Wogonin induces apoptosis and endoplasmic reticulum stress in HL-60 leukemia cells through inhibition of the PI3K-AKT signaling pathway

Oncology Reports

Volumn 33, Issue 6, 2015, Pages 3146-3154

  Hu, Chengjun ^a   Xu, Maozhong ^a   Qin, Rujuan ^a   Chen, Weifeng ^a   Xu, Xin ^a  

^a MEDICAL SCHOOL OF SOUTHEAST UNIVERSITY   (China)

Author keywords

Apoptosis; ER stress; HL 60 cells; PI3K AKT; Wogonin

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; ADENOVIRUS VECTOR; CASPASE; GLUCOSE REGULATED PROTEIN 78; GLUCOSE REGULATED PROTEIN 94; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2ALPHA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN IRE1; PROTEIN IRE1 ALPHA; PROTEIN KINASE B; PROTEIN PERK; UNCLASSIFIED DRUG; WOGONIN; FLAVANONE DERIVATIVE; ONCOPROTEIN; REACTIVE OXYGEN METABOLITE; TUMOR PROTEIN;

APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; DOSE RESPONSE; DRUG CYTOTOXICITY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; HL 60 LEUKEMIA CELL LINE; HUMAN; HUMAN CELL; LEUKEMIA; LEUKEMIA CELL; LEUKEMIA CELL LINE; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; CELL PROLIFERATION; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HL 60 CELL LINE; MULTIDRUG RESISTANCE; PATHOLOGY;

ANIMALS; APOPTOSIS; CELL PROLIFERATION; DRUG RESISTANCE, MULTIPLE; ENDOPLASMIC RETICULUM STRESS; FLAVANONES; GENE EXPRESSION REGULATION, LEUKEMIC; HL-60 CELLS; HUMANS; LEUKEMIA; NEOPLASM PROTEINS; ONCOGENE PROTEIN V-AKT; PHOSPHATIDYLINOSITOL 3-KINASES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84928901758     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2015.3896     Document Type: Article

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