Characterization of novel mixed-mode protein adsorbents fabricated from benzoyl-modified polyethyleneimine-grafted Sepharose

Journal of Chromatography A

Volumn 1372, Issue , 2014, Pages 157-165

  Liu, Na ^a   Wang, Ziyuan ^a   Liu, Xiaoguang Margaret ^b,c   Yu, Linling ^a,b   Sun, Yan ^a,b  

^a TIANJIN UNIVERSITY   (China)

^b SynBio Research Platform   (China)

^c University of Alabama   (United States)

Author keywords

Benzoyl density; Ionic strength; Mixed mode chromatography; Poly(ethylenimine) chain; Protein adsorption; Uptake kinetics

Indexed keywords

ADSORPTION; BENZOIC ACID; BINDING ENERGY; BIOCHEMISTRY; CHROMATOGRAPHIC ANALYSIS; FABRICATION; GRAFTING (CHEMICAL); INTEGRATED CIRCUITS; ION CHROMATOGRAPHY; ION EXCHANGE; IONIC STRENGTH; MAMMALS; POLYELECTROLYTES; PROTEINS; RESINS;

ADSORPTION EQUILIBRIA; ANTIBODY PURIFICATION; CATIONIC POLYELECTROLYTE; ION EXCHANGE CHROMATOGRAPHY; MIXED-MODE CHROMATOGRAPHY; POLY(ETHYLENIMINE); PROTEIN ADSORPTION; UPTAKE KINETICS;

CALCIUM COMPOUNDS;

ADSORBENT; BENZOIC ACID; BOVINE SERUM ALBUMIN; IMMUNOGLOBULIN; POLYETHYLENEIMINE; RESIN; SEPHAROSE;

ADSORPTION KINETICS; ARTICLE; BINDING AFFINITY; CHEMICAL ANALYSIS; CONCENTRATION (PARAMETERS); ELUTION; HYDROPHOBICITY; ION EXCHANGE CHROMATOGRAPHY; IONIC STRENGTH; MATHEMATICAL ANALYSIS; PH; PHYSICAL PARAMETERS;

EID: 84916226811     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2014.10.108     Document Type: Article

References (46)

