메뉴 건너뛰기




Volumn 6, Issue NOV, 2013, Pages

Expression of genes encoding the calcium signalosome in cellular and transgenic models of Huntington's disease

Author keywords

Calcium signalosome; Calcyclin binding protein; Huntingtin; Huntingtin associated protein 1; Huntington's disease; Store operated calcium entry; Taqman low density arrays; Transgenic mice

Indexed keywords

AMYLOID PRECURSOR PROTEIN; CALRETININ; HUNTINGTIN; PRESENILIN 2; SEPTIN;

EID: 84888331632     PISSN: 16625099     EISSN: None     Source Type: Journal    
DOI: 10.3389/fnmol.2013.00042     Document Type: Article
Times cited : (40)

References (84)
  • 1
    • 0037947662 scopus 로고    scopus 로고
    • A cell-based assay for aggregation inhibitors as therapeutics of polyglutaminerepeat disease and validation in Drosophila
    • doi: 10.1073/pnas.2628045100
    • Apostol, B. L., Kazantsev, A., Raffioni, S., Illes, K., Pallos, J., Bodai, L., et al. (2003). A cell-based assay for aggregation inhibitors as therapeutics of polyglutaminerepeat disease and validation in Drosophila. Proc. Natl. Acad. Sci. U.S.A. 100, 5950-5955. doi: 10.1073/pnas.2628045100
    • (2003) Proc. Natl. Acad. Sci. U.S.A , vol.100 , pp. 5950-5955
    • Apostol, B.L.1    Kazantsev, A.2    Raffioni, S.3    Illes, K.4    Pallos, J.5    Bodai, L.6
  • 2
    • 0030001072 scopus 로고    scopus 로고
    • Expansion of polyglutamine repeat in huntingtin leads to abnormal protein interactions involving calmodulin
    • doi: 10.1073/pnas.93.10.5037
    • Bao, J., Sharp, A. H., Wagster, M. V., Becher, M., Schilling, G., Ross, C. A., et al. (1996). Expansion of polyglutamine repeat in huntingtin leads to abnormal protein interactions involving calmodulin. Proc. Natl. Acad. Sci. U.S.A. 93, 5037-5042. doi: 10.1073/pnas.93.10.5037
    • (1996) Proc. Natl. Acad. Sci. U.S.A , vol.93 , pp. 5037-5042
    • Bao, J.1    Sharp, A.H.2    Wagster, M.V.3    Becher, M.4    Schilling, G.5    Ross, C.A.6
  • 3
    • 0029861417 scopus 로고    scopus 로고
    • The GTPase-activating protein RGS4 stabilizes the transition state for nucleotide hydrolysis
    • doi: 10.1074/jbc.271.44.27209
    • Berman, D. M., Kozasa, T., and Gilman, A. G. (1996). The GTPase-activating protein RGS4 stabilizes the transition state for nucleotide hydrolysis. J. Biol. Chem. 271, 27209-27212. doi: 10.1074/jbc.271.44.27209
    • (1996) J. Biol. Chem , vol.271 , pp. 27209-27212
    • Berman, D.M.1    Kozasa, T.2    Gilman, A.G.3
  • 4
    • 20044386942 scopus 로고    scopus 로고
    • The Alzheimer disease-related calcium-binding protein Calmyrin is present in human forebrain with an altered distribution in Alzheimer's as compared to normal ageing brains
    • doi: 10.1111/j.1365-2990.2005.00646.x
    • Bernstein, H. G., Blazejczyk, M., Rudka, T., Gundelfinger, E. D., Dobrowolny, H., Bogerts, B., et al. (2005). The Alzheimer disease-related calcium-binding protein Calmyrin is present in human forebrain with an altered distribution in Alzheimer's as compared to normal ageing brains. Neuropathol. Appl. Neurobiol. 31, 314-324. doi: 10.1111/j.1365-2990.2005.00646.x
    • (2005) Neuropathol. Appl. Neurobiol , vol.31 , pp. 314-324
    • Bernstein, H.G.1    Blazejczyk, M.2    Rudka, T.3    Gundelfinger, E.D.4    Dobrowolny, H.5    Bogerts, B.6
  • 5
    • 84859313330 scopus 로고    scopus 로고
    • Calcium signalling remodelling and disease
    • doi: 10.1042/BST20110766
    • Berridge, M. J. (2012). Calcium signalling remodelling and disease. Biochem. Soc. Trans. 40, 297-309. doi: 10.1042/BST20110766
    • (2012) Biochem. Soc. Trans , vol.40 , pp. 297-309
    • Berridge, M.J.1
  • 6
    • 0038125598 scopus 로고    scopus 로고
    • Calcium signalling: Dynamics, homeostasis and remodelling
    • doi: 10.1038/nrm1155
    • Berridge, M. J., Bootman, M. D., and Roderick, H. L. (2003). Calcium signalling: dynamics, homeostasis and remodelling. Nat. Rev. Mol. Cell Biol. 4, 517-529. doi: 10.1038/nrm1155
    • (2003) Nat. Rev. Mol. Cell Biol , vol.4 , pp. 517-529
    • Berridge, M.J.1    Bootman, M.D.2    Roderick, H.L.3
  • 7
    • 4444302167 scopus 로고    scopus 로고
    • Deranged neuronal calcium signaling and Huntington disease
    • doi: 10.1016/j.bbrc.2004.08.035
    • Bezprozvanny, I., and Hayden, M. R. (2004). Deranged neuronal calcium signaling and Huntington disease. Biochem. Biophys. Res. Commun. 322, 1310-1317. doi: 10.1016/j.bbrc.2004.08.035
    • (2004) Biochem. Biophys. Res. Commun , vol.322 , pp. 1310-1317
    • Bezprozvanny, I.1    Hayden, M.R.2
  • 8
    • 84888353917 scopus 로고    scopus 로고
    • Calcium signaling and neurodegeneration
    • Bezprozvanny, I. B. (2010). Calcium signaling and neurodegeneration. Acta Nat. 2, 72-82.
    • (2010) Acta Nat , vol.2 , pp. 72-82
    • Bezprozvanny, I.B.1
  • 9
    • 0032918399 scopus 로고    scopus 로고
    • Calretinin-sensor or buffer-function still unclear
    • Billing-Marczak, K., and Kuznicki, J. (1999). Calretinin-sensor or buffer-function still unclear. Pol. J. Pharmacol. 51, 173-178.
