"Predicting" parental longevity from offspring endophenotypes: Data from the Long Life Family Study (LLFS)

Mechanisms of Ageing and Development

Volumn 131, Issue 3, 2010, Pages 215-222

  Yashin, Anatoli I ^a   Arbeev, Konstantin G ^a   Kulminski, Alexander ^a   Borecki, Ingrid ^b   Christensen, Kaare ^c   Barmada, Michael ^d   Hadley, Evan ^e   Rossi, Winifred ^e   Lee, Joseph H ^f   Cheng, Rong ^f   Elo, Irma T ^g  

^a DUKE UNIVERSITY   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^d UNIVERSITY OF PITTSBURGH   (United States)

^e NATIONAL INSTITUTE ON AGING   (United States)

^f Mailman School of Public Health ^*  (United States)

^g UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Determinants of life span; Genetics of human longevity; Incomplete data; Longevity in families; Probands

Indexed keywords

AGED; ARTICLE; BRAIN FUNCTION; COGNITION; CONTROLLED STUDY; FAMILY STUDY; FEMALE; HEALTH STATUS; HERITABILITY; HUMAN; INHERITANCE; LIFESPAN; LONGEVITY; MALE; PARENT; PHENOTYPE; PREDICTION; PRIORITY JOURNAL; PROGENY; SURVIVAL TIME; WELLBEING;

FAMILY; FAMILY RELATIONS; HEALTH SERVICES; HUMANS; LONGEVITY; MALE; PARENTS; RESEARCH; SURVIVAL;

EID: 77950051577     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mad.2010.02.001     Document Type: Article

References (48)

