-
1
-
-
77950023283
-
PARP inhibition: PARP1 and beyond
-
Rouleau, M., Patel, A., Hendzel, M., Kaufmann, S. & Poirier, G. PARP inhibition: PARP1 and beyond. Nature Rev. Cancer 10, 293-301 (2010
-
(2010)
Nature Rev. Cancer
, vol.10
, pp. 293-301
-
-
Rouleau, M.1
Patel, A.2
Hendzel, M.3
Kaufmann, S.4
Poirier, G.5
-
2
-
-
25444463296
-
Poly ADP-ribose the most elaborate metabolite of NAD+
-
Bürkle, A. Poly(ADP-ribose). The most elaborate metabolite of NAD+. FEBS J. 272, 4576-4589 (2005
-
(2005)
FEBS J.
, vol.272
, pp. 4576-4589
-
-
Bürkle, A.1
-
3
-
-
53149094334
-
Substrate-assisted catalysis by PARP10 limits its activity to mono-ADP-ribosylation
-
Kleine, H. et al. Substrate-assisted catalysis by PARP10 limits its activity to mono-ADP-ribosylation. Mol. Cell 32, 57-69 (2008
-
(2008)
Mol. Cell
, vol.32
, pp. 57-69
-
-
Kleine, H.1
-
4
-
-
0028852624
-
Role of glutamic acid 988 of human poly-ADP-ribose polymerase in polymer formation. Evidence for active site similarities to the ADP-ribosylating toxins
-
Marsischky, G. T., Wilson, B. A. & Collier, R. J. Role of glutamic acid 988 of human poly-ADP-ribose polymerase in polymer formation. Evidence for active site similarities to the ADP-ribosylating toxins. J. Biol. Chem. 270, 3247-3254 (1995
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 3247-3254
-
-
Marsischky, G.T.1
Wilson, B.A.2
Collier, R.J.3
-
5
-
-
27644577665
-
In silico characterization of the family of PARP-like poly(ADP-ribosyl)transferases (pARTs)
-
Otto, H. et al. In silico characterization of the family of PARP-like poly(ADP-ribosyl)transferases (pARTs). BMC Genom. 6, 139 (2005
-
(2005)
BMC Genom.
, vol.6
, pp. 139
-
-
Otto, H.1
-
6
-
-
84857939963
-
Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors
-
Wahlberg, E. et al. Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors. Nature Biotech. 30, 283-288 (2012
-
(2012)
Nature Biotech.
, vol.30
, pp. 283-288
-
-
Wahlberg, E.1
-
7
-
-
0032562650
-
The mechanism of the elongation and branching reaction of poly(ADP-ribose) polymerase as derived from crystal structures and mutagenesis
-
Ruf, A., Rolli, V., de Murcia, G. & Schulz, G. The mechanism of the elongation and branching reaction of poly(ADP-ribose) polymerase as derived from crystal structures and mutagenesis. J. Mol. Biol. 278, 57-65 (1998
-
(1998)
J. Mol. Biol.
, vol.278
, pp. 57-65
-
-
Ruf, A.1
Rolli, V.2
De Murcia, G.3
Schulz, G.4
-
8
-
-
0036196923
-
The ARTT motif and a unified structural understanding of substrate recognition in ADP-ribosylating bacterial toxins and eukaryotic ADP-ribosyltransferases
-
Han, S. & Tainer, J. A. The ARTT motif and a unified structural understanding of substrate recognition in ADP-ribosylating bacterial toxins and eukaryotic ADP-ribosyltransferases. Int. J. Med. Microbiol. 291, 523-529 (2002
-
(2002)
Int. J. Med. Microbiol.
, vol.291
, pp. 523-529
-
-
Han, S.1
Tainer, J.A.2
-
9
-
-
0033198919
-
Poly ADP-ribosyl ation reactions in the regulation of nuclear functions
-
D?Amours, D., Desnoyers, S., D?Silva, I. & Poirier, G. Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions. Biochem. J. 342, 249-268 (1999
-
(1999)
Biochem. J.
, vol.342
, pp. 249-268
-
-
Damours, D.1
Desnoyers, S.2
Dsilva, I.3
Poirier, G.4
-
10
-
-
0023191708
-
Characterization of polymers of adenosine diphosphate ribose generated in vitro and in vivo
-
Alvarez-Gonzalez, R. & Jacobson, M. Characterization of polymers of adenosine diphosphate ribose generated in vitro and in vivo. Biochemistry 26, 3218-3224 (1987
-
(1987)
Biochemistry
, vol.26
, pp. 3218-3224
-
-
Alvarez-Gonzalez, R.1
Jacobson, M.2
-
11
-
-
0017366368
-
Natural occurence of a biopolymer, poly (adenosine diphosphate ribose
-
Sakura, H. et al. Natural occurence of a biopolymer, poly (adenosine diphosphate ribose). Nucleic Acids Res. 4, 2903-2915 (1977
-
(1977)
Nucleic Acids Res.
, vol.4
, pp. 2903-2915
-
-
Sakura, H.1
-
12
-
-
0032774019
-
Immunological determination and size characterization of poly(ADP-ribose) synthesized in vitro and in vivo
-
Affar, E. et al. Immunological determination and size characterization of poly(ADP-ribose) synthesized in vitro and in vivo. Biochim. Biophys. Acta 1428, 137-146 (1999
-
(1999)
Biochim. Biophys. Acta
, vol.1428
, pp. 137-146
-
-
Affar, E.1
-
13
-
-
84862758175
-
New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs
-
Gibson, B. & Kraus, W. New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs. Nature Rev. Mol. Cell Biol. 13, 411-424 (2012
-
(2012)
Nature Rev. Mol. Cell Biol.
, vol.13
, pp. 411-424
-
-
Gibson, B.1
Kraus, W.2
-
14
-
-
24744447821
-
The role of poly(ADP-ribose) in the DNA damage signaling network
-
Malanga, M. & Althaus, F. The role of poly(ADP-ribose) in the DNA damage signaling network. Biochem. Cell Biol. 83, 354-364 (2005
-
(2005)
Biochem. Cell Biol.
, vol.83
, pp. 354-364
-
-
Malanga, M.1
Althaus, F.2
-
15
-
-
70449102637
-
A nuclear poly(ADP-ribose)-dependent signalosome confers DNA damage-induced IκB kinase activation
-
Stilmann, M. et al. A nuclear poly(ADP-ribose)-dependent signalosome confers DNA damage-induced IκB kinase activation. Mol. Cell 36, 365-378 (2009
-
(2009)
Mol. Cell
, vol.36
, pp. 365-378
-
-
Stilmann, M.1
-
16
-
-
61449101465
-
Poly ADP-ribose polymerase 1 is required for protein localization to Cajal body
-
Kotova, E., Jarnik, M. & Tulin, A. Poly (ADP-ribose) polymerase 1 is required for protein localization to Cajal body. PLoS genet. 5, e1000387 (2009
-
(2009)
PLoS Genet.
