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Volumn 42, Issue 7, 2010, Pages 614-618

Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC

(66)  Quan, Cheng a   Ren, Yun Qing a   Xiang, Lei Hong b   Sun, Liang Dan a   Xu, Ai E a,c   Gao, Xing Hua d   Chen, Hong Duo d   Pu, Xiong Ming a,e   Wu, Ri Na f   Liang, Chao Zhao a   Li, Jia Bin a   Gao, Tian Wen g   Zhang, Jian Zhong h   Wang, Xiu Li a,i   Wang, Jun j   Yang, Rong Ya a,k   Liang, Ling l   Yu, Jian Bin m   Zuo, Xian Bo a   Zhang, Sheng Quan a   more..


Author keywords

[No Author keywords available]

Indexed keywords

HLA A ANTIGEN; HLA B ANTIGEN; HLA C ANTIGEN;

EID: 77954143766     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.603     Document Type: Article
Times cited : (156)

References (47)
  • 3
    • 41149116756 scopus 로고    scopus 로고
    • A Romanian population isolate with high frequency of vitiligo and associated autoimmune diseases
    • Birlea, S.A., Fain, P.R. & Spritz, R.A. A Romanian population isolate with high frequency of vitiligo and associated autoimmune diseases. Arch. Dermatol. 144, 310-316 (2008).
    • (2008) Arch. Dermatol. , vol.144 , pp. 310-316
    • Birlea, S.A.1    Fain, P.R.2    Spritz, R.A.3
  • 5
    • 0018590938 scopus 로고
    • Psychological reaction to chronic skin disorders: A study of patients with vitiligo
    • Porter, J., Beuf, A.H., Nordlund, J.J. & Lerner, A.B. Psychological reaction to chronic skin disorders: a study of patients with vitiligo. Gen. Hosp. Psychiatry 1, 73-77 (1979).
    • (1979) Gen. Hosp. Psychiatry , vol.1 , pp. 73-77
    • Porter, J.1    Beuf, A.H.2    Nordlund, J.J.3    Lerner, A.B.4
  • 6
    • 0037986326 scopus 로고    scopus 로고
    • Epidemiology of vitiligo and associated autoimmune diseases in Caucasian probands and their families
    • Alkhateeb, A., Fain, P.R., Thody, A., Bennett, D.C. & Spritz, R.A. Epidemiology of vitiligo and associated autoimmune diseases in Caucasian probands and their families. Pigment Cell Res. 16, 208-214 (2003).
    • (2003) Pigment Cell Res. , vol.16 , pp. 208-214
    • Alkhateeb, A.1    Fain, P.R.2    Thody, A.3    Bennett, D.C.4    Spritz, R.A.5
  • 7
    • 33748307412 scopus 로고    scopus 로고
    • A review and a new hypothesis for non-immunological pathogenetic mechanisms in vitiligo
    • Dell'anna, M.L. & Picardo, M. A review and a new hypothesis for non-immunological pathogenetic mechanisms in vitiligo. Pigment Cell Res. 19, 406-411 (2006).
    • (2006) Pigment Cell Res. , vol.19 , pp. 406-411
    • Dell'Anna, M.L.1    Picardo, M.2
  • 8
    • 42249102012 scopus 로고    scopus 로고
    • The genetics of generalized vitiligo
    • Spritz, R.A. The genetics of generalized vitiligo. Curr. Dir. Autoimmun. 10, 244-257 (2008).
    • (2008) Curr. Dir. Autoimmun. , vol.10 , pp. 244-257
    • Spritz, R.A.1
  • 9
    • 4444331806 scopus 로고    scopus 로고
    • Characteristics of genetic epidemiology and genetic models for vitiligo
    • Zhang, X.J. et al. Characteristics of genetic epidemiology and genetic models for vitiligo. J. Am. Acad. Dermatol. 51, 383-390 (2004).
    • (2004) J. Am. Acad. Dermatol. , vol.51 , pp. 383-390
    • Zhang, X.J.1
  • 10
    • 0035208598 scopus 로고    scopus 로고
    • Evidence for a susceptibility gene, SLEV1, on chromosome 17p13 in families with vitiligo-related systemic lupus erythematosus
    • Nath, S.K. et al. Evidence for a susceptibility gene, SLEV1, on chromosome 17p13 in families with vitiligo-related systemic lupus erythematosus. Am. J. Hum. Genet. 69, 1401-1406 (2001).
