Sensitive detection of chromatin-altering polymorphisms reveals autoimmune disease mechanisms

Nature Methods

Volumn 12, Issue 5, 2015, Pages 458-464

  Del Rosario, Ricardo Cruz Herrera ^a   Poschmann, Jeremie ^a   Rouam, Sigrid Laure ^a,e   Png, Eileen ^a   Khor, Chiea Chuen ^a,b,c   Hibberd, Martin Lloyd ^a,d   Prabhakar, Shyam ^a  

^a GENOME INSTITUTE OF SINGAPORE   (Singapore)

^b SINGAPORE EYE RESEARCH INSTITUTE   (Singapore)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^e PROCTER AND GAMBLE COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE; GENETIC MARKER; TRANSCRIPTOME;

ALLELIC IMBALANCE; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNITY; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; ENHANCER REGION; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC CORRELATION; GENETIC VARIABILITY; GENOTYPE; HISTONE ACETYLATION; HUMAN; HUMAN CELL; LARGE SCALE PRODUCTION; LYMPHOBLASTOID CELL LINE; MOLECULAR PATHOLOGY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; QUANTITATIVE TRAIT LOCUS; QUANTITATIVE TRAIT LOCUS MAPPING; REGULATORY SEQUENCE; SINGLE NUCLEOTIDE POLYMORPHISM; VALIDATION STUDY; ACETYLATION; ALLELE; CELL LINE; GENE EXPRESSION REGULATION; GENETIC MARKER; GENETICS; METABOLISM;

ACETYLATION; ALLELES; CELL LINE; GENE EXPRESSION REGULATION; GENETIC MARKERS; GENOTYPE; HISTONES; HUMANS; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT LOCI; TRANSCRIPTOME;

EID: 84928924946     PISSN: 15487091     EISSN: 15487105     Source Type: Journal    
DOI: 10.1038/nmeth.3326     Document Type: Article

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