, vol.5
-
-
Kotova, E.1
Jarnik, M.2
Tulin, A.3
-
17
-
-
79955957616
-
Poly ADP-ribose regulates stress responses and microRNA activity in the cytoplasm
-
Leung, A. et al. Poly(ADP-ribose) regulates stress responses and microRNA activity in the cytoplasm. Mol. Cell 42, 489-499 (2011
-
(2011)
Mol. Cell
, vol.42
, pp. 489-499
-
-
Leung, A.1
-
18
-
-
73949088211
-
Interaction between Poly(ADP-ribose) and NuMA contributes to mitotic spindle pole assembly
-
Chang, P., Coughlin, M. & Mitchison, T. J. Interaction between Poly(ADP-ribose) and NuMA contributes to mitotic spindle pole assembly. Mol. Biol. Cell 20, 4575-4585 (2009
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 4575-4585
-
-
Chang, P.1
Coughlin, M.2
Mitchison, T.J.3
-
19
-
-
84863010981
-
Recognition of the iso-ADP-ribose moiety in poly(ADP-ribose) by WWE domains suggests a general mechanism for poly(ADP-ribosyl)ation-dependent ubiquitination
-
Wang, Z. et al. Recognition of the iso-ADP-ribose moiety in poly(ADP-ribose) by WWE domains suggests a general mechanism for poly(ADP-ribosyl)ation-dependent ubiquitination. Genes Dev. 26, 235-240 (2012
-
(2012)
Genes Dev.
, vol.26
, pp. 235-240
-
-
Wang, Z.1
-
20
-
-
38049064044
-
Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins
-
Ahel, I. et al. Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins. Nature 451, 81-85 (2008
-
(2008)
Nature
, vol.451
, pp. 81-85
-
-
Ahel, I.1
-
21
-
-
21244444665
-
The macro domain is an ADP-ribose binding module
-
Karras, G. et al. The macro domain is an ADP-ribose binding module. EMBO J. 24, 1911-1920 (2005
-
(2005)
EMBO J.
, vol.24
, pp. 1911-1920
-
-
Karras, G.1
-
22
-
-
0034731455
-
Poly ADP-ribose binds to specific domains in DNA damage checkpoint proteins
-
Pleschke, J., Kleczkowska, H., Strohm, M. & Althaus, F. Poly(ADP-ribose) binds to specific domains in DNA damage checkpoint proteins. J. Biol. Chem. 275, 40974-40980 (2000
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 40974-40980
-
-
Pleschke, J.1
Kleczkowska, H.2
Strohm, M.3
Althaus, F.4
-
23
-
-
84880333185
-
The recognition and removal of cellular poly(ADP-ribose) signals
-
Barkauskaite, E., Jankevicius, G., Ladurner, A., Ahel, I. & Timinszky, G. The recognition and removal of cellular poly(ADP-ribose) signals. FEBS J. 280, 3491-3507 (2013
-
(2013)
FEBS J.
, vol.280
, pp. 3491-3507
-
-
Barkauskaite, E.1
Jankevicius, G.2
Ladurner, A.3
Ahel, I.4
Timinszky, G.5
-
24
-
-
0032568655
-
SMART a simple modular architecture research tool: Identification of signaling domains
-
Schultz, J., Milpetz, F., Bork, P. & Ponting, C. SMART, a simple modular architecture research tool: identification of signaling domains. Proc. Natl Acad. Sci. USA 95, 5857-5864 (1998
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 5857-5864
-
-
Schultz, J.1
Milpetz, F.2
Bork, P.3
Ponting, C.4
-
25
-
-
84862221167
-
SMART 7: Recent updates to the protein domain annotation resource
-
Letunic, I., Doerks, T. & Bork, P. SMART 7: recent updates to the protein domain annotation resource. Nucleic Acids Res. 40, 5 (2012
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 5
-
-
Letunic, I.1
Doerks, T.2
Bork, P.3
-
26
-
-
63149116496
-
Combining affinity purification by ADP-ribose-binding macro domains with mass spectrometry to define the mammalian ADP-ribosyl proteome
-
Dani, N. et al. Combining affinity purification by ADP-ribose-binding macro domains with mass spectrometry to define the mammalian ADP-ribosyl proteome. Proc. Natl Acad. Sci. USA 106, 4243-4248 (2009
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 4243-4248
-
-
Dani, N.1
-
27
-
-
84874456032
-
Recognition of mono-ADP-ribosylated ARTD10 substrates by ARTD8 macrodomains
-
Forst, A. et al. Recognition of mono-ADP-ribosylated ARTD10 substrates by ARTD8 macrodomains. Structure 21, 462-475 (2013
-
(2013)
Structure
, vol.21
, pp. 462-475
-
-
Forst, A.1
-
28
-
-
57749190795
-
Differential activities of cellular and viral macro domain proteins in binding of ADP-ribose metabolites
-
Neuvonen, M. & Ahola, T. Differential activities of cellular and viral macro domain proteins in binding of ADP-ribose metabolites. J. Mol. Biol. 385, 212-225 (2009
-
(2009)
J. Mol. Biol.
, vol.385
, pp. 212-225
-
-
Neuvonen, M.1
Ahola, T.2
-
29
-
-
84880324619
-
Expanding functions of intracellular resident mono-ADP-ribosylation in cell physiology
-
Feijs, K., Verheugd, P. & Lüscher, B. Expanding functions of intracellular resident mono-ADP-ribosylation in cell physiology. FEBS J. 280, 3519-3529 (2013
-
(2013)
FEBS J.
, vol.280
, pp. 3519-3529
-
-
Feijs, K.1
Verheugd, P.2
Lüscher, B.3
-
30
-
-
53849133471
-
Molecular mechanisms of the cytotoxicity of ADP-ribosylating toxins
-
Deng, Q. & Barbieri, J. Molecular mechanisms of the cytotoxicity of ADP-ribosylating toxins. Annu. Rev. Microbiol. 62, 271-288 (2008
-
(2008)
Annu. Rev. Microbiol.
, vol.62
, pp. 271-288
-
-
Deng, Q.1
Barbieri, J.2
-
31
-
-
6044269352
-
ModA and ModB, two ADP-ribosyltransferases encoded by bacteriophage T4: Catalytic properties and mutation analysis
-
Tiemann, B. et al. ModA and ModB, two ADP-ribosyltransferases encoded by bacteriophage T4: catalytic properties and mutation analysis. J. Bacteriol. 186, 7262-7272 (2004
-
(2004)
J. Bacteriol.
, vol.186
, pp. 7262-7272
-
-
Tiemann, B.1
-
32
-
-
24044441606
-
The mono-ADP-ribosyltransferases Alt and ModB of bacteriophage T4: Target proteins identified
-
Depping, R., Lohaus, C., Meyer, H. & Rüger, W. The mono-ADP-ribosyltransferases Alt and ModB of bacteriophage T4: target proteins identified. Biochem. Biophys. Res. Commun. 335, 1217-1223 (2005
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.335
, pp. 1217-1223
-
-
Depping, R.1
Lohaus, C.2
Meyer, H.3
Rüger, W.4
-
33
-
-
33748316536
-
SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic β cells
-
Haigis, M. et al. SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic β cells. Cell 126, 941-954 (2006
-
(2006)
Cell
, vol.126
, pp. 941-954
-
-
Haigis, M.1
-
34
-
-
20444409132
-
Mouse Sir2 homolog SIRT6 is a nuclear ADP-ribosyltransferase
-
Liszt, G., Ford, E., Kurtev, M. & Guarente, L. Mouse Sir2 homolog SIRT6 is a nuclear ADP-ribosyltransferase. J. Biol. Chem. 280, 21313-21320 (2005
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 21313-21320
-
-
Liszt, G.1
Ford, E.2
Kurtev, M.3
Guarente, L.4
-
35
-
-
0036086417
-
The family of toxin-related ecto-ADP-ribosyltransferases in humans and the mouse
-
Glowacki, G. et al. The family of toxin-related ecto-ADP- ribosyltransferases in humans and the mouse. Protein Sci. 11, 1657-1670 (2002
-
(2002)
Protein Sci.
