-
1
-
-
84873691650
-
The Th17 pathway and inflammatory diseases of the intestines, lungs, and skin
-
Weaver, C. T., C. O. Elson, L. A. Fouser, and J. K. Kolls. 2013. The Th17 pathway and inflammatory diseases of the intestines, lungs, and skin. Annu. Rev. Pathol. 8: 477-512.
-
(2013)
Annu. Rev. Pathol.
, vol.8
, pp. 477-512
-
-
Weaver, C.T.1
Elson, C.O.2
Fouser, L.A.3
Kolls, J.K.4
-
2
-
-
84908658274
-
Th17 cells in central nervous system autoimmunity
-
Sie, C., T. Korn, and M. Mitsdoerffer. 2014. Th17 cells in central nervous system autoimmunity. Exp. Neurol. 262(Pt. A): 18-27.
-
(2014)
Exp. Neurol.
, vol.262
, pp. 18-27
-
-
Sie, C.1
Korn, T.2
Mitsdoerffer, M.3
-
3
-
-
78649689761
-
Signal transduction pathways and transcriptional regulation in Th17 cell differentiation
-
Hirahara, K., K. Ghoreschi, A. Laurence, X. P. Yang, Y. Kanno, and J. J. O'Shea. 2010. Signal transduction pathways and transcriptional regulation in Th17 cell differentiation. Cytokine Growth Factor Rev. 21: 425-434.
-
(2010)
Cytokine Growth Factor Rev.
, vol.21
, pp. 425-434
-
-
Hirahara, K.1
Ghoreschi, K.2
Laurence, A.3
Yang, X.P.4
Kanno, Y.5
O'Shea, J.J.6
-
4
-
-
84875610850
-
Recent advances in understanding the molecular mechanisms of the development and function of Th17 cells
-
Kurebayashi, Y., S. Nagai, A. Ikejiri, and S. Koyasu. 2013. Recent advances in understanding the molecular mechanisms of the development and function of Th17 cells. Genes Cells 18: 247-265.
-
(2013)
Genes Cells
, vol.18
, pp. 247-265
-
-
Kurebayashi, Y.1
Nagai, S.2
Ikejiri, A.3
Koyasu, S.4
-
5
-
-
84866934694
-
Targeting IL-17 and TH17 cells in chronic inflammation
-
Miossec, P., and J. K. Kolls. 2012. Targeting IL-17 and TH17 cells in chronic inflammation. Nat. Rev. Drug Discov. 11: 763-776.
-
(2012)
Nat. Rev. Drug Discov.
, vol.11
, pp. 763-776
-
-
Miossec, P.1
Kolls, J.K.2
-
6
-
-
84865772592
-
Small molecule inhibitors of RORγt: Targeting Th17 cells and other applications
-
Huh, J. R., and D. R. Littman. 2012. Small molecule inhibitors of RORγt: targeting Th17 cells and other applications. Eur. J. Immunol. 42: 2232-2237.
-
(2012)
Eur. J. Immunol.
, vol.42
, pp. 2232-2237
-
-
Huh, J.R.1
Littman, D.R.2
-
7
-
-
84898688169
-
Small-molecule RORγt antagonists inhibit T helper 17 cell transcriptional network by divergent mechanisms
-
Xiao, S., N. Yosef, J. Yang, Y. Wang, L. Zhou, C. Zhu, C. Wu, E. Baloglu, D. Schmidt, R. Ramesh, et al. 2014. Small-molecule RORγt antagonists inhibit T helper 17 cell transcriptional network by divergent mechanisms. Immunity 40: 477-489.
-
(2014)
Immunity
, vol.40
, pp. 477-489
-
-
Xiao, S.1
Yosef, N.2
Yang, J.3
Wang, Y.4
Zhou, L.5
Zhu, C.6
Wu, C.7
Baloglu, E.8
Schmidt, D.9
Ramesh, R.10
-
8
-
-
33748588423
-
The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells
-
Ivanov, I. I., B. S. McKenzie, L. Zhou, C. E. Tadokoro, A. Lepelley, J. J. Lafaille, D. J. Cua, and D. R. Littman. 2006. The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell 126: 1121-1133.
-
(2006)
Cell
, vol.126
, pp. 1121-1133
-
-
Ivanov, I.I.1
McKenzie, B.S.2
Zhou, L.3
Tadokoro, C.E.4
Lepelley, A.5
Lafaille, J.J.6
Cua, D.J.7
Littman, D.R.8
-
9
-
-
34249079176
-
Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells
-
Acosta-Rodriguez, E. V., L. Rivino, J. Geginat, D. Jarrossay, M. Gattorno, A. Lanzavecchia, F. Sallusto, and G. Napolitani. 2007. Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells. Nat. Immunol. 8: 639-646.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 639-646
-
-
Acosta-Rodriguez, E.V.1
Rivino, L.2
Geginat, J.3
Jarrossay, D.4
Gattorno, M.5
Lanzavecchia, A.6
Sallusto, F.7
Napolitani, G.8
-
10
-
-
34547734621
-
Phenotypic and functional features of human Th17 cells
-
Annunziato, F., L. Cosmi, V. Santarlasci, L. Maggi, F. Liotta, B. Mazzinghi, E. Parente, L. Filì, S. Ferri, F. Frosali, et al. 2007. Phenotypic and functional features of human Th17 cells. J. Exp. Med. 204: 1849-1861.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1849-1861
-
-
Annunziato, F.1
Cosmi, L.2
Santarlasci, V.3
Maggi, L.4
Liotta, F.5
Mazzinghi, B.6
Parente, E.7
Filì, L.8
Ferri, S.9
Frosali, F.10
-
11
-
-
40449141770
-
Human T cells that are able to produce IL-17 express the chemokine receptor CCR6
-
Singh, S. P., H. H. Zhang, J. F. Foley, M. N. Hedrick, and J. M. Farber. 2008. Human T cells that are able to produce IL-17 express the chemokine receptor CCR6. J. Immunol. 180: 214-221.
