메뉴 건너뛰기




Volumn 49, Issue 5, 2014, Pages 563-573

Deferoxamine promotes osteoblastic differentiation in human periodontal ligament cells via the nuclear factor erythroid 2-related factor-mediated antioxidant signaling pathway

Author keywords

Antioxidant; Deferoxamine; Iron chelator; Nuclear factor erythroid 2 related factor; Osteoblastic differentiation; Periodontal ligament cells

Indexed keywords

ACETYLCYSTEINE; ALPHA TOCOPHEROL; BUTHIONINE SULFOXIMINE; CALCIUM; DEFEROXAMINE; ENZYME INHIBITOR; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MALEIC ACID DERIVATIVE; MALEIC ACID DIETHYL ESTER; NFE2L2 PROTEIN, HUMAN; REACTIVE OXYGEN METABOLITE; SCAVENGER; SIDEROPHORE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR NRF2;

EID: 84908566334     PISSN: 00223484     EISSN: 16000765     Source Type: Journal    
DOI: 10.1111/jre.12136     Document Type: Article
Times cited : (42)

References (65)
  • 1
    • 0037376489 scopus 로고    scopus 로고
    • Regulatory mechanisms of periodontal regeneration
    • Shimono M, Ishikawa T, Ishikawa H et al. Regulatory mechanisms of periodontal regeneration. Microsc Res Tech 2003;60:491-502.
    • (2003) Microsc Res Tech , vol.60 , pp. 491-502
    • Shimono, M.1    Ishikawa, T.2    Ishikawa, H.3
  • 2
    • 0037215658 scopus 로고    scopus 로고
    • Ascorbic acid induces collagenase-1 in human periodontal ligament cells but not in MC3T3-E1 osteoblast-like cells: potential association between collagenase expression and changes in alkaline phosphatase phenotype
    • Shiga M, Kapila YL, Zhang Q, Hayami T, Kapila S. Ascorbic acid induces collagenase-1 in human periodontal ligament cells but not in MC3T3-E1 osteoblast-like cells: potential association between collagenase expression and changes in alkaline phosphatase phenotype. J Bone Miner Res 2003;18:67-77.
    • (2003) J Bone Miner Res , vol.18 , pp. 67-77
    • Shiga, M.1    Kapila, Y.L.2    Zhang, Q.3    Hayami, T.4    Kapila, S.5
  • 4
    • 0033278059 scopus 로고    scopus 로고
    • Recombinant human bone morphogenetic protein-2 stimulates osteoblast differentiation in cells isolated from human periodontal ligament
    • Kobayashi M, Takiguchi T, Suzuki R et al. Recombinant human bone morphogenetic protein-2 stimulates osteoblast differentiation in cells isolated from human periodontal ligament. J Dent Res 1999;78:1624-1633.
    • (1999) J Dent Res , vol.78 , pp. 1624-1633
    • Kobayashi, M.1    Takiguchi, T.2    Suzuki, R.3
  • 5
    • 3042615398 scopus 로고    scopus 로고
    • Role of ascorbic acid in periodontal ligament cell differentiation
    • Ishikawa S, Iwasaki K, Komaki M, Ishikawa I. Role of ascorbic acid in periodontal ligament cell differentiation. J Periodontol 2004;75:709-716.
    • (2004) J Periodontol , vol.75 , pp. 709-716
    • Ishikawa, S.1    Iwasaki, K.2    Komaki, M.3    Ishikawa, I.4
  • 6
    • 43049103024 scopus 로고    scopus 로고
    • Effect of estrogen receptor beta on the osteoblastic differentiation function of human periodontal ligament cells
    • Liang L, Yu JF, Wang Y, Wang G, Ding Y. Effect of estrogen receptor beta on the osteoblastic differentiation function of human periodontal ligament cells. Arch Oral Biol 2008;53:553-557.
