-
1
-
-
79956300649
-
Toll-like receptors and their crosstalk with other innate receptors in infection and immunity
-
Kawai, T., and S. Akira. 2011. Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity 34: 637-650.
-
(2011)
Immunity
, vol.34
, pp. 637-650
-
-
Kawai, T.1
Akira, S.2
-
2
-
-
84862855875
-
Nucleic acid sensing at the interface between innate and adaptive immunity in vaccination
-
Desmet, C. J., and K. J. Ishii. 2012. Nucleic acid sensing at the interface between innate and adaptive immunity in vaccination. Nat. Rev. Immunol. 12: 479-491.
-
(2012)
Nat. Rev. Immunol.
, vol.12
, pp. 479-491
-
-
Desmet, C.J.1
Ishii, K.J.2
-
3
-
-
84896958063
-
Innate immune sensing and signaling of cytosolic nucleic acids
-
Wu, J., and Z. J. Chen. 2014. Innate immune sensing and signaling of cytosolic nucleic acids. Annu. Rev. Immunol. 32: 461-488.
-
(2014)
Annu. Rev. Immunol.
, vol.32
, pp. 461-488
-
-
Wu, J.1
Chen, Z.J.2
-
4
-
-
84882348691
-
Nucleic acid driven sterile inflammation
-
Ablasser, A., C. Hertrich, R. Waßermann, and V. Hornung. 2013. Nucleic acid driven sterile inflammation. Clin. Immunol. 147: 207-215.
-
(2013)
Clin. Immunol.
, vol.147
, pp. 207-215
-
-
Ablasser, A.1
Hertrich, C.2
Waßermann, R.3
Hornung, V.4
-
5
-
-
77649152255
-
Autoimmunity and the clearance of dead cells
-
Nagata, S., R. Hanayama, and K. Kawane. 2010. Autoimmunity and the clearance of dead cells. Cell 140: 619-630.
-
(2010)
Cell
, vol.140
, pp. 619-630
-
-
Nagata, S.1
Hanayama, R.2
Kawane, K.3
-
6
-
-
50949089311
-
Erythroblastic islands: Niches for erythropoiesis
-
Chasis, J. A., and N. Mohandas. 2008. Erythroblastic islands: niches for erythropoiesis. Blood 112: 470-478.
-
(2008)
Blood
, vol.112
, pp. 470-478
-
-
Chasis, J.A.1
Mohandas, N.2
-
7
-
-
12344290452
-
Lethal anemia caused by interferon-beta produced in mouse embryos carrying undigested DNA
-
Yoshida, H., Y. Okabe, K. Kawane, H. Fukuyama, and S. Nagata. 2005. Lethal anemia caused by interferon-beta produced in mouse embryos carrying undigested DNA. Nat. Immunol. 6: 49-56.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 49-56
-
-
Yoshida, H.1
Okabe, Y.2
Kawane, K.3
Fukuyama, H.4
Nagata, S.5
-
8
-
-
0035947178
-
Requirement of DNase II for definitive erythropoiesis in the mouse fetal liver
-
Kawane, K., H. Fukuyama, G. Kondoh, J. Takeda, Y. Ohsawa, Y. Uchiyama, and S. Nagata. 2001. Requirement of DNase II for definitive erythropoiesis in the mouse fetal liver. Science 292: 1546-1549.
-
(2001)
Science
, vol.292
, pp. 1546-1549
-
-
Kawane, K.1
Fukuyama, H.2
Kondoh, G.3
Takeda, J.4
Ohsawa, Y.5
Uchiyama, Y.6
Nagata, S.7
-
9
-
-
33750465224
-
Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages
-
Kawane, K., M. Ohtani, K. Miwa, T. Kizawa, Y. Kanbara, Y. Yoshioka, H. Yoshikawa, and S. Nagata. 2006. Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages. Nature 443: 998-1002.