-
(2008)
J. Immunol.
, vol.180
, pp. 214-221
-
-
Singh, S.P.1
Zhang, H.H.2
Foley, J.F.3
Hedrick, M.N.4
Farber, J.M.5
-
12
-
-
40449111457
-
Human Th17 cells share major trafficking receptors with both polarized effector T cells and FOXP3+ regulatory T cells
-
Lim, H. W., J. Lee, P. Hillsamer, and C. H. Kim. 2008. Human Th17 cells share major trafficking receptors with both polarized effector T cells and FOXP3+ regulatory T cells. J. Immunol. 180: 122-129.
-
(2008)
J. Immunol.
, vol.180
, pp. 122-129
-
-
Lim, H.W.1
Lee, J.2
Hillsamer, P.3
Kim, C.H.4
-
14
-
-
84887512970
-
International Union of Basic and Clinical Pharmacology. [corrected]. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for atypical chemokine receptors
-
Bachelerie, F., A. Ben-Baruch, A. M. Burkhardt, C. Combadiere, J. M. Farber, G. J. Graham, R. Horuk, A. H. Sparre-Ulrich, M. Locati, A. D. Luster, et al. 2014. International Union of Basic and Clinical Pharmacology. [corrected]. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for atypical chemokine receptors. Pharmacol. Rev. 66: 1-79.
-
(2014)
Pharmacol. Rev.
, vol.66
, pp. 1-79
-
-
Bachelerie, F.1
Ben-Baruch, A.2
Burkhardt, A.M.3
Combadiere, C.4
Farber, J.M.5
Graham, G.J.6
Horuk, R.7
Sparre-Ulrich, A.H.8
Locati, M.9
Luster, A.D.10
-
15
-
-
36549019912
-
Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model
-
Hirota, K., H. Yoshitomi, M. Hashimoto, S. Maeda, S. Teradaira, N. Sugimoto, T. Yamaguchi, T. Nomura, H. Ito, T. Nakamura, et al. 2007. Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model. J. Exp. Med. 204: 2803-2812.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 2803-2812
-
-
Hirota, K.1
Yoshitomi, H.2
Hashimoto, M.3
Maeda, S.4
Teradaira, S.5
Sugimoto, N.6
Yamaguchi, T.7
Nomura, T.8
Ito, H.9
Nakamura, T.10
-
16
-
-
64849093508
-
Inhibition of CCR6 function reduces the severity of experimental autoimmune encephalomyelitis via effects on the priming phase of the immune response
-
Liston, A., R. E. Kohler, S. Townley, S. Haylock-Jacobs, I. Comerford, A. C. Caon, J. Webster, J. M. Harrison, J. Swann, I. Clark-Lewis, et al. 2009. Inhibition of CCR6 function reduces the severity of experimental autoimmune encephalomyelitis via effects on the priming phase of the immune response. J. Immunol. 182: 3121-3130.
-
(2009)
J. Immunol.
, vol.182
, pp. 3121-3130
-
-
Liston, A.1
Kohler, R.E.2
Townley, S.3
Haylock-Jacobs, S.4
Comerford, I.5
Caon, A.C.6
Webster, J.7
Harrison, J.M.8
Swann, J.9
Clark-Lewis, I.10
-
17
-
-
65249175159
-
C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE
-
Reboldi, A., C. Coisne, D. Baumjohann, F. Benvenuto, D. Bottinelli, S. Lira, A. Uccelli, A. Lanzavecchia, B. Engelhardt, and F. Sallusto. 2009. C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE. Nat. Immunol. 10: 514-523.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 514-523
-
-
Reboldi, A.1
Coisne, C.2
Baumjohann, D.3
Benvenuto, F.4
Bottinelli, D.5
Lira, S.6
Uccelli, A.7
Lanzavecchia, A.8
Engelhardt, B.9
Sallusto, F.10
-
18
-
-
68849104003
-
CCR6 is required for IL-23-induced psoriasis-like inflammation in mice
-
Hedrick, M. N., A. S. Lonsdorf, A. K. Shirakawa, C. C. Richard Lee, F. Liao, S. P. Singh, H. H. Zhang, A. Grinberg, P. E. Love, S. T. Hwang, and J. M. Farber. 2009. CCR6 is required for IL-23-induced psoriasis-like inflammation in mice. J. Clin. Invest. 119: 2317-2329.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 2317-2329
-
-
Hedrick, M.N.1
Lonsdorf, A.S.2
Shirakawa, A.K.3
Richard Lee, C.C.4
Liao, F.5
Singh, S.P.6
Zhang, H.H.7
Grinberg, A.8
Love, P.E.9
Hwang, S.T.10
Farber, J.M.11
-
19
-
-
22044439846
-
CCR6 regulates CD4+ T-cell-mediated acute graft-versus-host disease responses
-
Varona, R., V. Cadenas, L. Gómez, C. Martínez-A, and G. Márquez. 2005. CCR6 regulates CD4+ T-cell-mediated acute graft-versus-host disease responses. Blood 106: 18-26.
