-
1
-
-
84867498954
-
The Prevalence of Juvenile Huntington's Disease: A Review of the Literature and Meta-analysis
-
[e4f8606b742ef3]
-
O. Quarrell, K.L. O'Donovan, O. Bandmann, and M. Strong The Prevalence of Juvenile Huntington's Disease: A Review of the Literature and Meta-analysis PLoS Curr 4 2012 [e4f8606b742ef3]
-
(2012)
PLoS Curr
, vol.4
-
-
Quarrell, O.1
O'Donovan, K.L.2
Bandmann, O.3
Strong, M.4
-
2
-
-
0021028244
-
A polymorphic DNA marker genetically linked to Huntington's disease
-
J.F. Gusella, N.S. Wexler, P.M. Conneally, S.L. Naylor, M.A. Anderson, and R.E. Tanzi et al. A polymorphic DNA marker genetically linked to Huntington's disease Nature 306 5940 1983 234 238
-
(1983)
Nature
, vol.306
, Issue.5940
, pp. 234-238
-
-
Gusella, J.F.1
Wexler, N.S.2
Conneally, P.M.3
Naylor, S.L.4
Anderson, M.A.5
Tanzi, R.E.6
-
3
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group Cell 72 6 1993 971 983
-
(1993)
Cell
, vol.72
, Issue.6
, pp. 971-983
-
-
-
4
-
-
0029089172
-
When more is less: Pathogenesis of glutamine repeat neurodegenerative diseases
-
C.A. Ross When more is less: pathogenesis of glutamine repeat neurodegenerative diseases Neuron 15 3 1995 493 496
-
(1995)
Neuron
, vol.15
, Issue.3
, pp. 493-496
-
-
Ross, C.A.1
-
5
-
-
0030919726
-
CAG repeat number governs the development rate of pathology in Huntington's disease
-
J.B. Penney Jr., J.P. Vonsattel, M.E. MacDonald, J.F. Gusella, and R.H. Myers CAG repeat number governs the development rate of pathology in Huntington's disease Ann Neurol 41 5 1997 689 692
-
(1997)
Ann Neurol
, vol.41
, Issue.5
, pp. 689-692
-
-
Penney, Jr.J.B.1
Vonsattel, J.P.2
Macdonald, M.E.3
Gusella, J.F.4
Myers, R.H.5
-
6
-
-
25844443895
-
History of genetic disease: The molecular genetics of Huntington disease - A history
-
G.P. Bates History of genetic disease: the molecular genetics of Huntington disease - a history Nat Rev Genet 6 10 2005 766 773
-
(2005)
Nat Rev Genet
, vol.6
, Issue.10
, pp. 766-773
-
-
Bates, G.P.1
-
7
-
-
33748321965
-
Predictive testing for Huntington disease: Interpretation and significance of intermediate alleles
-
A. Semaka, S. Creighton, S. Warby, and M.R. Hayden Predictive testing for Huntington disease: interpretation and significance of intermediate alleles Clin Genet 70 4 2006 283 294
-
(2006)
Clin Genet
, vol.70
, Issue.4
, pp. 283-294
-
-
Semaka, A.1
Creighton, S.2
Warby, S.3
Hayden, M.R.4
-
8
-
-
0029997090
-
Phenotypic characterization of individuals with 30-40 CAG repeats in the Huntington disease (HD) gene reveals HD cases with 36 repeats and apparently normal elderly individuals with 36-39 repeats
-
D.C. Rubinsztein, J. Leggo, R. Coles, E. Almqvist, V. Biancalana, and J.J. Cassiman et al. Phenotypic characterization of individuals with 30-40 CAG repeats in the Huntington disease (HD) gene reveals HD cases with 36 repeats and apparently normal elderly individuals with 36-39 repeats Am J Hum Genet 59 1 1996 16 22
-
(1996)
Am J Hum Genet
, vol.59
, Issue.1
, pp. 16-22
-
-
Rubinsztein, D.C.1
Leggo, J.2
Coles, R.3
Almqvist, E.4
Biancalana, V.5
Cassiman, J.J.6
-
9
-
-
0029130324
-
Anticipation and instability of IT-15 (CAG)n repeats in parent-offspring pairs with Huntington disease
-