1. Abbott M.H., Murphy E.A., Bolling D.R., Abbey H. The familial component in longevity. A study of offspring of nonagenarians. II. Preliminary analysis of the completed study. Johns Hopkins Med. J. 1974, 134(1):1-16.
2. Allison D.B., Fontaine K.R., Manson J.E., Stevens J., VanItallie T.B. Annual deaths attributable to obesity in the United States. JAMA 1999, 282(16):1530-1538.
3. Atzmon G., Rincon M., Schechter C.B., Shuldiner A.R., Lipton R.B., Bergman A., Barzilai N. Lipoprotein genotype and conserved pathway for exceptional longevity in humans. PLoS Biol. 2006, 4(4):e113.
4. Aviv A. Hypothesis: pulse pressure and human longevity. Hypertension 2001, 37(4):1060-1066.
5. Baldassarre D., Amato M., Veglia F., Pustina L., Castelnuovo S., Sanvito S., Gerosa L., Sirtori C.R., Tremoli E. Correlation of parents' longevity with carotid intima-media thickness in patients attending a Lipid Clinic. Atherosclerosis 2005, 179(1):111-117.
6. Barzilai N., Shuldiner A.R. Searching for human longevity genes: the future history of gerontology in the post-genomic era. J. Gerontol. A: Biol. Sci. Med. Sci. 2001, 56(2):M83-87.
7. Bocquet-Appel J.P., Jakobi L. Familial transmission of longevity. Ann. Hum. Biol. 1990, 17(2):81-95.
8. Boutitie F., Gueyffier F., Pocock S., Fagard R., Boissel J.P. J-shaped relationship between blood pressure and mortality in hypertensive patients: new insights from a meta-analysis of individual-patient data. Ann. Intern. Med. 2002, 136(6):438-448.
9. Brand F.N., Kiely D.K., Kannel W.B., Myers R.H. Family patterns of coronary heart disease mortality: the Framingham Longevity Study. J. Clin. Epidemiol. 1992, 45(2):169-174.
10. Clarkwest A. Neo-materialist theory and the temporal relationship between income inequality and longevity change. Soc. Sci. Med. 2008, 66(9):1871-1881.
11. Cournil A., Kirkwood T.B. If you would live long, choose your parents well. Trends Genet. 2001, 17(5):233-235.
12. Cournil A., Legay J.M., Schachter F. Evidence of sex-linked effects on the inheritance of human longevity: a population-based study in the Valserine valley (French Jura), 18-20th centuries. Proc. Biol. Sci. 2000, 267(1447):1021-1025.
13. Crawford M.H., Rogers L. Population genetic models in the study of aging and longevity in a Mennonite community. Soc. Sci. Med. 1982, 16(2):149-153.
14. de Groot V., Beckerman H., Lankhorst G.J., Bouter L.M. How to measure comorbidity: a critical review of available methods. J. Clin. Epidemiol. 2003, 56(3):221-229.
15. Franceschi C., Bezrukov V., Blanche H., Bolund L., Christensen K., de Benedictis G., Deiana L., Gonos E., Hervonen A., Yang H., Jeune B., Kirkwood T.B., Kristensen P., Leon A., Pelicci P.G., Peltonen L., Poulain M., Rea I.M., Remacle J., Robine J.M., Schreiber S., Sikora E., Slagboom P.E., Spazzafumo L., Stazi M.A., Toussaint O., Vaupel J.W. Genetics of healthy aging in Europe: the EU-integrated project GEHA (GEnetics of Healthy Aging). Ann. NY Acad. Sci. 2007, 1100:21-45.
16. Fried L.P., Tangen C.M., Walston J., Newman A.B., Hirsch C., Gottdiener J., Seeman T., Tracy R., Kop W.J., Burke G., McBurnie M.A. Frailty in older adults: evidence for a phenotype. J. Gerontol. A: Biol. Sci. Med. Sci. 2001, 56(3):M146-156.
17. Fried L.P., Xue Q.L., Cappola A.R., Ferrucci L., Chaves P., Varadhan R., Guralnik J.M., Leng S.X., Semba R.D., Walston J.D., Blaum C.S., Bandeen-Roche K. Nonlinear multisystem physiological dysregulation associated with frailty in older women: implications for etiology and treatment. J. Gerontol. A: Biol. Sci. Med. Sci. 2009, 64(10):1049-1057.
18. Golubovsky M.D., Weisman N.Y., Arbeev K.G., Ukraintseva S.V., Yashin A.I. Decrease in the lgl tumor suppressor dose in Drosophila increases survival and longevity in stress conditions. Exp. Gerontol. 2006, 41(9):819-827.
19. Kemkes-Grottenthaler A. Parental effects on offspring longevity-evidence from 17th to 19th century reproductive histories. Ann. Hum. Biol. 2004, 31(2):139-158.
20. Kim S., Symons M., Popkin B.M. Contrasting socioeconomic profiles related to healthier lifestyles in China and the United States. Am. J. Epidemiol. 2004, 159(2):184-191.
21. Kokaze A., Ishikawa M., Matsunaga N., Yoshida M., Satoh M., Teruya K., Honmyo R., Shirasawa T., Hoshino H., Takashima Y. Longevity-associated mitochondrial DNA 5178 C/A polymorphism and its interaction with cigarette consumption are associated with pulmonary function in middle-aged Japanese men. J. Hum. Genet. 2007, 52(8):680-685.
22. Korpelainen H. Genetic maternal effects on human life span through the inheritance of mitochondrial DNA. Hum. Hered. 1999, 49(4):183-185.
23. Korpelainen H. Variation in the heritability and evolvability of human lifespan. Naturwissenschaften 2000, 87(12):566-568.
24. Kulminski A.M., Arbeev K.G., Culminskaya I.V., Ukraintseva S.V., Christensen K., Yashin A.I. Health-related phenotypes and longevity in Danish twins. J. Gerontol. A: Biol. Sci. Med. Sci. 2009, 64(1):1-8.