-
(2005)
Blood
, vol.106
, pp. 18-26
-
-
Varona, R.1
Cadenas, V.2
Gómez, L.3
Martínez-A, C.4
Márquez, G.5
-
20
-
-
44049104564
-
The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat
-
Manel, N., D. Unutmaz, and D. R. Littman. 2008. The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat. Nat. Immunol. 9: 641-649.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 641-649
-
-
Manel, N.1
Unutmaz, D.2
Littman, D.R.3
-
21
-
-
79953071769
-
Epigenetic modification of the human CCR6 gene is associated with stable CCR6 expression in T cells
-
Steinfelder, S., S. Floess, D. Engelbert, B. Haeringer, U. Baron, L. Rivino, B. Steckel, A. Gruetzkau, S. Olek, J. Geginat, et al. 2011. Epigenetic modification of the human CCR6 gene is associated with stable CCR6 expression in T cells. Blood 117: 2839-2846.
-
(2011)
Blood
, vol.117
, pp. 2839-2846
-
-
Steinfelder, S.1
Floess, S.2
Engelbert, D.3
Haeringer, B.4
Baron, U.5
Rivino, L.6
Steckel, B.7
Gruetzkau, A.8
Olek, S.9
Geginat, J.10
-
22
-
-
67651154105
-
Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells
-
Duhen, T., R. Geiger, D. Jarrossay, A. Lanzavecchia, and F. Sallusto. 2009. Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells. Nat. Immunol. 10: 857-863.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 857-863
-
-
Duhen, T.1
Geiger, R.2
Jarrossay, D.3
Lanzavecchia, A.4
Sallusto, F.5
-
23
-
-
0027411688
-
Fusion between a novel Krüppel-like zinc finger gene and the retinoic acid receptor-alpha locus due to a variant t(11;17) translocation associated with acute promyelocytic leukaemia
-
Chen, Z., N. J. Brand, A. Chen, S. J. Chen, J. H. Tong, Z. Y. Wang, S. Waxman, and A. Zelent. 1993. Fusion between a novel Krüppel-like zinc finger gene and the retinoic acid receptor-alpha locus due to a variant t(11;17) translocation associated with acute promyelocytic leukaemia. EMBO J. 12: 1161-1167.
-
(1993)
EMBO J.
, vol.12
, pp. 1161-1167
-
-
Chen, Z.1
Brand, N.J.2
Chen, A.3
Chen, S.J.4
Tong, J.H.5
Wang, Z.Y.6
Waxman, S.7
Zelent, A.8
-
24
-
-
84879207760
-
The promyelocytic leukemia zinc finger protein: Two decades of molecular oncology
-
Suliman, B. A., D. Xu, and B. R. Williams. 2012. The promyelocytic leukemia zinc finger protein: two decades of molecular oncology. Front Oncol 2: 74.
-
(2012)
Front Oncol
, vol.2
, pp. 74
-
-
Suliman, B.A.1
Xu, D.2
Williams, B.R.3
-
25
-
-
84887187453
-
Plzf drives MLL-fusion-mediated leukemogenesis specifically in long-term hematopoietic stem cells
-
Ono, R., M. Masuya, H. Nakajima, Y. Enomoto, E. Miyata, A. Nakamura, S. Ishii, K. Suzuki, F. Shibata-Minoshima, N. Katayama, et al. 2013. Plzf drives MLL-fusion-mediated leukemogenesis specifically in long-term hematopoietic stem cells. Blood 122: 1271-1283.
-
(2013)
Blood
, vol.122
, pp. 1271-1283
-
-
Ono, R.1
Masuya, M.2
Nakajima, H.3
Enomoto, Y.4
Miyata, E.5
Nakamura, A.6
Ishii, S.7
Suzuki, K.8
Shibata-Minoshima, F.9
Katayama, N.10
-
26
-
-
66149154321
-
The PRC1 Polycomb group complex interacts with PLZF/RARA to mediate leukemic transformation
-
Boukarabila, H., A. J. Saurin, E. Batsché, N. Mossadegh, M. van Lohuizen, A. P. Otte, J. Pradel, C. Muchardt, M. Sieweke, and E. Duprez. 2009. The PRC1 Polycomb group complex interacts with PLZF/RARA to mediate leukemic transformation. Genes Dev. 23: 1195-1206.
-
(2009)
Genes Dev.
, vol.23
, pp. 1195-1206
-
-
Boukarabila, H.1
Saurin, A.J.2
Batsché, E.3
Mossadegh, N.4
Van Lohuizen, M.5
Otte, A.P.6
Pradel, J.7
Muchardt, C.8
Sieweke, M.9
Duprez, E.10
-
27
-
-
69749125286
-
PLZF is a regulator of homeostatic and cytokine-induced myeloid development
-
Doulatov, S., F. Notta, K. L. Rice, L. Howell, A. Zelent, J. D. Licht, and J. E. Dick. 2009. PLZF is a regulator of homeostatic and cytokine-induced myeloid development. Genes Dev. 23: 2076-2087.