    • (2001) Am. J. Hum. Genet. , vol.69 , pp. 1401-1406
    • Nath, S.K.1
  • 11
    • 18344388283 scopus 로고    scopus 로고
    • Mapping of an autoimmunity susceptibility locus (AIS1) to chromosome 1p31.3-p32.2
    • Alkhateeb, A. et al. Mapping of an autoimmunity susceptibility locus (AIS1) to chromosome 1p31.3-p32.2. Hum. Mol. Genet. 11, 661-667 (2002).
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 661-667
    • Alkhateeb, A.1
  • 12
    • 0345742508 scopus 로고    scopus 로고
    • Novel vitiligo susceptibility loci on chromosomes 7 (AIS2) and 8 (AIS3), confrmation of SLEV1 on chromosome 17, and their roles in an autoimmune diathesis
    • Spritz, R.A., Gowan, K., Bennett, D.C. & Fain, P.R. Novel vitiligo susceptibility loci on chromosomes 7 (AIS2) and 8 (AIS3), confrmation of SLEV1 on chromosome 17, and their roles in an autoimmune diathesis. Am. J. Hum. Genet. 74, 188-191 (2004).
    • (2004) Am. J. Hum. Genet. , vol.74 , pp. 188-191
    • Spritz, R.A.1    Gowan, K.2    Bennett, D.C.3    Fain, P.R.4
  • 13
    • 21044445919 scopus 로고    scopus 로고
    • A novel linkage to generalized vitiligo on 4q13-q21 identifed in a genomewide linkage analysis of Chinese families
    • Chen, J.J. et al. A novel linkage to generalized vitiligo on 4q13-q21 identifed in a genomewide linkage analysis of Chinese families. Am. J. Hum. Genet. 76, 1057-1065 (2005).
    • (2005) Am. J. Hum. Genet. , vol.76 , pp. 1057-1065
    • Chen, J.J.1
  • 14
    • 33947497237 scopus 로고    scopus 로고
    • NALP1 in vitiligo-associated multiple autoimmune disease
    • Jin, Y. et al. NALP1 in vitiligo-associated multiple autoimmune disease. N. Engl. J. Med. 356, 1216-1225 (2007).
    • (2007) N. Engl. J. Med. , vol.356 , pp. 1216-1225
    • Jin, Y.1
  • 15
    • 67651233779 scopus 로고    scopus 로고
    • Genetic variation of promoter sequence modulates XBP1 expression and genetic risk for vitiligo
    • Ren, Y. et al. Genetic variation of promoter sequence modulates XBP1 expression and genetic risk for vitiligo. PLoS Genet. 5, e1000523 (2009).
    • (2009) PLoS Genet. , vol.5
    • Ren, Y.1
  • 16
    • 34447304633 scopus 로고    scopus 로고
    • Genetic variations in NALP1 are associated with generalized vitiligo in a Romanian population
    • Jin, Y., Birlea, S.A., Fain, P.R. & Spritz, R.A. Genetic variations in NALP1 are associated with generalized vitiligo in a Romanian population. J. Invest. Dermatol. 127, 2558-2562 (2007).
    • (2007) J. Invest. Dermatol. , vol.127 , pp. 2558-2562
    • Jin, Y.1    Birlea, S.A.2    Fain, P.R.3    Spritz, R.A.4
  • 17
    • 0034819257 scopus 로고    scopus 로고
    • Linkage and association of HLA class II genes with vitiligo in a Dutch population
    • Zamani, M. et al. Linkage and association of HLA class II genes with vitiligo in a Dutch population. Br. J. Dermatol. 145, 90-94 (2001).
    • (2001) Br. J. Dermatol. , vol.145 , pp. 90-94
    • Zamani, M.1
  • 18
    • 0036556302 scopus 로고    scopus 로고
    • Vitiligo: Complex segregation and linkage disequilibrium analyses with respect to microsatellite loci spanning the HLA
    • Arcos-Burgos, M. et al. Vitiligo: complex segregation and linkage disequilibrium analyses with respect to microsatellite loci spanning the HLA. Hum. Genet. 110, 334-342 (2002).