    • (1999) Pol. J. Pharmacol , vol.51 , pp. 173-178
    • Billing-Marczak, K.1    Kuznicki, J.2
  • 10
    • 67349193181 scopus 로고    scopus 로고
    • Biochemical characterization and expression analysis of a novel EF-hand Ca2+ binding protein calmyrin2 (Cib2) in brain indicates its function in NMDA receptor mediated Ca2+ signaling
    • doi: 10.1016/j.abb.2009.05.002
    • Blazejczyk, M., Sobczak, A., Debowska, K., Wisniewska, M. B., Kirilenko, A., Pikula, S., et al. (2009). Biochemical characterization and expression analysis of a novel EF-hand Ca2+ binding protein calmyrin2 (Cib2) in brain indicates its function in NMDA receptor mediated Ca2+ signaling. Arch. Biochem. Biophys. 487, 66-78. doi: 10.1016/j.abb.2009.05.002
    • (2009) Arch. Biochem. Biophys , vol.487 , pp. 66-78
    • Blazejczyk, M.1    Sobczak, A.2    Debowska, K.3    Wisniewska, M.B.4    Kirilenko, A.5    Pikula, S.6
  • 11
    • 29644434488 scopus 로고    scopus 로고
    • Ca2+-independent binding and cellular expression profiles question a significant role of calmyrin in transduction of Ca2+-signals to Alzheimer's disease-related presenilin 2 in forebrain
    • doi: 10.1016/j.bbadis.2005.09.006
    • Blazejczyk, M., Wojda, U., Sobczak, A., Spilker, C., Bernstein, H. G., Gundelfinger, E. D., et al. (2006). Ca2+-independent binding and cellular expression profiles question a significant role of calmyrin in transduction of Ca2+-signals to Alzheimer's disease-related presenilin 2 in forebrain. Biochim. Biophys. Acta 1762, 66-72. doi: 10.1016/j.bbadis.2005.09.006
    • (2006) Biochim. Biophys. Acta , vol.1762 , pp. 66-72
    • Blazejczyk, M.1    Wojda, U.2    Sobczak, A.3    Spilker, C.4    Bernstein, H.G.5    Gundelfinger, E.D.6
  • 12
    • 0034256090 scopus 로고    scopus 로고
    • Calmodulin: A prototypical calcium sensor
    • doi: 10.1016/S0962-8924(00)01800-6
    • Chin, D., and Means, A. R. (2000). Calmodulin: a prototypical calcium sensor. Trends Cell Biol. 10, 322-328. doi: 10.1016/S0962-8924(00)01800-6
    • (2000) Trends Cell Biol , vol.10 , pp. 322-328
    • Chin, D.1    Means, A.R.2
  • 13
    • 0029839623 scopus 로고    scopus 로고
    • Striatal interneurons in Huntington's disease: Selective increase in the density of calretinin-immunoreactive medium-sized neurons
    • doi: 10.1002/mds.870110605
    • Cicchetti, F., and Parent, A. (1996). Striatal interneurons in Huntington's disease: selective increase in the density of calretinin-immunoreactive medium-sized neurons. Mov. Disord. 11, 619-626. doi: 10.1002/mds.870110605
    • (1996) Mov. Disord , vol.11 , pp. 619-626
    • Cicchetti, F.1    Parent, A.2
  • 14
    • 23644455157 scopus 로고    scopus 로고
    • Mutant huntingtin represses CBP, but not p300, by binding and protein degradation
    • doi: 10.1016/j.mcn.2005.05.003
    • Cong, S. Y., Pepers, B. A., Evert, B. O., Rubinsztein, D. C., Roos, R. A., van Ommen, G. J., et al. (2005). Mutant huntingtin represses CBP, but not p300, by binding and protein degradation. Mol. Cell. Neurosci. 30, 560-571. doi: 10.1016/j.mcn.2005.05.003
    • (2005) Mol. Cell. Neurosci , vol.30 , pp. 560-571
    • Cong, S.Y.1    Pepers, B.A.2    Evert, B.O.3    Rubinsztein, D.C.4    Roos, R.A.5    van Ommen, G.J.6
  • 15
    • 33645109019 scopus 로고    scopus 로고
    • Selective deficits in the expression of striatalenriched mRNAs in Huntington's disease
    • doi: 10.1111/j.1471-4159.2005.03588.x
    • Desplats, P. A., Kass, K. E., Gilmartin, T., Stanwood, G. D., Woodward, E. L., Head, S. R., et al. (2006). Selective deficits in the expression of striatalenriched mRNAs in Huntington's disease. J. Neurochem. 96, 743-757. doi: 10.1111/j.1471-4159.2005.03588.x
    • (2006) J. Neurochem , vol.96 , pp. 743-757
    • Desplats, P.A.1    Kass, K.E.2    Gilmartin, T.3    Stanwood, G.D.4    Woodward, E.L.5    Head, S.R.6
  • 16
    • 84867337665 scopus 로고    scopus 로고
    • Calretinin interacts with huntingtin and reduces mutant huntingtincaused cytotoxicity
    • doi: 10.1111/j.14714159.2012.07919.x
    • Dong, G., Gross, K., Qiao, F., Ferguson, J., Callegari, E. A., Rezvani, K., et al. (2012). Calretinin interacts with huntingtin and reduces mutant huntingtincaused cytotoxicity. J. Neurochem. 123, 437-446. doi: 10.1111/j.14714159.2012.07919.x
    • (2012) J. Neurochem , vol.123 , pp. 437-446
    • Dong, G.1    Gross, K.2    Qiao, F.3    Ferguson, J.4    Callegari, E.A.5    Rezvani, K.6
  • 17
    • 0037047290 scopus 로고    scopus 로고
    • CacyBP/SIP, a calcyclin and Siah-1-interacting protein, binds EF-hand proteins of the S100 family
    • doi: 10.1074/jbc.M203602200
    • Filipek, A., Jastrzebska, B., Nowotny, M., and Kuznicki, J. (2002). CacyBP/SIP, a calcyclin and Siah-1-interacting protein, binds EF-hand proteins of the S100 family. J. Biol. Chem. 277, 28848-28852. doi: 10.1074/jbc.M203602200
    • (2002) J. Biol. Chem , vol.277 , pp. 28848-28852
    • Filipek, A.1    Jastrzebska, B.2    Nowotny, M.3    Kuznicki, J.4
  • 18
    • 2642703410 scopus 로고    scopus 로고
    • Molecular cloning and expression of a mouse brain cDNA encoding a novel protein target of calcyclin
    • doi: 10.1046/j.1471-4159.1998.70051793.x
    • Filipek, A., and Kuznicki, J. (1998). Molecular cloning and expression of a mouse brain cDNA encoding a novel protein target of calcyclin. J. Neurochem. 70, 1793-1798. doi: 10.1046/j.1471-4159.1998.70051793.x