N.G. Ranen, O.C. Stine, M.H. Abbott, M. Sherr, A.M. Codori, and M.L. Franz et al. Anticipation and instability of IT-15 (CAG)n repeats in parent-offspring pairs with Huntington disease Am J Hum Genet 57 3 1995 593 602
-
(1995)
Am J Hum Genet
, vol.57
, Issue.3
, pp. 593-602
-
-
Ranen, N.G.1
Stine, O.C.2
Abbott, M.H.3
Sherr, M.4
Codori, A.M.5
Franz, M.L.6
-
10
-
-
0027240431
-
Trinucleotide repeat length instability and age of onset in Huntington's disease
-
M. Duyao, C. Ambrose, R. Myers, A. Novelletto, F. Persichetti, and M. Frontali et al. Trinucleotide repeat length instability and age of onset in Huntington's disease Nat Genet 4 4 1993 387 392
-
(1993)
Nat Genet
, vol.4
, Issue.4
, pp. 387-392
-
-
Duyao, M.1
Ambrose, C.2
Myers, R.3
Novelletto, A.4
Persichetti, F.5
Frontali, M.6
-
11
-
-
33644783812
-
Regional and cellular gene expression changes in human Huntington's disease brain
-
A. Hodges, A.D. Strand, A.K. Aragaki, A. Kuhn, T. Sengstag, and G. Hughes et al. Regional and cellular gene expression changes in human Huntington's disease brain Hum Mol Genet 15 6 2006 965 977
-
(2006)
Hum Mol Genet
, vol.15
, Issue.6
, pp. 965-977
-
-
Hodges, A.1
Strand, A.D.2
Aragaki, A.K.3
Kuhn, A.4
Sengstag, T.5
Hughes, G.6
-
12
-
-
69949102831
-
Huntington's disease: The current state of research with peripheral tissues
-
J. Sassone, C. Colciago, G. Cislaghi, V. Silani, and A. Ciammola Huntington's disease: the current state of research with peripheral tissues Exp Neurol 219 2 2009 385 397
-
(2009)
Exp Neurol
, vol.219
, Issue.2
, pp. 385-397
-
-
Sassone, J.1
Colciago, C.2
Cislaghi, G.3
Silani, V.4
Ciammola, A.5
-
13
-
-
35348877164
-
Transcriptional signatures in Huntington's disease
-
J.H. Cha Transcriptional signatures in Huntington's disease Prog Neurobiol 83 4 2007 228 248
-
(2007)
Prog Neurobiol
, vol.83
, Issue.4
, pp. 228-248
-
-
Cha, J.H.1
-
14
-
-
34547167008
-
Proteomic profiling of plasma in Huntington's disease reveals neuroinflammatory activation and biomarker candidates
-
A. Dalrymple, E.J. Wild, R. Joubert, K. Sathasivam, M. Bjorkqvist, and A. Petersen et al. Proteomic profiling of plasma in Huntington's disease reveals neuroinflammatory activation and biomarker candidates J Proteome Res 6 7 2007 2833 2840
-
(2007)
J Proteome Res
, vol.6
, Issue.7
, pp. 2833-2840
-
-
Dalrymple, A.1
Wild, E.J.2
Joubert, R.3
Sathasivam, K.4
Bjorkqvist, M.5
Petersen, A.6
-
15
-
-
38849152224
-
Chromosomal profiles of gene expression in Huntington's disease
-
A.N. Anderson, F. Roncaroli, A. Hodges, M. Deprez, and F.E. Turkheimer Chromosomal profiles of gene expression in Huntington's disease Brain 131 Pt 2 2008 381 388
-
(2008)
Brain
, vol.131
, Issue.PART 2
, pp. 381-388
-
-
Anderson, A.N.1
Roncaroli, F.2
Hodges, A.3
Deprez, M.4
Turkheimer, F.E.5
-
16
-
-
84866925330
-
Downregulation of genes involved in metabolism and oxidative stress in the peripheral leukocytes of Huntington's disease patients
-
K.H. Chang, Y.C. Chen, Y.R. Wu, W.F. Lee, and C.M. Chen Downregulation of genes involved in metabolism and oxidative stress in the peripheral leukocytes of Huntington's disease patients PLoS One 7 9 2012 e46492
-
(2012)
PLoS One
, vol.7
, Issue.9
, pp. 46492
-
-
Chang, K.H.1
Chen, Y.C.2
Wu, Y.R.3
