CD36-mediated activation of endothelial cell apoptosis by an N-terminal recombinant fragment of thrombospondin-2 inhibits breast cancer growth and metastasis in vivo

Breast Cancer Research and Treatment

Volumn 128, Issue 2, 2011, Pages 337-346

  Koch, Manuel ^a   Hussein, Fadi ^b   Woeste, Andreas ^a   Gründker, Carsten ^b   Frontzek, Karl ^b   Emons, Günter ^b   Hawighorst, Thomas ^b  

^a UNIVERSITY OF COLOGNE   (Germany)

^b UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

Author keywords

Angiogenesis; Breast cancer; CD36; Metastasis; Thrombospondin 2

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; CD36 ANTIGEN; HYBRID PROTEIN; IMMUNOGLOBULIN FC FRAGMENT; IMMUNOGLOBULIN G; RECOMBINANT PROTEIN; RECOMBINANT THROMBOSPONDIN 2; THROMBOSPONDIN 1; UNCLASSIFIED DRUG; VASCULOTROPIN;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER INHIBITION; CELL ACTIVATION; CONTROLLED STUDY; DISTANT METASTASIS; DRUG BLOOD LEVEL; DRUG POTENCY; ENZYME ACTIVATION; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG METASTASIS; LYMPH NODE METASTASIS; METASTASIS INHIBITION; MICROVASCULAR ENDOTHELIAL CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR VASCULARIZATION;

ANGIOGENESIS INHIBITORS; ANIMALS; ANTIGENS, CD36; APOPTOSIS; BLOTTING, WESTERN; BREAST NEOPLASMS; CASPASE 3; CELL ADHESION; CELL MOVEMENT; CELL PROLIFERATION; DERMIS; ENDOTHELIUM, VASCULAR; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; LUNG NEOPLASMS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, NUDE; NEOVASCULARIZATION, PATHOLOGIC; RECOMBINANT FUSION PROTEINS; THROMBOSPONDINS; TUMOR CELLS, CULTURED; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 79959706654     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-010-1085-7     Document Type: Article

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