-
(2006)
Nature
, vol.443
, pp. 998-1002
-
-
Kawane, K.1
Ohtani, M.2
Miwa, K.3
Kizawa, T.4
Kanbara, Y.5
Yoshioka, Y.6
Yoshikawa, H.7
Nagata, S.8
-
10
-
-
78650606709
-
Cytokine-dependent but acquired immunity-independent arthritis caused by DNA escaped from degradation
-
Kawane, K., H. Tanaka, Y. Kitahara, S. Shimaoka, and S. Nagata. 2010. Cytokine-dependent but acquired immunity-independent arthritis caused by DNA escaped from degradation. Proc. Natl. Acad. Sci. USA 107: 19432-19437.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 19432-19437
-
-
Kawane, K.1
Tanaka, H.2
Kitahara, Y.3
Shimaoka, S.4
Nagata, S.5
-
11
-
-
49549100511
-
Trex1 prevents cell-intrinsic initiation of autoimmunity
-
Stetson, D. B., J. S. Ko, T. Heidmann, and R. Medzhitov. 2008. Trex1 prevents cell-intrinsic initiation of autoimmunity. Cell 134: 587-598.
-
(2008)
Cell
, vol.134
, pp. 587-598
-
-
Stetson, D.B.1
Ko, J.S.2
Heidmann, T.3
Medzhitov, R.4
-
12
-
-
80052164116
-
Cytoplasmic DNA innate immune pathways
-
Barber, G. N. 2011. Cytoplasmic DNA innate immune pathways. Immunol. Rev. 243: 99-108.
-
(2011)
Immunol. Rev.
, vol.243
, pp. 99-108
-
-
Barber, G.N.1
-
13
-
-
77951260924
-
The role of pattern-recognition receptors in innate immunity: Update on toll-like receptors
-
Kawai, T., and S. Akira. 2010. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat. Immunol. 11: 373-384.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 373-384
-
-
Kawai, T.1
Akira, S.2
-
14
-
-
27944453599
-
Toll-like receptor-independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation
-
Okabe, Y., K. Kawane, S. Akira, T. Taniguchi, and S. Nagata. 2005. Toll-like receptor-independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation. J. Exp. Med. 202: 1333-1339.
-
(2005)
J. Exp. Med.
, vol.202
, pp. 1333-1339
-
-
Okabe, Y.1
Kawane, K.2
Akira, S.3
Taniguchi, T.4
Nagata, S.5
-
15
-
-
30444450839
-
Recognition of cytosolic DNA activates an IRF3-dependent innate immune response
-
Stetson, D. B., and R. Medzhitov. 2006. Recognition of cytosolic DNA activates an IRF3-dependent innate immune response. Immunity 24: 93-103.
-
(2006)
Immunity
, vol.24
, pp. 93-103
-
-
Stetson, D.B.1
Medzhitov, R.2
-
16
-
-
53349178089
-
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
-
Ishikawa, H., and G. N. Barber. 2008. STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling. Nature 455: 674-678.
-
(2008)
Nature
, vol.455
, pp. 674-678
-
-
Ishikawa, H.1
Barber, G.N.2
-
17
-
-
77954070545
-
c-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response
-
Woodward, J. J., A. T. Iavarone, and D. A. Portnoy. 2010. c-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response. Science 328: 1703-1705.
-
(2010)
Science
, vol.328
, pp. 1703-1705
-
-
Woodward, J.J.1
Iavarone, A.T.2
Portnoy, D.A.3
-
18
-
-
80054966913
-
STING is a direct innate immune sensor of cyclic di-GMP
-
Burdette, D. L., K. M. Monroe, K. Sotelo-Troha, J. S. Iwig, B. Eckert, M. Hyodo, Y. Hayakawa, and R. E. Vance. 2011. STING is a direct innate immune sensor of cyclic di-GMP. Nature 478: 515-518.
