MicroRNA in intervertebral disc degeneration

Cell Proliferation

Volumn 48, Issue 3, 2015, Pages 278-283

  Li, Zheng ^a   Yu, Xin ^a   Shen, Jianxiong ^a   Chan, Matthew T V ^b   Wu, William Ka Kei ^b  

^a PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; MICRORNA 10B;

APOPTOSIS; ARTICLE; BIOGENESIS; BONE REMODELING; CELL DEATH; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; ENZYME ACTIVATION; GENE EXPRESSION; GENE FUNCTION; GENE REGULATORY NETWORK; HUMAN; INTERVERTEBRAL DISK DEGENERATION; NONHUMAN; NUCLEUS PULPOSUS; CARTILAGE CELL; CELL DIFFERENTIATION; CELL MOTION; GENE EXPRESSION PROFILING; GENETIC EPIGENESIS; GENETICS; INTERVERTEBRAL DISK; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION;

APOPTOSIS; CELL DIFFERENTIATION; CELL MOVEMENT; CELL PROLIFERATION; CHONDROCYTES; EPIGENESIS, GENETIC; GENE EXPRESSION PROFILING; HUMANS; INTERVERTEBRAL DISC; INTERVERTEBRAL DISC DEGENERATION; MICRORNAS; SIGNAL TRANSDUCTION;

EID: 84928828613     PISSN: 09607722     EISSN: 13652184     Source Type: Journal    
DOI: 10.1111/cpr.12180     Document Type: Article

References (86)

