-
1
-
-
14944385553
-
Global cancer statistics
-
Parkin, D.M. et al. (2002) Global cancer statistics. CA Cancer J. Clin., 55, 74-108.
-
(2002)
CA Cancer J. Clin.
, vol.55
, pp. 74-108
-
-
Parkin, D.M.1
-
2
-
-
58149376548
-
Molecular mechanisms of hepatocellular carcinoma
-
Aravalli, R.N. et al. (2008) Molecular mechanisms of hepatocellular carcinoma. Hepatology, 48, 2047-2063.
-
(2008)
Hepatology
, vol.48
, pp. 2047-2063
-
-
Aravalli, R.N.1
-
3
-
-
57749086300
-
MicroRNAs and cancer: past, present, and potential future
-
Nelson, K.M. et al. (2008) MicroRNAs and cancer: past, present, and potential future. Mol. Cancer Ther., 7, 3655-3660.
-
(2008)
Mol. Cancer Ther.
, vol.7
, pp. 3655-3660
-
-
Nelson, K.M.1
-
4
-
-
0347444723
-
MicroRNAs: genomics, biogenesis, mechanism, and function
-
Bartel, D.P. et al. (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell, 116, 281-297.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
5
-
-
3042767202
-
MicroRNAs: small RNAs with a big role in gene regulation
-
He, L. et al. (2004) MicroRNAs: small RNAs with a big role in gene regulation. Nat. Rev. Genet., 5, 522-531.
-
(2004)
Nat. Rev. Genet.
, vol.5
, pp. 522-531
-
-
He, L.1
-
6
-
-
33750370444
-
MicroRNA signatures in human cancers
-
Calin, G.A. et al. (2006) MicroRNA signatures in human cancers. Nat. Rev. Cancer, 6, 857-866.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 857-866
-
-
Calin, G.A.1
-
7
-
-
33645294070
-
Oncomirs-microRNAs with a role in cancer
-
Esquela-Kerscher, A. et al. (2006) Oncomirs-microRNAs with a role in cancer. Nat. Rev. Cancer, 6, 259-269.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 259-269
-
-
Esquela-Kerscher, A.1
-
8
-
-
0034069495
-
Gene ontology: tool for the unification of biology. The Gene Ontology Consortium
-
Ashburner, M. et al. (2000) Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat. Genet., 25, 25-29.
-
(2000)
Nat. Genet.
, vol.25
, pp. 25-29
-
-
Ashburner, M.1
-
9
-
-
34250173488
-
Genome-scale analysis of in vivo spatiotemporal promoter activity in Caenorhabditis elegans
-
Dupuy, D. et al. (2007) Genome-scale analysis of in vivo spatiotemporal promoter activity in Caenorhabditis elegans. Nat. Biotechnol., 25, 663-668.
-
(2007)
Nat. Biotechnol.
, vol.25
, pp. 663-668
-
-
Dupuy, D.1
-
10
-
-
0346752107
-
From gene networks to gene function
-
Schlitt, T. et al. (2003) From gene networks to gene function. Genome Res., 13, 2568-2576.
-
(2003)
Genome Res
, vol.13
, pp. 2568-2576
-
-
Schlitt, T.1
-
11
-
-
0345863935
-
The KEGG resource for deciphering the genome
-
Kanehisa, M. et al. (2004) The KEGG resource for deciphering the genome. Nucleic Acids Res., 32, D277-D280.
-
(2004)
Nucleic Acids Res
, vol.32
-
-
Kanehisa, M.1
-
12
-
-
33644779844
-
WholePathwayScope: a comprehensive pathway-based analysis tool for high-throughput data
-
Yi, M. et al. (2006) WholePathwayScope: a comprehensive pathway-based analysis tool for high-throughput data. BMC Bioinformatics, 7, 30.
-
(2006)
BMC Bioinformatics
, vol.7
, pp. 30
-
-
Yi, M.1
-
13
-
-
34548400259
-
A systems biology approach for pathway level analysis
-
Draghici, S. et al. (2007) A systems biology approach for pathway level analysis. Genome Res., 17, 1537-1545.
