Vascular endothelial growth factor: A novel endocrine defensive response to hypoglycemia

Journal of Clinical Endocrinology and Metabolism

Volumn 87, Issue 2, 2002, Pages 835-840

  Dantz, Dorle ^a   Bewersdorf, Jan ^a   Fruehwald Schultes, Bernd ^a   Kern, Werner ^a   Jelkmann, Wolfgang ^a   Born, Jan ^a   Fehm, Horst L ^a   Peters, Achim ^a  

^a UNIVERSITY OF LÜBECK   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; VASCULOTROPIN;

ADAPTATION; ADRENERGIC SYSTEM; ADULT; ARTICLE; BLOOD BRAIN BARRIER; BLOOD VESSEL; CONTROLLED STUDY; GLUCOSE TRANSPORT; HUMAN; HUMAN EXPERIMENT; HYPOGLYCEMIA; MALE; NORMAL HUMAN; PRIORITY JOURNAL;

EID: 0036173406     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jcem.87.2.8215     Document Type: Article

References (45)

1. Glucose transporters and insulin action-implications for insulin resistance and diabetes mellitus
2. GLUT-1 deficiency syndrome caused by haplo insufficiency of the blood-brain barrier hexose carrier
3. Change in hexose distribution volume and fractional utilization of [18F]-2-deoxy-2fluoro-D-glucose in brain during acute hypoglycemia in humans
4. Hypoglycemia unawareness
5. Hypoglycemia
6. Adaptation to mild hypoglycaemia in normal subjects despite sustained increases in counter-regulatory hormones
7. Patients with type 1 diabetes adapt acutely to sustained mild hypoglycaemia
8. Brain glucose uptake and unawareness of hypoglycemia in patients with insulin-dependent diabetes mellitus
9. Upregulation of blood-brain barrier GLUT1 glucose transporter protein and mRNA in experimental chronic hypoglycemia
10. Molecular and biological properties of the vascular endothelial growth factor family of proteins
11. Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid
12. Binding sites for vascular endothelial growth factor are localized on endothelial cells in adult rat tissues
13. Endothelial cells in physiology and in the pathophysiology of vascular disorders
14. Regulation of hexose transport in aortic endothelial cells by vascular permeability factor and tumor necrosis factor-alpha, but not by insulin
15. Enhancement of glucose transport by vascular endothelial growth factor in retinal endothelial cells
16. Vascular endothelial growth factor induces endothelial fenestrations in vitro
17. Pathways of macromolecular extravasation across microvascular endothelium in response to VPF/VEGF and other vasoactive mediators
18. Vascular endothelial growth factor affects permeability of brain microvessel endothelial cells in vitro
19. Effects of vascular permeability factor on the permeability of cultured endothelial cells from brain capillaries
20. VEGF increases permeability of the blood-brain barrier via a nitric oxide synthase/cGMP-dependent pathway
21. Vascular endothelial growth factor VEGF stimulates angiogenesis in good and bad situations
22. Hierarchy of glycemic thresholds for counterregulatory hormone secretion, symptoms, and cerebral dysfunction
23. Brain glucose sensing and body energy homoeostasis: Role in obesity and diabetes
24. Hypothalamic glucose sensor
25. Local ventromedial hypothalamus glucopenia triggers counterregulatory hormone release
26. Local ventromedial hypothalamus glucose perfusion blocks counterregulation during systemic hypoglycemia in awake rats
27. PACAP gene expression in neurons of the rat hypothalamo-pituitary-adrenocortical axis is induced by endotoxin and interleukin-1beta
28. Pituitary, adenylate cyclase-activating peptide gene expression in corticotropin-releasing factor-containing parvicellular neurons of the rat hypothalamic paraventricular nucleus is induced by colchicine, but not by adrenalectomy, acute osmotic, ether, or restraint stress
29. Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells
30. Pattern and localisation of expression of vascular endothelial growth factor and its receptor fit-1 in the ovine pituitary gland: Expression is independent of hypothalamic control
31. Pituitary adenylate cyclase-activating polypeptide, interleukin-6 and glucocorticoids regulate the release of vascular endothelial growth factor in pituitary folliculostellate cells
32. Stabilization of vascular endothelial growth factor mRNA by hypoxia and hypoglycemia and coregulation with other ischemia-induced genes
33. Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: Implications for tumor angiogenesis
34. Vascular endothelial growth factor is induced by long-term high glucose concentration and up-regulated by acute glucose deprivation in cultured bovine retinal pigmented epithelial cells
35. Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT
36. Up-regulation of vascular endothelial growth factor in response to glucose deprivation
37. The ubiquitous glucose transporter GLUT-1 belongs to the glucose-regulated protein family of stress-inducible proteins
38. Norepinephrine induces vascular endothelial growth factor gene expression in brown adipocytes through a beta-adrenoreceptor/cAMP/protein kinase A pathway involving Src but independently of Erk1/2
39. Role of sympathetic activity in controlling the expression of vascular endothelial growth factor in brown fat cells of lean and genetically obese rats
40. Adrenergic activation of vascular endothelial growth factor mRNA expression in rat brown adipose tissue: Implication in cold-induced angiogenesis
41. Glucose metabolism rather than insulin is a main determinant of leptin secretion in humans
42. Glucose-induced protein kinase C activation regulates vascular permeability factor mRNA expression and peptide production by human vascular smooth muscle cells in vitro
43. Effects of high glucose on vascular endothelial growth factor expression in vascular smooth muscle cells
44. Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha/ARNT
45. Reciprocal positive regulation of hypoxia-inducible factor 1alpha and insulin-like growth factor 2