    • (2008) Arch Oral Biol , vol.53 , pp. 553-557
    • Liang, L.1    Yu, J.F.2    Wang, Y.3    Wang, G.4    Ding, Y.5
  • 7
    • 58149263901 scopus 로고    scopus 로고
    • IL-6 induces osteoblastic differentiation of periodontal ligament cells
    • Iwasaki K, Komaki M, Mimori K, Leon E, Izumi Y, Ishikawa I. IL-6 induces osteoblastic differentiation of periodontal ligament cells. J Dent Res 2008;87: 937-942.
    • (2008) J Dent Res , vol.87 , pp. 937- 942
    • Iwasaki, K.1    Komaki, M.2    Mimori, K.3    Leon, E.4    Izumi, Y.5    Ishikawa, I.6
  • 8
    • 33748594198 scopus 로고    scopus 로고
    • Effect of F-spondin on cementoblastic differentiation of human periodontal ligament cells
    • Kitagawa M, Kudo Y, Iizuka S et al. Effect of F-spondin on cementoblastic differentiation of human periodontal ligament cells. Biochem Biophys Res Commun 2006;349:1050-1056.
    • (2006) Biochem Biophys Res Commun , vol.349 , pp. 1050-1056
    • Kitagawa, M.1    Kudo, Y.2    Iizuka, S.3
  • 9
    • 69149091631 scopus 로고    scopus 로고
    • Nitric oxide modulates osteoblastic differentiation with heme oxygenase-1 via the mitogen activated protein kinase and nuclear factor-kappa B pathways in human periodontal ligament cells
    • Lee SK, Choi HI, Yang YS et al. Nitric oxide modulates osteoblastic differentiation with heme oxygenase-1 via the mitogen activated protein kinase and nuclear factor-kappa B pathways in human periodontal ligament cells. Bio pharm Bull 2009;32:1328-1334.
    • (2009) Bio pharm Bull , vol.32 , pp. 1328-1334
    • Lee, S.K.1    Choi, H.I.2    Yang, Y.S.3
  • 10
    • 61349193104 scopus 로고    scopus 로고
    • Effects of substance P on osteoblastic differentiation and heme oxygenase-1 in human periodontal ligament cells
    • Kook YA, Lee SK, Son DH et al. Effects of substance P on osteoblastic differentiation and heme oxygenase-1 in human periodontal ligament cells. Cell Biol Int 2009;33:424-428.
    • (2009) Cell Biol Int , vol.33 , pp. 424-428
    • Kook, Y.A.1    Lee, S.K.2    Son, D.H.3
  • 11
    • 80054921563 scopus 로고    scopus 로고
    • The role of sirtuin 1 in osteoblastic differentiation in human periodontal ligament cells
    • Lee YM, Shin SI, Shin KS, Lee YR, Park BH, Kim EC. The role of sirtuin 1 in osteoblastic differentiation in human periodontal ligament cells. J Periodontal Res 2011;46:712-721.
    • (2011) J Periodontal Res , vol.46 , pp. 712-721
    • Lee, Y.M.1    Shin, S.I.2    Shin, K.S.3    Lee, Y.R.4    Park, B.H.5    Kim, E.C.6
  • 12
    • 2042546096 scopus 로고    scopus 로고
    • Balancing acts: molecular control of mammalian iron metabolism
    • Hentze MW, Muckenthaler MU, Andrews NC. Balancing acts: molecular control of mammalian iron metabolism. Cell 2004;117:285-297.
    • (2004) Cell , vol.117 , pp. 285-297
    • Hentze, M.W.1    Muckenthaler, M.U.2    Andrews, N.C.3
  • 13
    • 9544254855 scopus 로고    scopus 로고
    • Variation of long-lived free radicals responsible for the EPR native signal in bone of aged or diseased human females and ovariectomized adult rats
    • Kenner GH, Brik AB, Liu G et al. Variation of long-lived free radicals responsible for the EPR native signal in bone of aged or diseased human females and ovariectomized adult rats. Radiat Meas 2005;39:255-262.
    • (2005) Radiat Meas , vol.39 , pp. 255-262
    • Kenner, G.H.1    Brik, A.B.2    Liu, G.3
  • 14
    • 33745405978 scopus 로고    scopus 로고
    • Age-associated iron accumulation in bone: implications for postmenopausal osteoporosis and a new target for prevention and treatment by chelation
    • Liu G, Men P, Kenner GH, Miller SC. Age-associated iron accumulation in bone: implications for postmenopausal osteoporosis and a new target for prevention and treatment by chelation. Biometals 2006;19:245-251.
