Pharmacological inhibition of poly(ADP-ribose) polymerase-1 modulates resistance of human glioblastoma stem cells to temozolomide

BMC Cancer

Volumn 14, Issue 1, 2014, Pages

  Tentori, Lucio ^a   Ricci Vitiani, Lucia ^b   Muzi, Alessia ^a   Ciccarone, Fabio ^c,e   Pelacchi, Federica ^b   Calabrese, Roberta ^c,e   Runci, Daniele ^b   Pallini, Roberto ^d   Caiafa, Paola ^c,e   Graziani, Grazia ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d CATHOLIC UNIVERSITY   (Italy)

^e Pasteur Institute   (Italy)

Author keywords

Cancer stem cells; Chemoresistance; O6 methylguanine DNA methyltransferase; PARP inhibitor; Temozolomide

Indexed keywords

METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; TEMOZOLOMIDE; ALKYLATING AGENT; DACARBAZINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PARP1 PROTEIN, HUMAN;

ADULT; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER RESISTANCE; CANCER STEM CELL; CARCINOGENESIS; CLINICAL ARTICLE; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; DISEASE ACTIVITY; DNA METHYLATION; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENTIATION; DRUG SENSITIVITY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; GLIOBLASTOMA; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; MISMATCH REPAIR; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; PROMOTER REGION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; CPG ISLAND; DRUG EFFECTS; DRUG RESISTANCE; GENETICS; METABOLISM; MORTALITY; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, ALKYLATING; CELL LINE, TUMOR; CPG ISLANDS; DACARBAZINE; DNA METHYLATION; DRUG RESISTANCE, NEOPLASM; GLIOBLASTOMA; HUMANS; NEOPLASTIC STEM CELLS; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; POLY(ADP-RIBOSE) POLYMERASES; PROMOTER REGIONS, GENETIC;

EID: 84897573804     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-14-151     Document Type: Article

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