-
(2007)
Genome Res
, vol.17
, pp. 1537-1545
-
-
Draghici, S.1
-
14
-
-
77956627711
-
The role of signaling pathways in the development and treatment of hepatocellular carcinoma
-
Whittaker, S. et al. (2010) The role of signaling pathways in the development and treatment of hepatocellular carcinoma. Oncogene, 29, 4989-5005.
-
(2010)
Oncogene
, vol.29
, pp. 4989-5005
-
-
Whittaker, S.1
-
15
-
-
79952036568
-
Mitogen-activated protein kinases in hepatocellular carcinoma development
-
Min, L. et al. (2011) Mitogen-activated protein kinases in hepatocellular carcinoma development. Semin. Cancer Biol., 21, 10-20.
-
(2011)
Semin. Cancer Biol.
, vol.21
, pp. 10-20
-
-
Min, L.1
-
16
-
-
58949088366
-
Liver stem cells and hepatocellular carcinoma
-
Mishra, L. et al. (2009) Liver stem cells and hepatocellular carcinoma. Hepatology, 49, 318-329.
-
(2009)
Hepatology
, vol.49
, pp. 318-329
-
-
Mishra, L.1
-
17
-
-
59049093707
-
Wnt signaling in liver cancer
-
Takigawa, Y. et al. (2008) Wnt signaling in liver cancer. Curr. Drug Targets, 9, 1013-1024.
-
(2008)
Curr. Drug Targets
, vol.9
, pp. 1013-1024
-
-
Takigawa, Y.1
-
18
-
-
46249095814
-
MicroRNA expression profiling: a molecular tool for defining the phenotype of hepatocellular tumors
-
Braconi, C. et al. (2008) MicroRNA expression profiling: a molecular tool for defining the phenotype of hepatocellular tumors. Hepatology, 47, 1807-1809.
-
(2008)
Hepatology
, vol.47
, pp. 1807-1809
-
-
Braconi, C.1
-
19
-
-
46249083024
-
MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations
-
Ladeiro, Y. et al. (2008) MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations. Hepatology, 47, 1955-1963.
-
(2008)
Hepatology
, vol.47
, pp. 1955-1963
-
-
Ladeiro, Y.1
-
20
-
-
68949190853
-
MicroRNAs involved in tumor suppressor and oncogene pathways: implications for hepatobiliary neoplasia
-
Mott, J.L. (2009) MicroRNAs involved in tumor suppressor and oncogene pathways: implications for hepatobiliary neoplasia. Hepatology, 50, 630-637.
-
(2009)
Hepatology
, vol.50
, pp. 630-637
-
-
Mott, J.L.1
-
21
-
-
77955970127
-
Role of microRNA-199a-5p and discoidin domain receptor 1 in human hepatocellular carcinoma invasion
-
Shen, Q.L. et al. (2010) Role of microRNA-199a-5p and discoidin domain receptor 1 in human hepatocellular carcinoma invasion. Mol. Cancer, 9, 227-239.
-
(2010)
Mol. Cancer
, vol.9
, pp. 227-239
-
-
Shen, Q.L.1
-
22
-
-
79952228130
-
MicroRNAs miR-199a-5p and -3p target the Brm subunit of SWI/SNF to generate a double-negative feed back loop in a variety of human cancers
-
Sakurai, K. et al. (2011) MicroRNAs miR-199a-5p and -3p target the Brm subunit of SWI/SNF to generate a double-negative feed back loop in a variety of human cancers. Cancer Res., 75, 1680-1689.
-
(2011)
Cancer Res
, vol.75
, pp. 1680-1689
-
-
Sakurai, K.1
-
23
-
-
79955836205
-
Micro-RNA expression in cisplatin resistant germ cell tumor cell lines
-
Port, M. (2011) Micro-RNA expression in cisplatin resistant germ cell tumor cell lines. Mol. Cancer, 10, 52-59.
-
(2011)
Mol. Cancer
, vol.10
, pp. 52-59
-
-
Port, M.1
-
24
-
-
78449302631
-
Deregulation of miR-519a, 153, and 485-5p and its clinicopathological relevance in ovarian epithelial tumours
-
Kim, T.H. et al. (2010) Deregulation of miR-519a, 153, and 485-5p and its clinicopathological relevance in ovarian epithelial tumours. Histopathology, 57, 734-743.