    • (2006) Biometals , vol.19 , pp. 245-251
    • Liu, G.1    Men, P.2    Kenner, G.H.3    Miller, S.C.4
  • 15
    • 0034651775 scopus 로고    scopus 로고
    • Long-term outcome of continuous 24-hour deferoxamine infusion via indwelling intra-venous catheters in high-risk beta-thalassemia
    • Davis BA, Porter JB. Long-term outcome of continuous 24-hour deferoxamine infusion via indwelling intra-venous catheters in high-risk beta-thalassemia. Blood 2000;95:1229-1236.
    • (2000) Blood , vol.95 , pp. 1229-1236
    • Davis, B.A.1    Porter, J.B.2
  • 16
    • 70349220913 scopus 로고    scopus 로고
    • Prolyl hydroxylase inhibitors increase neoangiogenesis and callus formation following femur fracture in mice
    • Shen X, Wan C, Ramaswamy G et al. Prolyl hydroxylase inhibitors increase neoangiogenesis and callus formation following femur fracture in mice. J Orthop Res 2009;27:1298-1305.
    • (2009) J Orthop Res , vol.27 , pp. 1298-1305
    • Shen, X.1    Wan, C.2    Ramaswamy, G.3
  • 18
    • 84859433320 scopus 로고    scopus 로고
    • Deferoxamine reverses radiation induced hypovascularity during bone regeneration and repair in the murine mandible
    • Farberg AS, Jing XL, Monson LA et al. Deferoxamine reverses radiation induced hypovascularity during bone regeneration and repair in the murine mandible. Bone 2012;50:1184-1187.
    • (2012) Bone , vol.50 , pp. 1184-1187
    • Farberg, A.S.1    Jing, X.L.2    Monson, L.A.3
  • 19
    • 0031001278 scopus 로고    scopus 로고
    • Iron-chelating therapy and the treatment of thalassemia
    • Olivieri NF, Brittenham GM. Iron-chelating therapy and the treatment of thalassemia. Blood 1997;89:739-761.
    • (1997) Blood , vol.89 , pp. 739-761
    • Olivieri, N.F.1    Brittenham, G.M.2
  • 20
    • 0031957505 scopus 로고    scopus 로고
    • Effect of desferrioxamine and deferiprone (L1) on the proliferation of MG-63 bone cells and on phosphatase alkaline activity
    • Naves Díaz ML, Elorriaga R, Canteros A, Cannata Andía JB. Effect of desferrioxamine and deferiprone (L1) on the proliferation of MG-63 bone cells and on phosphatase alkaline activity. Nephrol Dial Transplant 1998; 13(suppl 3): 23-28.
    • (1998) Nephrol Dial Transplant , vol.13 , pp. 23-28
    • Naves Díaz, M.L.1    Elorriaga, R.2    Canteros, A.3    Cannata Andía, J.B.4
  • 21
    • 77951243024 scopus 로고    scopus 로고
    • Iron chelator deferoxamine alters iron-regulatory genes and proteins and suppresses osteoblast phenotype in fetal rat calvaria cells
    • Messer JG, Cooney PT, Kipp DE. Iron chelator deferoxamine alters iron-regulatory genes and proteins and suppresses osteoblast phenotype in fetal rat calvaria cells. Bone 2010;46:1408-1415.
    • (2010) Bone , vol.46 , pp. 1408-1415
    • Messer, J.G.1    Cooney, P.T.2    Kipp, D.E.3
  • 22
    • 42449094897 scopus 로고    scopus 로고
    • Promotion of osteogenesis through b-catenin signaling by desferrioxamine
    • Qu ZH, Zhang XL, Tang TT, Dai KR. Promotion of osteogenesis through b-catenin signaling by desferrioxamine. Biochem Biophys Res Commun 2008;370:332-337.