    • (1998) J. Neurochem , vol.70 , pp. 1793-1798
    • Filipek, A.1    Kuznicki, J.2
  • 19
    • 50649103495 scopus 로고    scopus 로고
    • Age-dependent changes in neuronal distribution of CacyBP/SIP: Comparison to tubulin and the tau protein
    • doi: 10.1007/s00702-008-0062-3
    • Filipek, A., Schneider, G., Mietelska, A., Figiel, I., and Niewiadomska, G. (2008). Age-dependent changes in neuronal distribution of CacyBP/SIP: comparison to tubulin and the tau protein. J. Neural Transm. 115, 1257-1264. doi: 10.1007/s00702-008-0062-3
    • (2008) J. Neural Transm , vol.115 , pp. 1257-1264
    • Filipek, A.1    Schneider, G.2    Mietelska, A.3    Figiel, I.4    Niewiadomska, G.5
  • 20
    • 34248584090 scopus 로고    scopus 로고
    • Inositol trisphosphate receptor Ca2+ release channels
    • doi: 10.1152/physrev.00035.2006
    • Foskett, J. K., White, C., Cheung, K. H., and Mak, D. O. (2007). Inositol trisphosphate receptor Ca2+ release channels. Physiol. Rev. 87, 593-658. doi: 10.1152/physrev.00035.2006
    • (2007) Physiol. Rev , vol.87 , pp. 593-658
    • Foskett, J.K.1    White, C.2    Cheung, K.H.3    Mak, D.O.4
  • 21
    • 18444417998 scopus 로고    scopus 로고
    • Aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation
    • doi: 10.1016/S1534-5807(02)00189-2
    • Francis, R., McGrath, G., Zhang, J., Ruddy, D. A., Sym, M., Apfeld, J., et al. (2002). aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation. Dev. Cell 3, 85-97. doi: 10.1016/S1534-5807(02)00189-2
    • (2002) Dev. Cell , vol.3 , pp. 85-97
    • Francis, R.1    McGrath, G.2    Zhang, J.3    Ruddy, D.A.4    Sym, M.5    Apfeld, J.6
  • 23
    • 79959506785 scopus 로고    scopus 로고
    • Huntington's disease, calcium, and mitochondria
    • doi: 10.1002/biof.162
    • Giacomello, M., Hudec, R., and Lopreiato, R. (2011). Huntington's disease, calcium, and mitochondria. Biofactors 37, 206-218. doi: 10.1002/biof.162
    • (2011) Biofactors , vol.37 , pp. 206-218
    • Giacomello, M.1    Hudec, R.2    Lopreiato, R.3
  • 24
    • 84874612390 scopus 로고    scopus 로고
    • Neuronal Ca(2+) dyshomeostasis in Huntington disease
    • doi: 10.4161/pri.23581
    • Giacomello, M., Oliveros, J. C., Naranjo, J. R., and Carafoli, E. (2013). Neuronal Ca(2+) dyshomeostasis in Huntington disease. Prion 7, 76-84. doi: 10.4161/pri.23581
    • (2013) Prion , vol.7 , pp. 76-84
    • Giacomello, M.1    Oliveros, J.C.2    Naranjo, J.R.3    Carafoli, E.4
  • 25
    • 0037154158 scopus 로고    scopus 로고
    • APH-1 is a multipass membrane protein essential for the Notch signaling pathway in Caenorhabditis elegans embryos
    • doi: 10.1073/pnas.022523499
    • Goutte, C., Tsunozaki, M., Hale, V. A., and Priess, J. R. (2002). APH-1 is a multipass membrane protein essential for the Notch signaling pathway in Caenorhabditis elegans embryos. Proc. Natl. Acad. Sci. U.S.A. 99, 775-779. doi: 10.1073/pnas.022523499
    • (2002) Proc. Natl. Acad. Sci. U.S.A , vol.99 , pp. 775-779
    • Goutte, C.1    Tsunozaki, M.2    Hale, V.A.3    Priess, J.R.4
  • 26
    • 4344699902 scopus 로고    scopus 로고
    • Calreticulin, Ca2+, and calcineurin signaling from the endoplasmic reticulum
    • Groenendyk, J., Lynch, J., and Michalak, M. (2004). Calreticulin, Ca2+, and calcineurin signaling from the endoplasmic reticulum. Mol. Cells 17, 383-389.
    • (2004) Mol. Cells , vol.17 , pp. 383-389
    • Groenendyk, J.1    Lynch, J.2    Michalak, M.3
  • 27
    • 84883739485 scopus 로고    scopus 로고
    • Native STIM2 and ORAI1 proteins form a calcium-sensitive and thapsigargin-insensitive complex in cortical neurons
    • doi: 10.1111/jnc.12320
    • Gruszczynska-Biegala, J., and Kuznicki, J. (2013). Native STIM2 and ORAI1 proteins form a calcium-sensitive and thapsigargin-insensitive complex in cortical neurons. J. Neurochem. 126, 727-738. doi: 10.1111/jnc.12320
    • (2013) J. Neurochem , vol.126 , pp. 727-738
    • Gruszczynska-Biegala, J.1    Kuznicki, J.2
  • 28
    • 79955589964 scopus 로고    scopus 로고
    • Differential roles for STIM1 and STIM2 in store-operated calcium entry in rat neurons
    • doi: 10.1371/journal.pone.0019285
    • Gruszczynska-Biegala, J., Pomorski, P., Wisniewska, M. B., and Kuznicki, J. (2011). Differential roles for STIM1 and STIM2 in store-operated calcium entry in rat neurons. PLoS ONE 6:e19285. doi: 10.1371/journal.pone.0019285
    • (2011) PLoS ONE , vol.6
    • Gruszczynska-Biegala, J.1    Pomorski, P.2    Wisniewska, M.B.3    Kuznicki, J.4
  • 29
    • 24644455527 scopus 로고    scopus 로고
    • Ryanodine receptors
    • doi: 10.1016/j.ceca.2005.06.037
    • Hamilton, S. L. (2005). Ryanodine receptors. Cell Calcium 38, 253-260. doi: 10.1016/j.ceca.2005.06.037
    • (2005) Cell Calcium , vol.38 , pp. 253-260
    • Hamilton, S.L.1
  • 30
    • 84875692443 scopus 로고    scopus 로고
    • The plasma membrane channel ORAI1 mediates detrimental calcium influx caused by endogenous oxidative stress
    • doi: 10.1038/cddis.2012.216
    • Henke, N., Albrecht, P., Bouchachia, I., Ryazantseva, M., Knoll, K., Lewerenz, J., et al. (2013). The plasma membrane channel ORAI1 mediates detrimental calcium influx caused by endogenous oxidative stress. Cell Death Dis. 4:e470. doi: 10.1038/cddis.2012.216
    • (2013) Cell Death Dis , vol.4
    • Henke, N.1    Albrecht, P.2    Bouchachia, I.3    Ryazantseva, M.4    Knoll, K.5    Lewerenz, J.6
