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Volumn 18, Issue 2, 2015, Pages 128-135

Trade-Offs in the Effects of the Apolipoprotein E Polymorphism on Risks of Diseases of the Heart, Cancer, and Neurodegenerative Disorders: Insights on Mechanisms from the Long Life Family Study

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E; APOLIPOPROTEIN E4;

EID: 84928490466     PISSN: 15491684     EISSN: 15578577     Source Type: Journal    
DOI: 10.1089/rej.2014.1616     Document Type: Article
Times cited : (14)

References (53)
  • 2
    • 35948967250 scopus 로고    scopus 로고
    • Pursuing the longevity dividend: Scientific goals for an aging world
    • Olshansky SJ, Perry D, Miller RA, Butler RN. Pursuing the longevity dividend: Scientific goals for an aging world. Ann NY Acad Sci 2007;1114:11-13.
    • (2007) Ann NY Acad Sci , vol.1114 , pp. 11-13
    • Olshansky, S.J.1    Perry, D.2    Miller, R.A.3    Butler, R.N.4
  • 3
    • 84855925920 scopus 로고    scopus 로고
    • Rare and common variants: Twenty arguments
    • Gibson G. Rare and common variants: Twenty arguments. Nat Rev Genet 2011;13:135-145.
    • (2011) Nat Rev Genet , vol.13 , pp. 135-145
    • Gibson, G.1
  • 5
    • 34547617380 scopus 로고    scopus 로고
    • Genetic determinants of human health span and life span: Progress and new opportunities
    • Martin GM, Bergman A, Barzilai N. Genetic determinants of human health span and life span: Progress and new opportunities. PLoS Genet 2007;3:e125.
    • (2007) PLoS Genet , vol.3 , pp. e125
    • Martin, G.M.1    Bergman, A.2    Barzilai, N.3
  • 8
    • 30844471395 scopus 로고    scopus 로고
    • Diabetes mellitus in the elderly: Insulin resistance and/or impaired insulin secretion?
    • Scheen AJ. Diabetes mellitus in the elderly: Insulin resistance and/or impaired insulin secretion? Diabetes Metab 2005;31(Spec No 2):5S27-25S34.
    • (2005) Diabetes Metab , vol.31 , pp. 5S27-25S34
    • Scheen, A.J.1
  • 9
    • 33845960789 scopus 로고    scopus 로고
    • Insights on aging and exceptional longevity from longitudinal data: Novel findings from the Framingham Heart Study
    • Yashin AI, Akushevich IV, Arbeev KG, Akushevich L, Ukraintseva SV, Kulminski A. Insights on aging and exceptional longevity from longitudinal data: Novel findings from the Framingham Heart Study. Age 2006;28:363-374.
    • (2006) Age , vol.28 , pp. 363-374
    • Yashin, A.I.1    Akushevich, I.V.2    Arbeev, K.G.3    Akushevich, L.4    Ukraintseva, S.V.5    Kulminski, A.6
  • 11
    • 84857064295 scopus 로고    scopus 로고
    • Age patterns of incidence of geriatric disease in the U.S. elderly population: Medicare-based analysis
    • Akushevich I, Kravchenko J, Ukraintseva S, Arbeev K, Yashin AI. Age patterns of incidence of geriatric disease in the U.S. elderly population: Medicare-based analysis. J Am Geriatr Soc 2012;60:323-327.
    • (2012) J Am Geriatr Soc , vol.60 , pp. 323-327
    • Akushevich, I.1    Kravchenko, J.2    Ukraintseva, S.3    Arbeev, K.4    Yashin, A.I.5
  • 12
    • 0030713963 scopus 로고    scopus 로고
    • Genetics of aging
    • Finch CE, Tanzi RE. Genetics of aging. Science 1997;278:407-411.
    • (1997) Science , vol.278 , pp. 407-411
    • Finch, C.E.1    Tanzi, R.E.2
  • 13
    • 0036814370 scopus 로고    scopus 로고
    • Biological aging research today: Potential, peeves, and problems
    • Jazwinski SM. Biological aging research today: Potential, peeves, and problems. Exp Gerontol 2002;37:1141-1146.
    • (2002) Exp Gerontol , vol.37 , pp. 1141-1146
    • Jazwinski, S.M.1
  • 16
    • 62549085618 scopus 로고    scopus 로고
    • Human genetic variation and its contribution to complex traits
    • Frazer KA, Murray SS, Schork NJ, Topol EJ. Human genetic variation and its contribution to complex traits. Nat Rev Genet 2009;10:241-251.
    • (2009) Nat Rev Genet , vol.10 , pp. 241-251
    • Frazer, K.A.1    Murray, S.S.2    Schork, N.J.3    Topol, E.J.4
  • 20
    • 77957745948 scopus 로고    scopus 로고
    • The origins and evolution of genetic disease risk in modern humans
    • Crespi BJ. The origins and evolution of genetic disease risk in modern humans. Ann NY Acad Sci 2010;1206:80-109.