Lee, W.F.4
Chen, C.M.5
-
17
-
-
84874111802
-
A study of molecular changes relating to energy metabolism and cellular stress in people with Huntington's disease: Looking for biomarkers
-
J. Krzyszton-Russjan, D. Zielonka, J. Jackiewicz, S. Kusmirek, I. Bubko, and A. Klimberg et al. A study of molecular changes relating to energy metabolism and cellular stress in people with Huntington's disease: looking for biomarkers J Bioenerg Biomembr 45 1-2 2013 71 85
-
(2013)
J Bioenerg Biomembr
, vol.45
, Issue.12
, pp. 71-85
-
-
Krzyszton-Russjan, J.1
Zielonka, D.2
Jackiewicz, J.3
Kusmirek, S.4
Bubko, I.5
Klimberg, A.6
-
18
-
-
77952379669
-
Full-length huntingtin levels modulate body weight by influencing insulin-like growth factor 1 expression
-
M.A. Pouladi, Y. Xie, N.H. Skotte, D.E. Ehrnhoefer, R.K. Graham, and J.E. Kim et al. Full-length huntingtin levels modulate body weight by influencing insulin-like growth factor 1 expression Hum Mol Genet 19 8 2010 1528 1538
-
(2010)
Hum Mol Genet
, vol.19
, Issue.8
, pp. 1528-1538
-
-
Pouladi, M.A.1
Xie, Y.2
Skotte, N.H.3
Ehrnhoefer, D.E.4
Graham, R.K.5
Kim, J.E.6
-
19
-
-
33748591092
-
Oxidative stress in skin fibroblasts cultures of patients with Huntington's disease
-
P. del Hoyo, A. Garcia-Redondo, F. de Bustos, J.A. Molina, Y. Sayed, and H. Alonso-Navarro et al. Oxidative stress in skin fibroblasts cultures of patients with Huntington's disease Neurochem Res 31 9 2006 1103 1109
-
(2006)
Neurochem Res
, vol.31
, Issue.9
, pp. 1103-1109
-
-
Del Hoyo, P.1
Garcia-Redondo, A.2
De Bustos, F.3
Molina, J.A.4
Sayed, Y.5
Alonso-Navarro, H.6
-
20
-
-
0035145627
-
Reduction of glyceraldehyde-3-phosphate dehydrogenase activity in Alzheimer's disease and in Huntington's disease fibroblasts
-
J.L. Mazzola, and M.A. Sirover Reduction of glyceraldehyde-3-phosphate dehydrogenase activity in Alzheimer's disease and in Huntington's disease fibroblasts J Neurochem 76 2 2001 442 449
-
(2001)
J Neurochem
, vol.76
, Issue.2
, pp. 442-449
-
-
Mazzola, J.L.1
Sirover, M.A.2
-
21
-
-
4444303263
-
Generalized brain and skin proteasome inhibition in Huntington's disease
-
H. Seo, K.C. Sonntag, and O. Isacson Generalized brain and skin proteasome inhibition in Huntington's disease Ann Neurol 56 3 2004 319 328
-
(2004)
Ann Neurol
, vol.56
, Issue.3
, pp. 319-328
-
-
Seo, H.1
Sonntag, K.C.2
Isacson, O.3
-
22
-
-
28744458859
-
Bioconductor: Open software development for computational biology and bioinformatics
-
R.C. Gentleman, V.J. Carey, D.M. Bates, B. Bolstad, M. Dettling, and S. Dudoit et al. Bioconductor: open software development for computational biology and bioinformatics Genome Biol 5 10 2004 R80
-
(2004)
Genome Biol
, vol.5
, Issue.10
, pp. 80
-
-
Gentleman, R.C.1
Carey, V.J.2
Bates, D.M.3
Bolstad, B.4
Dettling, M.5
Dudoit, S.6
-
23
-
-
23844551199
-
Stochastic models inspired by hybridization theory for short oligonucleotide arrays
-
Z. Wu, and R.A. Irizarry Stochastic models inspired by hybridization theory for short oligonucleotide arrays J Comput Biol 12 6 2005 882 893
-
(2005)
J Comput Biol
, vol.12
, Issue.6
, pp. 882-893
-
-
Wu, Z.1
Irizarry, R.A.2
-
24
-
-
4544341015
-
Linear models and empirical bayes methods for assessing differential expression in microarray experiments