  • 31
    • 84871311580 scopus 로고    scopus 로고
    • Stromal interaction molecule 1 (STIM1) is involved in the regulation of mitochondrial shape and bioenergetics and plays a role in oxidative stress
    • doi: 10.1074/jbc.M112.417212
    • Henke, N., Albrecht, P., Pfeiffer, A., Toutzaris, D., Zanger, K., and Methner, A. (2012). Stromal interaction molecule 1 (STIM1) is involved in the regulation of mitochondrial shape and bioenergetics and plays a role in oxidative stress. J. Biol. Chem. 287, 42042-42052. doi: 10.1074/jbc.M112.417212
    • (2012) J. Biol. Chem , vol.287 , pp. 42042-42052
    • Henke, N.1    Albrecht, P.2    Pfeiffer, A.3    Toutzaris, D.4    Zanger, K.5    Methner, A.6
  • 32
    • 33644783812 scopus 로고    scopus 로고
    • Regional and cellular gene expression changes in human Huntington's disease brain
    • doi: 10.1093/hmg/ddl013
    • Hodges, A., Strand, A. D., Aragaki, A. K., Kuhn, A., Sengstag, T., Hughes, G., et al. (2006). Regional and cellular gene expression changes in human Huntington's disease brain. Hum. Mol. Genet. 15, 965-977. doi: 10.1093/hmg/ddl013
    • (2006) Hum. Mol. Genet , vol.15 , pp. 965-977
    • Hodges, A.1    Strand, A.D.2    Aragaki, A.K.3    Kuhn, A.4    Sengstag, T.5    Hughes, G.6
  • 33
    • 0030610240 scopus 로고    scopus 로고
    • Attenuation of Gi- and Gq-mediated signaling by expression of RGS4 or GAIP in mammalian cells
    • doi: 10.1073/pnas.94.12.6159
    • Huang, C., Hepler, J. R., Gilman, A. G., and Mumby, S. M. (1997). Attenuation of Gi- and Gq-mediated signaling by expression of RGS4 or GAIP in mammalian cells. Proc. Natl. Acad. Sci. U.S.A. 94, 6159-6163. doi: 10.1073/pnas.94.12.6159
    • (1997) Proc. Natl. Acad. Sci. U.S.A , vol.94 , pp. 6159-6163
    • Huang, C.1    Hepler, J.R.2    Gilman, A.G.3    Mumby, S.M.4
  • 34
    • 33748136477 scopus 로고    scopus 로고
    • STIM1 carboxyl-terminus activates native SOC, I(crac) and TRPC1 channels
    • doi: 10.1038/ncb1454
    • Huang, G. N., Zeng, W., Kim, J. Y., Yuan, J. P., Han, L., Muallem, S., et al. (2006). STIM1 carboxyl-terminus activates native SOC, I(crac) and TRPC1 channels. Nat. Cell Biol. 8, 1003-1010. doi: 10.1038/ncb1454
    • (2006) Nat. Cell Biol , vol.8 , pp. 1003-1010
    • Huang, G.N.1    Zeng, W.2    Kim, J.Y.3    Yuan, J.P.4    Han, L.5    Muallem, S.6
  • 35
    • 84878243748 scopus 로고    scopus 로고
    • Analysis of calcium homeostasis in fresh lymphocytes from patients with sporadic Alzheimer's disease or mild cognitive impairment
    • doi: 10.1016/j.bbamcr.2013.01.012
    • Jaworska, A., Dzbek, J., Styczynska, M., and Kuznicki, J. (2013). Analysis of calcium homeostasis in fresh lymphocytes from patients with sporadic Alzheimer's disease or mild cognitive impairment. Biochim. Biophys. Acta 1833, 1692-1699. doi: 10.1016/j.bbamcr.2013.01.012
    • (2013) Biochim. Biophys. Acta , vol.1833 , pp. 1692-1699
    • Jaworska, A.1    Dzbek, J.2    Styczynska, M.3    Kuznicki, J.4
  • 37
    • 59049093840 scopus 로고    scopus 로고
    • Expression of STIM1 in brain and puncta-like co-localization of STIM1 and ORAI1 upon depletion of Ca(2+) store in neurons
    • doi: 10.1016/j.neuint.2008.10.005
    • Klejman, M. E., Gruszczynska-Biegala, J., Skibinska-Kijek, A., Wisniewska, M. B., Misztal, K., Blazejczyk, M., et al. (2009). Expression of STIM1 in brain and puncta-like co-localization of STIM1 and ORAI1 upon depletion of Ca(2+) store in neurons. Neurochem. Int. 54, 49-55. doi: 10.1016/j.neuint.2008.10.005
    • (2009) Neurochem. Int , vol.54 , pp. 49-55
    • Klejman, M.E.1    Gruszczynska-Biegala, J.2    Skibinska-Kijek, A.3    Wisniewska, M.B.4    Misztal, K.5    Blazejczyk, M.6
  • 38
    • 10744223903 scopus 로고    scopus 로고
    • A conserved GXXXG motif in APH-1 is critical for assembly and activity of the gammasecretase complex
    • doi: 10.1074/jbc.M309745200
    • Lee, S. F., Shah, S., Yu, C., Wigley, W. C., Li, H., Lim, M., et al. (2004). A conserved GXXXG motif in APH-1 is critical for assembly and activity of the gammasecretase complex. J. Biol. Chem. 279, 4144-4152. doi: 10.1074/jbc.M309745200
    • (2004) J. Biol. Chem , vol.279 , pp. 4144-4152
    • Lee, S.F.1    Shah, S.2    Yu, C.3    Wigley, W.C.4    Li, H.5    Lim, M.6
  • 39
    • 0034657414 scopus 로고    scopus 로고
    • Capacitative calcium entry deficits and elevated luminal calcium content in mutant presenilin-1 knockin mice
    • doi: 10.1083/jcb.149.4.793
    • Leissring, M. A., Akbari, Y., Fanger, C. M., Cahalan, M. D., Mattson, M. P., and LaFerla, F. M. (2000). Capacitative calcium entry deficits and elevated luminal calcium content in mutant presenilin-1 knockin mice. J. Cell Biol. 149, 793-798. doi: 10.1083/jcb.149.4.793
    • (2000) J. Cell Biol , vol.149 , pp. 793-798
    • Leissring, M.A.1    Akbari, Y.2    Fanger, C.M.3    Cahalan, M.D.4    Mattson, M.P.5    Laferla, F.M.6
  • 40
    • 0032563107 scopus 로고    scopus 로고
    • A human HAP1 homologue. Cloning, expression, and interaction with huntingtin
    • doi: 10.1074/jbc.273.30.19220
    • Li, S. H., Hosseini, S. H., Gutekunst, C. A., Hersch, S. M., Ferrante, R. J., and Li, X. J. (1998). A human HAP1 homologue. Cloning, expression, and interaction with huntingtin. J. Biol. Chem. 273, 19220-19227. doi: 10.1074/jbc.273.30.19220
    • (1998) J. Biol. Chem , vol.273 , pp. 19220-19227
