The Keap1/Nrf2 protein axis plays a role in osteoclast differentiation by regulating intracellular reactive oxygen species signaling

Journal of Biological Chemistry

Volumn 288, Issue 32, 2013, Pages 23009-23020

  Kanzaki, Hiroyuki ^a   Shinohara, Fumiaki ^a,b   Kajiya, Mikihito ^c   Kodama, Tetsuya ^b  

^a TOHOKU UNIVERSITY HOSPITAL   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

^c HIROSHIMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BONE DESTRUCTION; DESTRUCTIVE DISEASE; MASTER REGULATORS; NUCLEAR FACTORS; OSTEOCLAST DIFFERENTIATION; OSTEOCLASTOGENESIS; REACTIVE OXYGEN SPECIES; THERAPEUTIC TARGETS;

CHEMICAL COMPOUNDS;

ENZYMES;

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUTAMATE CYSTEINE LIGASE; HEME OXYGENASE 1; KELCH LIKE ECH ASSOCIATED PROTEIN 1; LIPOPOLYSACCHARIDE; OSTEOCLAST DIFFERENTIATION FACTOR; PLASMID VECTOR; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BONE DESTRUCTION; CELL DIFFERENTIATION; CELL PROTECTION; CELLULAR STRESS RESPONSE; CELLULAR STRESS SIGNAL; CONTROLLED STUDY; DOWN REGULATION; ENZYME REGULATION; EXPRESSION VECTOR; GENE OVEREXPRESSION; GENE SILENCING; GENE TRANSFER; IN VITRO STUDY; IN VIVO STUDY; KEAP1 GENE; MALE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NONVIRAL GENE THERAPY; NRF2 GENE; OSTEOCLAST; OSTEOCLASTOGENESIS; OSTEOLYSIS; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; REGULATORY MECHANISM; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UPREGULATION;

ARTHRITIS; BONE; NRF2; OSTEOCLAST; PERIODONTAL DISEASE; REACTIVE OXYGEN SPECIES (ROS);

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL DIFFERENTIATION; CELL LINE; CYTOSKELETAL PROTEINS; GENE EXPRESSION REGULATION; LIPOPOLYSACCHARIDES; MACROPHAGES, PERITONEAL; MICE; NF-E2-RELATED FACTOR 2; OSTEOCLASTS; OSTEOLYSIS; RANK LIGAND; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84881399163     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.478545     Document Type: Article

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