-
(2009)
Genes Dev.
, vol.23
, pp. 2076-2087
-
-
Doulatov, S.1
Notta, F.2
Rice, K.L.3
Howell, L.4
Zelent, A.5
Licht, J.D.6
Dick, J.E.7
-
28
-
-
84899448933
-
A committed precursor to innate lymphoid cells
-
Constantinides, M. G., B. D. McDonald, P. A. Verhoef, and A. Bendelac. 2014. A committed precursor to innate lymphoid cells. Nature 508: 397-401.
-
(2014)
Nature
, vol.508
, pp. 397-401
-
-
Constantinides, M.G.1
McDonald, B.D.2
Verhoef, P.A.3
Bendelac, A.4
-
29
-
-
50049084627
-
The BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions
-
Kovalovsky, D., O. U. Uche, S. Eladad, R. M. Hobbs, W. Yi, E. Alonzo, K. Chua, M. Eidson, H. J. Kim, J. S. Im, et al. 2008. The BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions. Nat. Immunol. 9: 1055-1064.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 1055-1064
-
-
Kovalovsky, D.1
Uche, O.U.2
Eladad, S.3
Hobbs, R.M.4
Yi, W.5
Alonzo, E.6
Chua, K.7
Eidson, M.8
Kim, H.J.9
Im, J.S.10
-
30
-
-
68149108582
-
TCR-inducible PLZF transcription factor required for innate phenotype of a subset of gammadelta T cells with restricted TCR diversity
-
Kreslavsky, T., A. K. Savage, R. Hobbs, F. Gounari, R. Bronson, P. Pereira, P. P. Pandolfi, A. Bendelac, and H. von Boehmer. 2009. TCR-inducible PLZF transcription factor required for innate phenotype of a subset of gammadelta T cells with restricted TCR diversity. Proc. Natl. Acad. Sci. USA 106: 12453-12458.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 12453-12458
-
-
Kreslavsky, T.1
Savage, A.K.2
Hobbs, R.3
Gounari, F.4
Bronson, R.5
Pereira, P.6
Pandolfi, P.P.7
Bendelac, A.8
Von Boehmer, H.9
-
31
-
-
51349121407
-
The transcription factor PLZF directs the effector program of the NKT cell lineage
-
Savage, A. K., M. G. Constantinides, J. Han, D. Picard, E. Martin, B. Li, O. Lantz, and A. Bendelac. 2008. The transcription factor PLZF directs the effector program of the NKT cell lineage. Immunity 29: 391-403.
-
(2008)
Immunity
, vol.29
, pp. 391-403
-
-
Savage, A.K.1
Constantinides, M.G.2
Han, J.3
Picard, D.4
Martin, E.5
Li, B.6
Lantz, O.7
Bendelac, A.8
-
32
-
-
80051885764
-
Genome-wide analyses of transcription factor GATA3-mediated gene regulation in distinct T cell types
-
Wei, G., B. J. Abraham, R. Yagi, R. Jothi, K. Cui, S. Sharma, L. Narlikar, D. L. Northrup, Q. Tang, W. E. Paul, et al. 2011. Genome-wide analyses of transcription factor GATA3-mediated gene regulation in distinct T cell types. Immunity 35: 299-311.
-
(2011)
Immunity
, vol.35
, pp. 299-311
-
-
Wei, G.1
Abraham, B.J.2
Yagi, R.3
Jothi, R.4
Cui, K.5
Sharma, S.6
Narlikar, L.7
Northrup, D.L.8
Tang, Q.9
Paul, W.E.10
-
33
-
-
80052432708
-
Altered development of NKT cells, gammadelta T cells, CD8 T cells and NK cells in a PLZF deficient patient
-
Available at
-
Eidson, M., J. Wahlstrom, A. M. Beaulieu, B. Zaidi, S. E. Carsons, P. K. Crow, J. Yuan, J. D. Wolchok, B. Horsthemke, D. Wieczorek, and D. B. Sant'Angelo. 2011. Altered development of NKT cells, gammadelta T cells, CD8 T cells and NK cells in a PLZF deficient patient. PLoS One 6(9): e24441. Available at: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167854/.
-
(2011)
PLoS One
, vol.6
, Issue.9
, pp. e24441
-
-
Eidson, M.1
Wahlstrom, J.2
Beaulieu, A.M.3
Zaidi, B.4
Carsons, S.E.5
Crow, P.K.6
Yuan, J.7
Wolchok, J.D.8
Horsthemke, B.9
Wieczorek, D.10
Sant'Angelo, D.B.11
-
34
-
-
33847334699
-
Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome
-
Heintzman, N. D., R. K. Stuart, G. Hon, Y. Fu, C. W. Ching, R. D. Hawkins, L. O. Barrera, S. Van Calcar, C. Qu, K. A. Ching, et al. 2007. Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome. Nat. Genet. 39: 311-318.
-
(2007)
Nat. Genet.