    • Li, S.H.1    Hosseini, S.H.2    Gutekunst, C.A.3    Hersch, S.M.4    Ferrante, R.J.5    Li, X.J.6
  • 41
    • 1242338856 scopus 로고    scopus 로고
    • Huntingtin-protein interactions and the pathogenesis of Huntington's disease
    • doi: 10.1016/j.tig.2004.01.008
    • Li, S. H., and Li, X. J. (2004). Huntingtin-protein interactions and the pathogenesis of Huntington's disease. Trends Genet. 20, 146-154. doi: 10.1016/j.tig.2004.01.008
    • (2004) Trends Genet , vol.20 , pp. 146-154
    • Li, S.H.1    Li, X.J.2
  • 42
    • 0028803757 scopus 로고
    • A huntingtin-associated protein enriched in brain with implications for pathology
    • doi: 10.1038/378398a0
    • Li, X. J., Li, S. H., Sharp, A. H., Nucifora, F. C. Jr., Schilling, G., et al. (1995). A huntingtin-associated protein enriched in brain with implications for pathology. Nature 378, 398-402. doi: 10.1038/378398a0
    • (1995) Nature , vol.378 , pp. 398-402
    • Li, X.J.1    Li, S.H.2    Sharp, A.H.3    Nucifora Jr., F.C.4    Schilling, G.5
  • 43
    • 21844432686 scopus 로고    scopus 로고
    • STIM is a Ca2+ sensor essential for Ca2+-store-depletiontriggered Ca2+ influx
    • doi: 10.1016/j.cub.2005.05.055
    • Liou, J., Kim, M. L., Heo, W. D., Jones, J. T., Myers, J. W., Ferrell, J. E., et al. (2005). STIM is a Ca2+ sensor essential for Ca2+-store-depletiontriggered Ca2+ influx. Curr. Biol. 15, 1235-1241. doi: 10.1016/j.cub.2005.05.055
    • (2005) Curr. Biol , vol.15 , pp. 1235-1241
    • Liou, J.1    Kim, M.L.2    Heo, W.D.3    Jones, J.T.4    Myers, J.W.5    Ferrell, J.E.6
  • 44
    • 0037424275 scopus 로고    scopus 로고
    • PEN-2 and APH-1 coordinately regulate proteolytic processing of presenilin 1
    • doi: 10.1074/jbc.C200648200
    • Luo, W. J., Wang, H., Li, H., Kim, B. S., Shah, S., Lee, H. J., et al. (2003). PEN-2 and APH-1 coordinately regulate proteolytic processing of presenilin 1. J. Biol. Chem. 278, 7850-7854. doi: 10.1074/jbc.C200648200
    • (2003) J. Biol. Chem , vol.278 , pp. 7850-7854
    • Luo, W.J.1    Wang, H.2    Li, H.3    Kim, B.S.4    Shah, S.5    Lee, H.J.6
  • 45
    • 0037101835 scopus 로고    scopus 로고
    • Dysregulation of gene expression in the R6/2 model of polyglutamine disease: Parallel changes in muscle and brain
    • doi: 10.1093/hmg/11.17.1911
    • Luthi-Carter, R., Hanson, S. A., Strand, A. D., Bergstrom, D. A., Chun, W., Peters, N. L., et al. (2002a). Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain. Hum. Mol. Genet. 11, 1911-1926. doi: 10.1093/hmg/11.17.1911
    • (2002) Hum. Mol. Genet , vol.11 , pp. 1911-1926
    • Luthi-Carter, R.1    Hanson, S.A.2    Strand, A.D.3    Bergstrom, D.A.4    Chun, W.5    Peters, N.L.6
  • 46
    • 0037101837 scopus 로고    scopus 로고
    • Polyglutamine and transcription: Gene expression changes shared by DRPLA and Huntington's disease mouse models reveal context-independent effects
    • doi: 10.1093/hmg/11.17.1927
    • Luthi-Carter, R., Strand, A. D., Hanson, S. A., Kooperberg, C., Schilling, G., La Spada, A. R., et al. (2002b). Polyglutamine and transcription: gene expression changes shared by DRPLA and Huntington's disease mouse models reveal context-independent effects. Hum. Mol. Genet. 11, 1927-1937. doi: 10.1093/hmg/11.17.1927
    • (2002) Hum. Mol. Genet , vol.11 , pp. 1927-1937
    • Luthi-Carter, R.1    Strand, A.D.2    Hanson, S.A.3    Kooperberg, C.4    Schilling, G.5    la Spada, A.R.6
  • 47
    • 0034702030 scopus 로고    scopus 로고
    • Decreased expression of striatal signaling genes in a mouse model of Huntington's disease
    • doi: 10.1093/hmg/9.9.1259
    • Luthi-Carter, R., Strand, A., Peters, N. L., Solano, S. M., Hollingsworth, Z. R., Menon, A. S., et al. (2000). Decreased expression of striatal signaling genes in a mouse model of Huntington's disease. Hum. Mol. Genet. 9, 1259-1271. doi: 10.1093/hmg/9.9.1259
    • (2000) Hum. Mol. Genet , vol.9 , pp. 1259-1271
    • Luthi-Carter, R.1    Strand, A.2    Peters, N.L.3    Solano, S.M.4    Hollingsworth, Z.R.5    Menon, A.S.6
  • 48
    • 16044373842 scopus 로고    scopus 로고
    • Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
    • doi: 10.1016/S0092-8674(00)81369-0
    • Mangiarini, L., Sathasivam, K., Seller, M., Cozens, B., Harper, A., Hetherington, C., et al. (1996). Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice. Cell 87, 493-506. doi: 10.1016/S0092-8674(00)81369-0
    • (1996) Cell , vol.87 , pp. 493-506
    • Mangiarini, L.1    Sathasivam, K.2    Seller, M.3    Cozens, B.4    Harper, A.5    Hetherington, C.6
  • 49
    • 55849096212 scopus 로고    scopus 로고
    • The fate of the large striatal interneurons expressing calretinin in Huntington's disease
    • doi: 10.1016/j.neures.2008.08.007
    • Massouh, M., Wallman, M. J., Pourcher, E., and Parent, A. (2008). The fate of the large striatal interneurons expressing calretinin in Huntington's disease. Neurosci. Res. 62, 216-224. doi: 10.1016/j.neures.2008.08.007
    • (2008) Neurosci. Res , vol.62 , pp. 216-224
    • Massouh, M.1    Wallman, M.J.2    Pourcher, E.3    Parent, A.4
  • 50
    • 0035947080 scopus 로고    scopus 로고
    • Siah-1, SIP, and Ebi collaborate in a novel pathway for beta-catenin degradation linked to p53 responses
    • doi: 10.1016/S1097-2765(01)00242-8
    • Matsuzawa, S. I., and Reed, J. C. (2001). Siah-1, SIP, and Ebi collaborate in a novel pathway for beta-catenin degradation linked to p53 responses. Mol. Cell 7, 915-926. doi: 10.1016/S1097-2765(01)00242-8
