-
1
-
-
84883711556
-
Incorporation of histone derived recombinant protein for enhanced disassembly of core-membrane structured liposomal nanoparticles for efficient siRNA delivery
-
Wang Y, Zhang L, Guo S, HatefiA, Huang L (2013) Incorporation of histone derived recombinant protein for enhanced disassembly of core-membrane structured liposomal nanoparticles for efficient siRNA delivery. J Controlled Release Off J Controlled Release Soc 172(1):179-189. doi:10.1016/j.jconrel.2013.08.015
-
(2013)
J Controlled Release Off J Controlled Release Soc
, vol.172
, Issue.1
, pp. 179-189
-
-
Wang, Y.1
Zhang, L.2
Guo, S.3
Hatefi, A.4
Huang, L.5
-
2
-
-
84856638259
-
Clinical development of liposome-based drugs: Formulation, characterization, and therapeutic efficacy
-
Chang HI, Yeh MK (2012) Clinical development of liposome-based drugs: formulation, characterization, and therapeutic efficacy. Int J Nanomed 7:49-60. doi:10.2147/IJN.S26766
-
(2012)
Int J Nanomed
, vol.7
, pp. 49-60
-
-
Chang, H.I.1
Yeh, M.K.2
-
3
-
-
79960078032
-
Tumor targeted quantum dot-mucin 1 aptamer-doxorubicin conjugate for imaging and treatment of cancer
-
Savla R, Taratula O, Garbuzenko O, Minko T (2011) Tumor targeted quantum dot-mucin 1 aptamer-doxorubicin conjugate for imaging and treatment of cancer. J Controlled Release Off J Controlled Release Soc 153(1):16-22. doi:10.1016/j.jconrel.2011.02.015
-
(2011)
J Controlled Release Off J Controlled Release Soc
, vol.153
, Issue.1
, pp. 16-22
-
-
Savla, R.1
Taratula, O.2
Garbuzenko, O.3
Minko, T.4
-
4
-
-
74949102605
-
InAs(ZnCdS) quantum dots optimized for biological imaging in the near-infrared
-
Allen PM, Liu W, Chauhan VP, Lee J, Ting AY, Fukumura D, Jain RK, Bawendi MG (2010) InAs(ZnCdS) quantum dots optimized for biological imaging in the near-infrared. J Am Chem Soc 132(2):470-471. doi:10.1021/ja908250r
-
(2010)
J Am Chem Soc
, vol.132
, Issue.2
, pp. 470-471
-
-
Allen, P.M.1
Liu, W.2
Chauhan, V.P.3
Lee, J.4
Ting, A.Y.5
Fukumura, D.6
Jain, R.K.7
Bawendi, M.G.8
-
5
-
-
79953054576
-
The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect
-
Fang J, Nakamura H, Maeda H (2011) The EPR effect: unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect. Adv Drug Deliv Rev 63(3):136-151. doi:10.1016/j.addr.2010.04.009
-
(2011)
Adv Drug Deliv Rev
, vol.63
, Issue.3
, pp. 136-151
-
-
Fang, J.1
Nakamura, H.2
Maeda, H.3
-
6
-
-
84919642689
-
Nanoparticle targeting of anti-cancer drugs that alter intracellular signaling or influence the tumor microenvironment
-
Kanapathipillai M, Brock A, Ingber DE (2014) Nanoparticle targeting of anti-cancer drugs that alter intracellular signaling or influence the tumor microenvironment. Adv Drug Deliv Rev. doi:10.1016/j.addr.2014.05.005
-
(2014)
Adv Drug Deliv Rev
-
-
Kanapathipillai, M.1
Brock, A.2
Ingber, D.E.3
-
7
-
-
84906054311
-
Human pathological basis of blood vessels and stromal tissue for nanotechnology
-
Nishihara H (2014) Human pathological basis of blood vessels and stromal tissue for nanotechnology. Adv Drug Deliv Rev 74C:19-27. doi:10.1016/j.addr.2014.01.005
-
(2014)
Adv Drug Deliv Rev
, vol.74 C
, pp. 19-27
-
-
Nishihara, H.1
-
8
-
-
79952143791
-
Exploring solid lipid nanoparticles to enhance the oral bioavailability of curcumin
-
Kakkar V, Singh S, Singla D, Kaur IP (2011) Exploring solid lipid nanoparticles to enhance the oral bioavailability of curcumin. Mol Nutr Food Res 55(3):495-503. doi:10.1002/mnfr. 201000310
-
(2011)
Mol Nutr Food Res
, vol.55
, Issue.3
, pp. 495-503
-
-
Kakkar, V.1
Singh, S.2
Singla, D.3
Kaur, I.P.4
-
9
-
-
79951906181
-
Functionalized mesoporous silica nanoparticlebased visible light responsive controlled release delivery system
-
Knezevic NZ, Trewyn BG, Lin VS (2011) Functionalized mesoporous silica nanoparticlebased visible light responsive controlled release delivery system. Chem Commun 47 (10):2817-2819. doi:10.1039/c0cc04424e
-
(2011)
Chem Commun
, vol.47
, Issue.10
, pp. 2817-2819
-
-
Knezevic, N.Z.1
Trewyn, B.G.2
Lin, V.S.3
-
10
-
-
84855813140
-
Albumin-based nanoparticles as potential controlled release drug delivery systems
-
Elzoghby AO, Samy WM, Elgindy NA (2012) Albumin-based nanoparticles as potential controlled release drug delivery systems. J Controlled Release Off J Controlled Release Soc 157(2):168-182. doi:10.1016/j.jconrel.2011.07.031
-
(2012)
J Controlled Release Off J Controlled Release Soc
, vol.157
, Issue.2
, pp. 168-182
-
-
Elzoghby, A.O.1
Samy, W.M.2
Elgindy, N.A.3
-
11
-
-
0025341615
-
Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes
-
Klibanov AL, Maruyama K, Torchilin VP, Huang L (1990) Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes. FEBS Lett 268 (1):235-237
-
(1990)
FEBS Lett
, vol.268
, Issue.1
, pp. 235-237
-
-
Klibanov, A.L.1
Maruyama, K.2
Torchilin, V.P.3
Huang, L.4
-
12
-
-
84887419715
-
Biodistribution and pharmacokinetics of uniform magnetite nanoparticles chemically modified with polyethylene glycol
-
Ruiz A, Hernandez Y, Cabal C, Gonzalez E, Veintemillas-Verdaguer S, Martinez E, Morales MP (2013) Biodistribution and pharmacokinetics of uniform magnetite nanoparticles chemically modified with polyethylene glycol. Nanoscale 5(23):11400-11408. doi:10.1039/ c3nr01412f
-
(2013)
Nanoscale
, vol.5
, Issue.23
, pp. 11400-11408
-
-
Ruiz, A.1
Hernandez, Y.2
Cabal, C.3
Gonzalez, E.4
Veintemillas-Verdaguer, S.5
Martinez, E.6
Morales, M.P.7
-
13
-
-
15044353995
-
Pharmacokinetics and biodistribution of RGD-targeted doxorubicin-loaded nanoparticles in tumor-bearing mice
-
Bibby DC, Talmadge JE, Dalal MK, Kurz SG, Chytil KM, Barry SE, Shand DG, Steiert M (2005) Pharmacokinetics and biodistribution of RGD-targeted doxorubicin-loaded nanoparticles in tumor-bearing mice. Int J Pharm 293(1-2):281-290. doi:10.1016/j. ijpharm.2004.12.021
-
(2005)
Int J Pharm
, vol.293
, Issue.1-2
, pp. 281-290
-
-
Bibby, D.C.1
Talmadge, J.E.2
Dalal, M.K.3
Kurz, S.G.4
Chytil, K.M.5
Barry, S.E.6
Shand, D.G.7
Steiert, M.8
-
14
-
-
78049452610
-
Delivering nanomedicine to solid tumors
-
Jain RK, Stylianopoulos T (2010) Delivering nanomedicine to solid tumors. Nat Rev Clin Oncol 7(11):653-664. doi:10.1038/nrclinonc.2010.139
-
(2010)
Nat Rev Clin Oncol
, vol.7
, Issue.11
, pp. 653-664
-
-
Jain, R.K.1
Stylianopoulos, T.2
-
15
-
-
84901684242
-
Co-delivery of cisplatin and rapamycin for enhanced anticancer therapy through synergistic effects and microenvironment modulation
-
Guo S, Lin CM, Xu Z, Miao L, Wang Y, Huang L (2014) Co-delivery of cisplatin and rapamycin for enhanced anticancer therapy through synergistic effects and microenvironment modulation. ACS Nano. doi:10.1021/nn5010815
-
(2014)
ACS Nano
-
-
Guo, S.1
Lin, C.M.2
Xu, Z.3
Miao, L.4
Wang, Y.5
Huang, L.6
-
16
-
-
84884278759
-
Multifunctional nanoparticles co-delivering Trp2 peptide and CpG adjuvant induce potent cytotoxic T-lymphocyte response against melanoma and its lung metastasis
-
Xu Z, Ramishetti S, Tseng YC, Guo S, Wang Y, Huang L (2013) Multifunctional nanoparticles co-delivering Trp2 peptide and CpG adjuvant induce potent cytotoxic T-lymphocyte response against melanoma and its lung metastasis. J Control Release 172 (1):259-265. doi:10.1016/j.jconrel.2013.08.021
-
(2013)
J Control Release
, vol.172
, Issue.1
, pp. 259-265
-
-
Xu, Z.1
Ramishetti, S.2
Tseng, Y.C.3
Guo, S.4
Wang, Y.5
Huang, L.6
-
17
-
-
84881670536
-
Combinational delivery of c-myc siRNA and nucleoside analogs in a single, synthetic nanocarrier for targeted cancer therapy
-
Zhang Y, Peng L, Mumper RJ, Huang L (2013) Combinational delivery of c-myc siRNA and nucleoside analogs in a single, synthetic nanocarrier for targeted cancer therapy. Biomaterials 34(33):8459-8468. doi:10.1016/j.biomaterials.2013.07.050
-
(2013)
Biomaterials
, vol.34
, Issue.33
, pp. 8459-8468
-
-
Zhang, Y.1
Peng, L.2
Mumper, R.J.3
Huang, L.4
-
18
-
-
79955007145
-
The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers
-
Ashley CE, Carnes EC, Phillips GK, Padilla D, Durfee PN, Brown PA, Hanna TN, Liu J, Phillips B, Carter MB, Carroll NJ, Jiang X, Dunphy DR, Willman CL, Petsev DN, Evans DG, Parikh AN, Chackerian B, Wharton W, Peabody DS, Brinker CJ (2011) The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers. Nat Mater 10(5):389-397. doi:10.1038/nmat2992
-
(2011)
Nat Mater
, vol.10
, Issue.5
, pp. 389-397
-
-
Ashley, C.E.1
Carnes, E.C.2
Phillips, G.K.3
Padilla, D.4
Durfee, P.N.5
Brown, P.A.6
Hanna, T.N.7
Liu, J.8
Phillips, B.9
Carter, M.B.10
Carroll, N.J.11
Jiang, X.12
Dunphy, D.R.13
Willman, C.L.14
Petsev, D.N.15
Evans, D.G.16
Parikh, A.N.17
Chackerian, B.18
Wharton, W.19
Peabody, D.S.20
Brinker, C.J.21
more..
