메뉴 건너뛰기




Volumn 10, Issue 4, 2015, Pages

Evaluating the SERCA2 and VEGF mRNAs as potential molecular biomarkers of the onset and progression in huntington's disease

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; MESSENGER RNA; PMCA1 PROTEIN; SARCO ENDOPLASMIC RETICULUM ASSOCIATED ATP2A2 CALCIUM PUMP; SARCO ENDOPLASMIC RETICULUM ASSOCIATED ATP2A3 CALCIUM PUMP; UNCLASSIFIED DRUG; VASCULOTROPIN; ATP2A2 PROTEIN, HUMAN; CALCIUM; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

EID: 84928638818     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0125259     Document Type: Article
Times cited : (18)

References (62)
  • 2
    • 1542674455 scopus 로고    scopus 로고
    • Huntingtin: Alive and well and working in middle management
    • MacDonald ME. Huntingtin: alive and well and working in middle management. Sci STKE 2003; pe48.
    • (2003) Sci STKE , pp. pe48
    • MacDonald, M.E.1
  • 3
    • 0027480960 scopus 로고
    • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
    • PMID: 8458085
    • The Huntington's Disease Collaborative Research Group. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 1993; 72: 971-983. PMID: 8458085
    • (1993) Cell , vol.72 , pp. 971-983
  • 4
    • 0034571171 scopus 로고    scopus 로고
    • Huntington's disease: The challenge for cell biologists
    • PMID: 11121745
    • Tobin AJ, Signer ER. Huntington's disease: the challenge for cell biologists. Trends Cell Biol. 2000; 10: 531-536. PMID: 11121745
    • (2000) Trends Cell Biol , vol.10 , pp. 531-536
    • Tobin, A.J.1    Signer, E.R.2
  • 5
    • 0037194897 scopus 로고    scopus 로고
    • Polyglutamine pathogenesis: Emergence of unifying mechanisms for Huntington's disease and related disorders
    • PMID: 12372277
    • Ross CA. Polyglutamine pathogenesis: emergence of unifying mechanisms for Huntington's disease and related disorders. Neuron 2002; 35: 819-822. PMID: 12372277
    • (2002) Neuron , vol.35 , pp. 819-822
    • Ross, C.A.1
  • 6
    • 0041656292 scopus 로고    scopus 로고
    • The hunt for huntingtin function: Interaction partners tell many different stories
    • PMID: 12932731
    • Harjes P, Wanker EE. The hunt for huntingtin function: interaction partners tell many different stories. Trends Biochem Sci. 2003; 28: 425-433. PMID: 12932731
    • (2003) Trends Biochem Sci , vol.28 , pp. 425-433
    • Harjes, P.1    Wanker, E.E.2
  • 7
    • 0142123112 scopus 로고    scopus 로고
    • Microtubule destabilization and nuclear entry are sequential steps leading to toxicity in Huntington's disease
    • PMID: 14527999
    • Trushina E, Heldebrant MP, Perez-Terzic CM, Bortolon R, Kovtun IV, Badger JD, et al. Microtubule destabilization and nuclear entry are sequential steps leading to toxicity in Huntington's disease. Proc Natl Acad Sci U S A 2003; 100: 12171-12176. PMID: 14527999
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 12171-12176
    • Trushina, E.1    Heldebrant, M.P.2    Perez-Terzic, C.M.3    Bortolon, R.4    Kovtun, I.V.5    Badger, J.D.6
  • 8
    • 0037408279 scopus 로고    scopus 로고
    • Transcriptional abnormalities in Huntington disease
    • PMID: 12711212
    • Sugars KL, Rubinsztein DC. Transcriptional abnormalities in Huntington disease. Trends Genet. 2003; 19: 233-238. PMID: 12711212
    • (2003) Trends Genet , vol.19 , pp. 233-238
    • Sugars, K.L.1    Rubinsztein, D.C.2
  • 9
    • 4444302167 scopus 로고    scopus 로고
    • Deranged neuronal calcium signaling and Huntington disease
    • PMID: 15336977
    • Bezprozvanny I, Hayden MR. Deranged neuronal calcium signaling and Huntington disease. Biochem Biophys Res Commun. 2004; 322: 1310-1317. PMID: 15336977
    • (2004) Biochem Biophys Res Commun , vol.322 , pp. 1310-1317
    • Bezprozvanny, I.1    Hayden, M.R.2
  • 10
    • 13944275615 scopus 로고    scopus 로고
    • Polyglutamine expansion of huntingtin impairs its nuclear export
    • PMID: 15654337