-
(2011)
Nature
, vol.478
, pp. 515-518
-
-
Burdette, D.L.1
Monroe, K.M.2
Sotelo-Troha, K.3
Iwig, J.S.4
Eckert, B.5
Hyodo, M.6
Hayakawa, Y.7
Vance, R.E.8
-
19
-
-
84873711885
-
Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway
-
Sun, L., J. Wu, F. Du, X. Chen, and Z. J. Chen. 2013. Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway. Science 339: 786-791.
-
(2013)
Science
, vol.339
, pp. 786-791
-
-
Sun, L.1
Wu, J.2
Du, F.3
Chen, X.4
Chen, Z.J.5
-
20
-
-
84873724533
-
Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA
-
Wu, J., L. Sun, X. Chen, F. Du, H. Shi, C. Chen, and Z. J. Chen. 2013. Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA. Science 339: 826-830.
-
(2013)
Science
, vol.339
, pp. 826-830
-
-
Wu, J.1
Sun, L.2
Chen, X.3
Du, F.4
Shi, H.5
Chen, C.6
Chen, Z.J.7
-
21
-
-
84878572947
-
The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING
-
Diner, E. J., D. L. Burdette, S. C. Wilson, K. M. Monroe, C. A. Kellenberger, M. Hyodo, Y. Hayakawa, M. C. Hammond, and R. E. Vance. 2013. The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING. Cell Reports 3: 1355-1361.
-
(2013)
Cell Reports
, vol.3
, pp. 1355-1361
-
-
Diner, E.J.1
Burdette, D.L.2
Wilson, S.C.3
Monroe, K.M.4
Kellenberger, C.A.5
Hyodo, M.6
Hayakawa, Y.7
Hammond, M.C.8
Vance, R.E.9
-
22
-
-
84878592773
-
Structure of human cGAS reveals a conserved family of second-messenger enzymes in innate immunity
-
Kranzusch, P. J., A. S.-Y. Lee, J. M. Berger, and J. A. Doudna. 2013. Structure of human cGAS reveals a conserved family of second-messenger enzymes in innate immunity. Cell Reports 3: 1362-1368.
-
(2013)
Cell Reports
, vol.3
, pp. 1362-1368
-
-
Kranzusch, P.J.1
Lee, A.S.-Y.2
Berger, J.M.3
Doudna, J.A.4
-
23
-
-
84882815198
-
Structure-function analysis of STING activation by c[G(2',5')pA(3',5')p] and targeting by antiviral DMXAA
-
Gao, P., M. Ascano, T. Zillinger, W. Wang, P. Dai, A. A. Serganov, B. L. Gaffney, S. Shuman, R. A. Jones, L. Deng, et al. 2013. Structure-function analysis of STING activation by c[G(2',5')pA(3',5')p] and targeting by antiviral DMXAA. Cell 154: 748-762.
-
(2013)
Cell
, vol.154
, pp. 748-762
-
-
Gao, P.1
Ascano, M.2
Zillinger, T.3
Wang, W.4
Dai, P.5
Serganov, A.A.6
Gaffney, B.L.7
Shuman, S.8
Jones, R.A.9
Deng, L.10
-
24
-
-
70349943834
-
STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
-
Ishikawa, H., Z. Ma, and G. N. Barber. 2009. STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity. Nature 461: 788-792.
-
(2009)
Nature
, vol.461
, pp. 788-792
-
-
Ishikawa, H.1
Ma, Z.2
Barber, G.N.3
-
25
-
-
84856301080
-
Autoimmunity initiates in nonhematopoietic cells and progresses via lymphocytes in an interferon-dependent autoimmune disease
-
Gall, A., P. Treuting, K. B. Elkon, Y.-M. Loo, M. Gale, Jr., G. N. Barber, and D. B. Stetson. 2012. Autoimmunity initiates in nonhematopoietic cells and progresses via lymphocytes in an interferon-dependent autoimmune disease. Immunity 36: 120-131.