-
19
-
-
79961050017
-
Polymeric nanoparticles with precise ratiometric control over drug loading for combination therapy
-
Aryal S, Hu CM, Zhang L (2011) Polymeric nanoparticles with precise ratiometric control over drug loading for combination therapy. Mol Pharm 8(4):1401-1407. doi:10.1021/ mp200243k
-
(2011)
Mol Pharm
, vol.8
, Issue.4
, pp. 1401-1407
-
-
Aryal, S.1
Hu, C.M.2
Zhang, L.3
-
20
-
-
78149260773
-
Engineering of self-assembled nanoparticle platform for precisely controlled combination drug therapy
-
Kolishetti N, Dhar S, Valencia PM, Lin LQ, Karnik R, Lippard SJ, Langer R, Farokhzad OC (2010) Engineering of self-assembled nanoparticle platform for precisely controlled combination drug therapy. Proc Natl Acad Sci USA 107(42):17939-17944. doi:10.1073/ pnas.1011368107
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.42
, pp. 17939-17944
-
-
Kolishetti, N.1
Dhar, S.2
Valencia, P.M.3
Lin, L.Q.4
Karnik, R.5
Lippard, S.J.6
Langer, R.7
Farokhzad, O.C.8
-
21
-
-
83455247330
-
Multifunctional mesoporous silica nanospheres with cleavable Gd(III) chelates as MRI contrast agents: Synthesis, characterization, target-specificity, and renal clearance
-
Vivero-Escoto JL, Taylor-Pashow KM, Huxford RC, Della Rocca J, Okoruwa C, An H, Lin W, Lin W (2011) Multifunctional mesoporous silica nanospheres with cleavable Gd(III) chelates as MRI contrast agents: synthesis, characterization, target-specificity, and renal clearance. Small 7(24):3519-3528. doi:10.1002/smll.201100521
-
(2011)
Small
, vol.7
, Issue.24
, pp. 3519-3528
-
-
Vivero-Escoto, J.L.1
Taylor-Pashow, K.M.2
Huxford, R.C.3
Della Rocca, J.4
Okoruwa, C.5
An, H.6
Lin, W.7
Lin, W.8
-
22
-
-
77952856581
-
Nanocomposites with spatially separated functionalities for combined imaging and magnetolytic therapy
-
Hu SH, Gao X (2010) Nanocomposites with spatially separated functionalities for combined imaging and magnetolytic therapy. J Am Chem Soc 132(21):7234-7237. doi:10.1021/ ja102489q
-
(2010)
J Am Chem Soc
, vol.132
, Issue.21
, pp. 7234-7237
-
-
Hu, S.H.1
Gao, X.2
-
23
-
-
33846160552
-
Multifunctional polymeric micelles as cancer-targeted, MRI-ultrasensitive drug delivery systems
-
Nasongkla N, Bey E, Ren J, Ai H, Khemtong C, Guthi JS, Chin SF, Sherry AD, Boothman DA, Gao J (2006) Multifunctional polymeric micelles as cancer-targeted, MRI-ultrasensitive drug delivery systems. Nano Lett 6(11):2427-2430. doi:10.1021/nl061412u
-
(2006)
Nano Lett
, vol.6
, Issue.11
, pp. 2427-2430
-
-
Nasongkla, N.1
Bey, E.2
Ren, J.3
Ai, H.4
Khemtong, C.5
Guthi, J.S.6
Chin, S.F.7
Sherry, A.D.8
Boothman, D.A.9
Gao, J.10
-
24
-
-
11144279276
-
cRGDfunctionalized polymer micelles for targeted doxorubicin delivery
-
Nasongkla N, Shuai X, Ai H, Weinberg BD, Pink J, Boothman DA, Gao J (2004) cRGDfunctionalized polymer micelles for targeted doxorubicin delivery. Angew Chem Int Ed Engl 43(46):6323-6327. doi:10.1002/anie.200460800
-
(2004)
Angew Chem Int Ed Engl
, vol.43
, Issue.46
, pp. 6323-6327
-
-
Nasongkla, N.1
Shuai, X.2
Ai, H.3
Weinberg, B.D.4
Pink, J.5
Boothman, D.A.6
Gao, J.7
-
25
-
-
7044231886
-
Anisamide-targeted stealth liposomes: A potent carrier for targeting doxorubicin to human prostate cancer cells
-
Banerjee R, Tyagi P, Li S, Huang L (2004) Anisamide-targeted stealth liposomes: a potent carrier for targeting doxorubicin to human prostate cancer cells. Int J Cancer 112(4):693-700. doi:10.1002/ijc.20452
-
(2004)
Int J Cancer
, vol.112
, Issue.4
, pp. 693-700
-
-
Banerjee, R.1
Tyagi, P.2
Li, S.3
Huang, L.4
-
26
-
-
74249101977
-
Therapeutic nanoparticles to combat cancer drug resistance
-
Hu CM, Zhang L (2009) Therapeutic nanoparticles to combat cancer drug resistance. Curr Drug Metab 10(8):836-841
-
(2009)
Curr Drug Metab
, vol.10
, Issue.8
, pp. 836-841
-
-
Hu, C.M.1
Zhang, L.2
-
27
-
-
84862830732
-
Nanoparticle-based combination therapy toward overcoming drug resistance in cancer
-
Hu CM, Zhang L (2012) Nanoparticle-based combination therapy toward overcoming drug resistance in cancer. Biochem Pharmacol 83(8):1104-1111. doi:10.1016/j.bcp.2012.01.008
-
(2012)
Biochem Pharmacol
, vol.83
, Issue.8
, pp. 1104-1111
-
-
Hu, C.M.1
Zhang, L.2
-
28
-
-
84859771379
-
Molecular mechanisms of cisplatin resistance
-
Galluzzi L, Senovilla L, Vitale I, Michels J, Martins I, Kepp O, Castedo M, Kroemer G (2012) Molecular mechanisms of cisplatin resistance. Oncogene 31(15):1869-1883. doi:10. 1038/onc.2011.384
-
(2012)
Oncogene
, vol.31
, Issue.15
, pp. 1869-1883
-
-
Galluzzi, L.1
Senovilla, L.2
Vitale, I.3
Michels, J.4
Martins, I.5
Kepp, O.6
Castedo, M.7
Kroemer, G.8
-
29
-
-
63149190290
-
High cytotoxicity of cisplatin nanocapsules in ovarian carcinoma cells depends on uptake by caveolae-mediated endocytosis
-
Hamelers IH, Staffhorst RW, Voortman J, de Kruijff B, Reedijk J, van Bergen en Henegouwen PM, de Kroon AI (2009) High cytotoxicity of cisplatin nanocapsules in ovarian carcinoma cells depends on uptake by caveolae-mediated endocytosis. Clinical Cancer Res Off J Am Assoc Cancer Res 15(4):1259-1268. doi:10.1158/1078-0432.CCR-08-1702
-
(2009)
Clinical Cancer Res Off J Am Assoc Cancer Res
, vol.15
, Issue.4
, pp. 1259-1268
-
-
Hamelers, I.H.1
Staffhorst, R.W.2
Voortman, J.3
de Kruijff, B.4
Reedijk, J.5
van Bergen en Henegouwen, P.M.6
de Kroon, A.I.7
-
30
-
-
84872401360
-
A review of current nanoparticle and targeting moieties for the delivery of cancer therapeutics
-
Steichen SD, Caldorera-Moore M, Peppas NA (2012) A review of current nanoparticle and targeting moieties for the delivery of cancer therapeutics. Eur J Pharm Sci Off J Eur Fed Pharm Sci 48(3):416-427. doi:10.1016/j.ejps.2012.12.006
-
(2012)
Eur J Pharm Sci Off J Eur Fed Pharm Sci
, vol.48
, Issue.3
, pp. 416-427
-
-
Steichen, S.D.1
Caldorera-Moore, M.2
Peppas, N.A.3
-
31
-
-
51049090204
-
Nanoparticle therapeutics: An emerging treatment modality for cancer
-
Davis ME, Chen ZG, Shin DM (2008) Nanoparticle therapeutics: an emerging treatment modality for cancer. Nat Rev Drug Discov 7(9):771-782. doi:10.1038/nrd2614
-
(2008)
Nat Rev Drug Discov
, vol.7
, Issue.9
, pp. 771-782
-
-
Davis, M.E.1
Chen, Z.G.2
Shin, D.M.3
-
32
-
-
84885432555
-
Update on current and potential nanoparticle cancer therapies
-
Rink JS, Plebanek MP, Tripathy S, Thaxton CS (2013) Update on current and potential nanoparticle cancer therapies. Curr Opin Oncol 25(6):646-651. doi:10.1097/CCO. 0000000000000012
-
(2013)
Curr Opin Oncol
, vol.25
, Issue.6
, pp. 646-651
-
-
Rink, J.S.1
Plebanek, M.P.2
Tripathy, S.3
Thaxton, C.S.4
-
33
-
-
18844428327
-
Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
-
Orimo A, Gupta PB, Sgroi DC, Arenzana-Seisdedos F, Delaunay T, Naeem R, Carey VJ, Richardson AL, Weinberg RA (2005) Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 121(3):335-348. doi:10.1016/j.cell.2005.02.034
-
(2005)
Cell
, vol.121
, Issue.3
, pp. 335-348
-
-
Orimo, A.1
Gupta, P.B.2
Sgroi, D.C.3
Arenzana-Seisdedos, F.4
Delaunay, T.5
Naeem, R.6
Carey, V.J.7
Richardson, A.L.8
Weinberg, R.A.9
-
34
-
-
79957894276
-
Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases
-
Carmeliet P, Jain RK (2011) Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases. Nat Rev Drug Discov 10(6):417-427. doi:10.1038/nrd3455
-
(2011)
Nat Rev Drug Discov
, vol.10
, Issue.6
, pp. 417-427
-
-
Carmeliet, P.1
Jain, R.K.2
-
36
-
-
0142151097
-
Abnormalities of basement membrane on blood vessels and endothelial sprouts in tumors
-
Baluk P, Morikawa S, Haskell A, Mancuso M, McDonald DM (2003) Abnormalities of basement membrane on blood vessels and endothelial sprouts in tumors. Am J Pathol 163 (5):1801-1815. doi:10.1016/S0002-9440(10)63540-7
-
(2003)
Am J Pathol
, vol.163
, Issue.5
, pp. 1801-1815
-
-
Baluk, P.1
Morikawa, S.2
Haskell, A.3
Mancuso, M.4
McDonald, D.M.5
-
37
-
-
84872088791
-
Pericyte coverage of differentiated vessels inside tumor vasculature is an independent unfavorable prognostic factor for patients with clear cell renal cell carcinoma
-
Cao Y, Zhang ZL, Zhou M, Elson P, Rini B, Aydin H, Feenstra K, Tan MH, Berghuis B, Tabbey R, Resau JH, Zhou FJ, Teh BT, Qian CN (2013) Pericyte coverage of differentiated vessels inside tumor vasculature is an independent unfavorable prognostic factor for patients with clear cell renal cell carcinoma. Cancer 119(2):313-324. doi:10.1002/cncr.27746
-
(2013)
Cancer
, vol.119
, Issue.2
, pp. 313-324
-
-
Cao, Y.1
Zhang, Z.L.2
Zhou, M.3
Elson, P.4
Rini, B.5
Aydin, H.6
Feenstra, K.7
Tan, M.H.8
Berghuis, B.9
Tabbey, R.10
Resau, J.H.11
Zhou, F.J.12
Teh, B.T.13
Qian, C.N.14
-
38
-
-
84899623873
-
Microenvironment: Tumour-promoting tissue mechanics
-
Lokody I (2014) Microenvironment: tumour-promoting tissue mechanics. Nat Rev Cancer 14 (5):296. doi:10.1038/nrc3727
-
(2014)
Nat Rev Cancer
, vol.14
, Issue.5
, pp. 296
-
-
Lokody, I.1
-
39
-
-
84861781110
-
Studying primary tumor-associated fibroblast involvement in cancer metastasis in mice
-
Duyverman AM, Steller EJ, Fukumura D, Jain RK, Duda DG (2012) Studying primary tumor-associated fibroblast involvement in cancer metastasis in mice. Nat Protoc 7(4):756-762. doi:10.1038/nprot.2012.031
-
(2012)
Nat Protoc
, vol.7
, Issue.4
, pp. 756-762
-
-
Duyverman, A.M.1
Steller, E.J.2
Fukumura, D.3
Jain, R.K.4
Duda, D.G.5
-
41
-
-
77957221459
-
Dynamic interplay between the collagen scaffold and tumor evolution
-
Egeblad M, Rasch MG, Weaver VM (2010) Dynamic interplay between the collagen scaffold and tumor evolution. Curr Opin Cell Biol 22(5):697-706. doi:10.1016/j.ceb.2010.08.015
-
(2010)
Curr Opin Cell Biol
, vol.22
, Issue.5
, pp. 697-706
-
-
Egeblad, M.1
Rasch, M.G.2
Weaver, V.M.3
-
42
-
-
78249280008
-
High-molecular-weight hyaluronan is a novel inhibitor of pulmonary vascular leakiness
-
Singleton PA, Mirzapoiazova T, Guo Y, Sammani S, Mambetsariev N, Lennon FE, Moreno- Vinasco L, Garcia JG (2010) High-molecular-weight hyaluronan is a novel inhibitor of pulmonary vascular leakiness. Am J Physiol Lung Cell Mol Physiol 299(5):L639-L651. doi:10.1152/ajplung.00405.2009
-
(2010)
Am J Physiol Lung Cell Mol Physiol
, vol.299
, Issue.5
, pp. L639-L651
-
-
Singleton, P.A.1
Mirzapoiazova, T.2
Guo, Y.3
Sammani, S.4
Mambetsariev, N.5
Lennon, F.E.6
Moreno- Vinasco, L.7
Garcia, J.G.8
-
43
-
-
84864285794
-
Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion
-
Straussman R, Morikawa T, Shee K, Barzily-Rokni M, Qian ZR, Du J, Davis A, Mongare MM, Gould J, Frederick DT, Cooper ZA, Chapman PB, Solit DB, Ribas A, Lo RS, Flaherty KT, Ogino S, Wargo JA, Golub TR (2012) Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion. Nature 487(7408):500-504. doi:10. 1038/nature11183
-
(2012)
Nature
, vol.487
, Issue.7408
, pp. 500-504
-
-
Straussman, R.1
Morikawa, T.2
Shee, K.3
Barzily-Rokni, M.4
Qian, Z.R.5
Du, J.6
Davis, A.7
Mongare, M.M.8
Gould, J.9
Frederick, D.T.10
Cooper, Z.A.11
Chapman, P.B.12
Solit, D.B.13
Ribas, A.14
Lo, R.S.15
Flaherty, K.T.16
Ogino, S.17
Wargo, J.A.18
Golub, T.R.19
-
44
-
-
34447276000
-
Tumor microenvironment: The role of the tumor stroma in cancer
-
Li H, Fan X, Houghton J (2007) Tumor microenvironment: the role of the tumor stroma in cancer. J Cell Biochem 101(4):805-815. doi:10.1002/jcb.21159
-
(2007)
J Cell Biochem
, vol.101
, Issue.4
, pp. 805-815
-
-
Li, H.1
Fan, X.2
Houghton, J.3
-
45
-
-
84878257355
-
Porous silicon nanocarriers for dual targeting tumor associated endothelial cells and macrophages in stroma of orthotopic human pancreatic cancers
-
Yokoi K, Godin B, Oborn CJ, Alexander JF, Liu X, Fidler IJ, Ferrari M (2013) Porous silicon nanocarriers for dual targeting tumor associated endothelial cells and macrophages in stroma of orthotopic human pancreatic cancers. Cancer Lett 334(2):319-327. doi:10.1016/j. canlet.2012.09.001
-
(2013)
Cancer Lett
, vol.334
, Issue.2
, pp. 319-327
-
-
Yokoi, K.1
Godin, B.2
Oborn, C.J.3
Alexander, J.F.4
Liu, X.5
Fidler, I.J.6
Ferrari, M.7
-
46
-
-
84875217448
-
Fibroblast-mediated drug resistance in cancer
-
Paraiso KH, Smalley KS (2013) Fibroblast-mediated drug resistance in cancer. Biochem Pharmacol 85(8):1033-1041. doi:10.1016/j.bcp.2013.01.018
-
(2013)
Biochem Pharmacol
, vol.85
, Issue.8
, pp. 1033-1041
-
-
Paraiso, K.H.1
Smalley, K.S.2
-
47
-
-
84902546715
-
Targeting tumor-associated macrophages with anti-CSF-1R antibody reveals a strategy for cancer therapy
-
Ries CH, Cannarile MA, Hoves S, Benz J, Wartha K, Runza V, Rey-Giraud F, Pradel LP, Feuerhake F, Klaman I, Jones T, Jucknischke U, Scheiblich S, Kaluza K, Gorr IH, Walz A, Abiraj K, Cassier PA, Sica A, Gomez-Roca C, de Visser KE, Italiano A, Le Tourneau C, Delord JP, Levitsky H, Blay JY, Ruttinger D (2014) Targeting tumor-associated macrophages with anti-CSF-1R antibody reveals a strategy for cancer therapy. Cancer Cell 25(6):846-859. doi:10.1016/j.ccr.2014.05.016
-
(2014)
Cancer Cell
, vol.25
, Issue.6
, pp. 846-859
-
-
Ries, C.H.1
Cannarile, M.A.2
Hoves, S.3
Benz, J.4
Wartha, K.5
Runza, V.6
Rey-Giraud, F.7
Pradel, L.P.8
Feuerhake, F.9
Klaman, I.10
Jones, T.11
Jucknischke, U.12
Scheiblich, S.13
Kaluza, K.14
Gorr, I.H.15
Walz, A.16
Abiraj, K.17
Cassier, P.A.18
Sica, A.19
Gomez-Roca, C.20
de Visser, K.E.21
Italiano, A.22
Le Tourneau, C.23
Delord, J.P.24
Levitsky, H.25
Blay, J.Y.26
Ruttinger, D.27
more..