    • Cornett J, Cao F, Wang CE, Ross CA, Bates GP, Li SH, et al. Polyglutamine expansion of huntingtin impairs its nuclear export. Nat Genet. 2005; 37: 198-204. PMID: 15654337
    • (2005) Nat Genet , vol.37 , pp. 198-204
    • Cornett, J.1    Cao, F.2    Wang, C.E.3    Ross, C.A.4    Bates, G.P.5    Li, S.H.6
  • 11
    • 34248166420 scopus 로고    scopus 로고
    • Multiple pathways contribute to the pathogenesis of Huntington disease
    • PMID: 17173700
    • Li S, Li XJ. Multiple pathways contribute to the pathogenesis of Huntington disease. Mol Neurodegener. 2006; 1: 19. PMID: 17173700
    • (2006) Mol Neurodegener , vol.1 , pp. 19
    • Li, S.1    Li, X.J.2
  • 12
    • 33749042331 scopus 로고    scopus 로고
    • Transcriptional repression of PGC-1 alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration
    • PMID: 17018277
    • Cui L, Jeong H, Borovecki F, Parkhurst CN, Tanese N, Krainc D. Transcriptional repression of PGC-1 alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration. Cell 2006; 127: 59-69. PMID: 17018277
    • (2006) Cell , vol.127 , pp. 59-69
    • Cui, L.1    Jeong, H.2    Borovecki, F.3    Parkhurst, C.N.4    Tanese, N.5    Krainc, D.6
  • 13
    • 34247158550 scopus 로고    scopus 로고
    • Oxidative stress and mitochondrial dysfunction in neurodegenerative diseases
    • PMID: 17303344
    • Trushina E, McMurray CT. Oxidative stress and mitochondrial dysfunction in neurodegenerative diseases. Neuroscience 2007; 145: 1233-1248. PMID: 17303344
    • (2007) Neuroscience , vol.145 , pp. 1233-1248
    • Trushina, E.1    McMurray, C.T.2
  • 14
    • 34047100940 scopus 로고    scopus 로고
    • N-methyl-D-aspartate (NMDA) receptor function and excitotoxicity in Huntington's disease
    • PMID: 17188796
    • Fan MM, Raymond LA. N-methyl-D-aspartate (NMDA) receptor function and excitotoxicity in Huntington's disease. Prog Neurobiol. 2007; 81: 272-293. PMID: 17188796
    • (2007) Prog Neurobiol , vol.81 , pp. 272-293
    • Fan, M.M.1    Raymond, L.A.2
  • 15
    • 63849154126 scopus 로고    scopus 로고
    • In vivo evidence for NMDA receptor-mediated excitotoxicity in a murine genetic model of Huntington disease
    • PMID: 19279257
    • Heng MY, Detloff PJ, Wang PL, Tsien JZ, Albin RL. In vivo evidence for NMDA receptor-mediated excitotoxicity in a murine genetic model of Huntington disease. J Neurosci. 2009; 29: 3200-3205. doi: 10.1523/JNEUROSCI.5599-08.2009 PMID: 19279257
    • (2009) J Neurosci , vol.29 , pp. 3200-3205
    • Heng, M.Y.1    Detloff, P.J.2    Wang, P.L.3    Tsien, J.Z.4    Albin, R.L.5
  • 17
    • 84894080255 scopus 로고    scopus 로고
    • Gene expression profile in fibroblasts of Huntington's disease patients and controls
    • PMID: 24296361
    • Marchina E, Misasi S, Bozzato A, Ferraboli S, Agosti C, Rozzini L, et al. Gene expression profile in fibroblasts of Huntington's disease patients and controls. J Neurol Sci. 2014; 337: 42-46. doi: 10.1016/j.jns.2013.11.014 PMID: 24296361
    • (2014) J Neurol Sci , vol.337 , pp. 42-46
    • Marchina, E.1    Misasi, S.2    Bozzato, A.3    Ferraboli, S.4    Agosti, C.5    Rozzini, L.6
  • 18
    • 23344448837 scopus 로고    scopus 로고
    • Genome-wide expression profiling of human blood reveals biomarkers for Huntington's disease
    • PMID: 16043692
    • Borovecki F, Lovrecic L, Zhou J, Jeong H, Then F, Rosas HD, et al. Genome-wide expression profiling of human blood reveals biomarkers for Huntington's disease. Proc Natl Acad Sci U S A 2005; 102: 11023-11028. PMID: 16043692
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 11023-11028
    • Borovecki, F.1    Lovrecic, L.2    Zhou, J.3    Jeong, H.4    Then, F.5    Rosas, H.D.6
  • 19
    • 35448968328 scopus 로고    scopus 로고
    • Analysis of potential transcriptomic biomarkers for Huntington's disease in peripheral blood
    • PMID: 17724341
    • Runne H, Kuhn A, Wild EJ, Pratyaksha W, Kristiansen M, Isaacs JD, et al. Analysis of potential transcriptomic biomarkers for Huntington's disease in peripheral blood. Proc Natl Acad Sci U S A 2007; 104: 14424-14429. PMID: 17724341