1. Shi Q.-H., Jia G.-D., Sun Y. Dextran-grafted cation exchanger based on superporous agarose gel: adsorption isotherms, uptake kinetics and dynamic protein adsorption performance. J. Chromatogr. A 2010, 1217:5084-5091.
2. Lenhoff A.M. Protein adsorption and transport in polymer-functionalized ion-exchangers. J. Chromatogr. A 2011, 1218:8748-8759.
3. Tao Y., Carta G. Rapid monoclonal antibody adsorption on dextran-grafted agarose media for ion-exchange chromatography. J. Chromatogr. A 2008, 1211:70-79.
4. Stone M.C., Carta G. Protein adsorption and transport in agarose and dextran-grafted agarose media for ion exchange chromatography. J. Chromatogr. A 2007, 1146:202-215.
5. Stone M.C., Tao Y., Carta G. Protein adsorption and transport in agarose and dextran-grafted agarose media for ion exchange chromatography: effect of ionic strength and protein characteristics. J. Chromatogr. A 2009, 1216:4465-4474.
6. Yu L.-L., Tao S.-P., Dong X.-Y., Sun Y. Protein adsorption to poly(ethylenimine)-modified Sepharose FF: I. A critical ionic capacity for drastically enhanced capacity and uptake kinetics. J. Chromatogr. A 2013, 1305:76-84.
7. Yu L.-L., Sun Y. Protein adsorption to poly(ethylenimine)-modified Sepharose FF: II. Effect of ionic strength. J. Chromatogr. A 2013, 1305:85-93.
8. Hong Y., Liu N., Wei W., Yu L.-L., Ma G., Sun Y. Protein adsorption to poly(ethylenimine)-modified Sepharose FF: III. Comparison between different proteins. J. Chromatogr. A 2014, 1342:30-36.
9. Bowes B.D., Koku H., Czymmek K.J., Lenhoff A.M. Protein adsorption and transport in dextran-modified ion-exchange media: I. Adsorption. J. Chromatogr. A 2009, 1216:7774-7784.
10. Liu N., Yu L.-L., Sun Y. Protein adsorption to poly(ethylenimine)-modified Sepharose FF: IV. Dynamic adsorption and elution behaviors. J. Chromatogr. A 2014, 1362:218-224.
11. Tao Y., Carta G., Ferreira G., Robbins D. Adsorption of deamidated antibody variants on macroporous and dextran-grafted cation exchangers: I. Adsorption equilibrium. J. Chromatogr. A 2011, 1218:1519-1529.
12. Zhao G., Dong X.-Y., Sun Y. Ligands for mixed-mode protein chromatography: principles, characteristics and design. J. Biotechnol. 2009, 144:3-11.
13. Yang Y., Geng X. Mixed-mode chromatography and its applications to biopolymers. J. Chromatogr. A 2011, 1218:8813-8825.
14. Burton S.C., Harding D.R.K. Salt-independent adsorption chromatography: new broad-spectrum affinity methods for protein capture. J. Biochem. Biophys. Methods 2001, 49:275-287.
15. Burton S.C., Haggarty N.W., Harding D.R.K. One step purification of chymosin by mixed mode chromatography. Biotechnol. Bioeng. 1997, 56:45-55.
16. Burton S.C., Harding D.R.K. Hydrophobic charge induction chromatography: salt independent protein adsorption and facile elution with aqueous buffers. J. Chromatogr. A 1998, 814:71-81.
17. Davies N.H., Euerby M.R., McCalley D.V. A study of retention and overloading of basic compounds with mixed-mode reversed-phase/cation-exchange columns in high performance liquid chromatography. J. Chromatogr. A 2007, 1138:65-72.
18. Kasche V., Löffler F., Scholzen T., Krämer D.M., Boller T. Rapid protein purification using phenylbutylamine - Eupergit: a novel method for large-scale procedures. J. Chromatogr. 1990, 510:149-154.
19. Zhao G., Peng G., Li F., Shi Q., Sun Y. 5-Aminoindole, a new ligand for hydrophobic charge induction chromatography. J. Chromatogr. A 2008, 1211:90-98.
20. Schwartz W., Judd D., Wysocki M., Guerrier L., Birck-Wilson E., Boschetti E. Comparison of hydrophobic charge induction chromatography with affinity chromatography on protein A for harvest and purification of antibodies. J. Chromatogr. A 2001, 908:251-263.
21. Boschetti E. Antibody separation by hydrophobic charge induction chromatography. Trends Biotechnol. 2002, 20:333-337.
22. Hevehan D.L., De Bernardez Clark E. Oxidative renaturation of lysozyme at high concentrations. Biotechnol. Bioeng. 1997, 54:221-230.
23. Hahn R., Deinhofer K., Machold C., Jungbauer A. Hydrophobic interaction chromatography of proteins: II. Binding capacity, recovery and mass transfer properties. J. Chromatogr. B 2003, 790:99-114.