-
[Article3]
-
G.K. Smyth Linear models and empirical bayes methods for assessing differential expression in microarray experiments Stat Appl Genet Mol Biol 3 2004 [Article3]
-
(2004)
Stat Appl Genet Mol Biol
, vol.3
-
-
Smyth, G.K.1
-
26
-
-
0042121055
-
Onto-Tools, the toolkit of the modern biologist: Onto-Express, Onto-Compare, Onto-Design and Onto-Translate
-
S. Draghici, P. Khatri, P. Bhavsar, A. Shah, S.A. Krawetz, and M.A. Tainsky Onto-Tools, the toolkit of the modern biologist: Onto-Express, Onto-Compare, Onto-Design and Onto-Translate Nucleic Acids Res 31 13 2003 3775 3781
-
(2003)
Nucleic Acids Res
, vol.31
, Issue.13
, pp. 3775-3781
-
-
Draghici, S.1
Khatri, P.2
Bhavsar, P.3
Shah, A.4
Krawetz, S.A.5
Tainsky, M.A.6
-
27
-
-
0028177342
-
A CCG repeat polymorphism adjacent to the CAG repeat in the Huntington disease gene: Implications for diagnostic accuracy and predictive testing
-
S.E. Andrew, Y.P. Goldberg, J. Theilmann, J. Zeisler, and M.R. Hayden A CCG repeat polymorphism adjacent to the CAG repeat in the Huntington disease gene: implications for diagnostic accuracy and predictive testing Hum Mol Genet 3 1 1994 65 67
-
(1994)
Hum Mol Genet
, vol.3
, Issue.1
, pp. 65-67
-
-
Andrew, S.E.1
Goldberg, Y.P.2
Theilmann, J.3
Zeisler, J.4
Hayden, M.R.5
-
28
-
-
0027716510
-
Somatic instability of CTG repeat in myotonic dystrophy
-
T. Ashizawa, J.R. Dubel, and Y. Harati Somatic instability of CTG repeat in myotonic dystrophy Neurology 43 12 1993 2674 2678
-
(1993)
Neurology
, vol.43
, Issue.12
, pp. 2674-2678
-
-
Ashizawa, T.1
Dubel, J.R.2
Harati, Y.3
-
29
-
-
68049113685
-
Somatic expansion of the Huntington's disease CAG repeat in the brain is associated with an earlier age of disease onset
-
M. Swami, A.E. Hendricks, T. Gillis, T. Massood, J. Mysore, and R.H. Myers et al. Somatic expansion of the Huntington's disease CAG repeat in the brain is associated with an earlier age of disease onset Hum Mol Genet 18 16 2009 3039 3047
-
(2009)
Hum Mol Genet
, vol.18
, Issue.16
, pp. 3039-3047
-
-
Swami, M.1
Hendricks, A.E.2
Gillis, T.3
Massood, T.4
Mysore, J.5
Myers, R.H.6
-
30
-
-
38349171781
-
Comparative analysis of genetic modifiers in Drosophila points to common and distinct mechanisms of pathogenesis among polyglutamine diseases
-
J. Branco, I. Al-Ramahi, L. Ukani, A.M. Perez, P. Fernandez-Funez, and D. Rincon-Limas et al. Comparative analysis of genetic modifiers in Drosophila points to common and distinct mechanisms of pathogenesis among polyglutamine diseases Hum Mol Genet 17 3 2008 376 390
-
(2008)
Hum Mol Genet
, vol.17
, Issue.3
, pp. 376-390
-
-
Branco, J.1
Al-Ramahi, I.2
Ukani, L.3
Perez, A.M.4
Fernandez-Funez, P.5
Rincon-Limas, D.6
-
31
-
-
67649690944
-
Inhibition of Rho kinases enhances the degradation of mutant huntingtin
-
P.O. Bauer, H.K. Wong, F. Oyama, A. Goswami, M. Okuno, and Y. Kino et al. Inhibition of Rho kinases enhances the degradation of mutant huntingtin J Biol Chem 284 19 2009 13153 13164
-
(2009)
J Biol Chem
, vol.284
, Issue.19
, pp. 13153-13164
-
-
Bauer, P.O.1
Wong, H.K.2
Oyama, F.3
Goswami, A.4
Okuno, M.5
Kino, Y.6
-
32
-
-
78650279311
-
Could successful (mitochondrial) networking help prevent Huntington's disease?
