Role of flagella in pathogenesis of Pseudomonas aeruginosa pulmonary infection

Infection and Immunity

Volumn 66, Issue 1, 1998, Pages 43-51

  Feldman, Matthew ^a   Bryan, Ruth ^a   Rajan, Sujatha ^a   Scheffler, Lee ^a   Brunnert, Steven ^a   Tang, Hope ^a   Prince, Alice ^a  

^a New York Presbyterian Columbia University Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLAGELLIN; GANGLIOSIDE GD 1A; GANGLIOSIDE GM1; GANGLIOTETRAOSYLCERAMIDE; MUCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL PNEUMONIA; BACTERIAL VIRULENCE; BACTERIUM MUTANT; BACTERIUM PILUS; CELL MOTILITY; CHEMOTAXIS; CHO CELL; CONTROLLED STUDY; CYSTIC FIBROSIS; FLAGELLUM; LUNG INFECTION; MOUSE; NONHUMAN; OPPORTUNISTIC INFECTION; PATHOGENESIS; PHAGOCYTOSIS; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA;

PSEUDOMONAS AERUGINOSA;

EID: 0031975347     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.66.1.43-51.1998     Document Type: Article

References (34)

1. Akerley, B. J., P. A. Cotter, and J. F. Miller. 1995. Ectopic expression of the ftagellar regulon alters development of the Bordetella-host interaction. Cell 80:611-620.
2. Arora, S. K., B. W. Ritchings, E. C. Almira, S. Lory, and R. Ramphal. 1996. Cloning and characterization of Pseudomonas aeruginosa füF, necessary for flagellar assembly and bacterial adherence to mucin, Infect. Immun. 64:2130-2136.
3. Bargouthi, S., K. D. E. Everett, and D. P. Speert. 1995. Nonopsonic phagocytosis of Pseudomonas aeruginosa requires facilitated transport of D-glucose by macrophages. J. Immunol. 154:3420-3428.
4. Brimer, CD, K. Kelly-Wintenberg, and T. C. Montie. 1997. Cloning and characterization of P. aeruginosa a-type flagellin genes, abstr. D-43. In Abstracts of the 97th General Meeting of the American Society for Microbiology 1997. American Society for Microbiology, Washington, D.C.
5. Cormack, B. P., R. H. Valdivia, and S. Falkow. 1996. FACS-optimized mutants of the green fluorescent protein (GFP). Gene 173:33-38.
6. De Bentzmann, S., P. Roger, F. Dupuit, O. Bajolet-Laudinat, C. Fuchey, M. C. Plotkowski, and E. Puchelle. 1996. AsialoGM1 is a receptor for Pseudomonas aeruginosa adherence to regenerating respiratory epithelial cells. Infect. Immun. 64:1582-1588.
7. DiMango, E., H. J. Zar, R. Bryan, and A. Prince. 1995. Diverse Pseudomonas aeruginosa gene products stimulate respiratory epithelial cells to produce interleukin-8. J. Clin. Invest. 96:2204-2210.
8. Drake, D., and T. C. Montie. 1987. Protection against Pseudomonas aeruginosa infection by passive transfer of anti-flagellar serum. Can. J. Microbiol. 33:755-763.
9. Gehring, K., and N. R. Baker. 1994. Evidence for a role of flagella in the binding of Pseudomonas aeruginosa to glycosphingolipid receptors, abstr. D-134. In Abstracts, of the 94th General Meeting of the American Society for Microbiology 1994. American Society for Microbiology, Washington, D.C.
10. Gninert, D. C., C. B. Basbaum, M. J. Welsh, W. E. Finkbeiner, and J. A. Nadel. 1988. Characterization of human tracheal epithelial cells transformed by an origin defection simian virus 40. Proc. Natl. Acad. Sci USA 85:5951-5955.
11. Holder, I. A., R. Wheeler, and T. C. Montie. 1982. Flagellar preparations from Pseudomonas aeruginosa: animal protection studies. Infect. Immun. 35:276-280.
12. Kubesch, P., T. Dork, U. Wulbrand, N. Kalin, T. Neumann, B. Wulf, H. Geerlings, H. Weisbrodt, H. von der Hardt, and B. Tummler. 1993. Genetic determinants of airways' colonization with Pseudomonas aeruginosa in cystic fibrosis. Lancet 341:189-193.
13. Landsperger, W. J., K. D. Kelly-Wintenberg, T. C. Montie, L. S. Knight, M. B. Hansen, C. C. Huntenburg, and M. J. Schneidkraut. 1994. Inhibition of bacterial motility with human antiflagellar monoclonal antibodies atten uates Pseudomonas aeruginosa-induced pneumonia in the immunocompetent rat. Infect. Immun. 62:4825-4830.
14. Luzar, M. A., M. J. Thomassen, and T. C. Montie. 1985. Flagella and motility alterations in Pseudomonas aeruginosa strains from patients with cystic fibrosis: relationship to patient clinical condition. Infect. Immun. 50:577-582.