24. Yu L.-L., Dong X.-Y., Sun Y. Ion-exchange resins facilitate like-charged protein refolding: effects of porous solid phase properties. J. Chromatogr. A 2012, 1225:168-173.
25. Lee Y.J., Notides A.C., Tsay Y.-G., Kende A.S. Coumestrol, NBD-norhexestrol, and dansyl-norhexestrol, fluorescent probes of estrogen-binding proteins. Biochemistry 1977, 16:2896-2901.
26. Kilár F., Simon I., Lakatos S., Vonderviszt F., Medgyesi G.A., Zá Vodszky P. Conformation of human IgG subclasses in solution. Eur. J. Biochem. 1985, 147:17-25.
27. Davies R.C., Neuberger A., Wilson B.M. The dependence of lysozyme activity on pH and ionic strength. Biochim. Biophys. Acta - Enzymol. 1969, 178:294-305.
28. Janolino V.G., Swaisgood H.E. Analysis and optimization of methods using water-soluble carbodiimide for immobilization of biochemicals to porous glass. Biotechnol. Bioeng. 1982, 24:1069-1080.
29. Yu L.-L., Shi Q.-H., Sun Y. Effect of dextran layer on protein uptake to dextran-grafted adsorbents for ion-exchange and mixed-mode chromatography. J. Sep. Sci. 2011, 34:2950-2959.
30. Heinänen M., Barbas C. Validation of an HPLC method for the quantification of ambroxol hydrochloride and benzoic acid in a syrup as pharmaceutical form stress test for stability evaluation. J. Pharm. Biomed. Anal. 2001, 24:1005-1010.
31. Mu G., Liu H., Gao Y., Luan F. Determination of benzoyl peroxide, as benzoic acid, in wheat flour by capillary electrophoresis compared with HPLC. J. Sci. Food Agric. 2012, 92:960-964.
32. He L., Niemeyer B. A novel correlation for protein diffusion coefficients based on molecular weight and radius of gyration. Biotechnol. Prog. 2003, 19:544-548.
33. Gao D., Lin D.-Q., Yao S.-J. Mechanistic analysis on the effects of salt concentration and pH on protein adsorption onto a mixed-mode adsorbent with cation ligand. J. Chromatogr. B 2007, 859:16-23.
34. Thomas H., Coquebert de Neuville B., Storti G., Morbidelli M., Joehnck M., Schulte M. Role of tentacles and protein loading on pore accessibility and mass transfer in cation exchange materials for proteins. J. Chromatogr. A 2013, 1285:48-56.
35. Amara M., Kerdjoudj H. Modification of the cation exchange resin properties by impregnation in polyethyleneimine solutions: application to the separation of metallic ions. Talanta 2003, 60:991-1001.
36. Nagaya J., Homma M., Tanioka A., Minakata A. Relationship between protonation and ion condensation for branched poly(ethylenimine). Biophys. Chem. 1996, 60:45-51.
37. Hostetler R.E., Swanson J.W. Diffusion into and adsorption of polyethylenimine on porous silica gel. J. Poly. Sci: Poly. Chem. Ed. 1974, 12:29-43.
38. Wang R.-Z., Lin D.-Q., Tong H.-F., Lu H.-L., Yao S.-J. Evaluation of mixed-mode chromatographic resins for separating IgG from serum albumin containing feedstock. J. Chromatogr. B 2013, 936:33-41.
39. Zhou X.-P., Li W., Shi Q.-H., Sun Y. Analysis of mass transport models for protein adsorption to cation exchanger by visualization with confocal laser scanning microscopy. J. Chromatogr. A 2006, 1103:110-117.
40. Wesselingh J.A., Bosma J.C. Protein ion-exchange adsorption kinetics. AIChE J. 2001, 47:1571-1580.
41. Chang Y.-K., Chou S.-Y., Liu J.-L., Tasi J.-C. Characterization of BSA adsorption on mixed mode adsorbent: I. Equilibrium study in a well-agitated contactor. Biochem. Eng. J. 2007, 35:56-65.
42. Shi Q.-H., Cheng Z., Sun Y. 4-(1H-imidazol-1-yl) aniline: a new ligand of mixed-mode chromatography for antibody purification. J. Chromatogr. A 2009, 1216:6081-6087.
43. Gao D., Lin D.-Q., Yao S.-J. Protein adsorption kinetics of mixed-mode adsorbent with benzylamine as functional ligand. Chem. Eng. Sci. 2006, 61:7260-7268.
44. Martenson R.E. The use of gel filtration to follow conformational changes in proteins. Conformational flexibility of bovine myelin basic protein. J. Biol. Chem. 1978, 253:8887-8893.
45. Lu H.-L., Lin D.-Q., Gao D., Yao S.-J. Evaluation of immunoglobulin adsorption on the hydrophobic charge-induction resins with different ligand densities and pore sizes. J. Chromatogr. A 2013, 1278:61-68.
46. Xie B., Li X., Dong X.-Y., Sun Y. Insight into the inhibition effect of acidulated serum albumin on amyloid β-protein fibrillogenesis and cytotoxicity. Langmuir 2014, 30:9789-9796.