-
J.M. Oliveira, and R.N. Lightowlers Could successful (mitochondrial) networking help prevent Huntington's disease? EMBO Mol Med 2 12 2010 487 489
-
(2010)
EMBO Mol Med
, vol.2
, Issue.12
, pp. 487-489
-
-
Oliveira, J.M.1
Lightowlers, R.N.2
-
33
-
-
34249715853
-
Huntingtin interacting proteins are genetic modifiers of neurodegeneration
-
L.S. Kaltenbach, E. Romero, R.R. Becklin, R. Chettier, R. Bell, and A. Phansalkar et al. Huntingtin interacting proteins are genetic modifiers of neurodegeneration PLoS Genet 3 5 2007 e82
-
(2007)
PLoS Genet
, vol.3
, Issue.5
, pp. 82
-
-
Kaltenbach, L.S.1
Romero, E.2
Becklin, R.R.3
Chettier, R.4
Bell, R.5
Phansalkar, A.6
-
34
-
-
17344392308
-
A new mathematical model for relative quantification in real-time RT-PCR
-
M.W. Pfaffl A new mathematical model for relative quantification in real-time RT-PCR Nucleic Acids Res 29 9 2001 e45
-
(2001)
Nucleic Acids Res
, vol.29
, Issue.9
, pp. 45
-
-
Pfaffl, M.W.1
-
35
-
-
33846225133
-
Huntington's disease
-
F.O. Walker Huntington's disease Lancet 369 9557 2007 218 228
-
(2007)
Lancet
, vol.369
, Issue.9557
, pp. 218-228
-
-
Walker, F.O.1
-
36
-
-
67650095269
-
Beyond the brain: Widespread pathology in Huntington's disease
-
J.M. van der Burg, M. Bjorkqvist, and P. Brundin Beyond the brain: widespread pathology in Huntington's disease Lancet Neurol 8 8 2009 765 774
-
(2009)
Lancet Neurol
, vol.8
, Issue.8
, pp. 765-774
-
-
Van Der Burg, J.M.1
Bjorkqvist, M.2
Brundin, P.3
-
37
-
-
33947388430
-
Dynamic phospholipid signaling by G protein-coupled receptors
-
P.A. Oude Weernink, L. Han, K.H. Jakobs, and M. Schmidt Dynamic phospholipid signaling by G protein-coupled receptors Biochim Biophys Acta 1768 4 2007 888 900
-
(2007)
Biochim Biophys Acta
, vol.1768
, Issue.4
, pp. 888-900
-
-
Oude Weernink, P.A.1
Han, L.2
Jakobs, K.H.3
Schmidt, M.4
-
38
-
-
84872141725
-
Expression of phosphoinositide-specific phospholipase C enzymes in human skin fibroblasts
-
V.R. Lo Vasco, M. Leopizzi, C. Chiappetta, C. Puggioni, C. Di Cristofano, and C. Della Rocca Expression of phosphoinositide-specific phospholipase C enzymes in human skin fibroblasts Connect Tissue Res 54 1 2013 1 4
-
(2013)
Connect Tissue Res
, vol.54
, Issue.1
, pp. 1-4
-
-
Lo Vasco, V.R.1
Leopizzi, M.2
Chiappetta, C.3
Puggioni, C.4
Di Cristofano, C.5
Della Rocca, C.6
-
39
-
-
0033779101
-
Structure, function, and control of phosphoinositide-specific phospholipase C
-
M.J. Rebecchi, and S.N. Pentyala Structure, function, and control of phosphoinositide-specific phospholipase C Physiol Rev 80 4 2000 1291 1335
-
(2000)
Physiol Rev
, vol.80
, Issue.4
, pp. 1291-1335
-
-
Rebecchi, M.J.1
Pentyala, S.N.2
-
40
-
-
84934876772
-
Inositol 1,4,5-tripshosphate receptor, calcium signalling and Huntington's disease
-
I. Bezprozvanny Inositol 1,4,5-tripshosphate receptor, calcium signalling and Huntington's disease Subcell Biochem 45 2007 323 335
-
(2007)
Subcell Biochem
, vol.45
, pp. 323-335
-
-
Bezprozvanny, I.1
-
41
-
-
43549111889
-
Elucidating a normal function of huntingtin by functional and microarray analysis of huntingtin-null mouse embryonic fibroblasts
-