-
(2012)
Immunity
, vol.36
, pp. 120-131
-
-
Gall, A.1
Treuting, P.2
Elkon, K.B.3
Loo, Y.-M.4
Gale, M.5
Barber, G.N.6
Stetson, D.B.7
-
26
-
-
84882896267
-
Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses
-
Gao, D., J. Wu, Y.-T. Wu, F. Du, C. Aroh, N. Yan, L. Sun, and Z. J. Chen. 2013. Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses. Science 341: 903-906.
-
(2013)
Science
, vol.341
, pp. 903-906
-
-
Gao, D.1
Wu, J.2
Wu, Y.-T.3
Du, F.4
Aroh, C.5
Yan, N.6
Sun, L.7
Chen, Z.J.8
-
27
-
-
84884675857
-
Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects
-
Li, X. D., J. Wu, D. Gao, H. Wang, L. Sun, and Z. J. Chen. 2013. Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects. Science 341: 1390-1394.
-
(2013)
Science
, vol.341
, pp. 1390-1394
-
-
Li, X.D.1
Wu, J.2
Gao, D.3
Wang, H.4
Sun, L.5
Chen, Z.J.6
-
28
-
-
84869794842
-
STING manifests self DNA-dependent inflammatory disease
-
Ahn, J., D. Gutman, S. Saijo, and G. N. Barber. 2012. STING manifests self DNA-dependent inflammatory disease. Proc. Natl. Acad. Sci. USA 109: 19386-19391.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 19386-19391
-
-
Ahn, J.1
Gutman, D.2
Saijo, S.3
Barber, G.N.4
-
29
-
-
0034046944
-
Plat-E: An efficient and stable system for transient packaging of retroviruses
-
Morita, S., T. Kojima, and T. Kitamura. 2000. Plat-E: an efficient and stable system for transient packaging of retroviruses. Gene Ther. 7: 1063-1066.
-
(2000)
Gene Ther
, vol.7
, pp. 1063-1066
-
-
Morita, S.1
Kojima, T.2
Kitamura, T.3
-
30
-
-
0142227052
-
Retrovirus-mediated gene transfer and expression cloning: Powerful tools in functional genomics
-
Kitamura, T., Y. Koshino, F. Shibata, T. Oki, H. Nakajima, T. Nosaka, and H. Kumagai. 2003. Retrovirus-mediated gene transfer and expression cloning: powerful tools in functional genomics. Exp. Hematol. 31: 1007-1014.
-
(2003)
Exp. Hematol.
, vol.31
, pp. 1007-1014
-
-
Kitamura, T.1
Koshino, Y.2
Shibata, F.3
Oki, T.4
Nakajima, H.5
Nosaka, T.6
Kumagai, H.7
-
31
-
-
36248944555
-
Identification of Tim4 as a phosphatidylserine receptor
-
Miyanishi, M., K. Tada, M. Koike, Y. Uchiyama, T. Kitamura, and S. Nagata. 2007. Identification of Tim4 as a phosphatidylserine receptor. Nature 450: 435-439.
-
(2007)
Nature
, vol.450
, pp. 435-439
-
-
Miyanishi, M.1
Tada, K.2
Koike, M.3
Uchiyama, Y.4
Kitamura, T.5
Nagata, S.6
-
32
-
-
84896501141
-
Tim4- and MerTK-mediated engulfment of apoptotic cells by mouse resident peritoneal macrophages
-
Nishi, C., S. Toda, K. Segawa, and S. Nagata. 2014. Tim4- and MerTK-mediated engulfment of apoptotic cells by mouse resident peritoneal macrophages. Mol. Cell. Biol. 34: 1512-1520.
-
(2014)
Mol. Cell. Biol.