    • (2008) Biochem Biophys Res Commun , vol.370 , pp. 332-337
    • Qu, Z.H.1    Zhang, X.L.2    Tang, T.T.3    Dai, K.R.4
  • 23
    • 14044254798 scopus 로고    scopus 로고
    • Molecular mechanisms activating the Nrf2-Keap1 pathway of antioxidant gene regulation
    • Kobayashi M, Yamamoto M. Molecular mechanisms activating the Nrf2-Keap1 pathway of antioxidant gene regulation. Antioxid Redox Signal 2005;7:385-394.
    • (2005) Antioxid Redox Signal , vol.7 , pp. 385-394
    • Kobayashi, M.1    Yamamoto, M.2
  • 24
    • 0023626933 scopus 로고
    • Improvement of postischemic myocardial function and metabolism induced by administration of deferoxamine at the time of reflow: the role of iron in the pathogenesis of reperfusion injury
    • Ambrosio G, Zweier JL, Jacobus WE, Weisfeldt ML, Flaherty JT. Improvement of postischemic myocardial function and metabolism induced by administration of deferoxamine at the time of reflow: the role of iron in the pathogenesis of reperfusion injury. Circulation 1987;76:906-915.
    • (1987) Circulation , vol.76 , pp. 906-915
    • Ambrosio, G.1    Zweier, J.L.2    Jacobus, W.E.3    Weisfeldt, M.L.4    Flaherty, J.T.5
  • 25
    • 0034873185 scopus 로고    scopus 로고
    • Reactive oxygen species as intracellular messengers during cell growth and differentiation
    • Sauer H, Wartenberg M, Hescheler J. Reactive oxygen species as intracellular messengers during cell growth and differentiation. Cell Physiol Biochem 2001;11:173-186.
    • (2001) Cell Physiol Biochem , vol.11 , pp. 173-186
    • Sauer, H.1    Wartenberg, M.2    Hescheler, J.3
  • 26
    • 33644790434 scopus 로고    scopus 로고
    • Desferoxamine and ethyl-3,4-dihydroxybenzoate protect myocardium by activating NOS and generating mitochondrial ROS
    • Philipp S, Cui L, Ludolph B et al. Desferoxamine and ethyl-3, 4-dihydroxybenzoate protect myocardium by activating NOS and generating mitochondrial ROS. Am J Physiol Heart Circ Physiol 2006;290:H450-H457.
    • (2006) Am J Physiol Heart Circ Physiol , vol.290 , pp. H450-H457
    • Philipp, S.1    Cui, L.2    Ludolph, B.3
  • 27
    • 33846426804 scopus 로고    scopus 로고
    • Iron chelation study in a normal human hepatocyte cell line suggests that tumor necrosis factor receptor-associated protein 1 (TRAP1) regulates production of reactive oxygen species
    • Im CN, Lee JS, Zheng Y, Seo JS. Iron chelation study in a normal human hepatocyte cell line suggests that tumor necrosis factor receptor-associated protein 1 (TRAP1) regulates production of reactive oxygen species. J Cell Biochem 2007;100:474-486.
    • (2007) J Cell Biochem , vol.100 , pp. 474-486
    • Im, C.N.1    Lee, J.S.2    Zheng, Y.3    Seo, J.S.4
  • 28
    • 33646073995 scopus 로고    scopus 로고
    • Iron chelator induces THP-1 cell differentiation potentially by modulating intracellular glutathione levels
    • Seo GS, Lee SH, Choi SC et al. Iron chelator induces THP-1 cell differentiation potentially by modulating intracellular glutathione levels. Free Radic Biol Med 2006;40:1502-1512.
    • (2006) Free Radic Biol Med , vol.40 , pp. 1502-1512
    • Seo, G.S.1    Lee, S.H.2    Choi, S.C.3
  • 29
    • 39149140706 scopus 로고    scopus 로고
    • Statin-induced heme oxygenase-1 increases NF-kappaB activation and oxygen radical production in cultured neuronal cells exposed to lipopolysaccharide
    • Hsieh CH, Jeng SF, Hsieh MW et al. Statin-induced heme oxygenase-1 increases NF-kappaB activation and oxygen radical production in cultured neuronal cells exposed to lipopolysaccharide. Toxicol Sci 2008;102:150-159.