    • (2010) Ann NY Acad Sci , vol.1206 , pp. 80-109
    • Crespi, B.J.1
  • 22
    • 0035194748 scopus 로고    scopus 로고
    • Expression of inducible Hsp70 enhances the proliferation of MCF-7 breast cancer cells and protects against the cytotoxic effects of hyperthermia
    • Barnes JA, Dix DJ, Collins BW, Luft C, Allen JW. Expression of inducible Hsp70 enhances the proliferation of MCF-7 breast cancer cells and protects against the cytotoxic effects of hyperthermia. Cell Stress Chaperones 2001;6:316-325.
    • (2001) Cell Stress Chaperones , vol.6 , pp. 316-325
    • Barnes, J.A.1    Dix, D.J.2    Collins, B.W.3    Luft, C.4    Allen, J.W.5
  • 23
    • 0000055057 scopus 로고
    • Pleiotropy, natural-selection, and the evolution of senescence
    • Williams GC. Pleiotropy, natural-selection, and the evolution of senescence. Evolution 1957;11:398-411.
    • (1957) Evolution , vol.11 , pp. 398-411
    • Williams, G.C.1
  • 24
    • 34249729839 scopus 로고    scopus 로고
    • Modalities of gene action predicted by the classical evolutionary biological theory of aging
    • Martin GM. Modalities of gene action predicted by the classical evolutionary biological theory of aging. Ann NY Acad Sci 2007;1100:14-20.
    • (2007) Ann NY Acad Sci , vol.1100 , pp. 14-20
    • Martin, G.M.1
  • 25
    • 0042697664 scopus 로고    scopus 로고
    • Antagonistic pleiotropy, mortality source interactions, and the evolutionary theory of senescence
    • Williams PD, Day T. Antagonistic pleiotropy, mortality source interactions, and the evolutionary theory of senescence. Evolution 2003;57:1478-1488.
    • (2003) Evolution , vol.57 , pp. 1478-1488
    • Williams, P.D.1    Day, T.2
  • 26
    • 77953082631 scopus 로고    scopus 로고
    • Beta2-adrenergic receptor gene polymorphisms as systemic determinants of healthy aging in an evolutionary context
    • Kulminski AM, Culminskaya I, Ukraintseva SV, Arbeev KG, Land KC, Yashin AI. Beta2-adrenergic receptor gene polymorphisms as systemic determinants of healthy aging in an evolutionary context. Mech Ageing Dev 2010;131:338-345.
    • (2010) Mech Ageing Dev , vol.131 , pp. 338-345
    • Kulminski, A.M.1    Culminskaya, I.2    Ukraintseva, S.V.3    Arbeev, K.G.4    Land, K.C.5    Yashin, A.I.6
  • 27
    • 77954838941 scopus 로고    scopus 로고
    • Xmrks the spot: Life history tradeoffs, sexual selection and the evolutionary ecology of oncogenesis
    • Summers K, Crespi BJ. Xmrks the spot: Life history tradeoffs, sexual selection and the evolutionary ecology of oncogenesis. Mol Ecol 2010;19:3022-3024.
    • (2010) Mol Ecol , vol.19 , pp. 3022-3024
    • Summers, K.1    Crespi, B.J.2
  • 29
    • 0010007277 scopus 로고
    • Antagonistic pleiotropy - An interspecific Drosophila comparison
    • Schnebel EM, Grossfield J. Antagonistic pleiotropy - an interspecific Drosophila comparison. Evolution 1988;42:306-311.
    • (1988) Evolution , vol.42 , pp. 306-311
    • Schnebel, E.M.1    Grossfield, J.2
  • 33
    • 34548442083 scopus 로고    scopus 로고
    • Buffering mechanisms in aging: A systems approach toward uncovering the genetic component of aging
    • Bergman A, Atzmon G, Ye K, MacCarthy T, Barzilai N. Buffering mechanisms in aging: A systems approach toward uncovering the genetic component of aging. PLoS Comput Biol 2007;3:e170.
    • (2007) PLoS Comput Biol , vol.3 , pp. e170
    • Bergman, A.1    Atzmon, G.2    Ye, K.3    MacCarthy, T.4    Barzilai, N.5
  • 34
    • 84874234377 scopus 로고    scopus 로고
    • Trade-off in the effect of the APOE gene on the ages at onset of cardiocascular disease and cancer across ages, gender, and human generations
    • Kulminski AM, Culminskaya I, Arbeev KG, Ukraintseva SV, Arbeeva L, Yashin AI. Trade-off in the effect of the APOE gene on the ages at onset of cardiocascular disease and cancer across ages, gender, and human generations. Rejuvenation Res 2013;16:28-34.
    • (2013) Rejuvenation Res , vol.16 , pp. 28-34
    • Kulminski, A.M.1    Culminskaya, I.2    Arbeev, K.G.3    Ukraintseva, S.V.4    Arbeeva, L.5    Yashin, A.I.6
  • 35
    • 0030863012 scopus 로고    scopus 로고
    • Evidence that the apolipoprotein E-genotype effects on lipid levels can change with age in males: A longitudinal analysis
