Identifying the primary site of pathogenesis in amyotrophic lateral sclerosis - Vulnerability of lower motor neurons to proximal excitotoxicity

DMM Disease Models and Mechanisms

Volumn 8, Issue 3, 2015, Pages 215-224

  Blizzard, Catherine A ^a   Southam, Katherine A ^a   Dawkins, Edgar ^a   Lewis, Katherine E ^a   King, Anna E ^b   Clark, Jayden A ^a   Dickson, Tracey C ^a  

^a UNIVERSITY OF TASMANIA   (Australia)

^b UNIVERSITY OF TASMANIA   (Australia)

Author keywords

Amyotrophic lateral sclerosis; Excitotoxicity; Excitotoxin exposure; Lower motor neuron; Motor neuron disease

Indexed keywords

EXCITOTOXIN; KAINIC ACID; NEUROTOXIN;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL BODY; CELL DEATH; CONTROLLED STUDY; EXCITOTOXICITY; GASTROCNEMIUS MUSCLE; IN VITRO STUDY; IN VIVO STUDY; MOTONEURON; MOUSE; NERVE CELL DEGENERATION; NEUROMUSCULAR SYNAPSE; NONHUMAN; OSMOTIC MINIPUMP; PATHOGENESIS; PRIORITY JOURNAL; SPINAL CORD NERVE CELL; ANIMAL; C57BL MOUSE; CELL LINE; DRUG EFFECTS; FORELIMB; HINDLIMB; MOTOR ACTIVITY; NERVE DEGENERATION; NERVE FIBER; PATHOLOGY; PATHOPHYSIOLOGY; SPINAL CORD;

MUS;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; AXONS; CELL LINE; FORELIMB; HINDLIMB; KAINIC ACID; MICE, INBRED C57BL; MOTOR ACTIVITY; MOTOR NEURONS; NERVE DEGENERATION; NEUROTOXINS; SPINAL CORD;

EID: 84929144949     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.018606     Document Type: Article

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