, vol.34
, pp. 1512-1520
-
-
Nishi, C.1
Toda, S.2
Segawa, K.3
Nagata, S.4
-
33
-
-
4143094790
-
Increased cytotoxicity of soluble Fas ligand by fusing isoleucine zipper motif
-
Shiraishi, T., K. Suzuyama, H. Okamoto, T. Mineta, K. Tabuchi, K. Nakayama, Y. Shimizu, J. Tohma, T. Ogihara, H. Naba, et al. 2004. Increased cytotoxicity of soluble Fas ligand by fusing isoleucine zipper motif. Biochem. Biophys. Res. Commun. 322: 197-202.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.322
, pp. 197-202
-
-
Shiraishi, T.1
Suzuyama, K.2
Okamoto, H.3
Mineta, T.4
Tabuchi, K.5
Nakayama, K.6
Shimizu, Y.7
Tohma, J.8
Ogihara, T.9
Naba, H.10
-
34
-
-
0024991898
-
pEF-BOS, a powerful mammalian expression vector
-
Mizushima, S., and S. Nagata. 1990. pEF-BOS, a powerful mammalian expression vector. Nucleic Acids Res. 18: 5322.
-
(1990)
Nucleic Acids Res
, vol.18
, pp. 5322
-
-
Mizushima, S.1
Nagata, S.2
-
35
-
-
84873729095
-
Multiplex genome engineering using CRISPR/Cas systems
-
Cong, L., F. A. Ran, D. Cox, S. Lin, R. Barretto, N. Habib, P. D. Hsu, X. Wu, W. Jiang, L. A. Marraffini, and F. Zhang. 2013. Multiplex genome engineering using CRISPR/Cas systems. Science 339: 819-823.
-
(2013)
Science
, vol.339
, pp. 819-823
-
-
Cong, L.1
Ran, F.A.2
Cox, D.3
Lin, S.4
Barretto, R.5
Habib, N.6
Hsu, P.D.7
Wu, X.8
Jiang, W.9
Marraffini, L.A.10
Zhang, F.11
-
36
-
-
59949083330
-
A novel method to determine the engulfment of apoptotic cells by macrophages using pHrodo succinimidyl ester
-
Miksa, M., H. Komura, R. Wu, K. G. Shah, and P. Wang. 2009. A novel method to determine the engulfment of apoptotic cells by macrophages using pHrodo succinimidyl ester. J. Immunol. Methods 342: 71-77.
-
(2009)
J. Immunol. Methods
, vol.342
, pp. 71-77
-
-
Miksa, M.1
Komura, H.2
Wu, R.3
Shah, K.G.4
Wang, P.5
-
37
-
-
84856789589
-
Two-step engulfment of apoptotic cells
-
Toda, S., R. Hanayama, and S. Nagata. 2012. Two-step engulfment of apoptotic cells. Mol. Cell. Biol. 32: 118-125.
-
(2012)
Mol. Cell. Biol.
, vol.32
, pp. 118-125
-
-
Toda, S.1
Hanayama, R.2
Nagata, S.3
-
38
-
-
73949085808
-
Fetal calf serum contains heat-stable nucleases that degrade neutrophil extracellular traps
-
von Köckritz-Blickwede, M., O. A. Chow, and V. Nizet. 2009. Fetal calf serum contains heat-stable nucleases that degrade neutrophil extracellular traps. Blood 114: 5245-5246.
-
(2009)
Blood
, vol.114
, pp. 5245-5246
-
-
Von Köckritz-Blickwede, M.1
Chow, O.A.2
Nizet, V.3
-
39
-
-
84934435958
-
Extraction and quantification of adenosine triphosphate in mammalian tissues and cells
-
Chida, J., and H. Kido. 2014. Extraction and quantification of adenosine triphosphate in mammalian tissues and cells. Methods Mol. Biol. 1098: 21-32.
-
(2014)
Methods Mol. Biol.
