The ethanol extract of Osmanthus fragrans attenuates Porphyromonas gingivalis lipopolysaccharide-stimulated inflammatory effect through the nuclear factor erythroid 2-related factor-mediated antioxidant signalling pathway

Archives of Oral Biology

Volumn 60, Issue 7, 2015, Pages 1030-1038

  Bin, Huang ^a,b   Huangqin, Chen ^b   Longquan, Shao ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b HUBEI UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Inflammation; Lipopolysaccharide; Nuclear factor erythroid 2 related factor; Osmanthus fragrans; Porphyromonas gingivalis

Indexed keywords

OSMANTHUS FRAGRANS; PORPHYROMONAS GINGIVALIS;

COLLAGENASE; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MALONALDEHYDE; NFE2L2 PROTEIN, HUMAN; NITRIC OXIDE; PLANT EXTRACT; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2;

ADOLESCENT; ADULT; CHEMISTRY; DRUG EFFECTS; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYMOLOGY; HUMAN; METABOLISM; OLEACEAE; OXIDATIVE STRESS; PORPHYROMONAS GINGIVALIS; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ADOLESCENT; ADULT; BLOTTING, WESTERN; COLLAGENASES; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; INTERLEUKIN-6; INTERLEUKIN-8; LIPOPOLYSACCHARIDES; MALONDIALDEHYDE; NF-E2-RELATED FACTOR 2; NITRIC OXIDE; OLEACEAE; OXIDATIVE STRESS; PLANT EXTRACTS; PORPHYROMONAS GINGIVALIS; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE;

EID: 84928485623     PISSN: 00039969     EISSN: 18791506     Source Type: Journal    
DOI: 10.1016/j.archoralbio.2015.02.026     Document Type: Article

References (41)

