we trust immunocytochemistry? J. Pathol. 166, 329-330.
    • (1992) J. Pathol. , vol.166 , pp. 329-330
    • Wynford-Thomas, D.1
  • 106
    • 80052414827 scopus 로고    scopus 로고
    • Immunohistochemical staining patterns of p53 can serve as a surrogate marker for TP53 mutations in ovarian carcinoma: An immunohistochemical and nucleotide sequencing analysis
    • Yemelyanova, A., Vang, R., Kshirsagar, M., Lu, D., Marks, M. A., Shih, IM. and Kurman, R. J. (2011). Immunohistochemical staining patterns of p53 can serve as a surrogate marker for TP53 mutations in ovarian carcinoma: an immunohistochemical and nucleotide sequencing analysis. Mod. Pathol. 24, 1248-1253.
    • (2011) Mod. Pathol. , vol.24 , pp. 1248-1253
    • Yemelyanova, A.1    Vang, R.2    Kshirsagar, M.3    Lu, D.4    Marks, M.A.5    Shih, I.M.6    Kurman, R.J.7
  • 107
    • 65449166841 scopus 로고    scopus 로고
    • Differential sensitivity of breast cancer and melanoma cells to proteasome inhibitor Velcade
    • Yerlikaya, A. and Erin, N. (2008). Differential sensitivity of breast cancer and melanoma cells to proteasome inhibitor Velcade. Int. J. Mol. Med. 22, 817-823.
    • (2008) Int. J. Mol. Med. , vol.22 , pp. 817-823
    • Yerlikaya, A.1    Erin, N.2
  • 109
    • 0027650575 scopus 로고
    • Adhesion molecules in tumor metastasis
    • Zetter, B. R. (1993). Adhesion molecules in tumor metastasis. Semin. Cancer Biol. 4, 219-229.
    • (1993) Semin. Cancer Biol. , vol.4 , pp. 219-229
    • Zetter, B.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.