, vol.1098
, pp. 21-32
-
-
Chida, J.1
Kido, H.2
-
40
-
-
0034809827
-
PACT, a double-stranded RNA binding protein acts as a positive regulator for type I interferon gene induced by Newcastle disease virus
-
Iwamura, T., M. Yoneyama, N. Koizumi, Y. Okabe, H. Namiki, C. E. Samuel, and T. Fujita. 2001. PACT, a double-stranded RNA binding protein acts as a positive regulator for type I interferon gene induced by Newcastle disease virus. Biochem. Biophys. Res. Commun. 282: 515-523.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.282
, pp. 515-523
-
-
Iwamura, T.1
Yoneyama, M.2
Koizumi, N.3
Okabe, Y.4
Namiki, H.5
Samuel, C.E.6
Fujita, T.7
-
41
-
-
0346025621
-
Deoxyribonuclease II is a lysosomal barrier to transfection
-
Howell, D. P.-G., R. J. Krieser, A. Eastman, and M. A. Barry. 2003. Deoxyribonuclease II is a lysosomal barrier to transfection. Mol. Ther. 8: 957-963.
-
(2003)
Mol. Ther.
, vol.8
, pp. 957-963
-
-
Howell, D.P.-G.1
Krieser, R.J.2
Eastman, A.3
Barry, M.A.4
-
42
-
-
80052662208
-
MPYS is required for IFN response factor 3 activation and type I IFN production in the response of cultured phagocytes to bacterial second messengers cyclic-di-AMP and cyclic-di-GMP
-
Jin, L., K. K. Hill, H. Filak, J. Mogan, H. Knowles, B. Zhang, A.-L. Perraud, J. C. Cambier, and L. L. Lenz. 2011. MPYS is required for IFN response factor 3 activation and type I IFN production in the response of cultured phagocytes to bacterial second messengers cyclic-di-AMP and cyclic-di-GMP. J. Immunol. 187: 2595-2601.
-
(2011)
J. Immunol.
, vol.187
, pp. 2595-2601
-
-
Jin, L.1
Hill, K.K.2
Filak, H.3
Mogan, J.4
Knowles, H.5
Zhang, B.6
Perraud, A.-L.7
Cambier, J.C.8
Lenz, L.L.9
-
43
-
-
66649109939
-
ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization
-
Sun, W., Y. Li, L. Chen, H. Chen, F. You, X. Zhou, Y. Zhou, Z. Zhai, D. Chen, and Z. Jiang. 2009. ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization. Proc. Natl. Acad. Sci. USA 106: 8653-8658.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 8653-8658
-
-
Sun, W.1
Li, Y.2
Chen, L.3
Chen, H.4
You, F.5
Zhou, X.6
Zhou, Y.7
Zhai, Z.8
Chen, D.9
Jiang, Z.10
-
44
-
-
84880508067
-
Cyclic GMP-AMP containing mixed phosphodiester linkages is an endogenous high-affinity ligand for STING
-
Zhang, X., H. Shi, J. Wu, X. Zhang, L. Sun, C. Chen, and Z. J. Chen. 2013. Cyclic GMP-AMP containing mixed phosphodiester linkages is an endogenous high-affinity ligand for STING. Mol. Cell 51: 226-235.
-
(2013)
Mol. Cell
, vol.51
, pp. 226-235
-
-
Zhang, X.1
Shi, H.2
Wu, J.3
Zhang, X.4
Sun, L.5
Chen, C.6
Chen, Z.J.7
-
45
-
-
84892449850
-
Direct, interferon-independent activation of the CXCL10 promoter by NF-κB and interferon regulatory factor 3 during hepatitis C virus infection
-
Brownell, J., J. Bruckner, J. Wagoner, E. Thomas, Y. M. Loo, M. Gale, Jr., T. J. Liang, and S. J. Polyak. 2014. Direct, interferon-independent activation of the CXCL10 promoter by NF-κB and interferon regulatory factor 3 during hepatitis C virus infection. J. Virol. 88: 1582-1590.