    • (2008) Toxicol Sci , vol.102 , pp. 150-159
    • Hsieh, C.H.1    Jeng, S.F.2    Hsieh, M.W.3
  • 30
    • 33644620272 scopus 로고    scopus 로고
    • Establishing and characterizing human periodontal ligament fibroblasts immortalized by SV40T-antigen and hTERT gene transfer
    • Fujii S, Maeda H, Wada N, Kano Y, Akamine A. Establishing and characterizing human periodontal ligament fibroblasts immortalized by SV40T-antigen and hTERT gene transfer. Cell Tissue Res 2002;324:117-125.
    • (2002) Cell Tissue Res , vol.324 , pp. 117-125
    • Fujii, S.1    Maeda, H.2    Wada, N.3    Kano, Y.4    Akamine, A.5
  • 31
    • 3042749378 scopus 로고    scopus 로고
    • Investigation of multipotent postnatal stem cells from human periodontal ligament
    • Seo BM, Miura M, Gronthos S et al. Investigation of multipotent postnatal stem cells from human periodontal ligament. Lancet 2004;364:149-155.
    • (2004) Lancet , vol.364 , pp. 149-155
    • Seo, B.M.1    Miura, M.2    Gronthos, S.3
  • 32
    • 0030589628 scopus 로고    scopus 로고
    • Adhesion-growth factor interactions during differentiation: an integrated biological response
    • Sastry SK, Horwitz AF. Adhesion-growth factor interactions during differentiation: an integrated biological response. Dev Biol 1996;180:455-467.
    • (1996) Dev Biol , vol.180 , pp. 455-467
    • Sastry, S.K.1    Horwitz, A.F.2
  • 34
    • 0035500487 scopus 로고    scopus 로고
    • Cellular senescence as a tumor-suppressor mechanism
    • Campisi J. Cellular senescence as a tumor-suppressor mechanism. Trend Cell Biol 2001;11(suppl 1):27-31.
    • (2001) Trend Cell Biol , vol.11 , pp. 27-31
    • Campisi, J.1
  • 35
    • 33751510436 scopus 로고    scopus 로고
    • Dexamethasone's enhancement of osteoblastic markers in human periodontal ligament cells is associated with inhibition of collagenase expression
    • Hayami T, Zhang Q, Kapila Y, Kapila S. Dexamethasone's enhancement of osteoblastic markers in human periodontal ligament cells is associated with inhibition of collagenase expression. Bone 2007;40:93-104.
    • (2007) Bone , vol.40 , pp. 93-104
    • Hayami, T.1    Zhang, Q.2    Kapila, Y.3    Kapila, S.4
  • 36
    • 0029000158 scopus 로고
    • Markers of bone metabolism
    • Cormier C. Markers of bone metabolism. Curr Opin Rheumatol 1995;7:243-248.
    • (1995) Curr Opin Rheumatol , vol.7 , pp. 243-248
    • Cormier, C.1
  • 37
  • 40
    • 4344638224 scopus 로고    scopus 로고
    • Glutathione depletion impairs myogenic differentiation of murine skeletal muscle C2C12 cells through sustained NF-kappaB activation
    • Ardite E, Barbera JA, Roca J, Fernández-Checa JC. Glutathione depletion impairs myogenic differentiation of murine skeletal muscle C2C12 cells through sustained NF-kappaB activation. Am J Pathol 2004;165:719-728.
    • (2004) Am J Pathol , vol.165 , pp. 719-728
    • Ardite, E.1    Barbera, J.A.2    Roca, J.3    Fernández-Checa, J.C.4
  • 41
    • 77957559690 scopus 로고    scopus 로고
    • Cellular antioxidant levels influence muscle stem cell therapy
    • Drowley L, Okada M, Beckman S et al. Cellular antioxidant levels influence muscle stem cell therapy. Mol Ther 2010;18:1865-1873.