1. Masuda K, Oegema TR Jr, An HS (2004) Growth factors and treatment of intervertebral disc degeneration. Spine (Phila Pa 1976) 29, 2757-2769.
2. Millecamps M, Tajerian M, Naso L, Sage EH, Stone LS (2012) Lumbar intervertebral disc degeneration associated with axial and radiating low back pain in ageing SPARC-null mice. Pain 153, 1167-1179.
3. Raj PP (2008) Intervertebral disc: anatomy-physiology-pathophysiology-treatment. Pain Pract. 8, 18-44.
4. Loreto C, Musumeci G, Castorina A, Martinez G (2011) Degenerative disc disease of herniated intervertebral discs is associated with extracellular matrix remodeling, vimentin-positive cells and cell death. Ann. Anat. 193, 156-162.
5. Adams MA, Roughley PJ (2006) What is intervertebral disc degeneration, and what causes it? Spine (Phila Pa 1976) 31, 2151-2161.
6. Furukawa T, Ito K, Nuka S, Hashimoto J, Takei H, Takahara M et al. (2009) Absence of biglycan accelerates the degenerative process in mouse intervertebral disc. Spine (Phila Pa 1976) 34, 911-917.
7. Mayer JE, Iatridis JC, Chan D, Qureshi SA, Gottesman O, Hecht AC (2013) Genetic polymorphisms associated with intervertebral disc degeneration. Spine J. 13, 299-317.
8. Li Z, Shen J, Wu WK, Yu X, Liang J, Qiu G et al. (2012) Leptin induces cyclin D1 expression and proliferation of human nucleus pulposus cells via JAK/STAT, PI3K/Akt and MEK/ERK pathways. PLoS ONE 7, e53176.
9. Li Z, Liang J, Wu WK, Yu X, Yu J, Weng X et al. (2014) Leptin activates RhoA/ROCK pathway to induce cytoskeleton remodeling in nucleus pulposus cells. Int. J. Mol. Sci. 15, 1176-1188.
10. Li Z, Shen J, Wu WK, Yu X, Liang J, Qiu G et al. (2013) The role of leptin on the organization and expression of cytoskeleton elements in nucleus pulposus cells. J. Orthop. Res. 31, 847-857.
11. Li Z, Lei H, Luo M, Wang Y, Dong L, Ma Y et al. (2015) DNA methylation downregulated mir-10b acts as a tumor suppressor in gastric cancer. Gastric Cancer 18, 43-54.
12. Brenner B, Hoshen MB, Purim O, David MB, Ashkenazi K, Marshak G et al. (2011) MicroRNAs as a potential prognostic factor in gastric cancer. World J. Gastroenterol. 17, 3976-3985.
13. Zheng F, Liao YJ, Cai MY, Liu YH, Liu TH, Chen SP et al. (2012) The putative tumour suppressor microRNA-124 modulates hepatocellular carcinoma cell aggressiveness by repressing ROCK2 and EZH2. Gut 61, 278-289.
14. Zhao H, Guo M, Zhao G, Ma Q, Ma B, Qiu X et al. (2012) miR-183 inhibits the metastasis of osteosarcoma via downregulation of the expression of Ezrin in F5M2 cells. Int. J. Mol. Med. 30, 1013-1020.
15. Malumbres M (2012) miRNAs and cancer: an epigenetics view. Mol. Aspects Med. 34, 863-74.
16. Liang W, Gao B, Fu P, Xu S, Qian Y, Fu Q. (2013) The miRNAs in the pathgenesis of osteosarcoma. Front. Biosci. (Landmark Ed.) 18, 788-794.
17. Farazi TA, Spitzer JI, Morozov P, Tuschl T (2011) miRNAs in human cancer. J. Pathol. 223, 102-115.
18. Fabbri M, Calin GA (2010) Epigenetics and miRNAs in human cancer. Adv. Genet. 70, 87-99.
19. Kozlowska E, Krzyzosiak WJ, Koscianska E (2013) Regulation of huntingtin gene expression by miRNA-137, -214, -148a, and their respective isomiRs. Int. J. Mol. Sci. 14, 16999-17016.
20. Ishikawa K, Ishikawa A, Shoji Y, Imai T (2014) A genotoxic stress-responsive miRNA, miR-574-3p, delays cell growth by suppressing the enhancer of rudimentary homolog gene in vitro. Int. J. Mol. Sci. 15, 2971-2990.
21. Fayyad-Kazan H, Bitar N, Najar M, Lewalle P, Fayyad-Kazan M, Badran R et al. (2013) Circulating miR-150 and miR-342 in plasma are novel potential biomarkers for acute myeloid leukemia. J. Transl. Med. 11, 31.
22. Bianchi N, Zuccato C, Finotti A, Lampronti I, Borgatti M, Gambari R. (2012) Involvement of miRNA in erythroid differentiation. Epigenomics 4, 51-65.
23. Dassow H, Aigner A (2013) MicroRNAs (miRNAs) in colorectal cancer: from aberrant expression towards therapy. Curr. Pharm. Des. 19, 1242-1252.