, vol.39
, pp. 311-318
-
-
Heintzman, N.D.1
Stuart, R.K.2
Hon, G.3
Fu, Y.4
Ching, C.W.5
Hawkins, R.D.6
Barrera, L.O.7
Van Calcar, S.8
Qu, C.9
Ching, K.A.10
-
35
-
-
78650758676
-
Histone H3K27ac separates active from poised enhancers and predicts developmental state
-
Creyghton, M. P., A. W. Cheng, G. G. Welstead, T. Kooistra, B. W. Carey, E. J. Steine, J. Hanna, M. A. Lodato, G. M. Frampton, P. A. Sharp, et al. 2010. Histone H3K27ac separates active from poised enhancers and predicts developmental state. Proc. Natl. Acad. Sci. USA 107: 21931-21936.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 21931-21936
-
-
Creyghton, M.P.1
Cheng, A.W.2
Welstead, G.G.3
Kooistra, T.4
Carey, B.W.5
Steine, E.J.6
Hanna, J.7
Lodato, M.A.8
Frampton, G.M.9
Sharp, P.A.10
-
36
-
-
60149091656
-
ChIP-seq accurately predicts tissue-specific activity of enhancers
-
Visel, A., M. J. Blow, Z. Li, T. Zhang, J. A. Akiyama, A. Holt, I. Plajzer-Frick, M. Shoukry, C. Wright, F. Chen, et al. 2009. ChIP-seq accurately predicts tissue-specific activity of enhancers. Nature 457: 854-858.
-
(2009)
Nature
, vol.457
, pp. 854-858
-
-
Visel, A.1
Blow, M.J.2
Li, Z.3
Zhang, T.4
Akiyama, J.A.5
Holt, A.6
Plajzer-Frick, I.7
Shoukry, M.8
Wright, C.9
Chen, F.10
-
37
-
-
84885129176
-
IL-21-producing Th cells in immunity and autoimmunity
-
Liu, S. M., and C. King. 2013. IL-21-producing Th cells in immunity and autoimmunity. J. Immunol. 191: 3501-3506.
-
(2013)
J. Immunol.
, vol.191
, pp. 3501-3506
-
-
Liu, S.M.1
King, C.2
-
38
-
-
84869866718
-
BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs
-
Mathew, R., M. P. Seiler, S. T. Scanlon, A. P. Mao, M. G. Constantinides, C. Bertozzi-Villa, J. D. Singer, and A. Bendelac. 2012. BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs. Nature 491: 618-621.
-
(2012)
Nature
, vol.491
, pp. 618-621
-
-
Mathew, R.1
Seiler, M.P.2
Scanlon, S.T.3
Mao, A.P.4
Constantinides, M.G.5
Bertozzi-Villa, C.6
Singer, J.D.7
Bendelac, A.8
-
39
-
-
2642522727
-
Plzf is required in adult male germ cells for stem cell self-renewal
-
Buaas, F. W., A. L. Kirsh, M. Sharma, D. J. McLean, J. L. Morris, M. D. Griswold, D. G. de Rooij, and R. E. Braun. 2004. Plzf is required in adult male germ cells for stem cell self-renewal. Nat. Genet. 36: 647-652.
-
(2004)
Nat. Genet.
, vol.36
, pp. 647-652
-
-
Buaas, F.W.1
Kirsh, A.L.2
Sharma, M.3
McLean, D.J.4
Morris, J.L.5
Griswold, M.D.6
De Rooij, D.G.7
Braun, R.E.8
-
40
-
-
49249135394
-
Human interleukin 17-producing cells originate from a CD161+CD4+ T cell precursor
-
Cosmi, L., R. De Palma, V. Santarlasci, L. Maggi, M. Capone, F. Frosali, G. Rodolico, V. Querci, G. Abbate, R. Angeli, et al. 2008. Human interleukin 17-producing cells originate from a CD161+CD4+ T cell precursor. J. Exp. Med. 205: 1903-1916.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 1903-1916
-
-
Cosmi, L.1
De Palma, R.2
Santarlasci, V.3
Maggi, L.4
Capone, M.5
Frosali, F.6
Rodolico, G.7
Querci, V.8
Abbate, G.9
Angeli, R.10
-
41
-
-
80052260527
-
A genome-wide association study identifies two new risk loci for Graves' disease
-
Chu, X., C. M. Pan, S. X. Zhao, J. Liang, G. Q. Gao, X. M. Zhang, G. Y. Yuan, C. G. Li, L. Q. Xue, M. Shen, et al China Consortium for Genetics of Autoimmune Thyroid Disease. 2011. A genome-wide association study identifies two new risk loci for Graves' disease. Nat. Genet. 43: 897-901.
-
(2011)
Nat. Genet.
, vol.43
, pp. 897-901
-
-
Chu, X.1
Pan, C.M.2
Zhao, S.X.3
Liang, J.4
Gao, G.Q.5
Zhang, X.M.6
Yuan, G.Y.7
Li, C.G.8
Xue, L.Q.9
Shen, M.10
-
42
-
-
77952885768
-
A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility
-
Kochi, Y., Y. Okada, A. Suzuki, K. Ikari, C. Terao, A. Takahashi, K. Yamazaki, N. Hosono, K. Myouzen, T. Tsunoda, et al. 2010. A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility. Nat. Genet. 42: 515-519.