, vol.11
, pp. 1657-1670
-
-
Glowacki, G.1
-
36
-
-
0029020255
-
ADP-ribosylation of Arg28 and Arg206 on the actin molecule by chicken arginine-specific ADP-ribosyltransferase
-
Terashima, M., Yamamori, C. & Shimoyama, M. ADP-ribosylation of Arg28 and Arg206 on the actin molecule by chicken arginine-specific ADP-ribosyltransferase. Eur. J. Biochem. 231, 242-249 (1995
-
(1995)
Eur. J. Biochem.
, vol.231
, pp. 242-249
-
-
Terashima, M.1
Yamamori, C.2
Shimoyama, M.3
-
37
-
-
0026584575
-
ADP-ribosylation of actins by arginine-specific ADP-ribosyltransferase purified from chicken heterophils
-
Terashima, M. et al. ADP-ribosylation of actins by arginine-specific ADP-ribosyltransferase purified from chicken heterophils. Eur. J. Biochem. 204, 305-311 (1992
-
(1992)
Eur. J. Biochem.
, vol.204
, pp. 305-311
-
-
Terashima, M.1
-
38
-
-
0027769708
-
ADP-ribosylation of the intermediate filament protein desmin and inhibition of desmin assembly in vitro by muscle ADP-ribosyltransferase
-
Huang, H., Graves, D., Robson, R. & Huiatt, T. ADP-ribosylation of the intermediate filament protein desmin and inhibition of desmin assembly in vitro by muscle ADP-ribosyltransferase. Biochem. Biophys. Res. Commun. 197, 570-577 (1993
-
(1993)
Biochem. Biophys. Res. Commun.
, vol.197
, pp. 570-577
-
-
Huang, H.1
Graves, D.2
Robson, R.3
Huiatt, T.4
-
39
-
-
0024846211
-
ADP-ribosylation of the 78-kDa glucose-regulated protein during nutritional stress
-
Gregory, H. L. & Barry, E. L. ADP-ribosylation of the 78-kDa glucose-regulated protein during nutritional stress. Eur. J. Biochem.186, 205-211 (1989
-
(1989)
Eur. J. Biochem
, vol.186
, pp. 205-211
-
-
Gregory, H.L.1
Barry, E.L.2
-
40
-
-
0032897211
-
The dynamic role of GRP78/BiP in the coordination of mRNA translation with protein processing
-
Laitusis, A., Brostrom, M. & Brostrom, C. The dynamic role of GRP78/BiP in the coordination of mRNA translation with protein processing. J. Biol. Chem. 274, 486-493 (1999
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 486-493
-
-
Laitusis, A.1
Brostrom, M.2
Brostrom, C.3
-
41
-
-
0028134743
-
ADP-ribosylation of the molecular chaperone GRP78/BiP
-
Ledford, B. & Leno, G. ADP-ribosylation of the molecular chaperone GRP78/BiP. Mol. Cell. Biochem. 138, 141-148 (1994
-
(1994)
Mol. Cell. Biochem.
, vol.138
, pp. 141-148
-
-
Ledford, B.1
Leno, G.2
-
42
-
-
84866455655
-
ADP ribosylation adapts an ER chaperone response to short-term fluctuations in unfolded protein load
-
Chambers, J., Petrova, K., Tomba, G., Vendruscolo, M. & Ron, D. ADP ribosylation adapts an ER chaperone response to short-term fluctuations in unfolded protein load. J. Cell Biol. 198, 371-385 (2012
-
(2012)
J. Cell Biol.
, vol.198
, pp. 371-385
-
-
Chambers, J.1
Petrova, K.2
Tomba, G.3
Vendruscolo, M.4
Ron, D.5
-
43
-
-
0034737579
-
Endogenous ADP-ribosylation of the G protein β subunit prevents the inhibition of type 1 adenylyl cyclase
-
Lupi, R., Corda, D. & Di Girolamo, M. Endogenous ADP-ribosylation of the G protein β subunit prevents the inhibition of type 1 adenylyl cyclase. J. Biol. Chem. 275, 9418-9424 (2000
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 9418-9424
-
-
Lupi, R.1
Corda, D.2
Di Girolamo, M.3
-
44
-
-
18644377447
-
Endogenous mono-ADP-ribosylation of the free Gβγ prevents stimulation of phosphoinositide 3-kinase-gamma and phospholipase C-β2 and is activated by G-protein-coupled receptors
-
Lupi, R. et al. Endogenous mono-ADP-ribosylation of the free Gβγ prevents stimulation of phosphoinositide 3-kinase-gamma and phospholipase C-β2 and is activated by G-protein-coupled receptors. Biochem. J. 367, 825-832 (2002
-
(2002)
Biochem. J.
