Mitochondrial Ca2+-dependent NLRP3 activation exacerbates the Pseudomonas aeruginosa-driven inflammatory response in cystic fibrosis

Nature Communications

Volumn 6, Issue , 2015, Pages

  Rimessi, Alessandro ^a   Bezzerri, Valentino ^b   Patergnani, Simone ^a   Marchi, Saverio ^a   Cabrini, Giulio ^b   Pinton, Paolo ^a  

^a UNIVERSITY OF FERRARA   (Italy)

^b UNIVERSITY HOSPITAL OF VERONA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CALCIUM ION; CRYOPYRIN; FLAGELLIN; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; MITOCHONDRIAL CALCIUM UNIPORTER; SIGNAL PEPTIDE; UNCLASSIFIED DRUG; CALCIUM; CALCIUM CHANNEL; CARRIER PROTEIN; CFTR PROTEIN, HUMAN; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; NLRP3 PROTEIN, HUMAN;

BACTERIUM; CALCIUM; CELLS AND CELL COMPONENTS; CYTOGENETICS; MITOCHONDRION; PATHOLOGY; PROTEIN; RESPIRATORY DISEASE;

ARTICLE; BACTERIAL STRAIN; CALCIUM HOMEOSTASIS; CELL ORGANELLE; CONTROLLED STUDY; CYSTIC FIBROSIS; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLAMMATION; MITOCHONDRION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING; PSEUDOMONAS AERUGINOSA; AGONISTS; BIOSYNTHESIS; BRONCHUS; CALCIUM SIGNALING; CELL CULTURE; EPITHELIUM CELL; GENE EXPRESSION REGULATION; GENETICS; HOST PATHOGEN INTERACTION; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PATHOLOGY; PHYSIOLOGY; SECRETION (PROCESS);

PSEUDOMONAS AERUGINOSA;

BRONCHI; CALCIUM; CALCIUM CHANNELS; CALCIUM SIGNALING; CARRIER PROTEINS; CELLS, CULTURED; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; EPITHELIAL CELLS; FLAGELLIN; GENE EXPRESSION REGULATION; HOST-PATHOGEN INTERACTIONS; HUMANS; INFLAMMATION; INTERLEUKIN-18; INTERLEUKIN-1BETA; MITOCHONDRIA; PSEUDOMONAS AERUGINOSA;

EID: 84928706286     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms7201     Document Type: Article

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