-
(2010)
Nat. Genet.
, vol.42
, pp. 515-519
-
-
Kochi, Y.1
Okada, Y.2
Suzuki, A.3
Ikari, K.4
Terao, C.5
Takahashi, A.6
Yamazaki, K.7
Hosono, N.8
Myouzen, K.9
Tsunoda, T.10
-
43
-
-
77954143766
-
Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC
-
Quan, C., Y. Q. Ren, L. H. Xiang, L. D. Sun, A. E. Xu, X. H. Gao, H. D. Chen, X. M. Pu, R. N. Wu, C. Z. Liang, et al. 2010. Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC. Nat. Genet. 42: 614-618.
-
(2010)
Nat. Genet.
, vol.42
, pp. 614-618
-
-
Quan, C.1
Ren, Y.Q.2
Xiang, L.H.3
Sun, L.D.4
Xu, A.E.5
Gao, X.H.6
Chen, H.D.7
Pu, X.M.8
Wu, R.N.9
Liang, C.Z.10
-
44
-
-
77952888454
-
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci
-
Stahl, E. A., S. Raychaudhuri, E. F. Remmers, G. Xie, S. Eyre, B. P. Thomson, Y. Li, F. A. Kurreeman, A. Zhernakova, A. Hinks, et al BIRAC Consortium; YEAR Consortium. 2010. Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. Nat. Genet. 42: 508-514.
-
(2010)
Nat. Genet.
, vol.42
, pp. 508-514
-
-
Stahl, E.A.1
Raychaudhuri, S.2
Remmers, E.F.3
Xie, G.4
Eyre, S.5
Thomson, B.P.6
Li, Y.7
Kurreeman, F.A.8
Zhernakova, A.9
Hinks, A.10
-
45
-
-
61549115034
-
Diverse genomewide association studies associate the IL12/IL23 pathway with Crohn Disease
-
Wang, K., H. Zhang, S. Kugathasan, V. Annese, J. P. Bradfield, R. K. Russell, P. M. Sleiman, M. Imielinski, J. Glessner, C. Hou, et al. 2009. Diverse genomewide association studies associate the IL12/IL23 pathway with Crohn Disease. Am. J. Hum. Genet. 84: 399-405.
-
(2009)
Am. J. Hum. Genet.
, vol.84
, pp. 399-405
-
-
Wang, K.1
Zhang, H.2
Kugathasan, S.3
Annese, V.4
Bradfield, J.P.5
Russell, R.K.6
Sleiman, P.M.7
Imielinski, M.8
Glessner, J.9
Hou, C.10
-
46
-
-
67651171182
-
Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells
-
Trifari, S., C. D. Kaplan, E. H. Tran, N. K. Crellin, and H. Spits. 2009. Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells. Nat. Immunol. 10: 864-871.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 864-871
-
-
Trifari, S.1
Kaplan, C.D.2
Tran, E.H.3
Crellin, N.K.4
Spits, H.5
-
47
-
-
0034123470
-
Plzf regulates limb and axial skeletal patterning
-
Barna, M., N. Hawe, L. Niswander, and P. P. Pandolfi. 2000. Plzf regulates limb and axial skeletal patterning. Nat. Genet. 25: 166-172.
-
(2000)
Nat. Genet.
, vol.25
, pp. 166-172
-
-
Barna, M.1
Hawe, N.2
Niswander, L.3
Pandolfi, P.P.4
-
48
-
-
79956194247
-
Promyelocytic leukemia zinc finger turns on the effector T cell program without requirement for agonist TCR signaling
-
Savage, A. K., M. G. Constantinides, and A. Bendelac. 2011. Promyelocytic leukemia zinc finger turns on the effector T cell program without requirement for agonist TCR signaling. J. Immunol. 186: 5801-5806.
-
(2011)
J. Immunol.
, vol.186
, pp. 5801-5806
-
-
Savage, A.K.1
Constantinides, M.G.2
Bendelac, A.3
-
49
-
-
76149123542
-
Generation of PLZF+ CD4+ T cells via MHC class II-dependent thymocyte-thymocyte interaction is a physiological process in humans
-
Lee, Y. J., Y. K. Jeon, B. H. Kang, D. H. Chung, C. G. Park, H. Y. Shin, K. C. Jung, and S. H. Park. 2010. Generation of PLZF+ CD4+ T cells via MHC class II-dependent thymocyte-thymocyte interaction is a physiological process in humans. J. Exp. Med. 207: 237-246.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 237-246
-
-
Lee, Y.J.1
Jeon, Y.K.2
Kang, B.H.3
Chung, D.H.4
Park, C.G.5
Shin, H.Y.6
Jung, K.C.7
Park, S.H.8
-
50
-
-
34249026300
-
High-resolution profiling of histone methylations in the human genome
-
Barski, A., S. Cuddapah, K. Cui, T.-Y. Roh, D. E. Schones, Z. Wang, G. Wei, I. Chepelev, and K. Zhao. 2007. High-resolution profiling of histone methylations in the human genome. Cell 129: 823-837.