-
48
-
-
84902469661
-
Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival
-
Ozdemir BC, Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A, Sharma P, Heidari P, Mahmood U, Chin L, Moses HL, Weaver VM, Maitra A, Allison JP, LeBleu VS, Kalluri R (2014) Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival. Cancer Cell 25(6):719-734. doi:10.1016/j. ccr.2014.04.005
-
(2014)
Cancer Cell
, vol.25
, Issue.6
, pp. 719-734
-
-
Ozdemir, B.C.1
Pentcheva-Hoang, T.2
Carstens, J.L.3
Zheng, X.4
Wu, C.C.5
Simpson, T.R.6
Laklai, H.7
Sugimoto, H.8
Kahlert, C.9
Novitskiy, S.V.10
De Jesus-Acosta, A.11
Sharma, P.12
Heidari, P.13
Mahmood, U.14
Chin, L.15
Moses, H.L.16
Weaver, V.M.17
Maitra, A.18
Allison, J.P.19
LeBleu, V.S.20
Kalluri, R.21
more..
-
49
-
-
84868633053
-
Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B
-
Sun Y, Campisi J, Higano C, Beer TM, Porter P, Coleman I, True L, Nelson PS (2012) Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B. Nat Med 18(9):1359-1368. doi:10.1038/nm.2890
-
(2012)
Nat Med
, vol.18
, Issue.9
, pp. 1359-1368
-
-
Sun, Y.1
Campisi, J.2
Higano, C.3
Beer, T.M.4
Porter, P.5
Coleman, I.6
True, L.7
Nelson, P.S.8
-
50
-
-
33745837774
-
Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake
-
Loeffler M, Kruger JA, Niethammer AG, Reisfeld RA (2006) Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake. J Clin Investig 116(7):1955-1962. doi:10.1172/JCI26532
-
(2006)
J Clin Investig
, vol.116
, Issue.7
, pp. 1955-1962
-
-
Loeffler, M.1
Kruger, J.A.2
Niethammer, A.G.3
Reisfeld, R.A.4
-
51
-
-
84888876456
-
Lipid-coated cisplatin nanoparticles induce neighboring effect and exhibit enhanced anticancer efficacy
-
Guo S, Wang Y, Miao L, Xu Z, Lin CM, Zhang Y, Huang L (2013) Lipid-coated cisplatin nanoparticles induce neighboring effect and exhibit enhanced anticancer efficacy. ACS Nano 7(11):9896-9904. doi:10.1021/nn403606m
-
(2013)
ACS Nano
, vol.7
, Issue.11
, pp. 9896-9904
-
-
Guo, S.1
Wang, Y.2
Miao, L.3
Xu, Z.4
Lin, C.M.5
Zhang, Y.6
Huang, L.7
-
52
-
-
84861343605
-
The tumor accumulation and therapeutic efficacy of doxorubicin carried in calcium phosphate-reinforced polymer nanoparticles
-
Min KH, Lee HJ, Kim K, Kwon IC, Jeong SY, Lee SC (2012) The tumor accumulation and therapeutic efficacy of doxorubicin carried in calcium phosphate-reinforced polymer nanoparticles. Biomaterials 33(23):5788-5797. doi:10.1016/j.biomaterials.2012.04.057
-
(2012)
Biomaterials
, vol.33
, Issue.23
, pp. 5788-5797
-
-
Min, K.H.1
Lee, H.J.2
Kim, K.3
Kwon, I.C.4
Jeong, S.Y.5
Lee, S.C.6
-
53
-
-
84897385973
-
Synergistic anti-tumor effects of combined gemcitabine and cisplatin nanoparticles in a stroma-rich bladder carcinoma model
-
Zhang J, Miao L, Guo S, Zhang Y, Zhang L, Satterlee A, Kim WY, Huang L (2014) Synergistic anti-tumor effects of combined gemcitabine and cisplatin nanoparticles in a stroma-rich bladder carcinoma model. J Controlled Release Off J Controlled Release Soc 182:90-96. doi:10.1016/j.jconrel.2014.03.016
-
(2014)
J Controlled Release Off J Controlled Release Soc
, vol.182
, pp. 90-96
-
-
Zhang, J.1
Miao, L.2
Guo, S.3
Zhang, Y.4
Zhang, L.5
Satterlee, A.6
Kim, W.Y.7
Huang, L.8
-
54
-
-
79961230399
-
Pericytes: Developmental, physiological, and pathological perspectives, problems, and promises
-
Armulik A, Genove G, Betsholtz C (2011) Pericytes: developmental, physiological, and pathological perspectives, problems, and promises. Dev Cell 21(2):193-215. doi:10.1016/j. devcel.2011.07.001
-
(2011)
Dev Cell
, vol.21
, Issue.2
, pp. 193-215
-
-
Armulik, A.1
Genove, G.2
Betsholtz, C.3
-
55
-
-
0022567611
-
The pericyte-a review
-
Sims DE (1986) The pericyte-a review. Tissue Cell 18(2):153-174
-
(1986)
Tissue Cell
, vol.18
, Issue.2
, pp. 153-174
-
-
Sims, D.E.1
-
56
-
-
0024786451
-
Ultrastructure of basement membranes
-
Inoue S (1989) Ultrastructure of basement membranes. Int Rev Cytol 117:57-98
-
(1989)
Int Rev Cytol
, vol.117
, pp. 57-98
-
-
Inoue, S.1
-
57
-
-
84905977650
-
Capillary-wall collagen as a biophysical marker of nanotherapeutic permeability into the tumor microenvironment
-
Yokoi K, Kojic M, Milosevic M, Tanei T, Ferrari M, Ziemys A (2014) Capillary-wall collagen as a biophysical marker of nanotherapeutic permeability into the tumor microenvironment. Cancer Res 74(16):4239-4246. doi:10.1158/0008-5472.CAN-13-3494
-
(2014)
Cancer Res
, vol.74
, Issue.16
, pp. 4239-4246
-
-
Yokoi, K.1
Kojic, M.2
Milosevic, M.3
Tanei, T.4
Ferrari, M.5
Ziemys, A.6
-
58
-
-
79959963318
-
Extravasation of polymeric nanomedicines across tumor vasculature
-
Danquah MK, Zhang XA, Mahato RI (2011) Extravasation of polymeric nanomedicines across tumor vasculature. Adv Drug Deliv Rev 63(8):623-639. doi:10.1016/j.addr.2010.11. 005
-
(2011)
Adv Drug Deliv Rev
, vol.63
, Issue.8
, pp. 623-639
-
-
Danquah, M.K.1
Zhang, X.A.2
Mahato, R.I.3
-
59
-
-
0033093483
-
Endothelial gaps as sites for plasma leakage in inflammation
-
McDonald DM, Thurston G, Baluk P (1999) Endothelial gaps as sites for plasma leakage in inflammation. Microcirculation 6(1):7-22
-
(1999)
Microcirculation
, vol.6
, Issue.1
, pp. 7-22
-
-
McDonald, D.M.1
Thurston, G.2
Baluk, P.3
-
60
-
-
0023600043
-
Basement membrane structure in situ: Evidence for lateral associations in the type IV collagen network
-
Yurchenco PD, Ruben GC (1987) Basement membrane structure in situ: evidence for lateral associations in the type IV collagen network. J Cell Biol 105(6 Pt 1):2559-2568
-
(1987)
J Cell Biol
, vol.105
, Issue.6
, pp. 2559-2568
-
-
Yurchenco, P.D.1
Ruben, G.C.2
-
61
-
-
84866764636
-
Peptide-modified liposomes for selective targeting of bombesin receptors overexpressed by cancer cells: A potential theranostic agent
-
Accardo A, Salsano G, Morisco A, Aurilio M, Parisi A, Maione F, Cicala C, Tesauro D, Aloj L, De Rosa G, Morelli G (2012) Peptide-modified liposomes for selective targeting of bombesin receptors overexpressed by cancer cells: a potential theranostic agent. Int J Nanomed 7:2007-2017. doi:10.2147/IJN.S29242
-
(2012)
Int J Nanomed
, vol.7
, pp. 2007-2017
-
-
Accardo, A.1
Salsano, G.2
Morisco, A.3
Aurilio, M.4
Parisi, A.5
Maione, F.6
Cicala, C.7
Tesauro, D.8
Aloj, L.9
De Rosa, G.10
Morelli, G.11
-
62
-
-
0037072555
-
Folate-mediated delivery of macromolecular anticancer therapeutic agents
-
Lu Y, Low PS (2002) Folate-mediated delivery of macromolecular anticancer therapeutic agents. Adv Drug Deliv Rev 54(5):675-693
-
(2002)
Adv Drug Deliv Rev
, vol.54
, Issue.5
, pp. 675-693
-
-
Lu, Y.1
Low, P.S.2
-
63
-
-
42349094203
-
Nanoparticles in medicine: Therapeutic applications and developments
-
Zhang L, Gu FX, Chan JM, Wang AZ, Langer RS, Farokhzad OC (2008) Nanoparticles in medicine: therapeutic applications and developments. Clin Pharmacol Ther 83(5):761-769. doi:10.1038/sj.clpt.6100400
-
(2008)
Clin Pharmacol Ther
, vol.83
, Issue.5
, pp. 761-769
-
-
Zhang, L.1
Gu, F.X.2
Chan, J.M.3
Wang, A.Z.4
Langer, R.S.5
Farokhzad, O.C.6
-
64
-
-
84905101306
-
Five year results of the first US FDA-approved hip resurfacing device
-
Su EP, Housman LR, Masonis JL, Noble JW Jr, Engh CA (2014) Five year results of the first US FDA-approved hip resurfacing device. J Arthroplast 29(8):1571-1575. doi:10.1016/j. arth.2014.03.021
-
(2014)
J Arthroplast
, vol.29
, Issue.8
, pp. 1571-1575
-
-
Su, E.P.1
Housman, L.R.2
Masonis, J.L.3
Noble, J.W.4
Engh, C.A.5
-
65
-
-
84879977345
-
Using functional nanomaterials to target and regulate the tumor microenvironment: Diagnostic and therapeutic applications
-
Tianjiao Ji YZ, Ding Y, Nie G (2013) Using functional nanomaterials to target and regulate the tumor microenvironment: diagnostic and therapeutic applications. Adv Mater 25 (26):3508-3525. doi:10.1002/adma.201300299
-
(2013)
Adv Mater
, vol.25
, Issue.26
, pp. 3508-3525
-
-
Tianjiao Ji, Y.Z.1
Ding, Y.2
Nie, G.3
-
66
-
-
0028470454
-
Barriers to drug delivery in solid tumors
-
Jain RK (1994) Barriers to drug delivery in solid tumors. Sci Am 271(1):58-65
-
(1994)
Sci Am
, vol.271
, Issue.1
, pp. 58-65
-
-
Jain, R.K.1
-
67
-
-
0025334830
-
Interstitial pressure gradients in tissue-isolated and subcutaneous tumors: Implications for therapy
-
Boucher Y, Baxter LT, Jain RK (1990) Interstitial pressure gradients in tissue-isolated and subcutaneous tumors: implications for therapy. Cancer Res 50(15):4478-4484
-
(1990)
Cancer Res
, vol.50
, Issue.15
, pp. 4478-4484
-
-
Boucher, Y.1
Baxter, L.T.2
Jain, R.K.3
-
68
-
-
84857556564
-
Lymphatic and interstitial flow in the tumour microenvironment: Linking mechanobiology with immunity
-
Swartz MA, Lund AW (2012) Lymphatic and interstitial flow in the tumour microenvironment: linking mechanobiology with immunity. Nat Rev Cancer 12(3):210-219. doi:10.1038/nrc3186
-
(2012)
Nat Rev Cancer
, vol.12
, Issue.3