    • (2001) Mol. Cell , vol.7 , pp. 915-926
    • Matsuzawa, S.I.1    Reed, J.C.2
  • 51
    • 59849120392 scopus 로고    scopus 로고
    • Calreticulin, a multi-process calcium-buffering chaperone of the endoplasmic reticulum
    • doi: 10.1042/BJ20081847
    • Michalak, M., Groenendyk, J., Szabo, E., Gold, L. I., and Opas, M. (2009). Calreticulin, a multi-process calcium-buffering chaperone of the endoplasmic reticulum. Biochem. J. 417, 651-666. doi: 10.1042/BJ20081847
    • (2009) Biochem. J , vol.417 , pp. 651-666
    • Michalak, M.1    Groenendyk, J.2    Szabo, E.3    Gold, L.I.4    Opas, M.5
  • 52
    • 47849122005 scopus 로고    scopus 로고
    • Huntingtin interacting protein 1 can regulate neurogenesis in Drosophila
    • doi: 10.1111/j.1460-9568.2008.06359.x
    • Moores, J. N., Roy, S., Nicholson, D. W., and Staveley, B. E. (2008). Huntingtin interacting protein 1 can regulate neurogenesis in Drosophila. Eur. J. Neurosci. 28, 599-609. doi: 10.1111/j.1460-9568.2008.06359.x
    • (2008) Eur. J. Neurosci , vol.28 , pp. 599-609
    • Moores, J.N.1    Roy, S.2    Nicholson, D.W.3    Staveley, B.E.4
  • 53
    • 79957809118 scopus 로고    scopus 로고
    • Dendritic EGFP-STIM1 activation after type I metabotropic glutamate and muscarinic acetylcholine receptor stimulation in hippocampal neuron
    • doi: 10.1002/jnr.22648
    • Ng, A. N., Krogh, M., and Toresson, H. (2011). Dendritic EGFP-STIM1 activation after type I metabotropic glutamate and muscarinic acetylcholine receptor stimulation in hippocampal neuron. J. Neurosci. Res. 89, 1235-1244. doi: 10.1002/jnr.22648
    • (2011) J. Neurosci. Res , vol.89 , pp. 1235-1244
    • Ng, A.N.1    Krogh, M.2    Toresson, H.3
  • 54
    • 84876145821 scopus 로고    scopus 로고
    • Calcium homeostasis in aging neurons
    • doi: 10.3389/fgene.2012.00200
    • Nikoletopoulou, V., and Tavernarakis, N. (2012). Calcium homeostasis in aging neurons. Front. Genet. 3:200. doi: 10.3389/fgene.2012.00200
    • (2012) Front. Genet , vol.3 , pp. 200
    • Nikoletopoulou, V.1    Tavernarakis, N.2
  • 55
    • 71849096141 scopus 로고    scopus 로고
    • How does multiple testing correction work?
    • doi: 10.1038/nbt1209-1135
    • Noble, W. S. (2009). How does multiple testing correction work? Nat. Biotechnol. 27, 1135-1137. doi: 10.1038/nbt1209-1135
    • (2009) Nat. Biotechnol , vol.27 , pp. 1135-1137
    • Noble, W.S.1
  • 56
    • 77957332175 scopus 로고    scopus 로고
    • The CRAC channel activator STIM1 binds and inhibits L-type voltage-gated calcium channels
    • doi: 10.1126/science.1191027
    • Park, C. Y., Shcheglovitov, A., and Dolmetsch, R. (2010). The CRAC channel activator STIM1 binds and inhibits L-type voltage-gated calcium channels. Science 330, 101-105. doi: 10.1126/science.1191027
    • (2010) Science , vol.330 , pp. 101-105
    • Park, C.Y.1    Shcheglovitov, A.2    Dolmetsch, R.3
  • 58
    • 66049132843 scopus 로고    scopus 로고
    • The ER and ageing II: Calcium homeostasis
    • doi: 10.1016/j.arr.2009.05.002
    • Puzianowska-Kuznicka, M., and Kuznicki, J. (2009). The ER and ageing II: calcium homeostasis. Ageing Res. Rev. 8, 160-172. doi: 10.1016/j.arr.2009.05.002
    • (2009) Ageing Res. Rev , vol.8 , pp. 160-172
    • Puzianowska-Kuznicka, M.1    Kuznicki, J.2
  • 59
    • 74849091009 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor-mediated cell signaling pathways are altered in a mouse model of Huntington's disease
    • doi: 10.1523/JNEUROSCI.4974-09.2010
    • Ribeiro, F. M., Paquet, M., Ferreira, L. T., Cregan, T., Swan, P., Cregan, S. P., et al. (2010). Metabotropic glutamate receptor-mediated cell signaling pathways are altered in a mouse model of Huntington's disease. J. Neurosci. 30, 316-324. doi: 10.1523/JNEUROSCI.4974-09.2010
    • (2010) J. Neurosci , vol.30 , pp. 316-324
    • Ribeiro, F.M.1    Paquet, M.2    Ferreira, L.T.3    Cregan, T.4    Swan, P.5    Cregan, S.P.6
  • 60
    • 33846540080 scopus 로고    scopus 로고
    • The first 17 amino acids of Huntingtin modulate its sub-cellular localization, aggregation and effects on calcium homeostasis
    • doi: 10.1093/hmg/ ddl440
    • Rockabrand, E., Slepko, N., Pantalone, A., Nukala, V. N., Kazantsev, A., Marsh, J. L., et al. (2007). The first 17 amino acids of Huntingtin modulate its sub-cellular localization, aggregation and effects on calcium homeostasis. Hum. Mol. Genet. 16, 61-77. doi: 10.1093/hmg/ ddl440
    • (2007) Hum. Mol. Genet , vol.16 , pp. 61-77
    • Rockabrand, E.1    Slepko, N.2    Pantalone, A.3    Nukala, V.N.4    Kazantsev, A.5    Marsh, J.L.6
  • 61
    • 21044439334 scopus 로고    scopus 로고
    • STIM1, an essential and conserved component of store-operated Ca2+ channel function
    • doi: 10.1083/jcb.2005 02019
    • Roos, J., DiGregorio, P. J., Yeromin, A. V., Ohlsen, K., Lioudyno, M., Zhang, S., et al. (2005). STIM1, an essential and conserved component of store-operated Ca2+ channel function. J. Cell Biol. 169, 435-445. doi: 10.1083/jcb.2005 02019
    • (2005) J. Cell Biol , vol.169 , pp. 435-445
    • Roos, J.1    Digregorio, P.J.2    Yeromin, A.V.3    Ohlsen, K.4    Lioudyno, M.5    Zhang, S.6
  • 62
    • 84878604404 scopus 로고    scopus 로고
    • Familial Alzheimer's disease-linked presenilin-1 mutation M146V affects store-operated calcium entry: Does gain look like loss?