, vol.367
, pp. 825-832
-
-
Lupi, R.1
-
45
-
-
0030917447
-
Residues within the polycationic region of cGMP phosphodiesterase β subunit crucial for the interaction with transducin alpha subunit. Identification by endogenous ADP-rybosylation and site directed mutagenesis
-
Bondarenko, V. A. et al. Residues within the polycationic region of cGMP phosphodiesterase β subunit crucial for the interaction with transducin alpha subunit. Identification by endogenous ADP-rybosylation and site directed mutagenesis. J. Biol. Chem. 272, 15856-15864 (1997
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 15856-15864
-
-
Bondarenko, V.A.1
-
46
-
-
0033564891
-
Suppression of GTP/T alpha-dependent activation of cGMP phosphodiesterase by ADP-ribosylation by its gamma subunit in amphibian rod photoreceptor membranes
-
Bondarenko, V., Yamazaki, M., Hayashi, F. & Yamazaki, A. Suppression of GTP/T alpha-dependent activation of cGMP phosphodiesterase by ADP-ribosylation by its gamma subunit in amphibian rod photoreceptor membranes. Biochemistry 38, 7755-7763 (1999
-
(1999)
Biochemistry
, vol.38
, pp. 7755-7763
-
-
Bondarenko, V.1
Yamazaki, M.2
Hayashi, F.3
Yamazaki, A.4
-
47
-
-
79953169502
-
Mono-ADP-ribosylation of the G protein βγ dimer is modulated by hormones and inhibited by Arf6
-
Dani, N. et al. Mono-ADP-ribosylation of the G protein βγ dimer is modulated by hormones and inhibited by Arf6. J. Biol. Chem. 286, 5995-6005 (2011
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 5995-6005
-
-
Dani, N.1
-
48
-
-
67649888368
-
Molecular mechanism of poly(ADP-ribosyl)ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sites
-
Altmeyer, M., Messner, S., Hassa, P., Fey, M. & Hottiger, M. Molecular mechanism of poly(ADP-ribosyl)ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sites. Nucleic Acids Res. 37, 3723-3738 (2009
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. 3723-3738
-
-
Altmeyer, M.1
Messner, S.2
Hassa, P.3
Fey, M.4
Hottiger, M.5
-
49
-
-
78049376054
-
PARP1 ADP-ribosylates lysine residues of the core histone tails
-
Messner, S. et al. PARP1 ADP-ribosylates lysine residues of the core histone tails. Nucleic Acids Res. 38, 6350-6362 (2010
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 6350-6362
-
-
Messner, S.1
-
50
-
-
70349935191
-
Identification of the ADP-ribosylation sites in the PARP-1 automodification domain: Analysis and implications
-
Tao, Z. Gao, P. & Liu, H.-w. Identification of the ADP-ribosylation sites in the PARP-1 automodification domain: analysis and implications. J. Am. Chem. Soc. 131, 14258-14260 (2009
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 14258-14260
-
-
Tao, Z.1
Gao, P.2
Liu, H.-W.3
-
51
-
-
84869094697
-
PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK-and IRE1β-mediated unfolded protein response
-
Jwa, M. & Chang, P. PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK-and IRE1β-mediated unfolded protein response. Nature Cell Biol. 14, 1223-1230 (2012
-
(2012)
Nature Cell Biol.
, vol.14
, pp. 1223-1230
-
-
Jwa, M.1
Chang, P.2
-
52
-
-
84882437564
-
A systematic analysis of the PARP protein family identifies new functions critical for cell physiology
-
Vyas, S., Chesarone-Cataldo, M., Todorova, T., Huang, Y. H. & Chang, P. A systematic analysis of the PARP protein family identifies new functions critical for cell physiology. Nature Commun. 4, 2240 (2013
-
(2013)
Nature Commun.
, vol.4
, pp. 2240
-
-
Vyas, S.1
Chesarone-Cataldo, M.2
Todorova, T.3
Huang, Y.H.4
Chang, P.5
-
53
-
-
84857891632
-
On PAR with PARP: Cellular stress signaling through poly(ADP-ribose) and PARP-1
-
Luo, X. & Kraus, W. On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1. Genes Dev. 26, 417-432 (2012
-
(2012)
Genes Dev.
, vol.26
, pp. 417-432
-
-
Luo, X.1
Kraus, W.2
-
54
-
-
84880333963
-
A role of intracellular mono-ADP-ribosylation in cancer biology
-
Scarpa, E., Fabrizio, G. & Di Girolamo, M. A role of intracellular mono-ADP-ribosylation in cancer biology. FEBS J. 280, 3551-3562 (2013
-
(2013)
FEBS J.
, vol.280
, pp. 3551-3562
-
-
Scarpa, E.1
Fabrizio, G.2
Di Girolamo, M.3
-
55
-
-
84876733507
-
ADP-ribosylated proteins as old and new drug targets for anticancer therapy: The example of ARF6
-
Dani, N., Barbosa, A. J., Del Rio, A. & Di Girolamo, M. ADP-ribosylated proteins as old and new drug targets for anticancer therapy: the example of ARF6. Curr. Pharm. Des. 19, 624-633 (2013
-
(2013)
Curr. Pharm. Des.
, vol.19
, pp. 624-633
-
-
Dani, N.1
Barbosa, A.J.2
Del Rio, A.3
Di Girolamo, M.4
-
56
-
-
84885995929
-
Reciprocal Inhibition between intracellular antiviral signaling and the RNAi machinery in mammalian cells
-
Seo, G. et al. Reciprocal Inhibition between intracellular antiviral signaling and the RNAi machinery in mammalian cells. Cell Host Microbe 14, 435-445 (2013
-
(2013)
Cell Host Microbe
, vol.14
, pp. 435-445
-
-
Seo, G.1
-
57
-
-
84877724803
-
Regulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10
-
Verheugd, P. et al. Regulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10. Nature Commun. 4, 1683 (2013
-
(2013)
Nature Commun.
, vol.4
, pp. 1683
-
-
Verheugd, P.1
-
58
-
-
84883743073
-
Poly(ADP-ribose) polymerase family member 14 (PARP14) is a novel effector of the JNK2-dependent pro-survival signal in multiple myeloma
-
Barbarulo, A. et al. Poly(ADP-ribose) polymerase family member 14 (PARP14) is a novel effector of the JNK2-dependent pro-survival signal in multiple myeloma. Oncogene 32, 4231-4242 (2013
-
(2013)
Oncogene
, vol.32
, pp. 4231-4242
-
-
Barbarulo, A.1
-
59
-
-
33645243011
-
Selective potentiation of Stat-dependent gene expression by collaborator of Stat6 (CoaSt6), a transcriptional cofactor
-
Goenka, S. & Boothby, M. Selective potentiation of Stat-dependent gene expression by collaborator of Stat6 (CoaSt6), a transcriptional cofactor. Proc. Natl Acad. Sci. USA 103, 4210-4215 (2006
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 4210-4215
-
-
Goenka, S.1
Boothby, M.2
-
60
-
-
0034672418
-
BAL is a novel risk-related gene in diffuse large B-cell lymphomas that enhances cellular migration
-
Aguiar, R. et al. BAL is a novel risk-related gene in diffuse large B-cell lymphomas that enhances cellular migration. Blood 96, 4328-4334 (2000
-
(2000)
Blood
, vol.96
, pp. 4328-4334
-
-
Aguiar, R.1
-
61
-
-
0032873278
-
The 193-kD vault protein, VPARP, is a novel poly(ADP-ribose) polymerase
-
Kickhoefer, V. A. et al. The 193-kD vault protein, VPARP, is a novel poly(ADP-ribose) polymerase. J. Cell Biol. 146, 917-928 (1999
-
(1999)
J. Cell Biol.
, vol.146
, pp. 917-928
-
-
Kickhoefer, V.A.1
-
62
-
-
84869786773
-
PARP6, a mono(ADP-ribosyl) transferase and a negative regulator of cell proliferation, is involved in colorectal cancer development
-
Tuncel, H. et al. PARP6, a mono(ADP-ribosyl) transferase and a negative regulator of cell proliferation, is involved in colorectal cancer development. Int. J. Oncol. 41, 2079-2086 (2012
-
(2012)
Int. J. Oncol.