    • (2002) Hum. Genet. , vol.110 , pp. 334-342
    • Arcos-Burgos, M.1
  • 19
    • 77951780943 scopus 로고    scopus 로고
    • Variant of TYR and autoimmunity susceptibility loci in generalized vitiligo
    • Jin, Y. et al. Variant of TYR and autoimmunity susceptibility loci in generalized vitiligo. N. Engl. J. Med. 362, 1686-1697 (2010).
    • (2010) N. Engl. J. Med. , vol.362 , pp. 1686-1697
    • Jin, Y.1
  • 20
    • 33846394421 scopus 로고    scopus 로고
    • Association of vitiligo with HLA-A2: A meta-analysis
    • Liu, J.B. et al. Association of vitiligo with HLA-A2: a meta-analysis. J. Eur. Acad. Dermatol. Venereol. 21, 205-213 (2007).
    • (2007) J. Eur. Acad. Dermatol. Venereol. , vol.21 , pp. 205-213
    • Liu, J.B.1
  • 21
    • 3242755027 scopus 로고    scopus 로고
    • Association of HLA class i alleles with vitiligo in Chinese Hans
    • Zhang, X.J. et al. Association of HLA class I alleles with vitiligo in Chinese Hans. J. Dermatol. Sci. 35, 165-168 (2004).
    • (2004) J. Dermatol. Sci. , vol.35 , pp. 165-168
    • Zhang, X.J.1
  • 22
    • 17144471599 scopus 로고    scopus 로고
    • Association of HLA class i antigens and HLA class II alleles with vitiligo in a Turkish population
    • Taştan, H.B., Akar, A., Orkunoglu, F.E., Arca, E. & Inal, A. Association of HLA class I antigens and HLA class II alleles with vitiligo in a Turkish population. Pigment Cell Res. 17, 181-184 (2004).
    • (2004) Pigment Cell Res. , vol.17 , pp. 181-184
    • Taştan, H.B.1    Akar, A.2    Orkunoglu, F.E.3    Arca, E.4    Inal, A.5
  • 23
    • 70350629871 scopus 로고    scopus 로고
    • Genome-wide association study in a Chinese Han population identifes nine new susceptibility loci for systemic lupus erythematosus
    • Han, J.W. et al. Genome-wide association study in a Chinese Han population identifes nine new susceptibility loci for systemic lupus erythematosus. Nat. Genet. 41, 1234-1237 (2009).
    • (2009) Nat. Genet. , vol.41 , pp. 1234-1237
    • Han, J.W.1
  • 24
    • 59149096149 scopus 로고    scopus 로고
    • Psoriasis genome-wide association study identifes susceptibility variants within LCE gene cluster at 1q21
    • Zhang, X.J. et al. Psoriasis genome-wide association study identifes susceptibility variants within LCE gene cluster at 1q21. Nat. Genet. 41, 205-210 (2009).
    • (2009) Nat. Genet. , vol.41 , pp. 205-210
    • Zhang, X.J.1
  • 25
    • 74049127960 scopus 로고    scopus 로고
    • Genomewide association study of leprosy
    • Zhang, F.R. et al. Genomewide association study of leprosy. N. Engl. J. Med. 361, 2609-2618 (2009).
    • (2009) N. Engl. J. Med. , vol.361 , pp. 2609-2618
    • Zhang, F.R.1
  • 26
    • 33646132515 scopus 로고    scopus 로고
    • Characterization of RNASET2, the frst human member of the Rh/T2/S family of glycoproteins
    • Campomenosi, P. et al. Characterization of RNASET2, the frst human member of the Rh/T2/S family of glycoproteins. Arch. Biochem. Biophys. 449, 17-26 (2006).
    • (2006) Arch. Biochem. Biophys. , vol.449 , pp. 17-26
    • Campomenosi, P.1
  • 27
    • 17744374767 scopus 로고    scopus 로고
    • Cloning and characterization of a senescence inducing and class II tumor suppressor gene in ovarian carcinoma at chromosome region 6q27
    • Acquati, F. et al. Cloning and characterization of a senescence inducing and class II tumor suppressor gene in ovarian carcinoma at chromosome region 6q27. Oncogene 20, 980-988 (2001).