24. Marcinkowska M, Szymanski M, Krzyzosiak WJ, Kozlowski P (2011) Copy number variation of microRNA genes in the human genome. BMC Genom. 12, 183.
25. Papagiannakopoulos T, Kosik KS (2008) MicroRNAs: regulators of oncogenesis and stemness. BMC Med. 6, 15.
26. Sato F, Tsuchiya S, Meltzer SJ, Shimizu K (2011) MicroRNAs and epigenetics. FEBS J. 278, 1598-1609.
27. Nelson KM, Weiss GJ (2008) MicroRNAs and cancer: past, present, and potential future. Mol. Cancer Ther. 7, 3655-3660.
28. Han L, Witmer PD, Casey E, Valle D, Sukumar S (2007) DNA methylation regulates MicroRNA expression. Cancer Biol. Ther. 6, 1284-1288.
29. Chen Z, Wu J, Yang C, Fan P, Balazs L, Jiao Y et al. (2012) DiGeorge syndrome critical region 8 (DGCR8) protein-mediated microRNA biogenesis is essential for vascular smooth muscle cell development in mice. J. Biol. Chem. 287, 19018-19028.
30. Fan P, Chen Z, Tian P, Liu W, Jiao Y, Xue Y et al. (2013) miRNA biogenesis enzyme Drosha is required for vascular smooth muscle cell survival. PLoS ONE 8, e60888.
31. Fernandez-Hernando C, Ramirez CM, Goedeke L, Suarez Y (2013) MicroRNAs in metabolic disease. Arterioscler. Thromb. Vasc. Biol. 33, 178-185.
32. Grant JS, White K, Maclean MR, Baker AH (2013) MicroRNAs in pulmonary arterial remodeling. Cell. Mol. Life Sci. 70, 4479-94.
33. Rottiers V, Naar AM (2012) MicroRNAs in metabolism and metabolic disorders. Nat. Rev. Mol. Cell Biol. 13, 239-250.
34. Guancial EA, Bellmunt J, Yeh S, Rosenberg JE, Berman DM (2014) The evolving understanding of microRNA in bladder cancer. Urol. Oncol. 32(41), e31-e40.
35. Yoshino H, Seki N, Itesako T, Chiyomaru T, Nakagawa M, Enokida H. (2013) Aberrant expression of microRNAs in bladder cancer. Nat. Rev. Urol. 10, 396-404.
36. Kobayashi E, Hornicek FJ, Duan Z (2012) MicroRNA Involvement in Osteosarcoma. Sarcoma 2012, 359739.
37. Gillen AE, Gosalia N, Leir SH, Harris A (2011) MicroRNA regulation of expression of the cystic fibrosis transmembrane conductance regulator gene. Biochem. J. 438, 25-32.
38. Bou Kheir T, Futoma-Kazmierczak E, Jacobsen A, Krogh A, Bardram L, Hother C et al. (2011) miR-449 inhibits cell proliferation and is down-regulated in gastric cancer. Mol. Cancer. 10, 29.
39. Montag J, Hitt R, Opitz L, Schulz-Schaeffer WJ, Hunsmann G, Motzkus D. (2009) Upregulation of miRNA hsa-miR-342-3p in experimental and idiopathic prion disease. Mol. Neurodegener. 4, 36.
40. Wilfred BR, Wang WX, Nelson PT (2007) Energizing miRNA research: a review of the role of miRNAs in lipid metabolism, with a prediction that miR-103/107 regulates human metabolic pathways. Mol. Genet. Metab. 91, 209-217.
41. Cao H, Hu X, Zhang Q, Wang J, Li J, Liu B et al. (2014) Upregulation of let-7a inhibits vascular smooth muscle cell proliferation in vitro and in vein graft intimal hyperplasia in rats. J. Surg. Res. 192, 223-33.
42. Majid S, Dar AA, Saini S, Shahryari V, Arora S, Zaman MS et al. (2012) MicroRNA-1280 inhibits invasion and metastasis by targeting ROCK1 in bladder cancer. PLoS ONE 7, e46743.
43. Shi Z, Wei Q, Zhang M, She J (2014) MicroRNAs in bladder cancer: expression profiles, biological functions, regulation, and clinical implications. Crit. Rev. Eukaryot. Gene Expr. 24, 55-75.
44. Bae Y, Yang T, Zeng HC, Campeau PM, Chen Y, Bertin T et al. (2012) miRNA-34c regulates Notch signaling during bone development. Hum. Mol. Genet. 21, 2991-3000.
45. Xie W, Li Z, Li M, Xu N, Zhang Y (2013) miR-181a and inflammation: miRNA homeostasis response to inflammatory stimuli in vivo. Biochem. Biophys. Res. Commun. 430, 647-652.
46. Bandres E, Bitarte N, Arias F, Agorreta J, Fortes P, Agirre X et al. (2009) microRNA-451 regulates macrophage migration inhibitory factor production and proliferation of gastrointestinal cancer cells. Clin. Cancer Res. 15, 2281-2290.