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 14424-14429
    • Runne, H.1    Kuhn, A.2    Wild, E.J.3    Pratyaksha, W.4    Kristiansen, M.5    Isaacs, J.D.6
  • 20
    • 72849144063 scopus 로고    scopus 로고
    • Gene expression changes in blood as a putative biomarker for Huntington's disease
    • PMID: 19844910
    • Lovrecic L, Kastrin A, Kobal J, Pirtosek Z, Krainc D, Peterlin B. Gene expression changes in blood as a putative biomarker for Huntington's disease. Mov Disord. 2009; 24: 2277-2281. doi: 10.1002/mds.22477 PMID: 19844910
    • (2009) Mov Disord , vol.24 , pp. 2277-2281
    • Lovrecic, L.1    Kastrin, A.2    Kobal, J.3    Pirtosek, Z.4    Krainc, D.5    Peterlin, B.6
  • 21
    • 84866925330 scopus 로고    scopus 로고
    • Downregulation of genes involved in metabolism and oxidative stress in the peripheral leukocytes of Huntington's disease patients
    • PMID: 23029535
    • Chang KH, Chen YC, Wu YR, Lee WF, Chen CM. Downregulation of genes involved in metabolism and oxidative stress in the peripheral leukocytes of Huntington's disease patients. PLoSOne 2012; 7: e46492. doi: 10.1371/journal.pone.0046492 PMID: 23029535
    • (2012) PLoSOne , vol.7 , pp. e46492
    • Chang, K.H.1    Chen, Y.C.2    Wu, Y.R.3    Lee, W.F.4    Chen, C.M.5
  • 22
    • 84865112006 scopus 로고    scopus 로고
    • Oxidative stress and inflammation biomarkers in the blood of patients with Huntington's disease
    • PMID: 22889672
    • Sanchez-Lopez F, Tasset I, Aguera E, Feijoo M, Fernandez-Bolanos R, Sánchez FM, et al. Oxidative stress and inflammation biomarkers in the blood of patients with Huntington's disease. Neurol Res. 2012; 34: 721-724. doi: 10.1179/1743132812Y.0000000073 PMID: 22889672
    • (2012) Neurol Res , vol.34 , pp. 721-724
    • Sanchez-Lopez, F.1    Tasset, I.2    Aguera, E.3    Feijoo, M.4    Fernandez-Bolanos, R.5    Sánchez, F.M.6
  • 23
    • 84874111802 scopus 로고    scopus 로고
    • A study of molecular changes relating to energy metabolism and cellular stress in people with Huntington's disease: Looking for biomarkers
    • PMID: 23070563
    • Krzyszton-Russjan J, Zielonka D, Jackiewicz J, Kusmirek S, Bubko I, Klimberg A, et al. A study of molecular changes relating to energy metabolism and cellular stress in people with Huntington's disease: looking for biomarkers. J Bioenerg Biomembr. 2013; 45: 71-85. doi: 10.1007/s10863-012-9479-3 PMID: 23070563
    • (2013) J Bioenerg Biomembr , vol.45 , pp. 71-85
    • Krzyszton-Russjan, J.1    Zielonka, D.2    Jackiewicz, J.3    Kusmirek, S.4    Bubko, I.5    Klimberg, A.6
  • 24
    • 84928641662 scopus 로고    scopus 로고
    • Whole gene expression profile in blood reveals multiple pathways deregulation in R6/2 mouse model
    • PMID: 24252798
    • Diamanti D, Mori E, Incarnato D, Malusa F, Fondelli C, Magnoni L, et al. Whole gene expression profile in blood reveals multiple pathways deregulation in R6/2 mouse model. Biomark Res. 2013; 1: 28. doi: 10.1186/2050-7771-1-28 PMID: 24252798
    • (2013) Biomark Res , vol.1 , pp. 28
    • Diamanti, D.1    Mori, E.2    Incarnato, D.3    Malusa, F.4    Fondelli, C.5    Magnoni, L.6
  • 25
    • 61849142791 scopus 로고    scopus 로고
    • Calcium signaling and neurodegenerative diseases
    • PMID: 19230774
    • Bezprozvanny I. Calcium signaling and neurodegenerative diseases. Trends Mol Med. 2009; 15: 89-100. doi: 10.1016/j.molmed.2009.01.001 PMID: 19230774
    • (2009) Trends Mol Med , vol.15 , pp. 89-100
    • Bezprozvanny, I.1
  • 26
    • 0035816627 scopus 로고    scopus 로고
    • Polyglutamine-expanded huntingtin promotes sensitization of N-methyl-D-aspartate receptors via post-synaptic density 95
    • PMID: 11319238
    • Sun Y, Savanenin A, Reddy PH, Liu YF. Polyglutamine-expanded huntingtin promotes sensitization of N-methyl-D-aspartate receptors via post-synaptic density 95. J Biol Chem. 2001; 276: 24713-24718. PMID: 11319238
    • (2001) J Biol Chem , vol.276 , pp. 24713-24718