-
(2010)
Histopathology
, vol.57
, pp. 734-743
-
-
Kim, T.H.1
-
25
-
-
70749095079
-
Frequent amplification of a chr19q13.41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors
-
Li, M. et al. (2009) Frequent amplification of a chr19q13.41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors. Cancer Cell, 16, 533-546.
-
(2009)
Cancer Cell
, vol.16
, pp. 533-546
-
-
Li, M.1
-
26
-
-
68149178467
-
Down-regulated miR-9 and miR-433 in human gastric carcinoma
-
Luo, H. et al. (2009) Down-regulated miR-9 and miR-433 in human gastric carcinoma. J. Exp. Clin. Cancer Res., 28, 82-90.
-
(2009)
J. Exp. Clin. Cancer Res.
, vol.28
, pp. 82-90
-
-
Luo, H.1
-
27
-
-
79958270237
-
miRNA expression in colon polyps provides evidence for a multihit model of colon cancer
-
Oberg, A.L. (2011) miRNA expression in colon polyps provides evidence for a multihit model of colon cancer. PLoS One, 6, e20465.
-
(2011)
PLoS One
, vol.6
-
-
Oberg, A.L.1
-
28
-
-
40249092910
-
MicroRNA-21 targets tumor suppressor genes in invasion and metastasis
-
Zhu, S. et al. (2008) MicroRNA-21 targets tumor suppressor genes in invasion and metastasis. Cell Res., 18, 350-359.
-
(2008)
Cell Res
, vol.18
, pp. 350-359
-
-
Zhu, S.1
-
29
-
-
66149114383
-
MicroRNA-122, a tumor suppressor microRNA that regulates intrahepatic metastasis of hepatocellular carcinoma
-
Tsai, W.C. et al. (2009) MicroRNA-122, a tumor suppressor microRNA that regulates intrahepatic metastasis of hepatocellular carcinoma. Hepatology, 49, 1571-1582.
-
(2009)
Hepatology
, vol.49
, pp. 1571-1582
-
-
Tsai, W.C.1
-
30
-
-
70450285075
-
MicroRNA-122 inhibits tumorigenic properties of hepatocellular carcinoma cells and sensitizes these cells to sorafenib
-
Bai, S. et al. (2009) MicroRNA-122 inhibits tumorigenic properties of hepatocellular carcinoma cells and sensitizes these cells to sorafenib. J. Biol. Chem., 284, 32015-32027.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 32015-32027
-
-
Bai, S.1
-
31
-
-
79955842428
-
P-glycoprotein enhances radiation-induced apoptotic cell death through the regulation of miR-16 and Bcl-2 expressions in hepatocellular carcinoma cells
-
Tsang, T.Y. et al. (2011) P-glycoprotein enhances radiation-induced apoptotic cell death through the regulation of miR-16 and Bcl-2 expressions in hepatocellular carcinoma cells. Apoptosis, 16, 524-535.
-
(2011)
Apoptosis
, vol.16
, pp. 524-535
-
-
Tsang, T.Y.1
-
32
-
-
79961126724
-
miR-29c targets TNFAIP3, inhibits cell proliferation and induces apoptosis in hepatitis B virus-related hepatocellular carcinoma
-
Wang, C.M. et al. (2011) miR-29c targets TNFAIP3, inhibits cell proliferation and induces apoptosis in hepatitis B virus-related hepatocellular carcinoma. Biochem. Biophys. Res. Commun., 411, 586-592.
-
(2011)
Biochem. Biophys. Res. Commun.
, vol.411
, pp. 586-592
-
-
Wang, C.M.1
-
33
-
-
80055047968
-
MicroRNA-29b suppresses tumor angiogenesis, invasion, and metastasis by regulating matrix metalloproteinase 2 expression
-
Fang, J.H. et al. (2011) MicroRNA-29b suppresses tumor angiogenesis, invasion, and metastasis by regulating matrix metalloproteinase 2 expression. Hepatology, 54, 1729-1740.
-
(2011)
Hepatology
, vol.54
, pp. 1729-1740
-
-
Fang, J.H.1
-
34
-
-
79956079665
-
Does the hepatitis B antigen HBx promote the appearance of liver cancer stem cells?
-
Arzumanyan, A. et al. (2011) Does the hepatitis B antigen HBx promote the appearance of liver cancer stem cells? Cancer Res., 71, 3701-3708.