47. Pichiorri F, Palmieri D, De Luca L, Consiglio J, You J, Rocci A et al. (2013) In vivo NCL targeting affects breast cancer aggressiveness through miRNA regulation. J. Exp. Med. 210, 951-968.
48. Duan Z, Choy E, Harmon D, Liu X, Susa M, Mankin H et al. (2011) MicroRNA-199a-3p is downregulated in human osteosarcoma and regulates cell proliferation and migration. Mol. Cancer Ther. 10, 1337-1345.
49. Furuta M, Kozaki KI, Tanaka S, Arii S, Imoto I, Inazawa J. (2010) miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma. Carcinogenesis 31, 766-776.
50. Kumar MS, Armenteros-Monterroso E, East P, Chakravorty P, Matthews N, Winslow MM et al. (2014) HMGA2 functions as a competing endogenous RNA to promote lung cancer progression. Nature 505, 212-217.
51. Wei A, Brisby H, Chung SA, Diwan AD (2008) Bone morphogenetic protein-7 protects human intervertebral disc cells in vitro from apoptosis. Spine J. 8, 466-474.
52. Jiang L, Zhang X, Zheng X, Ru A, Ni X, Wu Y et al. (2013) Apoptosis, senescence, and autophagy in rat nucleus pulposus cells: implications for diabetic intervertebral disc degeneration. J. Orthop. Res. 31, 692-702.
53. Ha KY, Kim BG, Kim KW, Oh IS, Seo JY (2011) Apoptosis in the sequestrated nucleus pulposus compared to the remaining nucleus pulposus in the same patient. Spine (Phila Pa 1976) 36: 683-689.
54. Murata Y, Nannmark U, Rydevik B, Takahashi K, Olmarker K (2008) The role of tumor necrosis factor-alpha in apoptosis of dorsal root ganglion cells induced by herniated nucleus pulposus in rats. Spine (Phila Pa 1976) 33: 155-162.
55. Wei Y, Nazari-Jahantigh M, Neth P, Weber C, Schober A (2013) MicroRNA-126, -145, and -155: a therapeutic triad in atherosclerosis? Arterioscler. Thromb. Vasc. Biol. 33, 449-454.
56. Wang Y, Li J, Tong L, Zhang J, Zhai A, Xu K et al. (2013) The prognostic value of miR-21 and miR-155 in non-small-cell lung cancer: a meta-analysis. Jpn. J. Clin. Oncol. 43, 813-820.
57. Li CL, Nie H, Wang M, Su LP, Li JF, Yu YY et al. (2012) microRNA-155 is downregulated in gastric cancer cells and involved in cell metastasis. Oncol. Rep. 27, 1960-1966.
58. Greither T, Grochola LF, Udelnow A, Lautenschlager C, Wurl P, Taubert H. (2010) Elevated expression of microRNAs 155, 203, 210 and 222 in pancreatic tumors is associated with poorer survival. Int. J. Cancer 126, 73-80.
59. Pu J, Bai D, Yang X, Lu X, Xu L, Lu J. (2012) Adrenaline promotes cell proliferation and increases chemoresistance in colon cancer HT29 cells through induction of miR-155. Biochem. Biophys. Res. Commun. 428, 210-215.
60. Wang HQ, Yu XD, Liu ZH, Cheng X, Samartzis D, Jia LT et al. (2011) Deregulated miR-155 promotes Fas-mediated apoptosis in human intervertebral disc degeneration by targeting FADD and caspase-3. J. Pathol. 225, 232-242.
61. Zhao X, Yang L, Hu J (2011) Down-regulation of miR-27a might inhibit proliferation and drug resistance of gastric cancer cells. J. Exp. Clin. Cancer Res. 30, 55.
62. Drayton RM, Dudziec E, Peter S, Bertz S, Hartmann A, Bryant HE et al. (2014) Reduced expression of miRNA-27a modulates cisplatin resistance in bladder cancer by targeting the cystine/glutamate exchanger SLC7A11. Clin. Cancer Res. 20, 1990-2000.
63. Hezova R, Kovarikova A, Bienertova-Vasku J, Sachlova M, Redova M, Vasku A et al. (2012) Evaluation of SNPs in miR-196-a2, miR-27a and miR-146a as risk factors of colorectal cancer. World J. Gastroenterol. 18, 2827-2831.
64. Liu T, Tang H, Lang Y, Liu M, Li X (2009) MicroRNA-27a functions as an oncogene in gastric adenocarcinoma by targeting prohibitin. Cancer Lett. 273, 233-242.
65. Liu G, Cao P, Chen H, Yuan W, Wang J, Tang X. (2013) MiR-27a regulates apoptosis in nucleus pulposus cells by targeting PI3K. PLoS ONE 8, e75251.
66. Wang W, Zhao LJ, Tan YX, Ren H, Qi ZT (2012) MiR-138 induces cell cycle arrest by targeting cyclin D3 in hepatocellular carcinoma. Carcinogenesis 33, 1113-1120.
67. Ma L (2010) Role of miR-10b in breast cancer metastasis. Breast Cancer Res. 12, 210.