    • (2010) Mol Ther , vol.18 , pp. 1865-1873
    • Drowley, L.1    Okada, M.2    Beckman, S.3
  • 42
    • 67349275687 scopus 로고    scopus 로고
    • Differential expression of glutathione S-transferases P1-1 and A1-1 at protein and mRNA levels in hepatocytes derived from human bone marrow mesenchymal stem cells
    • Allameh A, Esmaeli S, Kazemnejad S, Soleimani M. Differential expression of glutathione S-transferases P1-1 and A1-1 at protein and mRNA levels in hepatocytes derived from human bone marrow mesenchymal stem cells. Toxicol In Vitro 2009;23:674-679.
    • (2009) Toxicol In Vitro , vol.23 , pp. 674-679
    • Allameh, A.1    Esmaeli, S.2    Kazemnejad, S.3    Soleimani, M.4
  • 44
    • 84873139186 scopus 로고    scopus 로고
    • Role of GSH/GSSG redox couple in osteogenic activity and osteoclastogenic markers of human osteoblast-like SaOS-2 cells
    • Romagnoli C, Marcucci G, Favilli F et al. Role of GSH/GSSG redox couple in osteogenic activity and osteoclastogenic markers of human osteoblast-like SaOS-2 cells. FEBS J 2013;280:867-879.
    • (2013) FEBS J , vol.280 , pp. 867-879
    • Romagnoli, C.1    Marcucci, G.2    Favilli, F.3
  • 45
    • 20144365876 scopus 로고    scopus 로고
    • Nox 2 stimulates muscle differentiation via NF-kappaB/iNOS pathway
    • Piao YJ, Seo YH, Hong F et al. Nox 2 stimulates muscle differentiation via NF-kappaB/iNOS pathway. Free Radic Biol Med 2005;38:989-1001.
    • (2005) Free Radic Biol Med , vol.38 , pp. 989-1001
    • Piao, Y.J.1    Seo, Y.H.2    Hong, F.3
  • 46
    • 34047146388 scopus 로고    scopus 로고
    • Suppressing phosphatidylcholine-specific phospholipase C and elevating ROS level, NADPH oxidase activity and Rb level induced neuronal differentiation in mesenchymal stem cells
    • Wang N, Xie K, Huo S, Zhao J, Zhang S, Miao J. Suppressing phosphatidylcholine-specific phospholipase C and elevating ROS level, NADPH oxidase activity and Rb level induced neuronal differentiation in mesenchymal stem cells. J Cell Biochem 2007;100:1548-1557.
    • (2007) J Cell Biochem , vol.100 , pp. 1548-1557
    • Wang, N.1    Xie, K.2    Huo, S.3    Zhao, J.4    Zhang, S.5    Miao, J.6
  • 47
    • 77952895127 scopus 로고    scopus 로고
    • Static electromagnetic fields induce vasculogenesis and chondro-osteogenesis of mouse embryonic stem cells by reactive oxygen species-mediated up-regulation of vascular endothelial growth factor
    • Bekhite MM, Finkensieper A, Abou-Zaid FA et al. Static electromagnetic fields induce vasculogenesis and chondro-osteogenesis of mouse embryonic stem cells by reactive oxygen species-mediated up-regulation of vascular endothelial growth factor. Stem Cells Dev 2010;19: 731-743.
    • (2010) Stem Cells Dev , vol.19 , pp. 731- 743
    • Bekhite, M.M.1    Finkensieper, A.2    Abou-Zaid, F.A.3
  • 48
    • 80053904684 scopus 로고    scopus 로고
    • Mitochondrial complex III ROS regulate adipocyte differentiation
    • Tormos KV, Anso E, Hamanaka RB et al. Mitochondrial complex III ROS regulate adipocyte differentiation. Cell Metab 2011;14:537-544.
    • (2011) Cell Metab , vol.14 , pp. 537-544
    • Tormos, K.V.1    Anso, E.2    Hamanaka, R.B.3
  • 49
    • 0026343403 scopus 로고
    • Glutathione deficiency produced by inhibition of its synthesis, and its reversal; applications in research and therapy
    • Meister A. Glutathione deficiency produced by inhibition of its synthesis, and its reversal; applications in research and therapy. Pharmacol Ther 1991;51: 155-194.