-
(2011)
Cancer Res
, vol.71
, pp. 3701-3708
-
-
Arzumanyan, A.1
-
35
-
-
80053184413
-
Deregulated expression of microRNA-221 with the potential for prognostic biomarkers in surgically resected hepatocellular carcinoma
-
Yoon, S.O. et al. (2011) Deregulated expression of microRNA-221 with the potential for prognostic biomarkers in surgically resected hepatocellular carcinoma. Hum. Pathol., 42, 1391-1400.
-
(2011)
Hum. Pathol.
, vol.42
, pp. 1391-1400
-
-
Yoon, S.O.1
-
36
-
-
69349083676
-
MicroRNA-221 targets Bmf in hepatocellular carcinoma and Correlates with tumor multifocality
-
Gramantieri, L. et al. (2009) MicroRNA-221 targets Bmf in hepatocellular carcinoma and Correlates with tumor multifocality. Clin. Cancer Res., 15, 5073-5081.
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 5073-5081
-
-
Gramantieri, L.1
-
37
-
-
50549084147
-
Diagnostic and prognostic implications of microRNAs in human hepatocellular carcinoma
-
Li, W. et al. (2008) Diagnostic and prognostic implications of microRNAs in human hepatocellular carcinoma. Int. J. Cancer, 123, 1616-1622.
-
(2008)
Int. J. Cancer
, vol.123
, pp. 1616-1622
-
-
Li, W.1
-
38
-
-
77951796658
-
PKC alpha mediated induction of miR-101 in human hepatoma HepG2 cells
-
Chiang, C.W. et al. (2010) PKC alpha mediated induction of miR-101 in human hepatoma HepG2 cells. J. Biomed. Sci., 17, 35.
-
(2010)
J. Biomed. Sci.
, vol.17
, pp. 35
-
-
Chiang, C.W.1
-
39
-
-
77954442675
-
Downregulation of the Rho GTPase signaling pathway is involved in the microRNA-138-mediated inhibition of cell migration and invasion in tongue squamous cell carcinoma
-
Jiang, L. et al. (2010) Downregulation of the Rho GTPase signaling pathway is involved in the microRNA-138-mediated inhibition of cell migration and invasion in tongue squamous cell carcinoma. Int. J. Cancer, 127, 505-512.
-
(2010)
Int. J. Cancer
, vol.127
, pp. 505-512
-
-
Jiang, L.1
-
40
-
-
84863229770
-
MiR-138 suppresses expression of hypoxia-inducible factor 1 (HIF-1) in clear cell renal cell carcinoma 786-O cells
-
Song, T. et al. (2011) MiR-138 suppresses expression of hypoxia-inducible factor 1 (HIF-1) in clear cell renal cell carcinoma 786-O cells. Asian Pac. J. Cancer Prev., 12, 1307-1311.
-
(2011)
Asian Pac. J. Cancer Prev.
, vol.12
, pp. 1307-1311
-
-
Song, T.1
-
41
-
-
80054884390
-
MicroRNA-138 suppresses epithelial-mesenchymal transition in squamous cell carcinoma cell lines
-
Liu, X. et al. (2011) MicroRNA-138 suppresses epithelial-mesenchymal transition in squamous cell carcinoma cell lines. Biochem. J., 440, 23-31.
-
(2011)
Biochem. J.
, vol.440
, pp. 23-31
-
-
Liu, X.1
-
42
-
-
81155132245
-
Molecular characterization of the microRNA-138-Foslike antigen 1 (FOSL1) regulatory module in squamous cell carcinoma
-
Jin, Y. et al. (2011) Molecular characterization of the microRNA-138-Foslike antigen 1 (FOSL1) regulatory module in squamous cell carcinoma. J. Biol. Chem., 286, 40104-40109.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 40104-40109
-
-
Jin, Y.1
-
43
-
-
78951488760
-
Identification and experimental validation of G protein alpha inhibiting activity polypeptide 2 (GNAI2) as a microRNA-138 target in tongue squamous cell carcinoma
-
Jiang, L. et al. (2011) Identification and experimental validation of G protein alpha inhibiting activity polypeptide 2 (GNAI2) as a microRNA-138 target in tongue squamous cell carcinoma. Hum. Genet., 129, 189-197.
-
(2011)
Hum. Genet.
