PJ-34 inhibits PARP-1 expression and ERK phosphorylation in glioma-conditioned brain microvascular endothelial cells

European Journal of Pharmacology

Volumn 761, Issue , 2015, Pages 55-64

  Motta, Carla ^a   D'Angeli, Floriana ^a   Scalia, Marina ^a   Satriano, Cristina ^a   Barbagallo, Davide ^a   Naletova, Irina ^a   Anfuso, Carmelina Daniela ^a   Lupo, Gabriella ^a   Spina Purrello, Vittoria ^a  

^a UNIVERSITY OF CATANIA   (Italy)

Author keywords

C6 glioma cells; GP8.3 cells; PARP 1; PD98059; phospho ERK; PJ 34

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; MITOGEN ACTIVATED PROTEIN KINASE; N (5,6 DIHYDRO 6 OXO 2 PHENANTHRIDINYL) 2 DIMETHYLAMINOACETAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; TRANSCRIPTION FACTOR ELK 1; CONDITIONED MEDIUM; ELK1 PROTEIN, MOUSE; N-(OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)-N,N-DIMETHYLACETAMIDE HYDROCHLORIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; PARP1 PROTEIN, MOUSE; PHENANTHRENE DERIVATIVE; PROTEIN BINDING; PROTEIN KINASE INHIBITOR;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CAPILLARY ENDOTHELIAL CELL; CELL DIFFERENTIATION; CELL METABOLISM; CELL MIGRATION; CELL PROLIFERATION; CELL VIABILITY; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOPLASM; DRUG MECHANISM; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GLIOMA; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; ACTIVE TRANSPORT; ANIMAL; ANTAGONISTS AND INHIBITORS; BRAIN; BRAIN TUMOR; CELL MOTION; CONDITIONED MEDIUM; DRUG EFFECTS; ENDOTHELIUM CELL; ENZYMOLOGY; GENETICS; METABOLISM; MICROVASCULATURE; PARACRINE SIGNALING; PHOSPHORYLATION; TUMOR CELL LINE; VASCULARIZATION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; BRAIN; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; CULTURE MEDIA, CONDITIONED; ENDOTHELIAL CELLS; ETS-DOMAIN PROTEIN ELK-1; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GLIOMA; MICROVESSELS; PARACRINE COMMUNICATION; PHENANTHRENES; PHOSPHORYLATION; POLY(ADP-RIBOSE) POLYMERASE INHIBITORS; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN BINDING; PROTEIN KINASE INHIBITORS; RATS; SIGNAL TRANSDUCTION;

EID: 84929095957     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2015.04.026     Document Type: Article

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