, vol.41
, pp. 2079-2086
-
-
Tuncel, H.1
-
63
-
-
0035976732
-
TCDD-inducible poly(ADP-ribose) polymerase: A novel response to 2,3,7,8-tetrachlorodibenzo-p-dioxin
-
Ma, Q., Baldwin, K., Renzelli, A., McDaniel, A. & Dong, L. TCDD-inducible poly(ADP-ribose) polymerase: a novel response to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Biochem. Biophys. Res. Commun. 289, 499-506 (2001
-
(2001)
Biochem. Biophys. Res. Commun
, vol.289
, pp. 499-506
-
-
Ma, Q.1
Baldwin, K.2
Renzelli, A.3
Mc Daniel, A.4
Dong, L.5
-
64
-
-
84873694897
-
2,3,7,8-Tetrachlorodibenzo-p-dioxin poly(ADP-ribose) polymerase (TiPARP, ARTD14) is a mono-ADP-ribosyltransferase and repressor of aryl hydrocarbon receptor transactivation
-
MacPherson, L. et al. 2,3,7,8-Tetrachlorodibenzo-p-dioxin poly(ADP-ribose) polymerase (TiPARP, ARTD14) is a mono-ADP-ribosyltransferase and repressor of aryl hydrocarbon receptor transactivation. Nucleic Acids Res. 41, 1604-1621 (2013
-
(2013)
Nucleic Acids Res
, vol.41
, pp. 1604-1621
-
-
Mac Pherson, L.1
-
65
-
-
82255173966
-
The unfolded protein response: From stress pathway to homeostatic regulation
-
Walter, P. & Ron, D. The unfolded protein response: from stress pathway to homeostatic regulation. Science 334, 1081-1086 (2011
-
(2011)
Science
, vol.334
, pp. 1081-1086
-
-
Walter, P.1
Ron, D.2
-
66
-
-
79952844773
-
The unfolded protein response, degradation from endoplasmic reticulum and cancer
-
Tsai, Y. & Weissman, A. The unfolded protein response, degradation from endoplasmic reticulum and cancer. Genes Cancer 1, 764-778 (2010
-
(2010)
Genes Cancer
, vol.1
, pp. 764-778
-
-
Tsai, Y.1
Weissman, A.2
-
67
-
-
84875235453
-
Characterization of a novel PERK kinase inhibitor with antitumor and antiangiogenic activity
-
Atkins, C. et al. Characterization of a novel PERK kinase inhibitor with antitumor and antiangiogenic activity. Cancer Res. 73, 1993-2002 (2013
-
(2013)
Cancer Res.
, vol.73
, pp. 1993-2002
-
-
Atkins, C.1
-
68
-
-
79251589342
-
Identification of an Ire1α endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma
-
Papandreou, I. et al. Identification of an Ire1α endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma. Blood 117, 1311-1314 (2011
-
(2011)
Blood
, vol.117
, pp. 1311-1314
-
-
Papandreou, I.1
-
69
-
-
84862501186
-
Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma
-
Mimura, N. et al. Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma. Blood 119, 5772-5781 (2012
-
(2012)
Blood
, vol.119
, pp. 5772-5781
-
-
Mimura, N.1
-
70
-
-
84862233980
-
PARP16/ARTD15 is a novel endoplasmic-reticulum-associated mono-ADP-ribosyltransferase that interacts with, and modifies karyopherin-β1
-
Di Paola, S., Micaroni, M., Di Tullio, G., Buccione, R. & Di Girolamo, M. PARP16/ARTD15 is a novel endoplasmic-reticulum-associated mono-ADP-ribosyltransferase that interacts with, and modifies karyopherin-β1. PloS one 7, e37352 (2012
-
(2012)
PloS One
, vol.7
-
-
Di Paola, S.1
Micaroni, M.2
Di Tullio, G.3
Buccione, R.4
Di Girolamo, M.5
-
71
-
-
33646481320
-
Direct phosphorylation and regulation of poly(ADP-ribose) polymerase-1 by extracellular signal-regulated kinases 1/2
-
Kauppinen, T. et al. Direct phosphorylation and regulation of poly(ADP-ribose) polymerase-1 by extracellular signal-regulated kinases 1/2. Proc. Natl Acad. Sci. USA 103, 7136-7141 (2006
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 7136-7141
-
-
Kauppinen, T.1
-
72
-
-
33846362869
-
DNA-independent PARP-1 activation by phosphorylated ERK2 increases Elk1 activity: A link to histone acetylation
-
Cohen-Armon, M. et al. DNA-independent PARP-1 activation by phosphorylated ERK2 increases Elk1 activity: a link to histone acetylation. Mol. Cell 25, 297-308 (2007
-
(2007)
Mol. Cell
, vol.25
, pp. 297-308
-
-
Cohen-Armon, M.1
-
73
-
-
33749605969
-
Mitotic phosphorylation of tankyrase, a PARP that promotes spindle assembly, by GSK3
-
Yeh, T. Y., Sbodio, J. I. & Chi, N. W. Mitotic phosphorylation of tankyrase, a PARP that promotes spindle assembly, by GSK3. Biochem. Biophys. Res. Commun. 350, 574-579 (2006
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.350
, pp. 574-579
-
-
Yeh, T.Y.1
Sbodio, J.I.2
Chi, N.W.3
-
74
-
-
41049105321
-
IPI-504, a novel and soluble HSP-90 inhibitor, blocks the unfolded protein response in multiple myeloma cells
-
Patterson, J., Palombella, V., Fritz, C. & Normant, E. IPI-504, a novel and soluble HSP-90 inhibitor, blocks the unfolded protein response in multiple myeloma cells. Cancer Chemother. Pharmacol. 61, 923-932 (2008
-
(2008)
Cancer Chemother. Pharmacol.
, vol.61
, pp. 923-932
-
-
Patterson, J.1
Palombella, V.2
Fritz, C.3
Normant, E.4
-
75
-
-
33744539521
-
Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells
-
Obeng, E. et al. Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells. Blood 107, 4907-4916 (2006
-
(2006)
Blood
, vol.107
, pp. 4907-4916
-
-
Obeng, E.1
-
76
-
-
39949085583
-
Stress granules: The Tao of RNA triage
-
Anderson, P. & Kedersha, N. Stress granules: the Tao of RNA triage. Trends Biochem. Sci. 33, 141-150 (2008
-
(2008)
Trends Biochem. Sci.
, vol.33
, pp. 141-150
-
-
Anderson, P.1
Kedersha, N.2
-
77
-
-
55549130760
-
Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways
-
Arimoto, K., Fukuda, H., Imajoh-Ohmi, S., Saito, H. & Takekawa, M. Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways. Nature Cell Biol. 10, 1324-1332 (2008
-
(2008)
Nature Cell Biol.
, vol.10
, pp. 1324-1332
-
-
Arimoto, K.1
Fukuda, H.2
Imajoh-Ohmi, S.3
Saito, H.4
Takekawa, M.5
-
78
-
-
84882800242
-
Inhibition of mTORC1 by astrin and stress granules prevents apoptosis in cancer cells
-
Kathrin, T. et al. Inhibition of mTORC1 by astrin and stress granules prevents apoptosis in cancer cells. Cell 154, 859-874 (2013
-
(2013)
Cell
, vol.154
, pp. 859-874
-
-
Kathrin, T.1
-
79
-
-
79957534572
-
Targeting hypoxia in cancer therapy
-
Wilson, W. & Hay, M. Targeting hypoxia in cancer therapy. Nature Rev. Cancer 11, 393-410 (2011
-
(2011)
Nature Rev. Cancer
, vol.11
, pp. 393-410
-
-
Wilson, W.1
Hay, M.2
-
80
-
-
33745855438
-
Efficacy comparisons in solid tumors and hematologic malignancies
-
Caravita, T., de Fabritiis, P., Palumbo, A., Amadori, S. & Boccadoro, M. Bortezomib: efficacy comparisons in solid tumors and hematologic malignancies. Nature Clin. Pract. Oncol. 3, 374-387 (2006
-
(2006)
Nature Clin. Pract. Oncol.
