Influence of ligand density on antibody binding capacity of cation-exchange adsorbents

Journal of Chromatography A

Volumn 1216, Issue 25, 2009, Pages 5039-5044

  Wrzosek, Katarzyna ^a   Gramblička, Michal ^a   Polakovič, Milan ^a  

^a SLOVAK UNIVERSITY OF TECHNOLOGY   (Slovakia)

Author keywords

Adsorption capacity; Cation exchange chromatography; Ionic strength; Ligand density; Monoclonal antibody; pH influence

Indexed keywords

ADSORPTION CAPACITIES; ADSORPTION CAPACITY; ADSORPTION PROPERTIES; ANOMALOUS EFFECTS; ANTIBODY BINDING; CATION EXCHANGERS; CATION EXCHANGES; CATION-EXCHANGE CHROMATOGRAPHY; HUMAN IMMUNOGLOBULIN; LIGAND DENSITY; LIGAND GROUPS; NACL CONCENTRATION; POLYCLONAL; POLYMETHACRYLATE; STATIC ADSORPTION; STRENGTH VALUES;

ADSORPTION; ALLERGIES; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; ION EXCHANGE; IONIC STRENGTH; LIGANDS; MERGERS AND ACQUISITIONS; MONOCLONAL ANTIBODIES; POSITIVE IONS; SODIUM CHLORIDE; SURFACE PLASMON RESONANCE;

PH EFFECTS;

ADSORBENT; IMMUNOGLOBULIN G; LIGAND; MONOCLONAL ANTIBODY; POLYCLONAL ANTIBODY; POLYMETHACRYLIC ACID; SODIUM CHLORIDE;

ADSORPTION; ANTIGEN BINDING; ARTICLE; CATION EXCHANGE; DENSITY; ION EXCHANGE CHROMATOGRAPHY; IONIC STRENGTH; PH; PRIORITY JOURNAL; PROTEIN PURIFICATION;

ADSORPTION; ANTIBODIES, MONOCLONAL; CATION EXCHANGE RESINS; CHROMATOGRAPHY, ION EXCHANGE; HUMANS; HYDROGEN-ION CONCENTRATION; IMMUNOGLOBULIN G; LIGANDS; OSMOLAR CONCENTRATION; PROTEIN BINDING; SODIUM CHLORIDE;

EID: 65649117403     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2009.04.073     Document Type: Article

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