25. Kulminski A.M., Arbeev K.G., Kulminskaya I.V., Ukraintseva S.V., Land K., Akushevich I., Yashin A.I. Body mass index and nine-year mortality in disabled and nondisabled older U.S. Individuals. J. Am. Geriatr. Soc. 2008, 56(1):105-110.
26. Kulminski A.M., Ukraintseva S.V., Kulminskaya I.V., Arbeev K.G., Land K., Yashin A.I. Cumulative deficits better characterize susceptibility to death in elderly people than phenotypic frailty: lessons from the Cardiovascular Health Study. J. Am. Geriatr. Soc. 2008, 56(5):898-903.
27. Lande R., Kirkpatrick M. Selection response in traits with maternal inheritance. Genet. Res. 1990, 55(3):189-197.
28. Landgren O., Bjorkholm M., Granath F., Ekbom A. Familial longevity: the older you are, the older your father may have been. J. Am. Geriatr. Soc. 2005, 53(2):357-358.
29. Lee E., Wei L., Amato D. Cox-Type Regression Analysis for Large Numbers of Small Groups of Correlated Failure Time Observations 1992, Kluwer Academic Publishers, Netherlands.
30. Levitan E.B., Song Y.Q., Ford E.S., Liu S.M. Is nondiabetic hyperglycemia a risk factor for cardiovascular disease? A meta-analysis of prospective studies. Arch. Intern. Med. 2004, 164(19):2147-2155.
31. Lynch J.W., Smith G.D., Kaplan G.A., House J.S. Income inequality and mortality: importance to health of individual income, psychosocial environment, or material conditions. BMJ 2000, 320(7243):1200-1204.
32. Martin G.M., Bergman A., Barzilai N. Genetic determinants of human health span and life span: progress and new opportunities. PLoS Genet. 2007, 3(7):e125.
33. Melzer D., Hurst A.J., Frayling T. Genetic variation and human aging: progress and prospects. J. Gerontol. A: Biol. Sci. Med. Sci. 2007, 62(3):301-307.
34. Okumiya K., Matsubayashi K., Wada T., Fujisawa M., Osaki Y., Doi Y., Yasuda N., Ozawa T. A U-shaped association between home systolic blood pressure and four-year mortality in community-dwelling older men. J. Am. Geriatr. Soc. 1999, 47(12):1415-1421.
35. Pearl R. A note on the inheritance of duration of life in man. Am. J. Hyg. 1922, 2(3):229-233.
36. Perls T., Terry D. Understanding the determinants of exceptional longevity. Ann. Intern. Med. 2003, 139(5 Pt 2):445-449.
37. Philippe P. Familial correlations of longevity: an isolate-based study. Am. J. Med. Genet. 1978, 2(2):121-129.
38. Protogerou A.D., Safar M.E., Iaria P., Safar H., Le Dudal K., Filipovsky J., Henry O., Ducimetiere P., Blacher J. Diastolic blood pressure and mortality in the elderly with cardiovascular disease. Hypertension 2007, 50(1):172-180.
39. Puts M.T., Lips P., Deeg D.J. Sex differences in the risk of frailty for mortality independent of disability and chronic diseases. J. Am. Geriatr. Soc. 2005, 53(1):40-47.
40. Reed T., Carmelli D., Robinson T.S., Rinehart S.A., Williams C.J. More favorable midlife cardiovascular risk factor levels in male twins and mortality after 25 years of follow-up is related to longevity of their parents. J. Gerontol. A: Biol. Sci. Med. Sci. 2003, 58(4):367-371.
41. Rockwood K., Mitnitski A. Frailty in relation to the accumulation of deficits. J. Gerontol. A: Biol. Sci. Med. Sci. 2007, 62(7):722-727.
42. Rockwood K., Mitnitski A., Song X., Steen B., Skoog I. Long-term risks of death and institutionalization of elderly people in relation to deficit accumulation at age 70. J. Am. Geriatr. Soc. 2006, 54(6):975-979.
43. Sebastiani P., Hadley E.C., Province M., Christensen K., Rossi W., Perls T.T., Ash A.S. A Family Longevity Selection Score: ranking sibships by their longevity, size, and availability for study. Am. J. Epidemiol. 2009, 170(12):1555-1562.
44. Seeman T.E., McEwen B.S., Rowe J.W., Singer B.H. Allostatic load as a marker of cumulative biological risk: MacArthur studies of successful aging. Proc. Natl. Acad. Sci. U.S.A. 2001, 98(8):4770-4775.
45. Yashin A.I., Akushevich I.V., Arbeev K.G., Akushevich L., Ukraintseva S.V., Kulminski A. Insights on aging and exceptional longevity from longitudinal data: novel findings from the Framingham Heart Study. Age 2006, 28(4):363-374.
46. Yashin, A.I., Arbeev, K.G., Akushevich, I., Ukraintseva, S.V., Kulminski, A., Arbeeva, L.S., Culminskaya, I., in press. Exceptional survivors have lower age trajectories of blood glucose: lessons from longitudinal data. Biogerontology, doi:10.1007/s10522-009-9243-1.
47. Yashin A.I., Ukraintseva S.V., Arbeev K.G., Akushevich I., Arbeeva L.S., Kulminski A.M. Maintaining physiological state for exceptional survival: what is the normal level of blood glucose and does it change with age?. Mech. Ageing Dev. 2009, 130(9):611-618.
48. Yu D., Gu D., Yi Z. Familial transmission of human longevity among the oldest-old in China. Presented at the 2006 Annual Meeting of the Population Association of America 2006, 16. (Unpublished).