, pp. 210-219
-
-
Swartz, M.A.1
Lund, A.W.2
-
69
-
-
0026786660
-
Microvascular pressure is the principal driving force for interstitial hypertension in solid tumors: Implications for vascular collapse
-
Boucher Y, Jain RK (1992) Microvascular pressure is the principal driving force for interstitial hypertension in solid tumors: implications for vascular collapse. Cancer Res 52 (18):5110-5114
-
(1992)
Cancer Res
, vol.52
, Issue.18
, pp. 5110-5114
-
-
Boucher, Y.1
Jain, R.K.2
-
70
-
-
1542320497
-
Pathology: Cancer cells compress intratumour vessels
-
Padera TP, Stoll BR, Tooredman JB, Capen D, di Tomaso E, Jain RK (2004) Pathology: cancer cells compress intratumour vessels. Nature 427(6976):695. doi:10.1038/427695a
-
(2004)
Nature
, vol.427
, Issue.6976
, pp. 695
-
-
Padera, T.P.1
Stoll, B.R.2
Tooredman, J.B.3
Capen, D.4
di Tomaso, E.5
Jain, R.K.6
-
71
-
-
11844254414
-
Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
-
Jain RK (2005) Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 307(5706):58-62. doi:10.1126/science.1104819
-
(2005)
Science
, vol.307
, Issue.5706
, pp. 58-62
-
-
Jain, R.K.1
-
72
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D, Weinberg RA (2011) Hallmarks of cancer: the next generation. Cell 144 (5):646-674. doi:10.1016/j.cell.2011.02.013
-
(2011)
Cell
, vol.144
, Issue.5
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
73
-
-
84906043943
-
Nanotechnology and tumor microcirculation
-
Kano MR (2014) Nanotechnology and tumor microcirculation. Adv Drug Deliv Rev 74C:2-11. doi:10.1016/j.addr.2013.08.010
-
(2014)
Adv Drug Deliv Rev
, vol.74 C
, pp. 2-11
-
-
Kano, M.R.1
-
74
-
-
0042125242
-
Endothelial PDGF-B retention is required for proper investment of pericytes in the microvessel wall
-
Lindblom P, Gerhardt H, Liebner S, Abramsson A, Enge M, Hellstrom M, Backstrom G, Fredriksson S, Landegren U, Nystrom HC, Bergstrom G, Dejana E, Ostman A, Lindahl P, Betsholtz C (2003) Endothelial PDGF-B retention is required for proper investment of pericytes in the microvessel wall. Genes Dev 17(15):1835-1840. doi:10.1101/gad.266803
-
(2003)
Genes Dev
, vol.17
, Issue.15
, pp. 1835-1840
-
-
Lindblom, P.1
Gerhardt, H.2
Liebner, S.3
Abramsson, A.4
Enge, M.5
Hellstrom, M.6
Backstrom, G.7
Fredriksson, S.8
Landegren, U.9
Nystrom, H.C.10
Bergstrom, G.11
Dejana, E.12
Ostman, A.13
Lindahl, P.14
Betsholtz, C.15
-
75
-
-
68049140803
-
Overexpression of platelet-derived growth factor-BB increases tumor pericyte content via stromal-derived factor-1alpha/CXCR4 axis
-
Song N, Huang Y, Shi H, Yuan S, Ding Y, Song X, Fu Y, Luo Y (2009) Overexpression of platelet-derived growth factor-BB increases tumor pericyte content via stromal-derived factor-1alpha/CXCR4 axis. Cancer Res 69(15):6057-6064. doi:10.1158/0008-5472.CAN- 08-2007
-
(2009)
Cancer Res
, vol.69
, Issue.15
, pp. 6057-6064
-
-
Song, N.1
Huang, Y.2
Shi, H.3
Yuan, S.4
Ding, Y.5
Song, X.6
Fu, Y.7
Luo, Y.8
-
76
-
-
82955240979
-
Heparin-binding EGF-like growth factor protects pericytes from injury
-
Yu X, Radulescu A, Chen CL, James IO, Besner GE (2012) Heparin-binding EGF-like growth factor protects pericytes from injury. J Surg Res 172(1):165-176. doi:10.1016/j.jss. 2010.07.058
-
(2012)
J Surg Res
, vol.172
, Issue.1
, pp. 165-176
-
-
Yu, X.1
Radulescu, A.2
Chen, C.L.3
James, I.O.4
Besner, G.E.5
-
77
-
-
0345798150
-
Endothelial and nonendothelial sources of PDGF-B regulate pericyte recruitment and influence vascular pattern formation in tumors
-
Abramsson A, Lindblom P, Betsholtz C (2003) Endothelial and nonendothelial sources of PDGF-B regulate pericyte recruitment and influence vascular pattern formation in tumors. J Clin Investig 112(8):1142-1151. doi:10.1172/JCI18549
-
(2003)
J Clin Investig
, vol.112
, Issue.8
, pp. 1142-1151
-
-
Abramsson, A.1
Lindblom, P.2
Betsholtz, C.3
-
78
-
-
57649135172
-
A role for VEGF as a negative regulator of pericyte function and vessel maturation
-
Greenberg JI, Shields DJ, Barillas SG, Acevedo LM, Murphy E, Huang J, Scheppke L, Stockmann C, Johnson RS, Angle N, Cheresh DA (2008) A role for VEGF as a negative regulator of pericyte function and vessel maturation. Nature 456(7223):809-813. doi:10. 1038/nature07424
-
(2008)
Nature
, vol.456
, Issue.7223
, pp. 809-813
-
-
Greenberg, J.I.1
Shields, D.J.2
Barillas, S.G.3
Acevedo, L.M.4
Murphy, E.5
Huang, J.6
Scheppke, L.7
Stockmann, C.8
Johnson, R.S.9
Angle, N.10
Cheresh, D.A.11
-
79
-
-
16544382996
-
Platelet-derived growth factor production by B16 melanoma cells leads to increased pericyte abundance in tumors and an associated increase in tumor growth rate
-
Furuhashi M, Sjoblom T, Abramsson A, Ellingsen J, Micke P, Li H, Bergsten-Folestad E, Eriksson U, Heuchel R, Betsholtz C, Heldin CH, Ostman A (2004) Platelet-derived growth factor production by B16 melanoma cells leads to increased pericyte abundance in tumors and an associated increase in tumor growth rate. Cancer Res 64(8):2725-2733
-
(2004)
Cancer Res
, vol.64
, Issue.8
, pp. 2725-2733
-
-
Furuhashi, M.1
Sjoblom, T.2
Abramsson, A.3
Ellingsen, J.4
Micke, P.5
Li, H.6
Bergsten-Folestad, E.7
Eriksson, U.8
Heuchel, R.9
Betsholtz, C.10
Heldin, C.H.11
Ostman, A.12
-
80
-
-
84880287596
-
Tumour PDGF-BB expression levels determine dual effects of anti-PDGF drugs on vascular remodelling and metastasis
-
Hosaka K, Yang Y, Seki T, Nakamura M, Andersson P, Rouhi P, Yang X, Jensen L, Lim S, Feng N, Xue Y, Li X, Larsson O, Ohhashi T, Cao Y (2013) Tumour PDGF-BB expression levels determine dual effects of anti-PDGF drugs on vascular remodelling and metastasis. Nat Commun 4:2129. doi:10.1038/ncomms3129
-
(2013)
Nat Commun
, vol.4
, pp. 2129
-
-
Hosaka, K.1
Yang, Y.2
Seki, T.3
Nakamura, M.4
Andersson, P.5
Rouhi, P.6
Yang, X.7
Jensen, L.8
Lim, S.9
Feng, N.10
Xue, Y.11
Li, X.12
Larsson, O.13
Ohhashi, T.14
Cao, Y.15
-
81
-
-
84861205310
-
Pericyte-coverage of human tumor vasculature and nanoparticle permeability
-
Zhang L, Nishihara H, Kano MR (2012) Pericyte-coverage of human tumor vasculature and nanoparticle permeability. Biol Pharm Bull 35(5):761-766
-
(2012)
Biol Pharm Bull
, vol.35
, Issue.5
, pp. 761-766
-
-
Zhang, L.1
Nishihara, H.2
Kano, M.R.3
-
82
-
-
58149284060
-
Comparison of the effects of the kinase inhibitors imatinib, sorafenib, and transforming growth factor-beta receptor inhibitor on extravasation of nanoparticles from neovasculature
-
Kano MR, Komuta Y, Iwata C, Oka M, Shirai YT, Morishita Y, Ouchi Y, Kataoka K, Miyazono K (2009) Comparison of the effects of the kinase inhibitors imatinib, sorafenib, and transforming growth factor-beta receptor inhibitor on extravasation of nanoparticles from neovasculature. Cancer Sci 100(1):173-180. doi:10.1111/j.1349-7006.2008.01003.x
-
(2009)
Cancer Sci
, vol.100
, Issue.1
, pp. 173-180
-
-
Kano, M.R.1
Komuta, Y.2
Iwata, C.3
Oka, M.4
Shirai, Y.T.5
Morishita, Y.6
Ouchi, Y.7
Kataoka, K.8
Miyazono, K.9
-
83
-
-
33847635618
-
Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-beta signaling
-
Kano MR, Bae Y, Iwata C, Morishita Y, Yashiro M, Oka M, Fujii T, Komuro A, Kiyono K, Kaminishi M, Hirakawa K, Ouchi Y, Nishiyama N, Kataoka K, Miyazono K (2007) Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-beta signaling. Proc Natl Acad Sci USA 104(9):3460-3465. doi:10.1073/ pnas.0611660104
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.9
, pp. 3460-3465
-
-
Kano, M.R.1
Bae, Y.2
Iwata, C.3
Morishita, Y.4
Yashiro, M.5
Oka, M.6
Fujii, T.7
Komuro, A.8
Kiyono, K.9
Kaminishi, M.10
Hirakawa, K.11
Ouchi, Y.12
Nishiyama, N.13
Kataoka, K.14
Miyazono, K.15
-
84
-
-
84867362497
-
TGF-beta blockade improves the distribution and efficacy of therapeutics in breast carcinoma by normalizing the tumor stroma
-
Liu J, Liao S, Diop-Frimpong B, Chen W, Goel S, Naxerova K, Ancukiewicz M, Boucher Y, Jain RK, Xu L (2012) TGF-beta blockade improves the distribution and efficacy of therapeutics in breast carcinoma by normalizing the tumor stroma. Proc Natl Acad Sci USA 109(41):16618-16623. doi:10.1073/pnas.1117610109
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.41
, pp. 16618-16623
-
-
Liu, J.1
Liao, S.2
Diop-Frimpong, B.3
Chen, W.4
Goel, S.5
Naxerova, K.6
Ancukiewicz, M.7
Boucher, Y.8
Jain, R.K.9
Xu, L.10
-
85
-
-
83555166219
-
Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size
-
Cabral H, Matsumoto Y, Mizuno K, Chen Q, Murakami M, Kimura M, Terada Y, Kano MR, Miyazono K, Uesaka M, Nishiyama N, Kataoka K (2011) Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size. Nat Nanotechnol 6 (12):815-823. doi:10.1038/nnano.2011.166
-
(2011)
Nat Nanotechnol
, vol.6
, Issue.12
, pp. 815-823
-
-
Cabral, H.1
Matsumoto, Y.2
Mizuno, K.3
Chen, Q.4
Murakami, M.5
Kimura, M.6
Terada, Y.7
Kano, M.R.8
Miyazono, K.9
Uesaka, M.10
Nishiyama, N.11
Kataoka, K.12
-