68. Wang YY, Ye ZY, Zhao ZS, Li L, Wang YX, Tao HQ et al. (2013) Clinicopathologic significance of miR-10b expression in gastric carcinoma. Hum. Pathol. 44, 1278-85.
69. Li QJ, Zhou L, Yang F, Wang GX, Zheng H, Wang DS et al. (2012) MicroRNA-10b promotes migration and invasion through CADM1 in human hepatocellular carcinoma cells. Tumour Biol. 33, 1455-1465.
70. Frampton AE, Krell J, Zhang Y, Stebbing J, Castellano L, Jiao LR. (2012) The role of miR-10b in metastatic pancreatic ductal adenocarcinoma. Surgery 152, 936-8.
71. Ma L, Teruya-Feldstein J, Weinberg RA (2007) Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 449, 682-688.
72. Nakata K, Ohuchida K, Mizumoto K, Kayashima T, Ikenaga N, Sakai H. (2011) MicroRNA-10b is overexpressed in pancreatic cancer, promotes its invasiveness, and correlates with a poor prognosis. Surgery 150, 916-922.
73. Yu X, Li Z, Shen J, Wu WK, Liang J, Weng X et al. (2013) MicroRNA-10b promotes nucleus pulposus cell proliferation through RhoC-Akt pathway by targeting HOXD10 in intervetebral disc degeneration. PLoS ONE 8, e83080.
74. Cao Z, Yoon JH, Nam SW, Lee JY, Park WS (2012) PDCD4 expression inversely correlated with miR-21 levels in gastric cancers. J. Cancer Res. Clin. Oncol. 138, 611-619.
75. Iyevleva AG, Kuligina E, Mitiushkina NV, Togo AV, Miki Y, Imyanitov EN. (2012) High level of miR-21, miR-10b, and miR-31 expression in bilateral vs. unilateral breast carcinomas. Breast Cancer Res. Treat. 131, 1049-1059.
76. Haigl B, Vanas V, Setinek U, Hegedus B, Gsur A, Sutterlüty-Fall H. (2014) Expression of microRNA-21 in non-small cell lung cancer tissue increases with disease progression and is likely caused by growth conditional changes during malignant transformation. Int. J. Oncol. 44, 1325-1334.
77. Huang YH, Lin YH, Chi HC, Liao CH, Liao CJ, Wu SM et al. (2013) Thyroid hormone regulation of miR-21 enhances migration and invasion of hepatoma. Cancer Res. 73, 2505-2517.
78. Liu H, Huang X, Liu X, Xiao S, Zhang Y, Xiang T et al. (2014) miR-21 promotes human nucleus pulposus cell proliferation through PTEN/AKT signaling. Int. J. Mol. Sci. 15, 4007-4018.
79. Tian Y, Yuan W, Fujita N, Wang J, Wang H, Shapiro IM et al. (2013) Inflammatory cytokines associated with degenerative disc disease control aggrecanase-1 (ADAMTS-4) expression in nucleus pulposus cells through MAPK and NF-kappaB. Am. J. Pathol. 182, 2310-2321.
80. Roughley PJ (2004) Biology of intervertebral disc aging and degeneration: involvement of the extracellular matrix. Spine (Phila Pa 1976) 29: 2691-2699.
81. Huang M, Wang HQ, Zhang Q, Yan XD, Hao M, Luo ZJ. (2012) Alterations of ADAMTSs and TIMP-3 in human nucleus pulposus cells subjected to compressive load: implications in the pathogenesis of human intervertebral disc degeneration. J. Orthop. Res. 30, 267-273.
82. Hayes AJ, Benjamin M, Ralphs JR (2001) Extracellular matrix in development of the intervertebral disc. Matrix Biol. 20, 107-121.
83. Clouet J, Pot-Vaucel M, Grimandi G, Masson M, Lesoeur J, Fellah BH et al. (2011) Characterization of the age-dependent intervertebral disc changes in rabbit by correlation between MRI, histology and gene expression. BMC Musculoskelet. Disord. 12, 147.
84. Chen WH, Lo WC, Lee JJ, Su CH, Lin CT, Liu HY et al. (2006) Tissue-engineered intervertebral disc and chondrogenesis using human nucleus pulposus regulated through TGF-beta1 in platelet-rich plasma. J. Cell. Physiol. 209, 744-754.
85. Chen J, Liu Z, Zhong G, Qian L, Li Z, Qiao Z et al. (2014) Hypertrophy of ligamentum flavum in lumbar spine stenosis is associated with increased miR-155 level. Dis. Markers 2014, 786543.
86. Tsirimonaki E, Fedonidis C, Pneumaticos SG, Tragas AA, Michalopoulos I, Mangoura D. (2013) PKCepsilon signalling activates ERK1/2, and regulates aggrecan, ADAMTS5, and miR377 gene expression in human nucleus pulposus cells. PLoS ONE 8, e82045.