    • Sun, Y.1    Savanenin, A.2    Reddy, P.H.3    Liu, Y.F.4
  • 27
    • 0037075624 scopus 로고    scopus 로고
    • Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease
    • PMID: 11906693
    • Zeron MM, Hansson O, Chen N, Wellington CL, Leavitt BR, Brundin P, et al. Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease. Neuron 2002; 33: 849-860. PMID: 11906693
    • (2002) Neuron , vol.33 , pp. 849-860
    • Zeron, M.M.1    Hansson, O.2    Chen, N.3    Wellington, C.L.4    Leavitt, B.R.5    Brundin, P.6
  • 28
    • 0042357138 scopus 로고    scopus 로고
    • Expression of polyglutamine-expanded huntingtin induces tyrosine phosphorylation of N-methyl-D-aspartate receptors
    • PMID: 12810713
    • Song C, Zhang Y, Parsons CG, Liu YF. Expression of polyglutamine-expanded huntingtin induces tyrosine phosphorylation of N-methyl-D-aspartate receptors. J Biol Chem. 2003; 278: 33364-33369 PMID: 12810713
    • (2003) J Biol Chem , vol.278 , pp. 33364-33369
    • Song, C.1    Zhang, Y.2    Parsons, C.G.3    Liu, Y.F.4
  • 29
    • 30744437894 scopus 로고    scopus 로고
    • Striatal neuronal apoptosis is preferentially enhanced by NMDA receptor activation in YAC transgenic mouse model of Huntington disease
    • PMID: 16165367
    • Shehadeh J, Fernandes HB, Zeron Mullins MM, Graham RK, Leavitt BR, Hayden MR, et al. Striatal neuronal apoptosis is preferentially enhanced by NMDA receptor activation in YAC transgenic mouse model of Huntington disease. Neurobiol Dis. 2006; 21: 392-403. PMID: 16165367
    • (2006) Neurobiol Dis , vol.21 , pp. 392-403
    • Shehadeh, J.1    Fernandes, H.B.2    Zeron Mullins, M.M.3    Graham, R.K.4    Leavitt, B.R.5    Hayden, M.R.6
  • 30
    • 34147112751 scopus 로고    scopus 로고
    • Altered NMDA receptor trafficking in a yeast artificial chromosome transgenic mouse model of Huntington's disease
    • PMID: 17409241
    • Fan MM, Fernandes HB, Zhang LY, Hayden MR, Raymond LA. Altered NMDA receptor trafficking in a yeast artificial chromosome transgenic mouse model of Huntington's disease. J Neurosci. 2007; 27: 3768-3779. PMID: 17409241
    • (2007) J Neurosci , vol.27 , pp. 3768-3779
    • Fan, M.M.1    Fernandes, H.B.2    Zhang, L.Y.3    Hayden, M.R.4    Raymond, L.A.5
  • 31
    • 0041963057 scopus 로고    scopus 로고
    • Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1
    • PMID: 12873381
    • Tang TS, Tu H, Chan EY, Maximov A, Wang Z, Wellington CL, et al. Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1. Neuron 2003; 39: 227-239. PMID: 12873381
    • (2003) Neuron , vol.39 , pp. 227-239
    • Tang, T.S.1    Tu, H.2    Chan, E.Y.3    Maximov, A.4    Wang, Z.5    Wellington, C.L.6
  • 32
    • 14044264256 scopus 로고    scopus 로고
    • Disturbed Ca2+ signaling and apoptosis of medium spiny neurons in Huntington's disease
    • PMID: 15695335
    • Tang TS, Slow E, Lupu V, Stavrovskaya IG, Sugimori M, Llinás R, et al. Disturbed Ca2+ signaling and apoptosis of medium spiny neurons in Huntington's disease. Proc Natl Acad Sci U S A 2005; 102: 2602-2607. PMID: 15695335
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 2602-2607
    • Tang, T.S.1    Slow, E.2    Lupu, V.3    Stavrovskaya, I.G.4    Sugimori, M.5    Llinás, R.6
  • 33
    • 84888331632 scopus 로고    scopus 로고
    • Expression of genes encoding the calcium signalosome in cellular and transgenic models of Huntington's disease
    • PMID: 24324398
    • Czeredys M, Gruszczynska-Biegala J, Schacht T, Methner A, Kuznicki J. Expression of genes encoding the calcium signalosome in cellular and transgenic models of Huntington's disease. Front Mol Neurosci. 2013; 6: 42. doi: 10.3389/fnmol.2013.00042 PMID: 24324398
    • (2013) Front Mol Neurosci , vol.6 , pp. 42
    • Czeredys, M.1    Gruszczynska-Biegala, J.2    Schacht, T.3    Methner, A.4    Kuznicki, J.5
  • 34
    • 84862948326 scopus 로고    scopus 로고
    • Regulation and molecular mechanisms of calcium transport genes: Do they play a role in calcium transport in the uterine endometrium?