86
-
-
84888868397
-
Two-wave nanotherapy to target the stroma and optimize gemcitabine delivery to a human pancreatic cancer model in mice
-
Meng H, Zhao Y, Dong J, Xue M, Lin YS, Ji Z, Mai WX, Zhang H, Chang CH, Brinker CJ, Zink JI, Nel AE (2013) Two-wave nanotherapy to target the stroma and optimize gemcitabine delivery to a human pancreatic cancer model in mice. ACS Nano 7(11):10048-10065. doi:10.1021/nn404083m
-
(2013)
ACS Nano
, vol.7
, Issue.11
, pp. 10048-10065
-
-
Meng, H.1
Zhao, Y.2
Dong, J.3
Xue, M.4
Lin, Y.S.5
Ji, Z.6
Mai, W.X.7
Zhang, H.8
Chang, C.H.9
Brinker, C.J.10
Zink, J.I.11
Nel, A.E.12
-
87
-
-
70649115375
-
Increase in tumour permeability following TGF-beta type I receptorinhibitor treatment observed by dynamic contrast-enhanced MRI
-
Minowa T, Kawano K, Kuribayashi H, Shiraishi K, Sugino T, Hattori Y, Yokoyama M, Maitani Y (2009) Increase in tumour permeability following TGF-beta type I receptorinhibitor treatment observed by dynamic contrast-enhanced MRI. Br J Cancer 101(11):1884-1890. doi:10.1038/sj.bjc.6605367
-
(2009)
Br J Cancer
, vol.101
, Issue.11
, pp. 1884-1890
-
-
Minowa, T.1
Kawano, K.2
Kuribayashi, H.3
Shiraishi, K.4
Sugino, T.5
Hattori, Y.6
Yokoyama, M.7
Maitani, Y.8
-
88
-
-
70449719188
-
Enhanced magnetic resonance imaging of experimental pancreatic tumor in vivo by block copolymer-coated magnetite nanoparticles with TGF-beta inhibitor
-
Kumagai M, Kano MR, Morishita Y, Ota M, Imai Y, Nishiyama N, Sekino M, Ueno S, Miyazono K, Kataoka K (2009) Enhanced magnetic resonance imaging of experimental pancreatic tumor in vivo by block copolymer-coated magnetite nanoparticles with TGF-beta inhibitor. J Controlled Release Off J Controlled Release Soc 140(3):306-311. doi:10.1016/j. jconrel.2009.06.002
-
(2009)
J Controlled Release Off J Controlled Release Soc
, vol.140
, Issue.3
, pp. 306-311
-
-
Kumagai, M.1
Kano, M.R.2
Morishita, Y.3
Ota, M.4
Imai, Y.5
Nishiyama, N.6
Sekino, M.7
Ueno, S.8
Miyazono, K.9
Kataoka, K.10
-
89
-
-
33749441325
-
Rapid vascular regrowth in tumors after reversal of VEGF inhibition
-
Mancuso MR, Davis R, Norberg SM, O'Brien S, Sennino B, Nakahara T, Yao VJ, Inai T, Brooks P, Freimark B, Shalinsky DR, Hu-Lowe DD, McDonald DM (2006) Rapid vascular regrowth in tumors after reversal of VEGF inhibition. J Clin Investig 116(10):2610-2621. doi:10.1172/JCI24612
-
(2006)
J Clin Investig
, vol.116
, Issue.10
, pp. 2610-2621
-
-
Mancuso, M.R.1
Davis, R.2
Norberg, S.M.3
O'Brien, S.4
Sennino, B.5
Nakahara, T.6
Yao, V.J.7
Inai, T.8
Brooks, P.9
Freimark, B.10
Shalinsky, D.R.11
Hu-Lowe, D.D.12
McDonald, D.M.13
-
90
-
-
84863655863
-
Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner
-
Chauhan VP, Stylianopoulos T, Martin JD, Popovic Z, Chen O, Kamoun WS, Bawendi MG, Fukumura D, Jain RK (2012) Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner. Nat Nanotechnol 7(6):383-388. doi:10.1038/ nnano.2012.45
-
(2012)
Nat Nanotechnol
, vol.7
, Issue.6
, pp. 383-388
-
-
Chauhan, V.P.1
Stylianopoulos, T.2
Martin, J.D.3
Popovic, Z.4
Chen, O.5
Kamoun, W.S.6
Bawendi, M.G.7
Fukumura, D.8
Jain, R.K.9
-
91
-
-
80054997801
-
New facets of matrix metalloproteinases MMP-2 and MMP-9 as cell surface transducers: Outside-in signaling and relationship to tumor progression
-
Bauvois B (2012) New facets of matrix metalloproteinases MMP-2 and MMP-9 as cell surface transducers: outside-in signaling and relationship to tumor progression. Biochim Biophys Acta 1825(1):29-36. doi:10.1016/j.bbcan.2011.10.001
-
(2012)
Biochim Biophys Acta
, vol.1825
, Issue.1
, pp. 29-36
-
-
Bauvois, B.1
-
92
-
-
84884545390
-
Role of collagen matrix in tumor angiogenesis and glioblastoma multiforme progression
-
Mammoto T, Jiang A, Jiang E, Panigrahy D, Kieran MW, Mammoto A (2013) Role of collagen matrix in tumor angiogenesis and glioblastoma multiforme progression. Am J Pathol 183(4):1293-1305. doi:10.1016/j.ajpath.2013.06.026
-
(2013)
Am J Pathol
, vol.183
, Issue.4
, pp. 1293-1305
-
-
Mammoto, T.1
Jiang, A.2
Jiang, E.3
Panigrahy, D.4
Kieran, M.W.5
Mammoto, A.6
-
93
-
-
78649315943
-
To exploit the tumor microenvironment: Passive and active tumor targeting of nanocarriers for anti-cancer drug delivery
-
Danhier F, Feron O, Preat V (2010) To exploit the tumor microenvironment: passive and active tumor targeting of nanocarriers for anti-cancer drug delivery. J Controlled Release Off J Controlled Release Soc 148(2):135-146. doi:10.1016/j.jconrel.2010.08.027
-
(2010)
J Controlled Release Off J Controlled Release Soc
, vol.148
, Issue.2
, pp. 135-146
-
-
Danhier, F.1
Feron, O.2
Preat, V.3
-
94
-
-
84876993950
-
Normalizing tumor microenvironment to treat cancer: Bench to bedside to biomarkers
-
Jain RK (2013) Normalizing tumor microenvironment to treat cancer: bench to bedside to biomarkers. J Clin Oncol Off J Am Soc Clin Oncol 31(17):2205-2218. doi:10.1200/JCO. 2012.46.3653
-
(2013)
J Clin Oncol Off J Am Soc Clin Oncol
, vol.31
, Issue.17
, pp. 2205-2218
-
-
Jain, R.K.1
-
95
-
-
84903315154
-
Microenvironment: An exercise in restraint
-
Alderton GK (2014) Microenvironment: an exercise in restraint. Nat Rev Cancer 14(7):449. doi:10.1038/nrc3769
-
(2014)
Nat Rev Cancer
, vol.14
, Issue.7
, pp. 449
-
-
Alderton, G.K.1
-
96
-
-
79952594233
-
Losartan inhibits collagen I synthesis and improves the distribution and efficacy of nanotherapeutics in tumors
-
Diop-Frimpong B, Chauhan VP, Krane S, Boucher Y, Jain RK (2011) Losartan inhibits collagen I synthesis and improves the distribution and efficacy of nanotherapeutics in tumors. Proc Natl Acad Sci USA 108 (7):2909-2914. doi:10.1073/pnas.1018892108
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.7
, pp. 2909-2914
-
-
Diop-Frimpong, B.1
Chauhan, V.P.2
Krane, S.3
Boucher, Y.4
Jain, R.K.5
-
97
-
-
34249316871
-
Relaxin-expressing, fiber chimeric oncolytic adenovirus prolongs survival of tumor-bearing mice
-
Ganesh S, Gonzalez Edick M, Idamakanti N, Abramova M, Vanroey M, Robinson M, Yun CO, Jooss K (2007) Relaxin-expressing, fiber chimeric oncolytic adenovirus prolongs survival of tumor-bearing mice. Cancer Res 67(9):4399-4407. doi:10.1158/0008-5472. CAN-06-4260
-
(2007)
Cancer Res
, vol.67
, Issue.9
, pp. 4399-4407
-
-
Ganesh, S.1
Gonzalez Edick, M.2
Idamakanti, N.3
Abramova, M.4
Vanroey, M.5
Robinson, M.6
Yun, C.O.7
Jooss, K.8
-
98
-
-
33645066093
-
Degradation of fibrillar collagen in a human melanoma xenograft improves the efficacy of an oncolytic herpes simplex virus vector
-
McKee TD, Grandi P, Mok W, Alexandrakis G, Insin N, Zimmer JP, Bawendi MG, Boucher Y, Breakefield XO, Jain RK (2006) Degradation of fibrillar collagen in a human melanoma xenograft improves the efficacy of an oncolytic herpes simplex virus vector. Cancer Res 66 (5):2509-2513. doi:10.1158/0008-5472.CAN-05-2242
-
(2006)
Cancer Res
, vol.66
, Issue.5
, pp. 2509-2513
-
-
McKee, T.D.1
Grandi, P.2
Mok, W.3
Alexandrakis, G.4
Insin, N.5
Zimmer, J.P.6
Bawendi, M.G.7
Boucher, Y.8
Breakefield, X.O.9
Jain, R.K.10
-
99
-
-
78649270513
-
Diffusion anisotropy in collagen gels and tumors: The effect of fiber network orientation
-
Stylianopoulos T, Diop-Frimpong B, Munn LL, Jain RK (2010) Diffusion anisotropy in collagen gels and tumors: the effect of fiber network orientation. Biophys J 99(10):3119-3128. doi:10.1016/j.bpj.2010.08.065
-
(2010)
Biophys J
, vol.99
, Issue.10
, pp. 3119-3128
-
-
Stylianopoulos, T.1
Diop-Frimpong, B.2
Munn, L.L.3
Jain, R.K.4
-
100
-
-
84862301989
-
Inhibition of mammary tumor growth using lysyl oxidasetargeting nanoparticles to modify extracellular matrix
-
Kanapathipillai M, Mammoto A, Mammoto T, Kang JH, Jiang E, Ghosh K, Korin N, Gibbs A, Mannix R, Ingber DE (2012) Inhibition of mammary tumor growth using lysyl oxidasetargeting nanoparticles to modify extracellular matrix. Nano Lett 12(6):3213-3217. doi:10. 1021/nl301206p
-
(2012)
Nano Lett
, vol.12
, Issue.6
, pp. 3213-3217
-
-
Kanapathipillai, M.1
Mammoto, A.2
Mammoto, T.3
Kang, J.H.4
Jiang, E.5
Ghosh, K.6
Korin, N.7
Gibbs, A.8
Mannix, R.9
Ingber, D.E.10
-
101
-
-
84871157346
-
Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer
-
Jacobetz MA, Chan DS, Neesse A, Bapiro TE, Cook N, Frese KK, Feig C, Nakagawa T, Caldwell ME, Zecchini HI, Lolkema MP, Jiang P, Kultti A, Thompson CB, Maneval DC, Jodrell DI, Frost GI, Shepard HM, Skepper JN, Tuveson DA (2013) Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer. Gut 62(1):112-120. doi:10.1136/gutjnl-2012-302529
-
(2013)
Gut
, vol.62
, Issue.1
, pp. 112-120
-
-
Jacobetz, M.A.1
Chan, D.S.2
Neesse, A.3
Bapiro, T.E.4
Cook, N.5
Frese, K.K.6
Feig, C.7
Nakagawa, T.8
Caldwell, M.E.9
Zecchini, H.I.10
Lolkema, M.P.11
Jiang, P.12
Kultti, A.13
Thompson, C.B.14
Maneval, D.C.15
Jodrell, D.I.16
Frost, G.I.17
Shepard, H.M.18
Skepper, J.N.19
Tuveson, D.A.20
more..