H. Zhang, S. Das, Q.Z. Li, I. Dragatsis, J. Repa, and S. Zeitlin et al. Elucidating a normal function of huntingtin by functional and microarray analysis of huntingtin-null mouse embryonic fibroblasts BMC Neurosci 9 2008 38
-
(2008)
BMC Neurosci
, vol.9
, pp. 38
-
-
Zhang, H.1
Das, S.2
Li, Q.Z.3
Dragatsis, I.4
Repa, J.5
Zeitlin, S.6
-
42
-
-
0041963057
-
Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1
-
T.S. Tang, H. Tu, E.Y. Chan, A. Maximov, Z. Wang, and C.L. Wellington et al. Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1 Neuron 39 2 2003 227 239
-
(2003)
Neuron
, vol.39
, Issue.2
, pp. 227-239
-
-
Tang, T.S.1
Tu, H.2
Chan, E.Y.3
Maximov, A.4
Wang, Z.5
Wellington, C.L.6
-
43
-
-
76949097634
-
Abnormal morphology of peripheral cell tissues from patients with Huntington disease
-
F. Squitieri, A. Falleni, M. Cannella, S. Orobello, F. Fulceri, and P. Lenzi et al. Abnormal morphology of peripheral cell tissues from patients with Huntington disease J Neural Transm 117 1 2010 77 83
-
(2010)
J Neural Transm
, vol.117
, Issue.1
, pp. 77-83
-
-
Squitieri, F.1
Falleni, A.2
Cannella, M.3
Orobello, S.4
Fulceri, F.5
Lenzi, P.6
-
44
-
-
0034915764
-
Mechanisms underlying ubiquitination
-
C.M. Pickart Mechanisms underlying ubiquitination Annu Rev Biochem 70 2001 503 533
-
(2001)
Annu Rev Biochem
, vol.70
, pp. 503-533
-
-
Pickart, C.M.1
-
45
-
-
70350461507
-
Building ubiquitin chains: E2 enzymes at work
-
Y. Ye, and M. Rape Building ubiquitin chains: E2 enzymes at work Nat Rev Mol Cell Biol 10 11 2009 755 764
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, Issue.11
, pp. 755-764
-
-
Ye, Y.1
Rape, M.2
-
46
-
-
0036083396
-
The ubiquitin-proteasome proteolytic pathway: Destruction for the sake of construction
-
M.H. Glickman, and A. Ciechanover The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction Physiol Rev 82 2 2002 373 428
-
(2002)
Physiol Rev
, vol.82
, Issue.2
, pp. 373-428
-
-
Glickman, M.H.1
Ciechanover, A.2
-
47
-
-
11244309014
-
Proteolysis: From the lysosome to ubiquitin and the proteasome
-
A. Ciechanover Proteolysis: from the lysosome to ubiquitin and the proteasome Nat Rev Mol Cell Biol 6 1 2005 79 87
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, Issue.1
, pp. 79-87
-
-
Ciechanover, A.1
-
48
-
-
0033591363
-
Identification of the ubiquitin carrier proteins, E2s, involved in signal-induced conjugation and subsequent degradation of IkappaBalpha
-
H. Gonen, B. Bercovich, A. Orian, A. Carrano, C. Takizawa, and K. Yamanaka et al. Identification of the ubiquitin carrier proteins, E2s, involved in signal-induced conjugation and subsequent degradation of IkappaBalpha J Biol Chem 274 21 1999 14823 14830
-
(1999)
J Biol Chem
, vol.274
, Issue.21
, pp. 14823-14830
-
-
Gonen, H.1
Bercovich, B.2
Orian, A.3
Carrano, A.4
Takizawa, C.5
Yamanaka, K.6
-
49
-
-
4644307407
-
Activation of the IkappaB kinase complex and nuclear factor-kappaB contributes to mutant huntingtin neurotoxicity
-
A. Khoshnan, J. Ko, E.E. Watkin, L.A. Paige, P.H. Reinhart, and P.H. Patterson Activation of the IkappaB kinase complex and nuclear factor-kappaB contributes to mutant huntingtin neurotoxicity J Neurosci 24 37 2004 7999 8008
-
(2004)
J Neurosci
, vol.24
, Issue.37
, pp. 7999-8008
-
-
Khoshnan, A.1
Ko, J.2
