Characterization of immunoglobulin adsorption on dextran-grafted hydrophobic charge-induction resins: Cross-effects of ligand density and pH/salt concentration

Journal of Chromatography A

Volumn 1396, Issue , 2015, Pages 45-53

  Liu, Tao ^a   Lin, Dong Qiang ^b   Zhang, Qi Lei ^a   Yao, Shan Jing ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

Author keywords

Dextran grafted resin; Hydrophobic charge induction chromatography; Ligand density; PH; Protein adsorption; Salt concentration

Indexed keywords

DEXTRAN; GRAFTING (CHEMICAL); HYDROPHOBIC CHROMATOGRAPHY; HYDROPHOBICITY; LIGANDS; PH; PH EFFECTS; PROTEINS; RESINS; SODIUM CHLORIDE;

GRAFTED RESIN; HYDROPHOBIC CHARGE INDUCTION CHROMATOGRAPHIES; LIGAND DENSITY; PROTEIN ADSORPTION; SALT CONCENTRATION;

ADSORPTION;

2 MERCAPTO 1 METHYL IMIDAZOLE; DEXTRAN; IMIDAZOLE DERIVATIVE; IMMUNOGLOBULIN G; SODIUM CHLORIDE; UNCLASSIFIED DRUG; 2-MERCAPTO-1-METHYLIMIDAZOLE; DEXTRANS; IMIDAZOLES; LIGANDS; SEPHAROSE;

ADSORPTION KINETICS; ARTICLE; BINDING AFFINITY; CHEMICAL MODIFICATION; CHROMATOGRAPHY; CONCENTRATION RESPONSE; CONTROLLED STUDY; EFFECTIVE PORE DIFFUSIVITY; HYDROPHOBIC CHARGE INDUCTION CHROMATOGRAPHY; LIGAND BINDING; LIGAND DENSITY; LIQUID; PH; PHYSICAL PARAMETERS; PRIORITY JOURNAL; SALT TOLERANCE; SATURATED ADSORPTION CAPACITY; SOLID; STATIC ADSORPTION EQUILIBRIUM; TRANSPORT KINETICS; ADSORPTION; CHEMISTRY; CHROMATOGRAPHY, LIQUID; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS;

ADSORPTION; CHROMATOGRAPHY, LIQUID; DEXTRANS; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; IMIDAZOLES; IMMUNOGLOBULIN G; LIGANDS; SEPHAROSE; SODIUM CHLORIDE;

EID: 84928760656     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2015.03.074     Document Type: Article

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