    • PMID: 22204796
    • Choi KC, An BS, Yang H, Jeung EB. Regulation and molecular mechanisms of calcium transport genes: do they play a role in calcium transport in the uterine endometrium? J Physiol Pharmacol. 2011; 62: 499-504. PMID: 22204796
    • (2011) J Physiol Pharmacol , vol.62 , pp. 499-504
    • Choi, K.C.1    An, B.S.2    Yang, H.3    Jeung, E.B.4
  • 35
    • 34248586471 scopus 로고    scopus 로고
    • Distinct phenotypes among plasma membrane Ca2+-ATPase knockout mice
    • PMID: 17446468
    • Prasad V, Okunade G, Liu L, Paul RJ, Shull GE. Distinct phenotypes among plasma membrane Ca2+-ATPase knockout mice. Ann N Y Acad Sci. 2007; 1099: 276-286. PMID: 17446468
    • (2007) Ann N y Acad Sci , vol.1099 , pp. 276-286
    • Prasad, V.1    Okunade, G.2    Liu, L.3    Paul, R.J.4    Shull, G.E.5
  • 36
    • 17344367099 scopus 로고    scopus 로고
    • The neuroprotective function of vascular endothelial growth factor (VEGF)
    • PMID: 15827888
    • Gora-Kupilas K, Josko J. The neuroprotective function of vascular endothelial growth factor (VEGF). Folia Neuropathol. 2005; 43: 31-39. PMID: 15827888
    • (2005) Folia Neuropathol , vol.43 , pp. 31-39
    • Gora-Kupilas, K.1    Josko, J.2
  • 37
    • 84884997788 scopus 로고    scopus 로고
    • Dose-dependent neuroprotection of VEGF(1)(6)(5) in Huntington's disease striatum
    • PMID: 23799534
    • Ellison SM, Trabalza A, Tisato V, Pazarentzos E, Lee S, Papadaki V, et al. Dose-dependent neuroprotection of VEGF(1)(6)(5) in Huntington's disease striatum. Mol Ther. 2013; 21: 1862-1875. doi: 10.1038/mt.2013.132 PMID: 23799534
    • (2013) Mol Ther , vol.21 , pp. 1862-1875
    • Ellison, S.M.1    Trabalza, A.2    Tisato, V.3    Pazarentzos, E.4    Lee, S.5    Papadaki, V.6
  • 38
    • 0034699326 scopus 로고    scopus 로고
    • Hypoxia-induced VEGF enhances tumor survivability via suppression of serum deprivation-induced apoptosis
    • PMID: 11030151
    • Baek JH, Jang JE, Kang CM, Chung HY, Kim ND, Kim KW. Hypoxia-induced VEGF enhances tumor survivability via suppression of serum deprivation-induced apoptosis. Oncogene 2000; 19: 4621-4631. PMID: 11030151
    • (2000) Oncogene , vol.19 , pp. 4621-4631
    • Baek, J.H.1    Jang, J.E.2    Kang, C.M.3    Chung, H.Y.4    Kim, N.D.5    Kim, K.W.6
  • 39
    • 0035842544 scopus 로고    scopus 로고
    • Caspase-3 and the regulation of hypoxic neuronal death by vascular endothelial growth factor
    • PMID: 11734367
    • Jin K, Mao XO, Batteur SP, McEachron E, Leahy A, Greenberg DA. Caspase-3 and the regulation of hypoxic neuronal death by vascular endothelial growth factor. Neuroscience 2001; 108: 351-358. PMID: 11734367
    • (2001) Neuroscience , vol.108 , pp. 351-358
    • Jin, K.1    Mao, X.O.2    Batteur, S.P.3    McEachron, E.4    Leahy, A.5    Greenberg, D.A.6
  • 40
    • 0000481740 scopus 로고    scopus 로고
    • Vascular endothelial growth factor: Direct neuroprotective effect in in vitro ischemia
    • PMID: 10963684
    • Jin KL, Mao XO, Greenberg DA. Vascular endothelial growth factor: direct neuroprotective effect in in vitro ischemia. Proc Natl Acad Sci U S A 2000; 97: 10242-10247. PMID: 10963684
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 10242-10247
    • Jin, K.L.1    Mao, X.O.2    Greenberg, D.A.3
  • 41
    • 0037015059 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo
    • PMID: 12181492
    • Jin K, Zhu Y, Sun Y, Mao XO, Xie L, Greenberg DA. Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo. Proc Natl Acad Sci U S A 2002; 99: 11946-11950. PMID: 12181492