    • doi: 10.1016/j.biochi.2013.04.009
    • Ryazantseva, M., Skobeleva, K., and Kaznacheyeva, E. (2013). Familial Alzheimer's disease-linked presenilin-1 mutation M146V affects store-operated calcium entry: does gain look like loss? Biochimie 95, 1506-1509. doi: 10.1016/j.biochi.2013.04.009
    • (2013) Biochimie , vol.95 , pp. 1506-1509
    • Ryazantseva, M.1    Skobeleva, K.2    Kaznacheyeva, E.3
  • 63
    • 0023914367 scopus 로고
    • Loss of matrix calcium-binding protein-containing neurons in Huntington's disease
    • doi: 10.1016/S0140-6736(88) 92073-9
    • Seto-Ohshima, A., Emson, P. C., Lawson, E., Mountjoy, C. Q., and Carrasco, L. H. (1988). Loss of matrix calcium-binding protein-containing neurons in Huntington's disease. Lancet 1, 1252-1255. doi: 10.1016/S0140-6736(88) 92073-9
    • (1988) Lancet , vol.1 , pp. 1252-1255
    • Seto-Ohshima, A.1    Emson, P.C.2    Lawson, E.3    Mountjoy, C.Q.4    Carrasco, L.H.5
  • 64
    • 84880509648 scopus 로고    scopus 로고
    • An siRNA screen for NFAT activation identifies septins as coordinators of store-operated Ca2+ entry
    • doi: 10.1038/nature12229
    • Sharma, S., Quintana, A., Findlay, G. M., Mettlen, M., Baust, B., Jain, M., et al. (2013). An siRNA screen for NFAT activation identifies septins as coordinators of store-operated Ca2+ entry. Nature 499, 238-242. doi: 10.1038/nature12229
    • (2013) Nature , vol.499 , pp. 238-242
    • Sharma, S.1    Quintana, A.2    Findlay, G.M.3    Mettlen, M.4    Baust, B.5    Jain, M.6
  • 66
    • 10744227174 scopus 로고    scopus 로고
    • Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease
    • doi: 10.1093/hmg/ddg169
    • Slow, E. J., van Raamsdonk, J., Rogers, D., Coleman, S. H., Graham, R. K., Deng, Y., et al. (2003). Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease. Hum. Mol. Genet. 12, 1555-1567. doi: 10.1093/hmg/ddg169
    • (2003) Hum. Mol. Genet , vol.12 , pp. 1555-1567
    • Slow, E.J.1    van Raamsdonk, J.2    Rogers, D.3    Coleman, S.H.4    Graham, R.K.5    Deng, Y.6
  • 67
    • 80055007992 scopus 로고    scopus 로고
    • Store-operated calcium entry modulates neuronal network activity in a model of chronic epilepsy
    • doi: 10.1016/j.expneurol.2011.08.022
    • Steinbeck, J. A., Henke, N., Opatz, J., Gruszczynska-Biegala, J., Schneider, L., Theiss, S., et al. (2011). Store-operated calcium entry modulates neuronal network activity in a model of chronic epilepsy. Exp. Neurol. 232, 185-194. doi: 10.1016/j.expneurol.2011.08.022
    • (2011) Exp. Neurol , vol.232 , pp. 185-194
    • Steinbeck, J.A.1    Henke, N.2    Opatz, J.3    Gruszczynska-Biegala, J.4    Schneider, L.5    Theiss, S.6
  • 68
    • 0037408279 scopus 로고    scopus 로고
    • Transcriptional abnormalities in Huntington disease
    • doi: 10.1016/S0168-9525(03)00074-X
    • Sugars, K. L., and Rubinsztein, D. C. (2003). Transcriptional abnormalities in Huntington disease. Trends Genet. 19, 233-238. doi: 10.1016/S0168-9525(03)00074-X
    • (2003) Trends Genet , vol.19 , pp. 233-238
    • Sugars, K.L.1    Rubinsztein, D.C.2
  • 69
    • 80052646443 scopus 로고    scopus 로고
    • Presenilins function in ER calcium leak and Alzheimer's disease pathogenesis
    • doi: 10.1016/j.ceca.2011.05.013
    • Supnet, C., and Bezprozvanny, I. (2011). Presenilins function in ER calcium leak and Alzheimer's disease pathogenesis. Cell Calcium 50, 303-309. doi: 10.1016/j.ceca.2011.05.013
    • (2011) Cell Calcium , vol.50 , pp. 303-309
    • Supnet, C.1    Bezprozvanny, I.2
  • 70
    • 14044264256 scopus 로고    scopus 로고
    • Disturbed Ca2+ signaling and apoptosis of medium spiny neurons in Huntington's disease
    • doi: 10.1073/pnas.0409402102
    • Tang, T. S., Slow, E., Lupu, V., Stavrovskaya, I. G., Sugimori, M., Llinas, R., et al. (2005). Disturbed Ca2+ signaling and apoptosis of medium spiny neurons in Huntington's disease. Proc. Natl. Acad. Sci. U.S.A. 102, 2602-2607. doi: 10.1073/pnas.0409402102
    • (2005) Proc. Natl. Acad. Sci. U.S.A , vol.102 , pp. 2602-2607
    • Tang, T.S.1    Slow, E.2    Lupu, V.3    Stavrovskaya, I.G.4    Sugimori, M.5    Llinas, R.6
  • 71
    • 0041963057 scopus 로고    scopus 로고
    • Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1
    • doi: 10.1016/S0896-6273(03)00366-0
    • Tang, T. S., Tu, H., Chan, E. Y., Maximov, A., Wang, Z., Wellington, C. L., et al. (2003). Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1. Neuron 39, 227-239. doi: 10.1016/S0896-6273(03)00366-0
    • (2003) Neuron , vol.39 , pp. 227-239
    • Tang, T.S.1    Tu, H.2    Chan, E.Y.3    Maximov, A.4    Wang, Z.5    Wellington, C.L.6
  • 72
    • 8144228679 scopus 로고    scopus 로고
    • HAP1 facilitates effects of mutant huntingtin on inositol 1,4,5-trisphosphate-induced Ca release in primary culture of striatal medium spiny neurons
    • doi: 10.1111/j.1460-9568.2004. 03633.x
    • Tang, T. S., Tu, H., Orban, P. C., Chan, E. Y., Hayden, M. R., and Bezprozvanny, I. (2004). HAP1 facilitates effects of mutant huntingtin on inositol 1,4,5-trisphosphate-induced Ca release in primary culture of striatal medium spiny neurons. Eur. J. Neurosci. 20, 1779-1787. doi: 10.1111/j.1460-9568.2004. 03633.x
    • (2004) Eur. J. Neurosci , vol.20 , pp. 1779-1787
    • Tang, T.S.1    Tu, H.2    Orban, P.C.3    Chan, E.Y.4    Hayden, M.R.5    Bezprozvanny, I.6
  • 73
    • 0242361780 scopus 로고    scopus 로고
    • Role of proteolysis in polyglutamine disorders
    • doi: 10.1002/jnr.10746