, vol.129
, pp. 189-197
-
-
Jiang, L.1
-
44
-
-
0035848706
-
Cdk6-cyclin D3 complex evades inhibition by inhibitor proteins and uniquely controls cell's proliferation competence
-
Lin, J. et al. (2001) Cdk6-cyclin D3 complex evades inhibition by inhibitor proteins and uniquely controls cell's proliferation competence. Oncogene, 20, 2000-2009.
-
(2001)
Oncogene
, vol.20
, pp. 2000-2009
-
-
Lin, J.1
-
45
-
-
52649088391
-
The miR-16 family induces cell cycle arrest by regulating multiple cell cycle genes
-
Liu, Q. et al. (2008) The miR-16 family induces cell cycle arrest by regulating multiple cell cycle genes. Nucleic Acids Res., 36, 5391-5404.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 5391-5404
-
-
Liu, Q.1
-
46
-
-
33645278944
-
Validation of cyclin D1/CDK4 as an anticancer drug target in MCF-7 breast cancer cells: effect of regulated overexpression of cyclin D1 and siRNA-mediated inhibition of endogenous cyclin D1 and CDK4 expression
-
Grillo, M. et al. (2006) Validation of cyclin D1/CDK4 as an anticancer drug target in MCF-7 breast cancer cells: effect of regulated overexpression of cyclin D1 and siRNA-mediated inhibition of endogenous cyclin D1 and CDK4 expression. Breast Cancer Res. Treat., 95, 185-194.
-
(2006)
Breast Cancer Res. Treat.
, vol.95
, pp. 185-194
-
-
Grillo, M.1
-
47
-
-
33645226613
-
Cyclin D3 maintains growth-inhibitory activity of C/EBPalpha by stabilizing C/EBPalpha-cdk2 and C/EBPalpha-Brm complexes
-
Wang, G.L. et al. (2006) Cyclin D3 maintains growth-inhibitory activity of C/EBPalpha by stabilizing C/EBPalpha-cdk2 and C/EBPalpha-Brm complexes. Mol. Cell. Biol., 26, 2570-2582.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 2570-2582
-
-
Wang, G.L.1
-
48
-
-
52649088391
-
miR-16 family induces cell cycle arrest by regulating multiple cell cycle genes
-
Liu, Q. et al. (2008) miR-16 family induces cell cycle arrest by regulating multiple cell cycle genes. Nucleic Acids Res., 36, 5391-5404.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 5391-5404
-
-
Liu, Q.1
-
49
-
-
0035848706
-
Cdk6-cyclin D3 complex evades inhibition by inhibitor proteins and uniquely controls cell's proliferation competence
-
Lin, J. et al. (2001) Cdk6-cyclin D3 complex evades inhibition by inhibitor proteins and uniquely controls cell's proliferation competence. Oncogene, 20, 2000-2009.
-
(2001)
Oncogene
, vol.20
, pp. 2000-2009
-
-
Lin, J.1
-
50
-
-
0842265003
-
Cdk6-cyclin D3 activity in murine ES cells is resistant to inhibition by p16INK4a
-
Renate, F. et al. (2004) Cdk6-cyclin D3 activity in murine ES cells is resistant to inhibition by p16INK4a. Oncogene, 23, 491-502.
-
(2004)
Oncogene
, vol.23
, pp. 491-502
-
-
Renate, F.1
-
51
-
-
78651411120
-
MiR-26a inhibits cell growth and tumorigenesis of nasopharyngeal carcinoma through repression of EZH2
-
Lu, J. et al. (2011) MiR-26a inhibits cell growth and tumorigenesis of nasopharyngeal carcinoma through repression of EZH2. Cancer Res., 71, 225-233.
-
(2011)
Cancer Res
, vol.71
, pp. 225-233
-
-
Lu, J.1
-
52
-
-
78650530938
-
Enhanced expression of cyclins and cyclin-dependent kinases in aniline-induced cell proliferation in rat spleen
-
Wang, J. et al. (2011) Enhanced expression of cyclins and cyclin-dependent kinases in aniline-induced cell proliferation in rat spleen. Toxicol. Appl. Pharmacol., 250, 213-220.
-
(2011)
Toxicol. Appl. Pharmacol.
, vol.250
, pp. 213-220
-
-
Wang, J.1
|