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 11946-11950
    • Jin, K.1    Zhu, Y.2    Sun, Y.3    Mao, X.O.4    Xie, L.5    Greenberg, D.A.6
  • 42
    • 0034978562 scopus 로고    scopus 로고
    • Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration
    • PMID: 11381259
    • Oosthuyse B, Moons L, Storkebaum E, Beck H, Nuyens D, Brusselmans K, et al. Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration. Nat Genet. 2001; 28: 131-138. PMID: 11381259
    • (2001) Nat Genet , vol.28 , pp. 131-138
    • Oosthuyse, B.1    Moons, L.2    Storkebaum, E.3    Beck, H.4    Nuyens, D.5    Brusselmans, K.6
  • 43
    • 0041743159 scopus 로고    scopus 로고
    • VEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia
    • PMID: 12813020
    • Sun Y, Jin K, Xie L, Childs J, Mao XO, Logvinova A, et al. VEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia. J Clin Invest. 2003; 111: 1843-1851. PMID: 12813020
    • (2003) J Clin Invest , vol.111 , pp. 1843-1851
    • Sun, Y.1    Jin, K.2    Xie, L.3    Childs, J.4    Mao, X.O.5    Logvinova, A.6
  • 44
    • 0032782809 scopus 로고    scopus 로고
    • Inverse correlation between apoptotic (Fas ligand, caspase-3) and angiogenic factors (VEGF, microvessel density) in squamous cell lung carcinomas
    • PMID: 10470099
    • Volm M, Mattern J, Koomagi R. Inverse correlation between apoptotic (Fas ligand, caspase-3) and angiogenic factors (VEGF, microvessel density) in squamous cell lung carcinomas. Anticancer Res. 1999; 19: 1669-1671. PMID: 10470099
    • (1999) Anticancer Res , vol.19 , pp. 1669-1671
    • Volm, M.1    Mattern, J.2    Koomagi, R.3
  • 45
    • 0037308174 scopus 로고    scopus 로고
    • Vascular endothelial growth factor promotes proliferation of cortical neuron precursors by regulating E2F expression
    • PMID: 12554697
    • Zhu Y, Jin K, Mao XO, Greenberg DA. Vascular endothelial growth factor promotes proliferation of cortical neuron precursors by regulating E2F expression. Faseb j. 2003; 17: 186-193. PMID: 12554697
    • (2003) Faseb J , vol.17 , pp. 186-193
    • Zhu, Y.1    Jin, K.2    Mao, X.O.3    Greenberg, D.A.4
  • 46
    • 0029558465 scopus 로고
    • Brain glucose uptake and unawareness of hypoglycemia in patients with insulin-dependent diabetes mellitus
    • PMID: 7491135
    • Boyle PJ, Kempers SF, O'Connor AM, Nagy RJ. Brain glucose uptake and unawareness of hypoglycemia in patients with insulin-dependent diabetes mellitus. N Engl J Med. 1995; 333: 1726-1731. PMID: 7491135
    • (1995) N Engl J Med , vol.333 , pp. 1726-1731
    • Boyle, P.J.1    Kempers, S.F.2    O'Connor, A.M.3    Nagy, R.J.4
  • 48
    • 0032559597 scopus 로고    scopus 로고
    • Vascular endothelial growth factor induces endothelial fenestrations in vitro
    • PMID: 9472045
    • Esser S, Wolburg K, Wolburg H, Breier G, Kurzchalia T, Risau W. Vascular endothelial growth factor induces endothelial fenestrations in vitro. J Cell Biol. 1998; 140: 947-959. PMID: 9472045
    • (1998) J Cell Biol , vol.140 , pp. 947-959
    • Esser, S.1    Wolburg, K.2    Wolburg, H.3    Breier, G.4    Kurzchalia, T.5    Risau, W.6
  • 49
    • 0032937146 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and its receptor, KDR, in human brain tissue after ischemic stroke
    • PMID: 10211994
    • Issa R, Krupinski J, Bujny T, Kumar S, Kaluza J, Kumar P. Vascular endothelial growth factor and its receptor, KDR, in human brain tissue after ischemic stroke. Lab Invest. 1999; 79: 417-425. PMID: 10211994