    • (2001) Oncogene , vol.20 , pp. 980-988
    • Acquati, F.1
  • 28
    • 44849118328 scopus 로고    scopus 로고
    • RNASET2 as a tumor antagonizing gene in a melanoma cancer model
    • Monti, L. et al. RNASET2 as a tumor antagonizing gene in a melanoma cancer model. Oncol. Res. 17, 69-74 (2008).
    • (2008) Oncol. Res. , vol.17 , pp. 69-74
    • Monti, L.1
  • 29
    • 65249152479 scopus 로고    scopus 로고
    • The RNase Rny1p cleaves tRNAs and promotes cell death during oxidative stress in Saccharomyces cerevisiae
    • Thompson, D.M. & Parker, R. The RNase Rny1p cleaves tRNAs and promotes cell death during oxidative stress in Saccharomyces cerevisiae. J. Cell Biol. 185, 43-50 (2009).
    • (2009) J. Cell Biol. , vol.185 , pp. 43-50
    • Thompson, D.M.1    Parker, R.2
  • 30
    • 0032884755 scopus 로고    scopus 로고
    • 2) accumulation in the epidermis of patients with vitiligo and its successful removal by a UVB-activated pseudocatalase
    • 2) accumulation in the epidermis of patients with vitiligo and its successful removal by a UVB-activated pseudocatalase. J. Investig. Dermatol. Symp. Proc. 4, 91-96 (1999).
    • (1999) J. Investig. Dermatol. Symp. Proc. , vol.4 , pp. 91-96
    • Schallreuter, K.U.1
  • 31
    • 33744796303 scopus 로고    scopus 로고
    • Structure of the N-terminal domain of the FOP (FGFR1OP) protein and implications for its dimerization and centrosomal localization
    • Mikolajka, A. et al. Structure of the N-terminal domain of the FOP (FGFR1OP) protein and implications for its dimerization and centrosomal localization. J. Mol. Biol. 359, 863-875 (2006).
    • (2006) J. Mol. Biol. , vol.359 , pp. 863-875
    • Mikolajka, A.1
  • 32
    • 0033558253 scopus 로고    scopus 로고
    • The t(6;8)(q27;p11) translocation in a stem cell myeloproliferative disorder fuses a novel gene, FOP, to fbroblast growth factor receptor 1
    • Popovici, C. et al. The t(6;8)(q27;p11) translocation in a stem cell myeloproliferative disorder fuses a novel gene, FOP, to fbroblast growth factor receptor 1. Blood 93, 1381-1389 (1999).
    • (1999) Blood , vol.93 , pp. 1381-1389
    • Popovici, C.1
  • 33
    • 65949101469 scopus 로고    scopus 로고
    • The centrosomal FOP protein is required for cell cycle progression and survival
    • Acquaviva, C. et al. The centrosomal FOP protein is required for cell cycle progression and survival. Cell Cycle 8, 1217-1227 (2009).
    • (2009) Cell Cycle , vol.8 , pp. 1217-1227
    • Acquaviva, C.1
  • 35
    • 32244441218 scopus 로고    scopus 로고
    • + T cell crosspriming in vivo
    • + T cell crosspriming in vivo. Immunity 24, 191-201 (2006).
    • (2006) Immunity , vol.24 , pp. 191-201
    • Le Borgne, M.1
  • 36
    • 76649118097 scopus 로고    scopus 로고
    • Genome-wide association study of generalized vitiligo in an isolated European founder population identifes SMOC2, in close proximity to IDDM8
    • Birlea, S.A., Gowan, K., Fain, P.R. & Spritz, R.A. Genome-wide association study of generalized vitiligo in an isolated European founder population identifes SMOC2, in close proximity to IDDM8. J. Invest. Dermatol. 130, 798-803 (2010).