-
102
-
-
84872611820
-
Hyaluronan, fluid pressure, and stromal resistance in pancreas cancer
-
Provenzano PP, Hingorani SR (2013) Hyaluronan, fluid pressure, and stromal resistance in pancreas cancer. Br J Cancer 108(1):1-8. doi:10.1038/bjc.2012.569
-
(2013)
Br J Cancer
, vol.108
, Issue.1
, pp. 1-8
-
-
Provenzano, P.P.1
Hingorani, S.R.2
-
103
-
-
24144498662
-
Direct measurement of osmotic pressure of glycosaminoglycan solutions by membrane osmometry at room temperature
-
Chahine NO, Chen FH, Hung CT, Ateshian GA (2005) Direct measurement of osmotic pressure of glycosaminoglycan solutions by membrane osmometry at room temperature. Biophys J 89(3):1543-1550. doi:10.1529/biophysj.104.057315
-
(2005)
Biophys J
, vol.89
, Issue.3
, pp. 1543-1550
-
-
Chahine, N.O.1
Chen, F.H.2
Hung, C.T.3
Ateshian, G.A.4
-
104
-
-
67149143399
-
Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer
-
Olive KP, Jacobetz MA, Davidson CJ, Gopinathan A, McIntyre D, Honess D, Madhu B, Goldgraben MA, Caldwell ME, Allard D, Frese KK, Denicola G, Feig C, Combs C, Winter SP, Ireland-Zecchini H, Reichelt S, Howat WJ, Chang A, Dhara M, Wang L, Ruckert F, Grutzmann R, Pilarsky C, Izeradjene K, Hingorani SR, Huang P, Davies SE, Plunkett W, Egorin M, Hruban RH, Whitebread N, McGovern K, Adams J, Iacobuzio-Donahue C, Griffiths J, Tuveson DA (2009) Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer. Science 324(5933):1457-1461. doi:10. 1126/science.1171362
-
(2009)
Science
, vol.324
, Issue.5933
, pp. 1457-1461
-
-
Olive, K.P.1
Jacobetz, M.A.2
Davidson, C.J.3
Gopinathan, A.4
McIntyre, D.5
Honess, D.6
Madhu, B.7
Goldgraben, M.A.8
Caldwell, M.E.9
Allard, D.10
Frese, K.K.11
Denicola, G.12
Feig, C.13
Combs, C.14
Winter, S.P.15
Ireland-Zecchini, H.16
Reichelt, S.17
Howat, W.J.18
Chang, A.19
Dhara, M.20
Wang, L.21
Ruckert, F.22
Grutzmann, R.23
Pilarsky, C.24
Izeradjene, K.25
Hingorani, S.R.26
Huang, P.27
Davies, S.E.28
Plunkett, W.29
Egorin, M.30
Hruban, R.H.31
Whitebread, N.32
McGovern, K.33
Adams, J.34
Iacobuzio-Donahue, C.35
Griffiths, J.36
Tuveson, D.A.37
more..
-
105
-
-
0026715206
-
Hyaluronidase enhances the activity of adriamycin in breast cancer models in vitro and in vivo
-
Beckenlehner K, Bannke S, Spruss T, Bernhardt G, Schonenberg H, Schiess W (1992) Hyaluronidase enhances the activity of adriamycin in breast cancer models in vitro and in vivo. J Cancer Res Clin Oncol 118(8):591-596
-
(1992)
J Cancer Res Clin Oncol
, vol.118
, Issue.8
, pp. 591-596
-
-
Beckenlehner, K.1
Bannke, S.2
Spruss, T.3
Bernhardt, G.4
Schonenberg, H.5
Schiess, W.6
-
106
-
-
0032508620
-
Hyaluronidase reduces the interstitial fluid pressure in solid tumours in a non-linear concentration-dependent manner
-
Brekken C, de Lange Davies C (1998) Hyaluronidase reduces the interstitial fluid pressure in solid tumours in a non-linear concentration-dependent manner. Cancer Lett 131(1):65-70
-
(1998)
Cancer Lett
, vol.131
, Issue.1
, pp. 65-70
-
-
Brekken, C.1
de Lange Davies, C.2
-
107
-
-
79955828776
-
Stromal biology and therapy in pancreatic cancer
-
Neesse A, Michl P, Frese KK, Feig C, Cook N, Jacobetz MA, Lolkema MP, Buchholz M, Olive KP, Gress TM, Tuveson DA (2011) Stromal biology and therapy in pancreatic cancer. Gut 60(6):861-868. doi:10.1136/gut.2010.226092
-
(2011)
Gut
, vol.60
, Issue.6
, pp. 861-868
-
-
Neesse, A.1
Michl, P.2
Frese, K.K.3
Feig, C.4
Cook, N.5
Jacobetz, M.A.6
Lolkema, M.P.7
Buchholz, M.8
Olive, K.P.9
Gress, T.M.10
Tuveson, D.A.11
-
108
-
-
46149090133
-
In vivo diffusion of lactoferrin in brain extracellular space is regulated by interactions with heparan sulfate
-
Thorne RG, Lakkaraju A, Rodriguez-Boulan E, Nicholson C (2008) In vivo diffusion of lactoferrin in brain extracellular space is regulated by interactions with heparan sulfate. Proc Natl Acad Sci USA 105(24):8416-8421. doi:10.1073/pnas.0711345105
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.24
, pp. 8416-8421
-
-
Thorne, R.G.1
Lakkaraju, A.2
Rodriguez-Boulan, E.3
Nicholson, C.4
-
109
-
-
10444261212
-
Development of TGF-beta signalling inhibitors for cancer therapy
-
Yingling JM, Blanchard KL, Sawyer JS (2004) Development of TGF-beta signalling inhibitors for cancer therapy. Nat Rev Drug Discov 3(12):1011-1022. doi:10.1038/nrd1580
-
(2004)
Nat Rev Drug Discov
, vol.3
, Issue.12
, pp. 1011-1022
-
-
Yingling, J.M.1
Blanchard, K.L.2
Sawyer, J.S.3
-
110
-
-
0034306974
-
Anti-Vascular endothelial growth factor treatment augments tumor radiation response under normoxic or hypoxic conditions
-
Lee CG, Heijn M, di Tomaso E, Griffon-Etienne G, Ancukiewicz M, Koike C, Park KR, Ferrara N, Jain RK, Suit HD, Boucher Y (2000) Anti-Vascular endothelial growth factor treatment augments tumor radiation response under normoxic or hypoxic conditions. Cancer Res 60(19):5565-5570
-
(2000)
Cancer Res
, vol.60
, Issue.19
, pp. 5565-5570
-
-
Lee, C.G.1
Heijn, M.2
di Tomaso, E.3
Griffon-Etienne, G.4
Ancukiewicz, M.5
Koike, C.6
Park, K.R.7
Ferrara, N.8
Jain, R.K.9
Suit, H.D.10
Boucher, Y.11
-
111
-
-
11144354392
-
Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer
-
Willett CG, Boucher Y, di Tomaso E, Duda DG, Munn LL, Tong RT, Chung DC, Sahani DV, Kalva SP, Kozin SV, Mino M, Cohen KS, Scadden DT, Hartford AC, Fischman AJ, Clark JW, Ryan DP, Zhu AX, Blaszkowsky LS, Chen HX, Shellito PC, Lauwers GY, Jain RK (2004) Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer. Nat Med 10(2):145-147. doi:10.1038/nm988
-
(2004)
Nat Med
, vol.10
, Issue.2
, pp. 145-147
-
-
Willett, C.G.1
Boucher, Y.2
di Tomaso, E.3
Duda, D.G.4
Munn, L.L.5
Tong, R.T.6
Chung, D.C.7
Sahani, D.V.8
Kalva, S.P.9
Kozin, S.V.10
Mino, M.11
Cohen, K.S.12
Scadden, D.T.13
Hartford, A.C.14
Fischman, A.J.15
Clark, J.W.16
Ryan, D.P.17
Zhu, A.X.18
Blaszkowsky, L.S.19
Chen, H.X.20
Shellito, P.C.21
Lauwers, G.Y.22
Jain, R.K.23
more..
-
112
-
-
20644432867
-
Bevacizumab in combination with fluorouracil and leucovorin: An active regimen for first-line metastatic colorectal cancer
-
Hurwitz HI, Fehrenbacher L, Hainsworth JD, Heim W, Berlin J, Holmgren E, Hambleton J, Novotny WF, Kabbinavar F (2005) Bevacizumab in combination with fluorouracil and leucovorin: an active regimen for first-line metastatic colorectal cancer. J Clin Oncol Off J Am Soc Clin Oncol 23(15):3502-3508. doi:10.1200/JCO.2005.10.017
-
(2005)
J Clin Oncol Off J Am Soc Clin Oncol
, vol.23
, Issue.15
, pp. 3502-3508
-
-
Hurwitz, H.I.1
Fehrenbacher, L.2
Hainsworth, J.D.3
Heim, W.4
Berlin, J.5
Holmgren, E.6
Hambleton, J.7
Novotny, W.F.8
Kabbinavar, F.9
-
113
-
-
0034662609
-
Hyperthermia enables tumor-specific nanoparticle delivery: Effect of particle size
-
Kong G, Braun RD, Dewhirst MW (2000) Hyperthermia enables tumor-specific nanoparticle delivery: effect of particle size. Cancer Res 60(16):4440-4445
-
(2000)
Cancer Res
, vol.60
, Issue.16
, pp. 4440-4445
-
-
Kong, G.1
Braun, R.D.2
Dewhirst, M.W.3
-
114
-
-
47949117043
-
Radiotherapy enhancement with gold nanoparticles
-
Hainfeld JF, Dilmanian FA, Slatkin DN, Smilowitz HM (2008) Radiotherapy enhancement with gold nanoparticles. J Pharm Pharmacol 60(8):977-985. doi:10.1211/jpp.60.8.0005
-
(2008)
J Pharm Pharmacol
, vol.60
, Issue.8
, pp. 977-985
-
-
Hainfeld, J.F.1
Dilmanian, F.A.2
Slatkin, D.N.3
Smilowitz, H.M.4
-
115
-
-
36348930079
-
Matrix metalloproteinases-1 and -8 improve the distribution and efficacy of an oncolytic virus
-
Mok W, Boucher Y, Jain RK (2007) Matrix metalloproteinases-1 and -8 improve the distribution and efficacy of an oncolytic virus. Cancer Res 67(22):10664-10668. doi:10. 1158/0008-5472.CAN-07-3107
-
(2007)
Cancer Res
, vol.67
, Issue.22
, pp. 10664-10668
-
-
Mok, W.1
Boucher, Y.2
Jain, R.K.3
-
116
-
-
33644772618
-
Tumor vascular permeability, accumulation, and penetration of macromolecular drug carriers
-
Dreher MR, Liu W, Michelich CR, Dewhirst MW, Yuan F, Chilkoti A (2006) Tumor vascular permeability, accumulation, and penetration of macromolecular drug carriers. J Natl Cancer Inst 98(5):335-344. doi:10.1093/jnci/djj070
-
(2006)
J Natl Cancer Inst
, vol.98
, Issue.5
, pp. 335-344
-
-
Dreher, M.R.1
Liu, W.2
Michelich, C.R.3
Dewhirst, M.W.4
Yuan, F.5
Chilkoti, A.6
-
117
-
-
0036897324
-
Cationic charge determines the distribution of liposomes between the vascular and extravascular compartments of tumors
-
Campbell RB, Fukumura D, Brown EB, Mazzola LM, Izumi Y, Jain RK, Torchilin VP, Munn LL (2002) Cationic charge determines the distribution of liposomes between the vascular and extravascular compartments of tumors. Cancer Res 62(23):6831-6836
-
(2002)
Cancer Res
, vol.62
, Issue.23
, pp. 6831-6836
-
-
Campbell, R.B.1
Fukumura, D.2
Brown, E.B.3
Mazzola, L.M.4
Izumi, Y.5
Jain, R.K.6
Torchilin, V.P.7
Munn, L.L.8
-
118
-
-
77956562428
-
Diffusion of particles in the extracellular matrix: The effect of repulsive electrostatic interactions
-
Stylianopoulos T, Poh MZ, Insin N, Bawendi MG, Fukumura D, Munn LL, Jain RK (2010) Diffusion of particles in the extracellular matrix: the effect of repulsive electrostatic interactions. Biophys J 99(5):1342-1349. doi:10.1016/j.bpj.2010.06.016
-
(2010)
Biophys J
, vol.99
, Issue.5
, pp. 1342-1349
-
-
Stylianopoulos, T.1
Poh, M.Z.2
Insin, N.3
Bawendi, M.G.4
Fukumura, D.5
Munn, L.L.6
Jain, R.K.7
-
119
-
-
0032978690
-
Diffusion of macromolecules in agarose gels: Comparison of linear and globular configurations