    • (1999) Lab Invest , vol.79 , pp. 417-425
    • Issa, R.1    Krupinski, J.2    Bujny, T.3    Kumar, S.4    Kaluza, J.5    Kumar, P.6
  • 50
    • 0028809505 scopus 로고
    • Upregulation of blood-brain barrier GLUT1 glucose transporter protein and mRNA in experimental chronic hypoglycemia
    • PMID: 7589845
    • Kumagai AK, Kang YS, Boado RJ, Pardridge WM. Upregulation of blood-brain barrier GLUT1 glucose transporter protein and mRNA in experimental chronic hypoglycemia. Diabetes 1995; 44: 1399-1404. PMID: 7589845
    • (1995) Diabetes , vol.44 , pp. 1399-1404
    • Kumagai, A.K.1    Kang, Y.S.2    Boado, R.J.3    Pardridge, W.M.4
  • 51
    • 0032926784 scopus 로고    scopus 로고
    • Macrophage infiltration and heme oxygenase-1 expression correlate with angiogenesis in human gliomas
    • PMID: 10353745
    • Nishie A, Ono M, Shono T, Fukushi J, Otsubo M, Onoue H, et al. Macrophage infiltration and heme oxygenase-1 expression correlate with angiogenesis in human gliomas. Clin Cancer Res. 1999; 5: 1107-1113. PMID: 10353745
    • (1999) Clin Cancer Res , vol.5 , pp. 1107-1113
    • Nishie, A.1    Ono, M.2    Shono, T.3    Fukushi, J.4    Otsubo, M.5    Onoue, H.6
  • 52
    • 0024994317 scopus 로고
    • Regulation of hexose transport in aortic endothelial cells by vascular permeability factor and tumor necrosis factor-alpha, but not by insulin
    • PMID: 2211680
    • Pekala P, Marlow M, Heuvelman D, Connolly D. Regulation of hexose transport in aortic endothelial cells by vascular permeability factor and tumor necrosis factor-alpha, but not by insulin. J Biol Chem. 1990; 265: 18051-18054. PMID: 2211680
    • (1990) J Biol Chem , vol.265 , pp. 18051-18054
    • Pekala, P.1    Marlow, M.2    Heuvelman, D.3    Connolly, D.4
  • 53
    • 0034043043 scopus 로고    scopus 로고
    • Enhancement of glucose transport by vascular endothelial growth factor in retinal endothelial cells
    • PMID: 10845612
    • Sone H, Deo BK, Kumagai AK. Enhancement of glucose transport by vascular endothelial growth factor in retinal endothelial cells. Invest Ophthalmol Vis Sci. 2000; 41: 1876-1884. PMID: 10845612
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , pp. 1876-1884
    • Sone, H.1    Deo, B.K.2    Kumagai, A.K.3
  • 54
    • 0027275819 scopus 로고
    • A new polymerase chain reaction (PCR) assay for the trinucleotide repeat that is unstable and expanded on Huntington's disease chromosomes
    • PMID: 8366869
    • Warner JP, Barron LH, Brock DJ. A new polymerase chain reaction (PCR) assay for the trinucleotide repeat that is unstable and expanded on Huntington's disease chromosomes. Mol Cell Probes 1993; 7: 235-239. PMID: 8366869
    • (1993) Mol Cell Probes , vol.7 , pp. 235-239
    • Warner, J.P.1    Barron, L.H.2    Brock, D.J.3
  • 55
    • 84876675051 scopus 로고    scopus 로고
    • EMQN/CMGS best practice guidelines for the molecular genetic testing of Huntington disease
    • PMID: 22990145
    • Losekoot M, van Belzen MJ, Seneca S, Bauer P, Stenhouse SA, Barton DE, et al. EMQN/CMGS best practice guidelines for the molecular genetic testing of Huntington disease. Eur J Hum Genet. 2013; 21: 480-486 doi: 10.1038/ejhg.2012.200 PMID: 22990145
    • (2013) Eur J Hum Genet , vol.21 , pp. 480-486
    • Losekoot, M.1    Van Belzen, M.J.2    Seneca, S.3    Bauer, P.4    Stenhouse, S.A.5    Barton, D.E.6
  • 56
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method
    • PMID: 11846609