-
(2014)
J. Virol.
, vol.88
, pp. 1582-1590
-
-
Brownell, J.1
Bruckner, J.2
Wagoner, J.3
Thomas, E.4
Loo, Y.M.5
Gale, M.6
Liang, T.J.7
Polyak, S.J.8
-
46
-
-
79955542915
-
A diverse range of gene products are effectors of the type I interferon antiviral response
-
Schoggins, J. W., S. J. Wilson, M. Panis, M. Y. Murphy, C. T. Jones, P. Bieniasz, and C. M. Rice. 2011. A diverse range of gene products are effectors of the type I interferon antiviral response. Nature 472: 481-485.
-
(2011)
Nature
, vol.472
, pp. 481-485
-
-
Schoggins, J.W.1
Wilson, S.J.2
Panis, M.3
Murphy, M.Y.4
Jones, C.T.5
Bieniasz, P.6
Rice, C.M.7
-
47
-
-
84872479464
-
Enzyme replacement therapy for lysosomal diseases: Lessons from 20 years of experience and remaining challenges
-
Desnick, R. J., and E. H. Schuchman. 2012. Enzyme replacement therapy for lysosomal diseases: lessons from 20 years of experience and remaining challenges. Annu. Rev. Genomics Hum. Genet. 13: 307-335.
-
(2012)
Annu. Rev. Genomics Hum. Genet.
, vol.13
, pp. 307-335
-
-
Desnick, R.J.1
Schuchman, E.H.2
-
48
-
-
84905123345
-
OAS proteins and cGAS: Unifying concepts in sensing and responding to cytosolic nucleic acids
-
Hornung, V., R. Hartmann, A. Ablasser, and K.-P. Hopfner. 2014. OAS proteins and cGAS: unifying concepts in sensing and responding to cytosolic nucleic acids. Nat. Rev. Immunol. 14: 521-528.
-
(2014)
Nat. Rev. Immunol.
, vol.14
, pp. 521-528
-
-
Hornung, V.1
Hartmann, R.2
Ablasser, A.3
Hopfner, K.-P.4
-
49
-
-
84877144293
-
DNA sensing unchained
-
Ablasser, A., and V. Hornung. 2013. DNA sensing unchained. Cell Res. 23: 585-587.
-
(2013)
Cell Res
, vol.23
, pp. 585-587
-
-
Ablasser, A.1
Hornung, V.2
-
50
-
-
84863009492
-
Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding
-
Ouyang, S., X. Song, Y. Wang, H. Ru, N. Shaw, Y. Jiang, F. Niu, Y. Zhu, W. Qiu, K. Parvatiyar, et al. 2012. Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding. Immunity 36: 1073-1086.
-
(2012)
Immunity
, vol.36
, pp. 1073-1086
-
-
Ouyang, S.1
Song, X.2
Wang, Y.3
Ru, H.4
Shaw, N.5
Jiang, Y.6
Niu, F.7
Zhu, Y.8
Qiu, W.9
Parvatiyar, K.10
-
51
-
-
84863726252
-
Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system
-
Shu, C., G. Yi, T. Watts, C. C. Kao, and P. Li. 2012. Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system. Nat. Struct. Mol. Biol. 19: 722-724.
-
(2012)
Nat. Struct. Mol. Biol.
, vol.19
, pp. 722-724
-
-
Shu, C.1
Yi, G.2
Watts, T.3
Kao, C.C.4
Li, P.5
-
52
-
-
84879385334
-
cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING
-
Ablasser, A., M. Goldeck, T. Cavlar, T. Deimling, G. Witte, I. Röhl, K.-P. Hopfner, J. Ludwig, and V. Hornung. 2013. cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING. Nature 498: 380-384.
-
(2013)
Nature
, vol.498
, pp. 380-384
-
-
Ablasser, A.1
Goldeck, M.2
Cavlar, T.3
Deimling, T.4
Witte, G.5
Röhl, I.6
Hopfner, K.-P.7
Ludwig, J.8
Hornung, V.9
-
53
-
-
84879408976
-
Structural mechanism of cytosolic DNA sensing by cGAS
-
Civril, F., T. Deimling, C. C. de Oliveira Mann, A. Ablasser, M. Moldt, G. Witte, V. Hornung, and K.-P. Hopfner. 2013. Structural mechanism of cytosolic DNA sensing by cGAS. Nature 498: 332-337.