1. Q.T. Wang, Z.F. Wu, Y.F. Wu, R. Shu, Y.P. Pan, and J.L. Xia Epidemiology and preventive direction of periodontology in China J Clin Periodontol 34 2007 946 951
2. R.C. Oliver, L.J. Brown, and H. Loë Periodontial disease in the United States population J Periodontol 69 1998 269 278
3. J. Slots, and M. Ting Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in human periodontal disease: occurrence and treatment Periodontology 2000 20 1999 82 121
4. H. Kato, Y. Taguchi, K. Tominaga, M. Umeda, and A. Tanaka Porphyromonas gingivalis LPS inhibits osteoblastic differentiation and promotes pro-inflammatory cytokine production in human periodontal ligament stem cells Arch Oral Biol 59 2014 167 175
5. S.P. Nair, S. Meghji, M. Wilson, K. Reddi, P. White, and B. Henderson Bacterially induced bone destruction: mechanisms and misconceptions Infect Immun 64 1996 2371 2380
6. C. Aznar, C. Fitting, and J.M. Cavaillon Lipopolysaccharide-induced production of cytokines by bone marrow-derived macrophages: dissociation between intracellular interleukin 1 production and interleukin 1 release Cytokine 2 1990 259 265
7. B.F. Boyce, T.B. Aufdemorte, I.R. Garrett, A.J. Yates, and G.R. Mundy Effects of interleukin-1 on bone turnover in normal mice Endocrinology 125 1989 1142 1150
8. M. Gowen, D.D. Wood, E.J. Ihrie, M.K. McGuire, and R.G. Russell An interleukin 1 like factor stimulates bone resorption in vitro Nature 306 1983 378 380
9. S.S. Socransky, and A.D. Haffajee Microbial mechanisms in the pathogenesis of destructive periodontal diseases: a critical assessment J Periodontal Res 26 1991 195 212
10. A. Scalbert, I.T. Johnson, and M. Saltmarsh Polyphenols: antioxidants and beyond Am J Clin Nutr 81 2005 215 217
11. E.I.H. Gharras Polyphenols: food sources, properties and applications - a review Int J Food Sci Technol 44 2009 2512 2518
12. J.M. Landete Updated knowledge about polyphenols: functions, bioavailability, metabolism, and health Crit Rev Food Sci Nutr 52 2012 936 948
13. C. Manach, A. Scalbert, C. Morand, C. Rémésy, and L. Jiménez Polyphenols: food sources and bioavailability Am J Clin Nutr 79 2004 727 747
14. E.J. Middleton, C. Kandaswami, and T.C. Theoharides The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease and cancer Pharmacol Rev 52 2000 673 751
15. T.C. Theoharides, M. Alexandrakis, D. Kempuraj, and M. Lytinas Anti-inflammatory actions of flavonoids and structural requirements for new design Int J Immunopathol Pharmacol 14 2001 119 127
16. D. Kempuraj, B. Madhappan, S. Christodoulou, W. Boucher, J. Cao, and N. Papadopoulou Flavonols inhibit proinflammatory mediator release, intracellular calcium ion levels and protein kinase C theta phosphorylation in human mast cells Br J Pharmacol 145 2005 934 944
17. C.Y. Hung, F.L. Huang, L.S. Shi, S.M. Ka, J.Y. Wang, and Y.C. Tsai The ethanol extract of Osmanthus fragrans flowers reduces oxidative stress and allergic airway inflammation in an animal model Evid Based Complement Altern Med 2013 2013 304290
18. C.Y. Hung, Y.C. Tsai, and K.Y. Li Phenolic antioxidants isolated from the flowers of Osmanthus fragrans Molecules 17 2012 10724 10737
19. H. Wang, D. Gan, X. Zhang, and Y. Pan Antioxidant capacity of the extracts from pulp of Osmanthus fragrans and its components LWT-Food Sci Technol 43 2009 319 325
20. D.G. Lee, S.M. Lee, M.H. Bang, H.J. Park, T.H. Lee, and Y.H. Kim Lignans from the flowers of Osmanthus fragrans var. aurantiacus and their inhibition effect on NO production Arch Pharm Res 34 2011 2029 2035
21. H.H. Lee, C.T. Lin, and L.L. Yang Neuroprotection and free radical scavenging effects of Osmanthus fragrans J Biomed Sci 14 2007 819 827
22. L.C. Wu, L.H. Chang, S.H. Chen, N.C. Fan, and J.A. Ho Antioxidant activity and melanogenesis inhibitory effect of the acetone extract of Osmanthus fragrans: a potential natural and functional food flavor additive Food Sci Technol 42 2009 1513 1519
23. S. Huang, Y. Pan, D. Gan, X. Ouyang, S. Tang, and S.I.N. Ekunwe Antioxidant activities and UV-protective properties of melanin from the berry of Cinnamomum burmannii and Osmanthus fragrans Med Chem Res 20 2011 4754 4781
24. L. Wang, L. Yu, Y. Cui, and J. Xing Flavonoids from Osmanthus fragrans: extraction and bacteriostatic activity Nat Prod Res Dev 20 2008 717 720
25. A. Marquis, S. Genovese, F. Epifano, and D. Grenier The plant coumarins auraptene and lacinartin as potential multifunctional therapeutic agents for treating periodontal disease BMC Complement Altern Med 12 2012 80
26. J. Santos, A. Marquis, F. Epifano, S. Genovese, M. Curini, and D. Grenier Collinin reduces Porphyromonas gingivalis growth and collagenase activity and inhibits the lipopolysaccharide-induced macrophage inflammatory response and osteoclast differentiation and function J Periodontol 84 2013 704 711
27. J. Cai, W. Wang, G. Chen, Z. Zhu, and H. Zhang Study on optimum extracting conditions of flavonoids from sweet-scented osmanthus Sci Technol Cereals Oils Foods 13 2005 16 18
28. D. Grenier, and V.D. La Proteases of Porphyromonas gingivalis as important virulence factors in periodontal disease and potential targets for plant-derived compounds: a review article Curr Drug Targets 12 2011 322 331
29. C.R. Irwin, and T.T. Myrillas The role of IL-6 in the pathogenesis of periodontal disease Oral Dis 4 1998 43 47
30. M. Nokhbehsaim, J. Winter, B. Rath, A. Jager, S. Jepsen, and J. Deschner Effects of enamel matrix derivative on periodontal wound healing in an inflammatory environment in vitro J Clin Periodontol 38 2011 479 490
31. H. Okada, and S. Murakami Cytokine expression in periodontal health and disease Crit Rev Oral Biol Med 9 1998 248 266
32. A. Poorsattar Bejeh-Mir, H. Parsian, M. Akbari Khoram, N. Ghasemi, A. Bijani, and M. Khosravi-Samani Diagnostic role of salivary and GCF nitrite, nitrate and nitric oxide to distinguish healthy periodontium from gingivitis and periodontitis Int J Mol Cell Med 3 2014 138 145
33. M.F. Zhang, Y.J. Huang, H.F. Zhang, W. Tang, and J. Zhou Oxidative stress and susceptibility of periodontal disease Shanghai Kou Qiang Yi Xue 22 2013 571 576
34. E. BaltacIoʇlu, P. Yuva, G. AydIn, A. Alver, C. Kahraman, and E. Karabulut Lipid peroxidation levels and total oxidant/antioxidant status in serum and saliva from patients with chronic and aggressive periodontitis. Oxidative stress index: a new biomarker for periodontal disease? J Periodontol 85 2014 1432 1441
35. D. Del Rio, A.J. Stewart, and N. Pellegrini A review of recent studies on malondialdehyde as toxic molecule and biological marker of oxidative stress Nutr Metab Cardiovasc Dis 15 2005 316 328
36. R.J. Waddington, R. Moseley, and G. Embery Reactive oxygen species: a potential role in the pathogenesis of periodontal diseases Oral Dis 6 2000 138 151
37. H. Kanzaki, F. Shinohara, M. Kajiya, and T. Kodama The Keap1/Nrf2 protein axis plays a role in osteoclast differentiation by regulating intracellular reactive oxygen species signaling J Biol Chem 288 2013 23009 23020
38. N. Tamaki, R. Cristina Orihuela-Campos, Y. Inagaki, M. Fukui, T. Nagata, and H.O. Ito Resveratrol improves oxidative stress and prevents the progression of periodontitis via the activation of the Sirt1/AMPK and the Nrf2/antioxidant defense pathways in a rat periodontitis model Free Radic Biol Med 75 2014 222 229
39. S.Y. Park, J. Park da, Y.H. Kim, Y. Kim, Y.W. Choi, and S.J. Lee Schisandra chinensis α-iso-cubebenol induces heme oxygenase-1 expression through PI3K/Akt and Nrf2 signaling and has anti-inflammatory activity in Porphyromonas gingivalis lipopolysaccharide-stimulated macrophages Int Immunopharmacol 11 2011 1907 1915
40. J.H. Chung, Y.S. Kim, K. Noh, Y.M. Lee, S.W. Chang, and E.C. Kim Deferoxamine promotes osteoblastic differentiation in human periodontal ligament cells via the nuclear factor erythroid 2-related factor-mediated antioxidant signaling pathway J Periodontal Res 49 2014 563 573
41. G.S. Jeong, D.S. Lee, B. Li, H.J. Lee, E.C. Kim, and Y.C. Kim Effects of sappanchalcone on the cytoprotection and anti-inflammation via heme oxygenase-1 in human pulp and periodontal ligament cells Eur J Pharmacol 644 2010 230 237