, vol.3
, pp. 374-387
-
-
Caravita, T.1
De Fabritiis, P.2
Palumbo, A.3
Amadori, S.4
Bortezomib, B.M.5
-
81
-
-
77951598447
-
The chemotherapeutic agent bortezomib induces the formation of stress granules
-
Fournier, M.-J., Gareau, C. & Mazroui, R. The chemotherapeutic agent bortezomib induces the formation of stress granules. Cancer Cell. Int. 10, 12 (2010
-
(2010)
Cancer Cell. Int.
, vol.10
, pp. 12
-
-
Fournier, M.-J.1
Gareau, C.2
Mazroui, R.3
-
82
-
-
3042767202
-
Correction: Micro RNAs: Small RNAs with a big role in gene regulation
-
Lin, H. & Gregory, J. H. Correction: MicroRNAs: small RNAs with a big role in gene regulation. Nature Rev. Genet. 5, 522-531 (2004
-
(2004)
Nature Rev. Genet.
, vol.5
, pp. 522-531
-
-
Lin, H.1
Gregory, J.H.2
-
83
-
-
77949451963
-
Argonaute proteins: Potential biomarkers for human colon cancer
-
Li, L., Yu, C., Gao, H. & Li, Y. Argonaute proteins: potential biomarkers for human colon cancer. BMC Cancer 10, 38 (2010
-
(2010)
BMC Cancer
, vol.10
, pp. 38
-
-
Li, L.1
Yu, C.2
Gao, H.3
Li, Y.4
-
84
-
-
84876712708
-
Argonaute2 promotes tumor metastasis by way of up-regulating focal adhesion kinase expression in hepatocellular carcinoma
-
Cheng, N., Li, Y. & Han, Z.-G. Argonaute2 promotes tumor metastasis by way of up-regulating focal adhesion kinase expression in hepatocellular carcinoma. Hepatology 57, 1906-1918 (2013
-
(2013)
Hepatology
, vol.57
, pp. 1906-1918
-
-
Cheng, N.1
Li, Y.2
Han, Z.-G.3
-
85
-
-
84857784512
-
Senescence is an endogenous trigger for microRNA-directed transcriptional gene silencing in human cells
-
Benhamed, M., Herbig, U., Ye, T., Dejean, A. & Bischof, O. Senescence is an endogenous trigger for microRNA-directed transcriptional gene silencing in human cells. Nature Cell Biol. 14, 266-275 (2012
-
(2012)
Nature Cell Biol.
, vol.14
, pp. 266-275
-
-
Benhamed, M.1
Herbig, U.2
Ye, T.3
Dejean, A.4
Bischof, O.5
-
86
-
-
84872794144
-
Overexpression of human Argonaute2 inhibits cell and tumor growth
-
Zhang, X., Graves, P. & Zeng, Y. Overexpression of human Argonaute2 inhibits cell and tumor growth. Biochim. Biophys. Acta 1830, 2553-2561 (2013
-
(2013)
Biochim. Biophys. Acta
, vol.1830
, pp. 2553-2561
-
-
Zhang, X.1
Graves, P.2
Zeng, Y.3
-
87
-
-
84890429103
-
Strong reduction of AGO2 expression in melanoma and cellular consequences
-
Völler, D., Reinders, J., Meister, G. & Bosserhoff, A. K. Strong reduction of AGO2 expression in melanoma and cellular consequences. Br. J. Cancer 109, 3116-3124 (2013
-
(2013)
Br. J. Cancer
, vol.109
, pp. 3116-3124
-
-
Völler, D.1
Reinders, J.2
Meister, G.3
Bosserhoff, A.K.4
-
88
-
-
20144389675
-
PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation
-
Yu, M. et al. PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation. Oncogene 24, 1982-1993 (2005
-
(2005)
Oncogene
, vol.24
, pp. 1982-1993
-
-
Yu, M.1
-
89
-
-
33748192942
-
The Myc oncoprotein as a therapeutic target for human cancer
-
Vita, M. & Henriksson, M. The Myc oncoprotein as a therapeutic target for human cancer. Semin. Cancer Biol. 16, 318-330 (2006
-
(2006)
Semin. Cancer Biol.
, vol.16
, pp. 318-330
-
-
Vita, M.1
Henriksson, M.2
-
90
-
-
33744965941
-
CDK-dependent activation of poly(ADP-ribose) polymerase member 10 (PARP10
-
Chou, H.-Y. E., Chou, H. & Lee, S.-C. CDK-dependent activation of poly(ADP-ribose) polymerase member 10 (PARP10). J. Biol. Chem. 281, 15201-15207 (2006
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 15201-15207
-
-
Chou, H.-Y.E.1
Chou, H.2
Lee, S.-C.3
-
91
-
-
84874486452
-
Caspase-dependent cleavage of the mono-ADP-ribosyltransferase ARTD10 interferes with its pro-apoptotic function
-
Herzog, N. et al. Caspase-dependent cleavage of the mono-ADP- ribosyltransferase ARTD10 interferes with its pro-apoptotic function. FEBS J. 280, 1330-1343 (2013
-
(2013)
FEBS J.
, vol.280
, pp. 1330-1343
-
-
Herzog, N.1
-
92
-
-
84870512471
-
Dynamic subcellular localization of the mono-ADP-ribosyltransferase ARTD10 and interaction with the ubiquitin receptor p62
-
Kleine, H. et al. Dynamic subcellular localization of the mono-ADP-ribosyltransferase ARTD10 and interaction with the ubiquitin receptor p62. Cell Commun. Signal. 10, 28 (2012
-
(2012)
Cell Commun. Signal.
, vol.10
, pp. 28
-
-
Kleine, H.1
-
93
-
-
36448943299
-
Role of autophagy in cancer
-
Mathew, R., Karantza-Wadsworth, V. & White, E. Role of autophagy in cancer. Nature Rev. Cancer 7, 961-967 (2007
-
(2007)
Nature Rev. Cancer
, vol.7
, pp. 961-967
-
-
Mathew, R.1
Karantza-Wadsworth, V.2
White, E.3
-
94
-
-
80052697287
-
The role of autophagy in cancer: Therapeutic implications
-
Yang, Z. J., Chee, C. E., Huang, S. & Sinicrope, F. A. The role of autophagy in cancer: therapeutic implications. Mol. Cancer Ther. 10, 1533-1541 (2011
-
(2011)
Mol. Cancer Ther.