    • Livak JK, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method. Methods 2001; 25: 402-408. PMID: 11846609
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, J.K.1    Schmittgen, T.D.2
  • 57
    • 0036051068 scopus 로고    scopus 로고
    • Cardiovascular ageing in health sets the stage for cardiovascular disease
    • PMID: 16352074
    • Lakatta EG. Cardiovascular ageing in health sets the stage for cardiovascular disease. Heart Lung Circ. 2002; 11: 76-91. PMID: 16352074
    • (2002) Heart Lung Circ , vol.11 , pp. 76-91
    • Lakatta, E.G.1
  • 58
    • 0027320195 scopus 로고
    • Normal and hypertrophied senescent rat heart: Mechanical and molecular characteristics
    • PMID: 8342633
    • Besse S, Assayag P, Delcayre C, Carre F, Cheav SL, Lecarpentier Y, et al. Normal and hypertrophied senescent rat heart: mechanical and molecular characteristics. Am J Physiol. 1993; 265: H183-190. PMID: 8342633
    • (1993) Am J Physiol , vol.265 , pp. H183-H190
    • Besse, S.1    Assayag, P.2    Delcayre, C.3    Carre, F.4    Cheav, S.L.5    Lecarpentier, Y.6
  • 59
    • 33744489068 scopus 로고    scopus 로고
    • Cardiac overexpression of alcohol dehydrogenase (ADH) alleviates aging-associated cardiomyocyte contractile dysfunction: Role of intracellular Ca2+ cycling proteins
    • PMID: 16842498
    • Guo KK, Ren J. Cardiac overexpression of alcohol dehydrogenase (ADH) alleviates aging-associated cardiomyocyte contractile dysfunction: role of intracellular Ca2+ cycling proteins. Aging Cell 2006; 5: 259-265 PMID: 16842498
    • (2006) Aging Cell , vol.5 , pp. 259-265
    • Guo, K.K.1    Ren, J.2
  • 60
    • 33845204316 scopus 로고    scopus 로고
    • Regulation of sarco/endoplasmic and plasma membrane calcium ATPase gene expression by calcium in cultured human lens epithelial cells
    • PMID: 16875731
    • Marian MJ, Mukhopadhyay P, Borchman D, Tang D, Paterson CA. Regulation of sarco/endoplasmic and plasma membrane calcium ATPase gene expression by calcium in cultured human lens epithelial cells. Cell Calcium 2007; 41: 87-95. PMID: 16875731
    • (2007) Cell Calcium , vol.41 , pp. 87-95
    • Marian, M.J.1    Mukhopadhyay, P.2    Borchman, D.3    Tang, D.4    Paterson, C.A.5
  • 61
    • 47049102553 scopus 로고    scopus 로고
    • The plasma membrane Ca2+ ATPase of animal cells: Structure, function and regulation
    • PMID: 18328800
    • Di Leva F, Domi T, Fedrizzi L, Lim D, Carafoli E. The plasma membrane Ca2+ ATPase of animal cells: structure, function and regulation. Arch Biochem Biophys 2008; 476: 65-74. doi: 10.1016/j.abb.2008.02.026 PMID: 18328800
    • (2008) Arch Biochem Biophys , vol.476 , pp. 65-74
    • Di Leva, F.1    Domi, T.2    Fedrizzi, L.3    Lim, D.4    Carafoli, E.5
  • 62
    • 54849422301 scopus 로고    scopus 로고
    • Huntingtin modulates transcription, occupies gene promoters in vivo, and binds directly to DNA in a polyglutamine-dependent manner
    • PMID: 18923047
    • Benn CL, Sun T, Sadri-Vakili G, McFarland KN, DiRocco DP, Yohrling GJ, et al. Huntingtin modulates transcription, occupies gene promoters in vivo, and binds directly to DNA in a polyglutamine-dependent manner. The Journal of Neurosciences 2008; 28(42): 10720-10733. doi: 10.1523/JNEUROSCI.2126-08.2008 PMID: 18923047
    • (2008) The Journal of Neurosciences , vol.28 , Issue.42 , pp. 10720-10733
    • Benn, C.L.1    Sun, T.2    Sadri-Vakili, G.3    McFarland, K.N.4    DiRocco, D.P.5    Yohrling, G.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.