-
Pluen A, Netti PA, Jain RK, Berk DA (1999) Diffusion of macromolecules in agarose gels: comparison of linear and globular configurations. Biophys J 77(1):542-552. doi:10.1016/ S0006-3495(99)76911-0
-
(1999)
Biophys J
, vol.77
, Issue.1
, pp. 542-552
-
-
Pluen, A.1
Netti, P.A.2
Jain, R.K.3
Berk, D.A.4
-
120
-
-
79952291790
-
Multistage nanoparticle delivery system for deep penetration into tumor tissue
-
Wong C, Stylianopoulos T, Cui J, Martin J, Chauhan VP, Jiang W, Popovic Z, Jain RK, Bawendi MG, Fukumura D (2011) Multistage nanoparticle delivery system for deep penetration into tumor tissue. Proc Natl Acad Sci USA 108(6):2426-2431. doi:10.1073/pnas. 1018382108
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.6
, pp. 2426-2431
-
-
Wong, C.1
Stylianopoulos, T.2
Cui, J.3
Martin, J.4
Chauhan, V.P.5
Jiang, W.6
Popovic, Z.7
Jain, R.K.8
Bawendi, M.G.9
Fukumura, D.10
-
121
-
-
79960478878
-
Evaluation of the tumor targeting of a FAPalpha-based doxorubicin prodrug
-
Huang S, Fang R, Xu J, Qiu S, Zhang H, Du J, Cai S (2011) Evaluation of the tumor targeting of a FAPalpha-based doxorubicin prodrug. J Drug Target 19(7):487-496. doi:10. 3109/1061186X.2010.511225
-
(2011)
J Drug Target
, vol.19
, Issue.7
, pp. 487-496
-
-
Huang, S.1
Fang, R.2
Xu, J.3
Qiu, S.4
Zhang, H.5
Du, J.6
Cai, S.7
-
122
-
-
38349169216
-
Fibroblast activation protein peptide substrates identified from human collagen I derived gelatin cleavage sites
-
Aggarwal S, Brennen WN, Kole TP, Schneider E, Topaloglu O, Yates M, Cotter RJ, Denmeade SR (2008) Fibroblast activation protein peptide substrates identified from human collagen I derived gelatin cleavage sites. Biochemistry 47(3):1076-1086. doi:10.1021/ bi701921b
-
(2008)
Biochemistry
, vol.47
, Issue.3
, pp. 1076-1086
-
-
Aggarwal, S.1
Brennen, W.N.2
Kole, T.P.3
Schneider, E.4
Topaloglu, O.5
Yates, M.6
Cotter, R.J.7
Denmeade, S.R.8
-
123
-
-
79953066932
-
A multifunctional envelope type nano device (MEND) for gene delivery to tumours based on the EPR effect: A strategy for overcoming the PEG dilemma
-
Hatakeyama H, Akita H, Harashima H (2011) A multifunctional envelope type nano device (MEND) for gene delivery to tumours based on the EPR effect: a strategy for overcoming the PEG dilemma. Adv Drug Deliv Rev 63(3):152-160. doi:10.1016/j.addr.2010.09.001
-
(2011)
Adv Drug Deliv Rev
, vol.63
, Issue.3
, pp. 152-160
-
-
Hatakeyama, H.1
Akita, H.2
Harashima, H.3
-
124
-
-
66849125864
-
Targeting the cancer stroma with a fibroblast activation protein-activated promelittin protoxin
-
LeBeau AM, Brennen WN, Aggarwal S, Denmeade SR (2009) Targeting the cancer stroma with a fibroblast activation protein-activated promelittin protoxin. Mol Cancer Ther 8 (5):1378-1386. doi:10.1158/1535-7163.MCT-08-1170
-
(2009)
Mol Cancer Ther
, vol.8
, Issue.5
, pp. 1378-1386
-
-
LeBeau, A.M.1
Brennen, W.N.2
Aggarwal, S.3
Denmeade, S.R.4
-
125
-
-
79957815663
-
pH-triggered drug-releasing magnetic nanoparticles for cancer therapy guided by molecular imaging by MRI
-
Lim EK, Huh YM, Yang J, Lee K, Suh JS, Haam S (2011) pH-triggered drug-releasing magnetic nanoparticles for cancer therapy guided by molecular imaging by MRI. Adv Mater 23(21):2436-2442. doi:10.1002/adma.201100351
-
(2011)
Adv Mater
, vol.23
, Issue.21
, pp. 2436-2442
-
-
Lim, E.K.1
Huh, Y.M.2
Yang, J.3
Lee, K.4
Suh, J.S.5
Haam, S.6
-
126
-
-
76749128372
-
pH-Sensitive degradable polymersomes for triggered release of anticancer drugs: A comparative study with micelles
-
Chen W, Meng F, Cheng R, Zhong Z (2010) pH-Sensitive degradable polymersomes for triggered release of anticancer drugs: a comparative study with micelles. J Controlled Release Off J Controlled Release Soc 142(1):40-46. doi:10.1016/j.jconrel.2009.09.023
-
(2010)
J Controlled Release Off J Controlled Release Soc
, vol.142
, Issue.1
, pp. 40-46
-
-
Chen, W.1
Meng, F.2
Cheng, R.3
Zhong, Z.4
-
127
-
-
84856204786
-
Drug release from electricfield- responsive nanoparticles
-
Ge J, Neofytou E, Cahill TJ 3rd, Beygui RE, Zare RN (2012) Drug release from electricfield- responsive nanoparticles. ACS Nano 6(1):227-233. doi:10.1021/nn203430m
-
(2012)
ACS Nano
, vol.6
, Issue.1
, pp. 227-233
-
-
Ge, J.1
Neofytou, E.2
Cahill, T.J.3
Beygui, R.E.4
Zare, R.N.5
-
128
-
-
84885190531
-
Magnetic field triggered drug release from polymersomes for cancer therapeutics
-
Oliveira H, Perez-Andres E, Thevenot J, Sandre O, Berra E, Lecommandoux S (2013) Magnetic field triggered drug release from polymersomes for cancer therapeutics. J Control Release Off J Controlled Release Soc 169(3):165-170. doi:10.1016/j.jconrel.2013.01.013
-
(2013)
J Control Release Off J Controlled Release Soc
, vol.169
, Issue.3
, pp. 165-170
-
-
Oliveira, H.1
Perez-Andres, E.2
Thevenot, J.3
Sandre, O.4
Berra, E.5
Lecommandoux, S.6
-
130
-
-
79961154863
-
Lightinduced release of DNA from gold nanoparticles: Nanoshells and nanorods
-
Huschka R, Zuloaga J, Knight MW, Brown LV, Nordlander P, Halas NJ (2011) Lightinduced release of DNA from gold nanoparticles: nanoshells and nanorods. J Am Chem Soc 133(31):12247-12255. doi:10.1021/ja204578e
-
(2011)
J Am Chem Soc
, vol.133
, Issue.31
, pp. 12247-12255
-
-
Huschka, R.1
Zuloaga, J.2
Knight, M.W.3
Brown, L.V.4
Nordlander, P.5
Halas, N.J.6
-
131
-
-
84868256944
-
Overcoming limitations in nanoparticle drug delivery: Triggered, intravascular release to improve drug penetration into tumors
-
Manzoor AA, Lindner LH, Landon CD, Park JY, Simnick AJ, Dreher MR, Das S, Hanna G, Park W, Chilkoti A, Koning GA, ten Hagen TL, Needham D, Dewhirst MW (2012) Overcoming limitations in nanoparticle drug delivery: triggered, intravascular release to improve drug penetration into tumors. Cancer Res 72(21):5566-5575. doi:10.1158/0008- 5472.CAN-12-1683
-
(2012)
Cancer Res
, vol.72
, Issue.21
, pp. 5566-5575
-
-
Manzoor, A.A.1
Lindner, L.H.2
Landon, C.D.3
Park, J.Y.4
Simnick, A.J.5
Dreher, M.R.6
Das, S.7
Hanna, G.8
Park, W.9
Chilkoti, A.10
Koning, G.A.11
ten Hagen, T.L.12
Needham, D.13
Dewhirst, M.W.14
-
132
-
-
33846985303
-
Low-density lipoprotein receptor-mediated endocytosis of PEGylated nanoparticles in rat brain endothelial cells
-
Kim HR, Gil S, Andrieux K, Nicolas V, Appel M, Chacun H, Desmaele D, Taran F, Georgin D, Couvreur P (2007) Low-density lipoprotein receptor-mediated endocytosis of PEGylated nanoparticles in rat brain endothelial cells. Cell Mol Life Sci CMLS 64(3):356-364. doi:10. 1007/s00018-007-6390-x
-
(2007)
Cell Mol Life Sci CMLS
, vol.64
, Issue.3
, pp. 356-364
-
-
Kim, H.R.1
Gil, S.2
Andrieux, K.3
Nicolas, V.4
Appel, M.5
Chacun, H.6
Desmaele, D.7
Taran, F.8
Georgin, D.9
Couvreur, P.10
-
133
-
-
80054795004
-
Targeted nanoparticle enhanced proapoptotic peptide as potential therapy for glioblastoma
-
Agemy L, Friedmann-Morvinski D, Kotamraju VR, Roth L, Sugahara KN, Girard OM, Mattrey RF, Verma IM, Ruoslahti E (2011) Targeted nanoparticle enhanced proapoptotic peptide as potential therapy for glioblastoma. Proc Natl Acad Sci USA 108(42):17450-17455. doi:10.1073/pnas.1114518108
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.42
, pp. 17450-17455
-
-
Agemy, L.1
Friedmann-Morvinski, D.2
Kotamraju, V.R.3
Roth, L.4
Sugahara, K.N.5
Girard, O.M.6
Mattrey, R.F.7
Verma, I.M.8
Ruoslahti, E.9
-
134
-
-
47949114921
-
Nanoparticle-mediated drug delivery to tumor vasculature suppresses metastasis
-
Murphy EA, Majeti BK, Barnes LA, Makale M, Weis SM, Lutu-Fuga K, Wrasidlo W, Cheresh DA (2008) Nanoparticle-mediated drug delivery to tumor vasculature suppresses metastasis. Proc Natl Acad Sci USA 105(27):9343-9348. doi:10.1073/pnas.0803728105
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.27
, pp. 9343-9348
-
-
Murphy, E.A.1
Majeti, B.K.2
Barnes, L.A.3
Makale, M.4
Weis, S.M.5
Lutu-Fuga, K.6
Wrasidlo, W.7
Cheresh, D.A.8
-
135
-
-
70749103751
-
Tissue-penetrating delivery of compounds and nanoparticles into tumors
-
Sugahara KN, Teesalu T, Karmali PP, Kotamraju VR, Agemy L, Girard OM, Hanahan D, Mattrey RF, Ruoslahti E (2009) Tissue-penetrating delivery of compounds and nanoparticles into tumors. Cancer Cell 16(6):510-520. doi:10.1016/j.ccr.2009.10.013
-
(2009)
Cancer Cell
, vol.16
, Issue.6
, pp. 510-520
-
-
Sugahara, K.N.1
Teesalu, T.2
Karmali, P.P.3
Kotamraju, V.R.4
Agemy, L.5
Girard, O.M.6
Hanahan, D.7
Mattrey, R.F.8
Ruoslahti, E.9
-
136
-
-
48749104610
-
PET/MRI dual-modality tumor imaging using arginine-glycine-aspartic (RGD)-conjugated radiolabeled iron oxide nanoparticles
-
Lee HY, Li Z, Chen K, Hsu AR, Xu C, Xie J, Sun S, Chen X (2008) PET/MRI dual-modality tumor imaging using arginine-glycine-aspartic (RGD)-conjugated radiolabeled iron oxide nanoparticles. J Nucl Med Off Publ Soc Nucl Med 49(8):1371-1379. doi:10.2967/jnumed. 108.051243
-
(2008)
J Nucl Med Off Publ Soc Nucl Med
, vol.49
, Issue.8
, pp. 1371-1379
-
-
Lee, H.Y.1
Li, Z.2
Chen, K.3
Hsu, A.R.4
Xu, C.5
Xie, J.6
Sun, S.7
Chen, X.8
-
137
-
-
0037817474
-
Physical characterization and macrophage cell uptake of mannan-coated nanoparticles
-
Cui Z, Hsu CH, Mumper RJ (2003) Physical characterization and macrophage cell uptake of mannan-coated nanoparticles. Drug Dev Ind Pharm 29(6):689-700. doi:10.1081/DDC- 120021318
-
(2003)
Drug Dev Ind Pharm
, vol.29
, Issue.6
, pp. 689-700
-
-
Cui, Z.1
Hsu, C.H.2
Mumper, R.J.3
-