-
(2007)
Cell
, vol.129
, pp. 823-837
-
-
Barski, A.1
Cuddapah, S.2
Cui, K.3
Roh, T.-Y.4
Schones, D.E.5
Wang, Z.6
Wei, G.7
Chepelev, I.8
Zhao, K.9
-
51
-
-
65549104157
-
Histone modifications at human enhancers reflect global cell-type-specific gene expression
-
Heintzman, N. D., G. C. Hon, R. D. Hawkins, P. Kheradpour, A. Stark, L. F. Harp, Z. Ye, L. K. Lee, R. K. Stuart, C. W. Ching, et al. 2009. Histone modifications at human enhancers reflect global cell-type-specific gene expression. Nature 459: 108-112.
-
(2009)
Nature
, vol.459
, pp. 108-112
-
-
Heintzman, N.D.1
Hon, G.C.2
Hawkins, R.D.3
Kheradpour, P.4
Stark, A.5
Harp, L.F.6
Ye, Z.7
Lee, L.K.8
Stuart, R.K.9
Ching, C.W.10
-
52
-
-
80054910846
-
H3K4 trimethylation provides an epigenetic signature of active enhancers
-
Pekowska, A., T. Benoukraf, J. Zacarias-Cabeza, M. Belhocine, F. Koch, H. Holota, J. Imbert, J. C. Andrau, P. Ferrier, and S. Spicuglia. 2011. H3K4 trimethylation provides an epigenetic signature of active enhancers. EMBO J. 30: 4198-4210.
-
(2011)
EMBO J.
, vol.30
, pp. 4198-4210
-
-
Pekowska, A.1
Benoukraf, T.2
Zacarias-Cabeza, J.3
Belhocine, M.4
Koch, F.5
Holota, H.6
Imbert, J.7
Andrau, J.C.8
Ferrier, P.9
Spicuglia, S.10
-
53
-
-
84855180224
-
Initiating RNA polymerase II and TIPs as hallmarks of enhancer activity and tissue-specificity
-
Koch, F., and J. C. Andrau. 2011. Initiating RNA polymerase II and TIPs as hallmarks of enhancer activity and tissue-specificity. Transcription 2: 263-268.
-
(2011)
Transcription
, vol.2
, pp. 263-268
-
-
Koch, F.1
Andrau, J.C.2
-
54
-
-
9944238799
-
HDAC4 mediates transcriptional repression by the acute promyelocytic leukaemia-associated protein PLZF
-
Chauchereau, A., M. Mathieu, J. de Saintignon, R. Ferreira, L. L. Pritchard, Z. Mishal, A. Dejean, and A. Harel-Bellan. 2004. HDAC4 mediates transcriptional repression by the acute promyelocytic leukaemia-associated protein PLZF. Oncogene 23: 8777-8784.
-
(2004)
Oncogene
, vol.23
, pp. 8777-8784
-
-
Chauchereau, A.1
Mathieu, M.2
De Saintignon, J.3
Ferreira, R.4
Pritchard, L.L.5
Mishal, Z.6
Dejean, A.7
Harel-Bellan, A.8
-
55
-
-
0032516221
-
Histone deacetylase associated with mSin3A mediates repression by the acute promyelocytic leukemia-associated PLZF protein
-
David, G., L. Alland, S. H. Hong, C. W. Wong, R. A. DePinho, and A. Dejean. 1998. Histone deacetylase associated with mSin3A mediates repression by the acute promyelocytic leukemia-associated PLZF protein. Oncogene 16: 2549-2556.
-
(1998)
Oncogene
, vol.16
, pp. 2549-2556
-
-
David, G.1
Alland, L.2
Hong, S.H.3
Wong, C.W.4
DePinho, R.A.5
Dejean, A.6
-
56
-
-
20744456118
-
Histone acetyltransferase activity of p300 is required for transcriptional repression by the promyelocytic leukemia zinc finger protein
-
Guidez, F., L. Howell, M. Isalan, M. Cebrat, R. M. Alani, S. Ivins, I. Hormaeche, M. J. McConnell, S. Pierce, P. A. Cole, et al. 2005. Histone acetyltransferase activity of p300 is required for transcriptional repression by the promyelocytic leukemia zinc finger protein. Mol. Cell. Biol. 25: 5552-5566.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 5552-5566
-
-
Guidez, F.1
Howell, L.2
Isalan, M.3
Cebrat, M.4
Alani, R.M.5
Ivins, S.6
Hormaeche, I.7
McConnell, M.J.8
Pierce, S.9
Cole, P.A.10
-
57
-
-
0030847164
-
SMRT corepressor interacts with PLZF and with the PML-retinoic acid receptor alpha (RARalpha) and PLZF-RARalpha oncoproteins associated with acute promyelocytic leukemia
-
Hong, S. H., G. David, C. W. Wong, A. Dejean, and M. L. Privalsky. 1997. SMRT corepressor interacts with PLZF and with the PML-retinoic acid receptor alpha (RARalpha) and PLZF-RARalpha oncoproteins associated with acute promyelocytic leukemia. Proc. Natl. Acad. Sci. USA 94: 9028-9033.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 9028-9033
-
-
Hong, S.H.1
David, G.2
Wong, C.W.3
Dejean, A.4
Privalsky, M.L.5
-
59
-
-
10744230356
-
A novel angiotensin II type 2 receptor signaling pathway: Possible role in cardiac hypertrophy
-
Senbonmatsu, T., T. Saito, E. J. Landon, O. Watanabe, E. Price, Jr., R. L. Roberts, H. Imboden, T. G. Fitzgerald, F. A. Gaffney, and T. Inagami. 2003. A novel angiotensin II type 2 receptor signaling pathway: possible role in cardiac hypertrophy. EMBO J. 22: 6471-6482.