, vol.10
, pp. 1533-1541
-
-
Yang, Z.J.1
Chee, C.E.2
Huang, S.3
Sinicrope, F.A.4
-
95
-
-
84887437596
-
Autophagy and chemotherapy resistance: A promising therapeutic target for cancer treatment
-
Sui, X. et al. Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment. Cell Death Dis. 4, e838 (2013
-
(2013)
Cell Death Dis.
, vol.4
-
-
Sui, X.1
-
96
-
-
84878992314
-
Autophagy inhibition sensitizes colon cancer cells to antiangiogenic and cytotoxic therapy
-
Selvakumaran, M., Amaravadi, R., Vasilevskaya, I. & O?Dwyer, P. Autophagy inhibition sensitizes colon cancer cells to antiangiogenic and cytotoxic therapy. Clin. Cancer Res. 19, 2995-3007 (2013
-
(2013)
Clin. Cancer Res.
, vol.19
, pp. 2995-3007
-
-
Selvakumaran, M.1
Amaravadi, R.2
Vasilevskaya, I.3
Odwyer, P.4
-
97
-
-
79952229430
-
Pancreatic cancers require autophagy for tumor growth
-
Yang, S. et al. Pancreatic cancers require autophagy for tumor growth. Genes Dev. 25, 717-729 (2011
-
(2011)
Genes Dev.
, vol.25
, pp. 717-729
-
-
Yang, S.1
-
98
-
-
33745713171
-
Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis
-
Degenhardt, K. et al. Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis. Cancer Cell 10, 51-64 (2006
-
(2006)
Cancer Cell
, vol.10
, pp. 51-64
-
-
Degenhardt, K.1
-
99
-
-
34347404887
-
Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis
-
Karantza-Wadsworth, V. et al. Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis. Genes Dev. 21, 1621-1635 (2007
-
(2007)
Genes Dev.
, vol.21
, pp. 1621-1635
-
-
Karantza-Wadsworth, V.1
-
100
-
-
84856227062
-
The complex interplay between autophagy and NF-κB signaling pathways in cancer cells
-
Trocoli, A. & Djavaheri-Mergny, M. The complex interplay between autophagy and NF-κB signaling pathways in cancer cells. Am. J. Cancer. Res.1, 629-649 (2011
-
(2011)
Am. J. Cancer. Res.
, vol.1
, pp. 629-649
-
-
Trocoli, A.1
Djavaheri-Mergny, M.2
-
101
-
-
34547112062
-
Collaborator of Stat6 (CoaSt6)-associated poly(ADP-ribose) polymerase activity modulates Stat6-dependent gene transcription
-
Goenka, S., Cho, S. & Boothby, M. Collaborator of Stat6 (CoaSt6)-associated poly(ADP-ribose) polymerase activity modulates Stat6-dependent gene transcription. J. Biol. Chem. 282, 18732-18739 (2007
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 18732-18739
-
-
Goenka, S.1
Cho, S.2
Boothby, M.3
-
102
-
-
63849298103
-
PARP-14, a member of the B aggressive lymphoma family, transduces survival signals in primary B cells
-
Cho, S. et al. PARP-14, a member of the B aggressive lymphoma family, transduces survival signals in primary B cells. Blood 113, 2416-2425 (2009
-
(2009)
Blood
, vol.113
, pp. 2416-2425
-
-
Cho, S.1
-
103
-
-
80053158632
-
Glycolytic rate and lymphomagenesis depend on PARP14, an ADP ribosyltransferase of the B aggressive lymphoma (BAL) family
-
Cho, S. et al. Glycolytic rate and lymphomagenesis depend on PARP14, an ADP ribosyltransferase of the B aggressive lymphoma (BAL) family. Proc. Natl Acad. Sci. USA 108, 15972-15977 (2011
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 15972-15977
-
-
Cho, S.1
-
104
-
-
0038049137
-
Tumour-cell invasion and migration: Diversity and escape mechanisms
-
Friedl, P. & Wolf, K. Tumour-cell invasion and migration: diversity and escape mechanisms. Nature Rev. Cancer 3, 362-374 (2003
-
(2003)
Nature Rev. Cancer
, vol.3
, pp. 362-374
-
-
Friedl, P.1
Wolf, K.2
-
105
-
-
79960790148
-
Chemotaxis in cancer
-
Roussos, E., Condeelis, J. & Patsialou, A. Chemotaxis in cancer. Nature Rev. Cancer 11, 573-587 (2011
-
(2011)
Nature Rev. Cancer
, vol.11
, pp. 573-587
-
-
Roussos, E.1
Condeelis, J.2
Patsialou, A.3
-
106
-
-
33745848147
-
BAL1 and BBAP are regulated by a gamma interferon-responsive bidirectional promoter and are overexpressed in diffuse large B-cell lymphomas with a prominent inflammatory infiltrate
-
Juszczynski, P. et al. BAL1 and BBAP are regulated by a gamma interferon-responsive bidirectional promoter and are overexpressed in diffuse large B-cell lymphomas with a prominent inflammatory infiltrate. Mol. Cell. Biol. 26, 5348-5359 (2006
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 5348-5359
-
-
Juszczynski, P.1
-
107
-
-
0024412051
-
Recombinant IL-4 and IFN-γ activate locomotor capacity in human B lymphocytes
-
Wilkinson, P. & Islam, L. Recombinant IL-4 and IFN-γ activate locomotor capacity in human B lymphocytes. Immunology 67, 237-243 (1989
-
(1989)
Immunology
, vol.67
, pp. 237-243
-
-
Wilkinson, P.1
Islam, L.2
-
108
-
-
0027516969
-
The effect of T cell-derived cytokines on B cell motility in vitro
-
Clinchy, B., Elenstrom, C. & Moller, G. The effect of T cell-derived cytokines on B cell motility in vitro. Cell. Immunol. 146, 62-70 (1993
-
(1993)
Cell. Immunol.
, vol.146
, pp. 62-70
-
-
Clinchy, B.1
Elenstrom, C.2
Moller, G.3
-
109
-
-
80053469514
-
The two faces of interferon-γ in cancer
-
Zaidi, M. & Merlino, G. The two faces of interferon-γ in cancer. Clin. Cancer Res. 17, 6118-6124 (2011
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 6118-6124
-
-
Zaidi, M.1
Merlino, G.2
-
110
-
-
0141960414
-
Is interferon β one key of metastatic potential increase in human bladder carcinoma? Clin
-
Champelovier, P. et al. Is interferon β one key of metastatic potential increase in human bladder carcinoma? Clin. Cancer Res. 9, 4562-4569 (2003
-
(2003)
Cancer Res.