15. Mahenthiralingam, E., and D. P. Speert. 1995. Nonopsonic phagocytosis of Pseudomonas aeruginosa by macrophages and polymorphonuclear leukocytes requires the presence of the bacterial flagellum. Infect. Immun. 63:4519-4523.
16. Mahenthiralingam, E., M. E. Campbell, and D. P. Speert. 1994. Nonmotility and phagocytic resistance of Pseudomonas aeruginosa isolates from chronically colonized patients with cystic fibrosis. Infect. Immun. 62:596-605.
17. Masduki, A., J. Nakamura, T. Ohga, R. Umezaki, J. Kato, and H. Ohtake. 1995. Isolation and characterization of chemotaxis mutants and genes of Pseudomonas aeruginosa. J. Bacteriol. 177:948-952.
18. Mobley, H. L. T., R. Belas, V. Lockatell, G. Chippendale, A. L. Trifillis, D. E. Johnson, and J. W. Warren. 1996. Construction of a flagellum-negative mutant of Proteus mirabilis: effect on internalization by human renal epithelial cells and virulence in a mouse model of ascending urinary tract infection. Infect. Immun. 64:5332-5340.
19. Montie, T. C., D. Doyle-Huntzinger, R. C. Craven, and I. A. Holder. 1982. Loss of virulence associated with absence of flagellum in an isogenic mutant of Pseudomonas aeruginosa in the burned mouse model. Infect. Immun. 38:1296-1298.
20. Nelson, J. W., M. W. Tredgett, J. K. Sheehan, D. J. Thornton, D. Norman, and J. R. W. Govan. 1990. Mucinophilic and chemotactic properties of Pseudomonas aeruginosa in relation to pulmonary colonization in cystic fibrosis. Infect. Immun. 58:1489-1495.
21. Pier, G. B., G. Meluleni, and J. B. Goldberg. 1995. Clearance of Pseudomonas aeruginosa from the murine gastrointestinal tract is effectively mediated by O-antigen-specific circulating antibodies. Infect. Immun. 63:2818-2825.
22. Richman-Eisensrat, J. B., P. G. Jorens, C. A. Hebert, I. Ueki, and J. A. Nadel. 1993. Interleukin-8: an important chemoattractant in sputum of patients with chronic inflammatory airway disease. Am. J. Physiol. 264 (Lung Cell Mol. Physiol. 8):L413-L418.
23. Saiman, L., and A. Prince. 1993. Pseudomonas aeruginosa pili bind to asialoGM1 which is increased on the surface of cystic fibrosis epithelial cells. J. Clin. Invest. 92:1875-1880.
24. Shapiro, L. 1995. The bacterial flagellum: from genetic network to complex architecture. Cell 80:525-527.
25. Simpson, D. A., R. Ramphal, and S. Lory. 1992. Genetic analysis of Pseudomonas aeniginosa adherence: distinct genetic loci control attachment to epithelial cells and mucins. Infect. Immun. 60:3771-3779.
26. Smith, J. J., S. M. Travis, E. P. Greenberg, and M. J. Welsh. 1996. Cystic fibrosis airway epithelia fail to kill bacteria because of abnormal airway surface fluid. Cell 85:229-236.
27. South, S. L., R. Nichols, and T. C. Montie. 1994. Tyrosine kinase activity in Pseudomonas aeruginosa. Mol. Microbiol. 12:903-910.
28. Spangenberg, C., T. Heuer, C. Burger, and B. Tummler. 1996. Genetic diversity of flagellins of Pseudomonas aeruginosa. FEBS Lett. 396:213-217.
29. Speert, D. P., B. H. Loh, D. A. Cabral, and I. E. Salit. 1986. Nonopsonic phagocytosis of nonmucoid Pseudomonas aeruginosa by human neutrophils and monocyte-derived macrophages is correlated with bacterial piliation and hydrophobicity. Infect. Immun. 53:207-212.
30. Standiford, T. J., S. L. Kunkel, M. A. Basha, et al. 1991. Interleukin-8 gene expression by a pulmonary epithelial cell line. A model for cytokine networks in the lung. J. Clin. Invest. 86:1945-1953.
31. Stanley, P., and L. Siminovitch. 1977. Complementation between mutants of CHO cells resistant to a variety of plant lectins. Somatic Cell Genet. 3:391-405.
32. Starnbauch, M. N., and S. Lory. 1992. The fliA (rpoF) gene of Pseudomonas aeruginosa encodes an alternative sigma factor required for flagellin synthesis. Mol. Microbiol. 6:459-469.
33. Tang, H., M. Kays, and A. Prince. 1995. Role of Pseudomonas aeruginosa pili in acute pulmonary infection. Infect. Immun. 63:1278-1285.
34. Totten, P. A., J. C. Lara, and S. Lory. 1990. The rpoN gene product of Pseudomonas aeruginosa is required for expression of diverse genes, including the flagellin gene. J. Bacteriol. 172:389-396.