    • Jarvik GP, Goode EL, Austin MA, Auwerx J, Deeb S, Schellenberg GD, Reed T. Evidence that the apolipoprotein E-genotype effects on lipid levels can change with age in males: A longitudinal analysis. Am J Hum Genet 1997;61:171-181.
    • (1997) Am J Hum Genet , vol.61 , pp. 171-181
    • Jarvik, G.P.1    Goode, E.L.2    Austin, M.A.3    Auwerx, J.4    Deeb, S.5    Schellenberg, G.D.6    Reed, T.7
  • 38
    • 33751395235 scopus 로고    scopus 로고
    • The Danish Civil Registration System. A cohort of eight million persons
    • Pedersen CB, Gotzsche H, Moller JO, Mortensen PB. The Danish Civil Registration System. A cohort of eight million persons. Dan Med Bull 2006;53:441-449.
    • (2006) Dan Med Bull , vol.53 , pp. 441-449
    • Pedersen, C.B.1    Gotzsche, H.2    Moller, J.O.3    Mortensen, P.B.4
  • 41
    • 84882355149 scopus 로고    scopus 로고
    • Unraveling genetic origin of aging-related traits: Evolving concepts
    • Kulminski AM. Unraveling genetic origin of aging-related traits: Evolving concepts. Rejuvenation Res 2013;16:304-312.
    • (2013) Rejuvenation Res , vol.16 , pp. 304-312
    • Kulminski, A.M.1
  • 42
    • 84907958813 scopus 로고    scopus 로고
    • Aging and cardiovascular diseases: The role of gene-diet interactions
    • Corella D, Ordovas JM. Aging and cardiovascular diseases: The role of gene-diet interactions. Ageing Res Rev 2014;18C:53-73.
    • (2014) Ageing Res Rev , vol.18 C , pp. 53-73
    • Corella, D.1    Ordovas, J.M.2
  • 44
    • 3142706539 scopus 로고    scopus 로고
    • Meta-analysis: Apolipoprotein E genotypes and risk for coronary heart disease
    • Song Y, Stampfer MJ, Liu S. Meta-analysis: apolipoprotein E genotypes and risk for coronary heart disease. Ann Intern Med 2004;141:137-147.
    • (2004) Ann Intern Med , vol.141 , pp. 137-147
    • Song, Y.1    Stampfer, M.J.2    Liu, S.3
  • 46
    • 84875477674 scopus 로고    scopus 로고
    • Inverse cancer comorbidity: A serendipitous opportunity to gain insight into CNS disorders
    • Tabares-Seisdedos R, Rubenstein JL. Inverse cancer comorbidity: A serendipitous opportunity to gain insight into CNS disorders. Nat Rev Neurosci 2013;14:293-304.
    • (2013) Nat Rev Neurosci , vol.14 , pp. 293-304
    • Tabares-Seisdedos, R.1    Rubenstein, J.L.2
  • 47
    • 84864945361 scopus 로고    scopus 로고
    • Polygenic effects of common single-nucleotide polymorphisms on life span: When association meets causality
    • Yashin AI, Wu D, Arbeev KG, Ukraintseva SV. Polygenic effects of common single-nucleotide polymorphisms on life span: When association meets causality. Rejuvenation Res 2012;15:381-394.
    • (2012) Rejuvenation Res , vol.15 , pp. 381-394
    • Yashin, A.I.1    Wu, D.2    Arbeev, K.G.3    Ukraintseva, S.V.4
  • 48
    • 79953733858 scopus 로고    scopus 로고
    • The effect of next-generation sequencing technology on complex trait research
    • Day-Williams AG, Zeggini E. The effect of next-generation sequencing technology on complex trait research. Eur J Clin Invest 2011;41:561-567.
    • (2011) Eur J Clin Invest , vol.41 , pp. 561-567
    • Day-Williams, A.G.1    Zeggini, E.2
  • 49
    • 77951702343 scopus 로고    scopus 로고
    • Genetic heterogeneity in human disease
    • McClellan J, King MC. Genetic heterogeneity in human disease. Cell 2010;141:210-217.
    • (2010) Cell , vol.141 , pp. 210-217
    • McClellan, J.1    King, M.C.2
  • 50
    • 4143134235 scopus 로고    scopus 로고
    • The future of association studies: Gene-based analysis and replication
    • Neale BM, Sham PC. The future of association studies: Gene-based analysis and replication. Am J Hum Genet 2004;75:353-362.
    • (2004) Am J Hum Genet , vol.75 , pp. 353-362
    • Neale, B.M.1    Sham, P.C.2
  • 52
    • 33646863656 scopus 로고    scopus 로고
    • The quest for genetic determinants of human longevity: Challenges and insights
    • Christensen K, Johnson TE, Vaupel JW. The quest for genetic determinants of human longevity: Challenges and insights. Nat Rev Genet 2006;7:436-448.
    • (2006) Nat Rev Genet , vol.7 , pp. 436-448
    • Christensen, K.1    Johnson, T.E.2    Vaupel, J.W.3


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