, vol.9
, pp. 4562-4569
-
-
Champelovier, P.1
-
111
-
-
0027490205
-
Inhibition of tumor growth and enhancement of metastasis after transfection of the β-interferon gene
-
Lollini, P. et al. Inhibition of tumor growth and enhancement of metastasis after transfection of the β-interferon gene. Int. J. Cancer 55, 320-329 (1993
-
(1993)
Int. J. Cancer
, vol.55
, pp. 320-329
-
-
Lollini, P.1
-
112
-
-
0035216135
-
Interferon-gamma receptor 2 expression as the deciding factor in human T, B, and myeloid cell proliferation or death
-
Bernabei, P. et al. Interferon-gamma receptor 2 expression as the deciding factor in human T, B, and myeloid cell proliferation or death. J. Leukocyte Biol. 70, 950-960 (2001
-
(2001)
J. Leukocyte Biol.
, vol.70
, pp. 950-960
-
-
Bernabei, P.1
-
113
-
-
26644446700
-
B-aggressive lymphoma family proteins have unique domains that modulate transcription and exhibit poly(ADP-ribose) polymerase activity
-
Aguiar, R., Takeyama, K., He, C., Kreinbrink, K. & Shipp, M. B-aggressive lymphoma family proteins have unique domains that modulate transcription and exhibit poly(ADP-ribose) polymerase activity. J. Biol. Chem. 280, 33756-33765 (2005
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 33756-33765
-
-
Aguiar, R.1
Takeyama, K.2
He, C.3
Kreinbrink, K.4
Shipp, M.5
-
114
-
-
79953303384
-
Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation
-
Kuo, J.-C., Han, X., Hsiao, C.-T., Yates, J. & Waterman, C. Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation. Nature Cell Biol. 13, 383-393 (2011
-
(2011)
Nature Cell Biol.
, vol.13
, pp. 383-393
-
-
Kuo, J.-C.1
Han, X.2
Hsiao, C.-T.3
Yates, J.4
Waterman, C.5
-
115
-
-
84869042621
-
A combinatorial extracellular matrix platform identifies cell-extracellular matrix interactions that correlate with metastasis
-
Reticker-Flynn, N. et al. A combinatorial extracellular matrix platform identifies cell-extracellular matrix interactions that correlate with metastasis. Nature Commun. 3, 1122 (2012
-
(2012)
Nature Commun.
, vol.3
, pp. 1122
-
-
Reticker-Flynn, N.1
-
116
-
-
0028808210
-
Fibronectin and integrins in invasion and metastasis
-
Akiyama, S., Olden, K. & Yamada, K. Fibronectin and integrins in invasion and metastasis. Cancer Metastasis Rev. 14, 173-189 (1995
-
(1995)
Cancer Metastasis Rev.
, vol.14
, pp. 173-189
-
-
Akiyama, S.1
Olden, K.2
Yamada, K.3
-
117
-
-
77951110744
-
Optimization of phenyl-substituted benzimidazole carboxamide poly(ADP-ribose) polymerase inhibitors: Identification of (S)-2-(2-fluoro-4- (pyrrolidin-2-yl)phenyl)-1H-benzimidazole-4-carboxamide (A-966492), a highly potent and efficacious inhibitor
-
Penning, T. et al. Optimization of phenyl-substituted benzimidazole carboxamide poly(ADP-ribose) polymerase inhibitors: identification of (S)-2-(2-fluoro-4-(pyrrolidin-2-yl)phenyl)-1H-benzimidazole-4-carboxamide (A-966492), a highly potent and efficacious inhibitor. J. Med. Chem. 53, 3142-3153 (2010
-
(2010)
J. Med. Chem.
, vol.53
, pp. 3142-3153
-
-
Penning, T.1
-
118
-
-
84891052763
-
Beyond DNA repair: Additional functions of PARP-1 in cancer
-
Alice, N. W. & Eddy, S. Y. Beyond, DNA repair: additional functions of PARP-1 in cancer. Front. Oncol. 3, 290 (2013
-
(2013)
Front. Oncol.
, vol.3
, pp. 290
-
-
Alice, N.W.1
Eddy, S.Y.2
-
119
-
-
84855895036
-
Activator-induced spread of poly(ADP-ribose) polymerase promotes nucleosome loss at Hsp70
-
Petesch, S. & Lis, J. Activator-induced spread of poly(ADP-ribose) polymerase promotes nucleosome loss at Hsp70. Mol. Cell 45, 64-74 (2012
-
(2012)
Mol. Cell
, vol.45
, pp. 64-74
-
-
Petesch, S.1
Lis, J.2
-
120
-
-
0033580856
-
PARP-2, A novel mammalian DNA damage-dependent poly(ADP-ribose) polymerase
-
Ame, J. et al. PARP-2, A novel mammalian DNA damage-dependent poly(ADP-ribose) polymerase. J. Biol. Chem. 274, 17860-17868 (1999
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 17860-17868
-
-
Ame, J.1
-
121
-
-
77950915348
-
PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNA
-
Loseva, O. et al. PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNA. J. Biol. Chem. 285, 8054-8060 (2010
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 8054-8060
-
-
Loseva, O.1
-
122
-
-
79952599748
-
Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression
-
Boehler, C. et al. Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression. Proc. Natl Acad. Sci. USA 108, 2783-2788 (2011
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 2783-2788
-
-
Boehler, C.1
-
123
-
-
0032553473
-
Tankyrase a poly(ADP-ribose) polymerase at human telomeres
-
Smith, S., Giriat, I., Schmitt, A. & de Lange, T. Tankyrase, a poly(ADP-ribose) polymerase at human telomeres. Science 282, 1484-1487 (1998
-
(1998)
Science
, vol.282
, pp. 1484-1487
-
-
Smith, S.1
Giriat, I.2
Schmitt, A.3
De Lange, T.4
-
124
-
-
0034687248
-
Tankyrase promotes telomere elongation in human cells
-
Smith, S. & de Lange, T. Tankyrase promotes telomere elongation in human cells. Curr. Biol. 10, 1299-1302 (2000
-
(2000)
Curr. Biol.
, vol.10
, pp. 1299-1302
-
-
Smith, S.1
De Lange, T.2
-
125
-
-
70349695861
-
Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling
-
Huang, S.-M. A. et al. Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling. Nature 461, 614-620 (2009
-
(2009)
Nature
, vol.461
, pp. 614-620
-
-
Huang, S.-M.A.1
-
126
-
-
84876935501
-
Proteasome regulation by ADP-ribosylation
-
Cho-Park, P. & Steller, H. Proteasome regulation by ADP-ribosylation. Cell 153, 614-627 (2013
-
(2013)
Cell
, vol.153
, pp. 614-627
-
-
Cho-Park, P.1
Steller, H.2
-
127
-
-
85047693635
-
Tankyrase-1 polymerization of poly(ADP-ribose) is required for spindle structure and function
-
Chang, P., Coughlin, M. & Mitchison, T. Tankyrase-1 polymerization of poly(ADP-ribose) is required for spindle structure and function. Nature Cell Biol. 7, 1133-1139 (2005
-
(2005)
Nature Cell Biol.
, vol.7
, pp. 1133-1139
-
-
Chang, P.1
Coughlin, M.2
Mitchison, T.3
-
128
-
-
0036132673
-
Role for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeres
-
Cook, B., Dynek, J., Chang, W., Shostak, G. & Smith, S. Role for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeres. Mol. Cell. Biol. 22, 332-342 (2002).
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 332-342
-
-
Cook, B.1
Dynek, J.2
Chang, W.3
Shostak, G.4
Smith, S.5
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