138
-
-
84883567844
-
Targeting of tumor-associated macrophages made possible by PEG-sheddable, mannose-modified nanoparticles
-
Zhu S, Niu M, O'Mary H, Cui Z (2013) Targeting of tumor-associated macrophages made possible by PEG-sheddable, mannose-modified nanoparticles. Mol Pharm 10(9):3525-3530. doi:10.1021/mp400216r
-
(2013)
Mol Pharm
, vol.10
, Issue.9
, pp. 3525-3530
-
-
Zhu, S.1
Niu, M.2
O'Mary, H.3
Cui, Z.4
-
139
-
-
84893019819
-
Imaging macrophages with nanoparticles
-
Weissleder R, Nahrendorf M, Pittet MJ (2014) Imaging macrophages with nanoparticles. Nat Mater 13(2):125-138. doi:10.1038/nmat3780
-
(2014)
Nat Mater
, vol.13
, Issue.2
, pp. 125-138
-
-
Weissleder, R.1
Nahrendorf, M.2
Pittet, M.J.3
-
140
-
-
84862878560
-
Role of stromal myofibroblasts in invasive breast cancer: Stromal expression of alpha-smooth muscle actin correlates with worse clinical outcome
-
Yamashita M, Ogawa T, Zhang X, Hanamura N, Kashikura Y, Takamura M, Yoneda M, Shiraishi T (2012) Role of stromal myofibroblasts in invasive breast cancer: stromal expression of alpha-smooth muscle actin correlates with worse clinical outcome. Breast Cancer 19(2):170-176. doi:10.1007/s12282-010-0234-5
-
(2012)
Breast Cancer
, vol.19
, Issue.2
, pp. 170-176
-
-
Yamashita, M.1
Ogawa, T.2
Zhang, X.3
Hanamura, N.4
Kashikura, Y.5
Takamura, M.6
Yoneda, M.7
Shiraishi, T.8
-
142
-
-
84890281217
-
Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer
-
Feig C, Jones JO, Kraman M, Wells RJ, Deonarine A, Chan DS, Connell CM, Roberts EW, Zhao Q, Caballero OL, Teichmann SA, Janowitz T, Jodrell DI, Tuveson DA, Fearon DT (2013) Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer. Proc Natl Acad Sci USA 110 (50):20212-20217. doi:10.1073/pnas.1320318110
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, Issue.50
, pp. 20212-20217
-
-
Feig, C.1
Jones, J.O.2
Kraman, M.3
Wells, R.J.4
Deonarine, A.5
Chan, D.S.6
Connell, C.M.7
Roberts, E.W.8
Zhao, Q.9
Caballero, O.L.10
Teichmann, S.A.11
Janowitz, T.12
Jodrell, D.I.13
Tuveson, D.A.14
Fearon, D.T.15
-
143
-
-
84881427940
-
Docetaxel conjugate nanoparticles that target alpha-smooth muscle actin-expressing stromal cells suppress breast cancer metastasis
-
Murakami M, Ernsting MJ, Undzys E, Holwell N, Foltz WD, Li SD (2013) Docetaxel conjugate nanoparticles that target alpha-smooth muscle actin-expressing stromal cells suppress breast cancer metastasis. Cancer Res 73(15):4862-4871. doi:10.1158/0008-5472. CAN-13-0062
-
(2013)
Cancer Res
, vol.73
, Issue.15
, pp. 4862-4871
-
-
Murakami, M.1
Ernsting, M.J.2
Undzys, E.3
Holwell, N.4
Foltz, W.D.5
Li, S.D.6
-
144
-
-
84890002586
-
Unmodified drug used as a material to construct nanoparticles: Delivery of cisplatin for enhanced anti-cancer therapy
-
Guo S, Miao L, Wang Y, Huang L (2014) Unmodified drug used as a material to construct nanoparticles: delivery of cisplatin for enhanced anti-cancer therapy. J Control Release 174:137-142. doi:10.1016/j.jconrel.2013.11.019
-
(2014)
J Control Release
, vol.174
, pp. 137-142
-
-
Guo, S.1
Miao, L.2
Wang, Y.3
Huang, L.4
-
145
-
-
84857911904
-
Calcium phosphate nanoparticles with an asymmetric lipid bilayer coating for siRNA delivery to the tumor
-
Li J, Yang Y, Huang L (2012) Calcium phosphate nanoparticles with an asymmetric lipid bilayer coating for siRNA delivery to the tumor. J Control Release Off J Control Release Soc 158(1):108-114. doi:10.1016/j.jconrel.2011.10.020
-
(2012)
J Control Release Off J Control Release Soc
, vol.158
, Issue.1
, pp. 108-114
-
-
Li, J.1
Yang, Y.2
Huang, L.3
-
146
-
-
84901684242
-
Co-delivery of cisplatin and rapamycin for enhanced anticancer therapy through synergistic effects and microenvironment modulation
-
Guo S, Lin CM, Xu Z, Miao L, Wang Y, Huang L (2014) Co-delivery of cisplatin and rapamycin for enhanced anticancer therapy through synergistic effects and microenvironment modulation. ACS Nano 8(5):4996-5009. doi:10.1021/nn5010815
-
(2014)
ACS Nano
, vol.8
, Issue.5
, pp. 4996-5009
-
-
Guo, S.1
Lin, C.M.2
Xu, Z.3
Miao, L.4
Wang, Y.5
Huang, L.6
-
147
-
-
84878114531
-
Stromal cells in tumor microenvironment and breast cancer
-
Mao Y, Keller ET, Garfield DH, Shen K, Wang J (2013) Stromal cells in tumor microenvironment and breast cancer. Cancer metastasis rev 32(1-2):303-315. doi:10.1007/ s10555-012-9415-3
-
(2013)
Cancer metastasis rev
, vol.32
, Issue.1-2
, pp. 303-315
-
-
Mao, Y.1
Keller, E.T.2
Garfield, D.H.3
Shen, K.4
Wang, J.5
-
148
-
-
38849141696
-
Cancer-associated stromal fibroblasts promote pancreatic tumor progression
-
Hwang RF, Moore T, Arumugam T, Ramachandran V, Amos KD, Rivera A, Ji B, Evans DB, Logsdon CD (2008) Cancer-associated stromal fibroblasts promote pancreatic tumor progression. Cancer Res 68(3):918-926. doi:10.1158/0008-5472.CAN-07-5714
-
(2008)
Cancer Res
, vol.68
, Issue.3
, pp. 918-926
-
-
Hwang, R.F.1
Moore, T.2
Arumugam, T.3
Ramachandran, V.4
Amos, K.D.5
Rivera, A.6
Ji, B.7
Evans, D.B.8
Logsdon, C.D.9
-
149
-
-
84856934228
-
Rationale behind targeting fibroblast activation protein-expressing carcinoma-associated fibroblasts as a novel chemotherapeutic strategy
-
Brennen WN, Isaacs JT, Denmeade SR (2012) Rationale behind targeting fibroblast activation protein-expressing carcinoma-associated fibroblasts as a novel chemotherapeutic strategy. Mol Cancer Ther 11(2):257-266. doi:10.1158/1535-7163.MCT-11-0340
-
(2012)
Mol Cancer Ther
, vol.11
, Issue.2
, pp. 257-266
-
-
Brennen, W.N.1
Isaacs, J.T.2
Denmeade, S.R.3
-
150
-
-
84899457547
-
Nanoparticle-delivered transforming growth factor-beta siRNA enhances vaccination against advanced melanoma by modifying tumor microenvironment
-
Xu Z, Wang Y, Zhang L, Huang L (2014) Nanoparticle-delivered transforming growth factor-beta siRNA enhances vaccination against advanced melanoma by modifying tumor microenvironment. ACS Nano 8(4):3636-3645. doi:10.1021/nn500216y
-
(2014)
ACS Nano
, vol.8
, Issue.4
, pp. 3636-3645
-
-
Xu, Z.1
Wang, Y.2
Zhang, L.3
Huang, L.4
-
151
-
-
84902482580
-
Pancreatic cancer stroma: Friend or foe?
-
Gore J, Korc M (2014) Pancreatic cancer stroma: friend or foe? Cancer Cell 25(6):711-712. doi:10.1016/j.ccr.2014.05.026
-
(2014)
Cancer Cell
, vol.25
, Issue.6
, pp. 711-712
-
-
Gore, J.1
Korc, M.2
-
152
-
-
84902435628
-
Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma
-
Rhim AD, Oberstein PE, Thomas DH, Mirek ET, Palermo CF, Sastra SA, Dekleva EN, Saunders T, Becerra CP, Tattersall IW, Westphalen CB, Kitajewski J, Fernandez-Barrena MG, Fernandez-Zapico ME, Iacobuzio-Donahue C, Olive KP, Stanger BZ (2014) Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma. Cancer Cell 25(6):735-747. doi:10.1016/j.ccr.2014.04.021
-
(2014)
Cancer Cell
, vol.25
, Issue.6
, pp. 735-747
-
-
Rhim, A.D.1
Oberstein, P.E.2
Thomas, D.H.3
Mirek, E.T.4
Palermo, C.F.5
Sastra, S.A.6
Dekleva, E.N.7
Saunders, T.8
Becerra, C.P.9
Tattersall, I.W.10
Westphalen, C.B.11
Kitajewski, J.12
Fernandez-Barrena, M.G.13
Fernandez-Zapico, M.E.14
Iacobuzio-Donahue, C.15
Olive, K.P.16
Stanger, B.Z.17
-
153
-
-
0035834121
-
Senescent fibroblasts promote epithelial cell growth and tumorigenesis: A link between cancer and aging
-
Krtolica A, Parrinello S, Lockett S, Desprez PY, Campisi J (2001) Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging. Proc Natl Acad Sci USA 98(21):12072-12077. doi:10.1073/pnas.211053698
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, Issue.21
, pp. 12072-12077
-
-
Krtolica, A.1
Parrinello, S.2
Lockett, S.3
Desprez, P.Y.4
Campisi, J.5
-
154
-
-
84904330291
-
Engineered nanomedicine for myeloma and bone microenvironment targeting
-
Swami A, Reagan MR, Basto P, Mishima Y, Kamaly N, Glavey S, Zhang S, Moschetta M, Seevaratnam D, Zhang Y, Liu J, Memarzadeh M, Wu J, Manier S, Shi J, Bertrand N, Lu ZN, Nagano K, Baron R, Sacco A, Roccaro AM, Farokhzad OC, Ghobrial IM (2014) Engineered nanomedicine for myeloma and bone microenvironment targeting. Proc Natl Acad Sci USA 111(28):10287-10292. doi:10.1073/pnas.1401337111
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, Issue.28
, pp. 10287-10292
-
-
Swami, A.1
Reagan, M.R.2
Basto, P.3
Mishima, Y.4
Kamaly, N.5
Glavey, S.6
Zhang, S.7
Moschetta, M.8
Seevaratnam, D.9
Zhang, Y.10
Liu, J.11
Memarzadeh, M.12
Wu, J.13
Manier, S.14
Shi, J.15
Bertrand, N.16
Lu, Z.N.17
Nagano, K.18
Baron, R.19
Sacco, A.20
Roccaro, A.M.21
Farokhzad, O.C.22
Ghobrial, I.M.23
more..
-
155
-
-
84862007577
-
Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET
-
Peinado H, Aleckovic M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, Hergueta- Redondo M, Williams C, Garcia-Santos G, Ghajar C, Nitadori-Hoshino A, Hoffman C, Badal K, Garcia BA, Callahan MK, Yuan J, Martins VR, Skog J, Kaplan RN, Brady MS, Wolchok JD, Chapman PB, Kang Y, Bromberg J, Lyden D (2012) Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Nat Med 18 (6):883-891. doi:10.1038/nm.2753
-
(2012)
Nat Med
, vol.18
, Issue.6
, pp. 883-891
-
-
Peinado, H.1
Aleckovic, M.2
Lavotshkin, S.3
Matei, I.4
Costa-Silva, B.5
Moreno-Bueno, G.6
Hergueta- Redondo, M.7
Williams, C.8
Garcia-Santos, G.9
Ghajar, C.10
Nitadori-Hoshino, A.11
Hoffman, C.12
Badal, K.13
Garcia, B.A.14
Callahan, M.K.15
Yuan, J.16
Martins, V.R.17
Skog, J.18
Kaplan, R.N.19
Brady, M.S.20
Wolchok, J.D.21
Chapman, P.B.22
Kang, Y.23
Bromberg, J.24
Lyden, D.25
more..
|