    • Tarlac, V., and Storey, E. (2003). Role of proteolysis in polyglutamine disorders. J. Neurosci. Res. 74, 406-416. doi: 10.1002/jnr.10746
    • (2003) J. Neurosci. Res , vol.74 , pp. 406-416
    • Tarlac, V.1    Storey, E.2
  • 74
    • 34248997850 scopus 로고    scopus 로고
    • The importance of being subtle: Small changes in calcium homeostasis control cognitive decline in normal aging
    • doi: 10.1111/j.1474-9726.2007.00296.x
    • Toescu, E. C., and Verkhratsky, A. (2007). The importance of being subtle: small changes in calcium homeostasis control cognitive decline in normal aging. Aging Cell 6, 267-273. doi: 10.1111/j.1474-9726.2007.00296.x
    • (2007) Aging Cell , vol.6 , pp. 267-273
    • Toescu, E.C.1    Verkhratsky, A.2
  • 75
    • 33847663446 scopus 로고    scopus 로고
    • Selective degeneration in YAC mouse models of Huntington disease
    • doi: 10.1016/j.brainresbull.2006.10.018
    • Van Raamsdonk, J. M., Warby, S. C., and Hayden, M. R. (2007). Selective degeneration in YAC mouse models of Huntington disease. Brain Res. Bull. 72, 124-131. doi: 10.1016/j.brainresbull.2006.10.018
    • (2007) Brain Res. Bull , vol.72 , pp. 124-131
    • van Raamsdonk, J.M.1    Warby, S.C.2    Hayden, M.R.3
  • 76
    • 57049133956 scopus 로고    scopus 로고
    • Mutant huntingtin activates Nrf2-responsive genes and impairs dopamine synthesis in a PC12 model of Huntington's disease
    • doi: 10.1186/1471-2199-9-84
    • van Roon-Mom, W. M., Pepers, B. A., t Hoen, P. A., Verwijmeren, C. A., den Dunnen, J. T., Dorsman, J. C., et al. (2008). Mutant huntingtin activates Nrf2-responsive genes and impairs dopamine synthesis in a PC12 model of Huntington's disease. BMC Mol. Biol. 9:84. doi: 10.1186/1471-2199-9-84
    • (2008) BMC Mol. Biol , vol.9 , pp. 84
    • van Roon-Mom, W.M.1    Pepers, B.A.2    T Hoen, P.A.3    Verwijmeren, C.A.4    den Dunnen, J.T.5    Dorsman, J.C.6
  • 77
    • 33744479684 scopus 로고    scopus 로고
    • CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry
    • doi: 10.1126/science.1127883
    • Vig, M., Peinelt, C., Beck, A., Koomoa, D. L., Rabah, D., Koblan-Huberson, M., et al. (2006). CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry. Science 312, 1220-1223. doi: 10.1126/science.1127883
    • (2006) Science , vol.312 , pp. 1220-1223
    • Vig, M.1    Peinelt, C.2    Beck, A.3    Koomoa, D.L.4    Rabah, D.5    Koblan-Huberson, M.6
  • 79
    • 0030059870 scopus 로고    scopus 로고
    • Antibody recognition of calcium-binding proteins depends on their calcium-binding status
    • doi: 10.1046/j.1471-4159.1996.66020764.x
    • Winsky, L., and Kuznicki, J. (1996). Antibody recognition of calcium-binding proteins depends on their calcium-binding status. J. Neurochem. 66, 764-771. doi: 10.1046/j.1471-4159.1996.66020764.x
    • (1996) J. Neurochem , vol.66 , pp. 764-771
    • Winsky, L.1    Kuznicki, J.2
  • 80
    • 56149105398 scopus 로고    scopus 로고
    • Calcium ions in neuronal degeneration
    • doi: 10.1002/iub.91
    • Wojda, U., Salinska, E., and Kuznicki, J. (2008). Calcium ions in neuronal degeneration. IUBMB Life 60, 575-590. doi: 10.1002/iub.91
    • (2008) IUBMB Life , vol.60 , pp. 575-590
    • Wojda, U.1    Salinska, E.2    Kuznicki, J.3
  • 81
    • 79959495111 scopus 로고    scopus 로고
    • Neuronal store-operated calcium entry pathway as a novel therapeutic target for Huntington's disease treatment
    • doi: 10.1016/j.chembiol.2011.04.012
    • Wu, J., Shih, H. P., Vigont, V., Hrdlicka, L., Diggins, L., Singh, C., et al. (2011). Neuronal store-operated calcium entry pathway as a novel therapeutic target for Huntington's disease treatment. Chem. Biol. 18, 777-793. doi: 10.1016/j.chembiol.2011.04.012
    • (2011) Chem. Biol , vol.18 , pp. 777-793
    • Wu, J.1    Shih, H.P.2    Vigont, V.3    Hrdlicka, L.4    Diggins, L.5    Singh, C.6
  • 82
    • 67049095945 scopus 로고    scopus 로고
    • Huntingtin associated protein 1 and its functions
    • doi: 10.4161/cam.3.1.7511
    • Wu, L. L., and Zhou, X. F. (2009). Huntingtin associated protein 1 and its functions. Cell Adh. Migr. 3, 71-76. doi: 10.4161/cam.3.1.7511
    • (2009) Cell Adh. Migr , vol.3 , pp. 71-76
    • Wu, L.L.1    Zhou, X.F.2
  • 83
    • 0037075624 scopus 로고    scopus 로고
    • Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease
    • doi: 10.1016/S0896-6273(02)00615-3
    • Zeron, M. M., Hansson, O., Chen, N., Wellington, C. L., Leavitt, B. R., Brundin, P., et al. (2002). Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease. Neuron 33, 849-860. doi: 10.1016/S0896-6273(02)00615-3
    • (2002) Neuron , vol.33 , pp. 849-860
    • Zeron, M.M.1    Hansson, O.2    Chen, N.3    Wellington, C.L.4    Leavitt, B.R.5    Brundin, P.6
  • 84
    • 12744279625 scopus 로고    scopus 로고
    • Transcriptional dysregulation in striatal projection- and interneurons in a mouse model of Huntington's disease: Neuronal selectivity and potential neuroprotective role of HAP1
    • doi: 10.1093/hmg/ddi014
    • Zucker, B., Luthi-Carter, R., Kama, J. A., Dunah, A. W., Stern, E. A., Fox, J. H., et al. (2005). Transcriptional dysregulation in striatal projection- and interneurons in a mouse model of Huntington's disease: neuronal selectivity and potential neuroprotective role of HAP1. Hum. Mol. Genet. 14, 179-189. doi: 10.1093/hmg/ddi014
    • (2005) Hum. Mol. Genet , vol.14 , pp. 179-189
    • Zucker, B.1    Luthi-Carter, R.2    Kama, J.A.3    Dunah, A.W.4    Stern, E.A.5    Fox, J.H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.