    • (1991) Pharmacol Ther , vol.51 , pp. 155- 194
    • Meister, A.1
  • 50
    • 0024394697 scopus 로고
    • The antioxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide, an hypochlorous acid
    • Aruoma OI, Halliwell B, Hoey BM, Bulter J. The antioxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide, an hypochlorous acid. Free Radic Biol Med 1989;6:593-597.
    • (1989) Free Radic Biol Med , vol.6 , pp. 593-597
    • Aruoma, O.I.1    Halliwell, B.2    Hoey, B.M.3    Bulter, J.4
  • 52
    • 0028136950 scopus 로고
    • Inhibition of the differentiation of human myeloid cell lines by redox changes induced through glutathione depletion
    • Esposito F, Agosti V, Morrone G et al. Inhibition of the differentiation of human myeloid cell lines by redox changes induced through glutathione depletion. Biochem J 1994;301:649-653.
    • (1994) Biochem J , vol.301 , pp. 649-653
    • Esposito, F.1    Agosti, V.2    Morrone, G.3
  • 53
    • 68749109409 scopus 로고    scopus 로고
    • Effects of nicotine on antioxidant defense enzymes and RANKL expression in human periodontal ligament cells
    • Lee HJ, Pi SH, Kim Y et al. Effects of nicotine on antioxidant defense enzymes and RANKL expression in human periodontal ligament cells. J Periodontol 2009;80:1281-1288.
    • (2009) J Periodontol , vol.80 , pp. 1281-1288
    • Lee, H.J.1    Pi, S.H.2    Kim, Y.3
  • 54
    • 47049084916 scopus 로고    scopus 로고
    • Hydrogen peroxide induces heme oxygenase-1 and dentin sialophosphoprotein mRNA in human pulp cells
    • Min KS, Lee HJ, Kim HO et al. Hydrogen peroxide induces heme oxygenase-1 and dentin sialophosphoprotein mRNA in human pulp cells. J Endod 2008;34:983-989.
    • (2008) J Endod , vol.34 , pp. 983-989
    • Min, K.S.1    Lee, H.J.2    Kim, H.O.3
  • 55
    • 40349087135 scopus 로고    scopus 로고
    • N-acetylcysteine stimulate osteoblastic differentiation of mouse calvarial cells
    • Jun JH, Lee SH, Kwak HB et al. N-acetylcysteine stimulate osteoblastic differentiation of mouse calvarial cells. J Cell Biochem 2008;103:1246-1255.
    • (2008) J Cell Biochem , vol.103 , pp. 1246-1255
    • Jun, J.H.1    Lee, S.H.2    Kwak, H.B.3
  • 56
    • 34147153241 scopus 로고    scopus 로고
    • Iron chelation acutely stimulates fetal human intestinal cell production of IL-6 and VEGF while decreasing HGF: the roles of p38, ERK, and JNK MAPK signaling
    • Markel TA, Crisostomo PR, Wang M et al. Iron chelation acutely stimulates fetal human intestinal cell production of IL-6 and VEGF while decreasing HGF: the roles of p38, ERK, and JNK MAPK signaling. Am J Physiol Gastrointest Liver Physiol 2007;292:G958-G963.
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.292 , pp. G958-G963
    • Markel, T.A.1    Crisostomo, P.R.2    Wang, M.3
  • 57
    • 47249110726 scopus 로고    scopus 로고
    • Iron chelator differentially activates macrophage inflammatory protein-3alpha/CCL20 in immortalized and malignant human oral keratinocytes
    • Lee SK, Lee J, Min SK et al. Iron chelator differentially activates macrophage inflammatory protein-3alpha/CCL20 in immortalized and malignant human oral keratinocytes. Arch Oral Biol 2008;53: 801-809.
    • (2008) Arch Oral Biol , vol.53 , pp. 801-809
    • Lee, S.K.1    Lee, J.2    Min, S.K.3
  • 58
    • 36348987278 scopus 로고    scopus 로고
    • Differential regulation of iron chelator-induced IL-8 synthesis via MAP kinase and NF-kappaB in immortalized and malignant oral keratinocytes
    • Lee HJ, Lee J, Lee SK, Lee SK, Kim EC. Differential regulation of iron chelator-induced IL-8 synthesis via MAP kinase and NF-kappaB in immortalized and malignant oral keratinocytes. BMC Cancer 2007;7:176.