Watkin, E.E.3
Paige, L.A.4
Reinhart, P.H.5
Patterson, P.H.6
-
50
-
-
0038024241
-
Rocks: Multifunctional kinases in cell behaviour
-
K. Riento, and A.J. Ridley Rocks: multifunctional kinases in cell behaviour Nat Rev Mol Cell Biol 4 6 2003 446 456
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, Issue.6
, pp. 446-456
-
-
Riento, K.1
Ridley, A.J.2
-
51
-
-
0242657586
-
A rapid cellular FRET assay of polyglutamine aggregation identifies a novel inhibitor
-
S.K. Pollitt, J. Pallos, J. Shao, U.A. Desai, A.A. Ma, and L.M. Thompson et al. A rapid cellular FRET assay of polyglutamine aggregation identifies a novel inhibitor Neuron 40 4 2003 685 694
-
(2003)
Neuron
, vol.40
, Issue.4
, pp. 685-694
-
-
Pollitt, S.K.1
Pallos, J.2
Shao, J.3
Desai, U.A.4
Ma, A.A.5
Thompson, L.M.6
-
52
-
-
84865318493
-
ROCK-phosphorylated vimentin modifies mutant huntingtin aggregation via sequestration of IRBIT
-
P.O. Bauer, R. Hudec, A. Goswami, M. Kurosawa, G. Matsumoto, and K. Mikoshiba et al. ROCK-phosphorylated vimentin modifies mutant huntingtin aggregation via sequestration of IRBIT Mol Neurodegener 7 2012 43
-
(2012)
Mol Neurodegener
, vol.7
, pp. 43
-
-
Bauer, P.O.1
Hudec, R.2
Goswami, A.3
Kurosawa, M.4
Matsumoto, G.5
Mikoshiba, K.6
-
53
-
-
0035496104
-
APC, signal transduction and genetic instability in colorectal cancer
-
R. Fodde, R. Smits, and H. Clevers APC, signal transduction and genetic instability in colorectal cancer Nat Rev Cancer 1 1 2001 55 67
-
(2001)
Nat Rev Cancer
, vol.1
, Issue.1
, pp. 55-67
-
-
Fodde, R.1
Smits, R.2
Clevers, H.3
-
54
-
-
79960899591
-
Beta-catenin as a potential key target for tumor suppression
-
Y. Fu, S. Zheng, N. An, T. Athanasopoulos, L. Popplewell, and A. Liang et al. Beta-catenin as a potential key target for tumor suppression Int J Cancer 129 7 2011 1541 1551
-
(2011)
Int J Cancer
, vol.129
, Issue.7
, pp. 1541-1551
-
-
Fu, Y.1
Zheng, S.2
An, N.3
Athanasopoulos, T.4
Popplewell, L.5
Liang, A.6
-
55
-
-
67650230896
-
Wnt/beta-catenin signaling: Components, mechanisms, and diseases
-
B.T. MacDonald, K. Tamai, and X. He Wnt/beta-catenin signaling: components, mechanisms, and diseases Dev Cell 17 1 2009 9 26
-
(2009)
Dev Cell
, vol.17
, Issue.1
, pp. 9-26
-
-
Macdonald, B.T.1
Tamai, K.2
He, X.3
-
56
-
-
84862759032
-
Huntington's disease and its therapeutic target genes: A global functional profile based on the HD Research Crossroads database
-
R.K. Kalathur, M.A. Hernandez-Prieto, and M.E. Futschik Huntington's disease and its therapeutic target genes: a global functional profile based on the HD Research Crossroads database BMC Neurol 12 2012 47
-
(2012)
BMC Neurol
, vol.12
, pp. 47
-
-
Kalathur, R.K.1
Hernandez-Prieto, M.A.2
Futschik, M.E.3
-
57
-
-
77954886545
-
Mutant huntingtin-impaired degradation of beta-catenin causes neurotoxicity in Huntington's disease
-
J.D. Godin, G. Poizat, M.A. Hickey, F. Maschat, and S. Humbert Mutant huntingtin-impaired degradation of beta-catenin causes neurotoxicity in Huntington's disease EMBO J 29 14 2010 2433 2445
-
(2010)
EMBO J
, vol.29
, Issue.14
, pp. 2433-2445
-
-
Godin, J.D.1
Poizat, G.2
Hickey, M.A.3
Maschat, F.4
Humbert, S.5
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