-
(2003)
EMBO J.
, vol.22
, pp. 6471-6482
-
-
Senbonmatsu, T.1
Saito, T.2
Landon, E.J.3
Watanabe, O.4
Price, E.5
Roberts, R.L.6
Imboden, H.7
Fitzgerald, T.G.8
Gaffney, F.A.9
Inagami, T.10
-
60
-
-
66949167924
-
Promyelocytic leukemia zinc finger protein regulates interferon-mediated innate immunity
-
Xu, D., M. Holko, A. J. Sadler, B. Scott, S. Higashiyama, W. Berkofsky-Fessler, M. J. McConnell, P. P. Pandolfi, J. D. Licht, and B. R. Williams. 2009. Promyelocytic leukemia zinc finger protein regulates interferon-mediated innate immunity. Immunity 30: 802-816.
-
(2009)
Immunity
, vol.30
, pp. 802-816
-
-
Xu, D.1
Holko, M.2
Sadler, A.J.3
Scott, B.4
Higashiyama, S.5
Berkofsky-Fessler, W.6
McConnell, M.J.7
Pandolfi, P.P.8
Licht, J.D.9
Williams, B.R.10
-
61
-
-
84867581744
-
A validated regulatory network for Th17 cell specification
-
Ciofani, M., A. Madar, C. Galan, M. Sellars, K. Mace, F. Pauli, A. Agarwal, W. Huang, C. N. Parkurst, M. Muratet, et al. 2012. A validated regulatory network for Th17 cell specification. Cell 151: 289-303.
-
(2012)
Cell
, vol.151
, pp. 289-303
-
-
Ciofani, M.1
Madar, A.2
Galan, C.3
Sellars, M.4
Mace, K.5
Pauli, F.6
Agarwal, A.7
Huang, W.8
Parkurst, C.N.9
Muratet, M.10
-
62
-
-
77958611660
-
Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors
-
Zhu, J., and W. E. Paul. 2010. Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors. Immunol. Rev. 238: 247-262.
-
(2010)
Immunol. Rev.
, vol.238
, pp. 247-262
-
-
Zhu, J.1
Paul, W.E.2
-
63
-
-
54549100120
-
Interactions among the transcription factors Runx1, RORgammat and Foxp3 regulate the differentiation of interleukin 17-producing T cells
-
Zhang, F., G. Meng, and W. Strober. 2008. Interactions among the transcription factors Runx1, RORgammat and Foxp3 regulate the differentiation of interleukin 17-producing T cells. Nat. Immunol. 9: 1297-1306.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 1297-1306
-
-
Zhang, F.1
Meng, G.2
Strober, W.3
-
64
-
-
79955538365
-
Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity
-
Huh, J. R., M. W. Leung, P. Huang, D. A. Ryan, M. R. Krout, R. R. Malapaka, J. Chow, N. Manel, M. Ciofani, S. V. Kim, et al. 2011. Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity. Nature 472: 486-490.
-
(2011)
Nature
, vol.472
, pp. 486-490
-
-
Huh, J.R.1
Leung, M.W.2
Huang, P.3
Ryan, D.A.4
Krout, M.R.5
Malapaka, R.R.6
Chow, J.7
Manel, N.8
Ciofani, M.9
Kim, S.V.10
-
65
-
-
84862959581
-
Human MAIT and CD8αα cells develop from a pool of type-17 precommitted CD8+ T cells
-
Walker, L. J., Y. H. Kang, M. O. Smith, H. Tharmalingham, N. Ramamurthy, V. M. Fleming, N. Sahgal, A. Leslie, Y. Oo, A. Geremia, et al. 2012. Human MAIT and CD8αα cells develop from a pool of type-17 precommitted CD8+ T cells. Blood 119: 422-433.
-
(2012)
Blood
, vol.119
, pp. 422-433
-
-
Walker, L.J.1
Kang, Y.H.2
Smith, M.O.3
Tharmalingham, H.4
Ramamurthy, N.5
Fleming, V.M.6
Sahgal, N.7
Leslie, A.8
Oo, Y.9
Geremia, A.10
-
66
-
-
84902147310
-
TLR-induced cytokines promote effective proinflammatory natural Th17 cell responses
-
Massot, B., M. L. Michel, S. Diem, C. Ohnmacht, S. Latour, M. Dy, G. Eberl, and M. C. Leite-de-Moraes. 2014. TLR-induced cytokines promote effective proinflammatory natural Th17 cell responses. J. Immunol. 192: 5635-5642.
-
(2014)
J. Immunol.
, vol.192
, pp. 5635-5642
-
-
Massot, B.1
Michel, M.L.2
Diem, S.3
Ohnmacht, C.4
Latour, S.5
Dy, M.6
Eberl, G.7
Leite-De-Moraes, M.C.8
|