-
(2013)
Nature
, vol.498
, pp. 332-337
-
-
Civril, F.1
Deimling, T.2
De Oliveira Mann, C.C.3
Ablasser, A.4
Moldt, M.5
Witte, G.6
Hornung, V.7
Hopfner, K.-P.8
-
54
-
-
71849105150
-
A novel IFN regulatory factor 3-dependent pathway activated by trypanosomes triggers IFN-beta in macrophages and fibroblasts
-
Chessler, A. D. C., L. R. P. Ferreira, T. H. Chang, K. A. Fitzgerald, and B. A. Burleigh. 2008. A novel IFN regulatory factor 3-dependent pathway activated by trypanosomes triggers IFN-beta in macrophages and fibroblasts. J. Immunol. 181: 7917-7924.
-
(2008)
J. Immunol.
, vol.181
, pp. 7917-7924
-
-
Chessler, A.D.C.1
Ferreira, L.R.P.2
Chang, T.H.3
Fitzgerald, K.A.4
Burleigh, B.A.5
-
55
-
-
84856020851
-
Streptococcus pneumoniae stimulates a STING- and IFN regulatory factor 3-dependent type I IFN production in macrophages, which regulates RANTES production in macrophages, cocultured alveolar epithelial cells, and mouse lungs
-
Koppe, U., K. Högner, J. M. Doehn, H. C. Müller, M. Witzenrath, B. Gutbier, S. Bauer, T. Pribyl, S. Hammerschmidt, J. Lohmeyer, et al. 2012. Streptococcus pneumoniae stimulates a STING- and IFN regulatory factor 3-dependent type I IFN production in macrophages, which regulates RANTES production in macrophages, cocultured alveolar epithelial cells, and mouse lungs. J. Immunol. 188: 811-817.
-
(2012)
J. Immunol.
, vol.188
, pp. 811-817
-
-
Koppe, U.1
Högner, K.2
Doehn, J.M.3
Müller, H.C.4
Witzenrath, M.5
Gutbier, B.6
Bauer, S.7
Pribyl, T.8
Hammerschmidt, S.9
Lohmeyer, J.10
-
56
-
-
80054122543
-
Dissection of a type I interferon pathway in controlling bacterial intracellular infection in mice
-
Lippmann, J., H. C. Müller, J. Naujoks, C. Tabeling, S. Shin, M. Witzenrath, K. Hellwig, C. J. Kirschning, G. A. Taylor, W. Barchet, et al. 2011. Dissection of a type I interferon pathway in controlling bacterial intracellular infection in mice. Cell. Microbiol. 13: 1668-1682.
-
(2011)
Cell. Microbiol.
, vol.13
, pp. 1668-1682
-
-
Lippmann, J.1
Müller, H.C.2
Naujoks, J.3
Tabeling, C.4
Shin, S.5
Witzenrath, M.6
Hellwig, K.7
Kirschning, C.J.8
Taylor, G.A.9
Barchet, W.10
-
57
-
-
80051880722
-
Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome
-
Sharma, S., R. B. DeOliveira, P. Kalantari, P. Parroche, N. Goutagny, Z. Jiang, J. Chan, D. C. Bartholomeu, F. Lauw, J. P. Hall, et al. 2011. Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome. Immunity 35: 194-207.
-
(2011)
Immunity
, vol.35
, pp. 194-207
-
-
Sharma, S.1
DeOliveira, R.B.2
Kalantari, P.3
Parroche, P.4
Goutagny, N.5
Jiang, Z.6
Chan, J.7
Bartholomeu, D.C.8
Lauw, F.9
Hall, J.P.10
|