    • (2007) BMC Cancer , vol.7 , pp. 176
    • Lee, H.J.1    Lee, J.2    Lee, S.K.3    Lee, S.K.4    Kim, E.C.5
  • 59
    • 35648934051 scopus 로고    scopus 로고
    • N-acetyicysteine prevents lps-lnduced pro-inflammatory cytokines and mmp2 production in gingival fibroblasts
    • Kim DY, Jun JH, Lee HL et al. N-acetyicysteine prevents lps-lnduced pro-inflammatory cytokines and mmp2 production in gingival fibroblasts. Arch Pharm Res 2007;30:1283-1292.
    • (2007) Arch Pharm Res , vol.30 , pp. 1283-1292
    • Kim, D.Y.1    Jun, J.H.2    Lee, H.L.3
  • 60
    • 84860394100 scopus 로고    scopus 로고
    • Carmustine induces ERK- and JNK-dependent cell death of neuronally-differentiated PC12 cells via generation of reactive oxygen species
    • An JM, Kim SS, Rhie JH, Shin DM, Seo SR, Seo JT. Carmustine induces ERK- and JNK-dependent cell death of neuronally-differentiated PC12 cells via generation of reactive oxygen species. Toxicol In Vitro 2011;25:1359-1365.
    • (2011) Toxicol In Vitro , vol.25 , pp. 1359-1365
    • An, J.M.1    Kim, S.S.2    Rhie, J.H.3    Shin, D.M.4    Seo, S.R.5    Seo, J.T.6
  • 61
    • 0029969860 scopus 로고    scopus 로고
    • Arsenic induces oxidant stress and NF-KB activation in cultured aortic endothelial cells
    • Barchowsky A, Dudek EJ, Treadwell MD, Wetterhahn KE. Arsenic induces oxidant stress and NF-KB activation in cultured aortic endothelial cells. Free Radic Biol Med 1996;21:783-790.
    • (1996) Free Radic Biol Med , vol.21 , pp. 783-790
    • Barchowsky, A.1    Dudek, E.J.2    Treadwell, M.D.3    Wetterhahn, K.E.4
  • 62
    • 33847633373 scopus 로고    scopus 로고
    • Chalcone inhibits the activation of NF-kappaB and STAT3 in endothelial cells via endogenous electrophile
    • Liu YC, Hsieh CW, Wu CC, Wung BS. Chalcone inhibits the activation of NF-kappaB and STAT3 in endothelial cells via endogenous electrophile. Life Sci 2007;80:1420-1430.
    • (2007) Life Sci , vol.80 , pp. 1420-1430
    • Liu, Y.C.1    Hsieh, C.W.2    Wu, C.C.3    Wung, B.S.4
  • 63
    • 0036199273 scopus 로고    scopus 로고
    • Redox signaling-mediated regulation of lipopolysaccharide-induced proinflammatory cytokine biosynthesis in alveolar epithelial cells
    • Haddad JJ, Land SC. Redox signaling-mediated regulation of lipopolysaccharide-induced proinflammatory cytokine biosynthesis in alveolar epithelial cells. Antioxid Redox Signal 2002;4:179-193.
    • (2002) Antioxid Redox Signal , vol.4 , pp. 179-193
    • Haddad, J.J.1    Land, S.C.2
  • 64
    • 84863987317 scopus 로고    scopus 로고
    • New bone formation in a true bone ceramic scaffold loaded with desferrioxamine in the treatment of segmental bone defect: a preliminary study
    • Zhang W, Li G, Deng R, Deng L, Qiu S. New bone formation in a true bone ceramic scaffold loaded with desferrioxamine in the treatment of segmental bone defect: a preliminary study. J Orthop Sci 2012;17:289-298.
    • (2012) J Orthop Sci , vol.17 , pp. 289-298
    • Zhang, W.1    Li, G.2    Deng, R.3    Deng, L.4    Qiu, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.