    • (2010) J. Invest. Dermatol. , vol.130 , pp. 798-803
    • Birlea, S.A.1    Gowan, K.2    Fain, P.R.3    Spritz, R.A.4
  • 37
    • 48349136889 scopus 로고    scopus 로고
    • Genome-wide association defnes more than 30 distinct susceptibility loci for Crohn's disease
    • Barrett, J.C. et al. Genome-wide association defnes more than 30 distinct susceptibility loci for Crohn's disease. Nat. Genet. 40, 955-962 (2008).
    • (2008) Nat. Genet. , vol.40 , pp. 955-962
    • Barrett, J.C.1
  • 38
    • 33645500772 scopus 로고    scopus 로고
    • Identifying a common molecular mechanism for inhibition of MITF and STAT3 by PIAS3
    • Levy, C. et al. Identifying a common molecular mechanism for inhibition of MITF and STAT3 by PIAS3. Blood 107, 2839-2845 (2006).
    • (2006) Blood , vol.107 , pp. 2839-2845
    • Levy, C.1
  • 39
    • 21844478747 scopus 로고    scopus 로고
    • Integrative genomic analyses identify MITF as a lineage survival oncogene amplifed in malignant melanoma
    • Garraway, L.A. et al. Integrative genomic analyses identify MITF as a lineage survival oncogene amplifed in malignant melanoma. Nature 436, 117-122 (2005).
    • (2005) Nature , vol.436 , pp. 117-122
    • Garraway, L.A.1
  • 40
    • 70649113728 scopus 로고    scopus 로고
    • Common variants at fve new loci associated with early-onset infammatory bowel disease
    • Imielinski, M. et al. Common variants at fve new loci associated with early-onset infammatory bowel disease. Nat. Genet. 41, 1335-1340 (2009).
    • (2009) Nat. Genet. , vol.41 , pp. 1335-1340
    • Imielinski, M.1
  • 41
    • 59449092325 scopus 로고    scopus 로고
    • The analysis of genetics and associated autoimmune diseases in Chinese vitiligo patients
    • Zhang, Z. et al. The analysis of genetics and associated autoimmune diseases in Chinese vitiligo patients. Arch. Dermatol. Res. 301, 167-173 (2009).
    • (2009) Arch. Dermatol. Res. , vol.301 , pp. 167-173
    • Zhang, Z.1
  • 42
    • 33846175345 scopus 로고    scopus 로고
    • The defnition and assessment of vitiligo: A consensus report of the Vitiligo European Task Force
    • Taïeb, A. & Picardo, M. The defnition and assessment of vitiligo: a consensus report of the Vitiligo European Task Force. Pigment Cell Res. 20, 27-35 (2007).
    • (2007) Pigment Cell Res. , vol.20 , pp. 27-35
    • Taïeb, A.1    Picardo, M.2
  • 43
    • 34548292504 scopus 로고    scopus 로고
    • PLINK: A tool set for whole-genome association and population-based linkage analyses
    • Purcell, S. et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am. J. Hum. Genet. 81, 559-575 (2007).
    • (2007) Am. J. Hum. Genet. , vol.81 , pp. 559-575
    • Purcell, S.1
  • 44
    • 84959801619 scopus 로고
    • Statistical aspects of the analysis of data from retrospective studies of disease
    • Mantel, N. & Haenszel, W. Statistical aspects of the analysis of data from retrospective studies of disease. J. Natl. Cancer Inst. 22, 719-748 (1959).
    • (1959) J. Natl. Cancer Inst. , vol.22 , pp. 719-748
    • Mantel, N.1    Haenszel, W.2
  • 45
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: Analysis and visualization of LD and haplotype maps
    • Barrett, J.C., Fry, B., Maller, J. & Daly, M.J. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 21, 263-265 (2005).
    • (2005) Bioinformatics , vol.21 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 46
    • 33749137515 scopus 로고    scopus 로고
    • A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC
    • de Bakker, P.I. et al. A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC. Nat. Genet. 38, 1166-1172 (2006).
    • (2006) Nat. Genet. , vol.38 , pp. 1166-1172
    • De Bakker, P.I.1
  • 47
    • 35348817330 scopus 로고    scopus 로고
    • Rapid and accurate haplotype phasing and missing-data inference for whole-genome association studies by use of localized haplotype clustering
    • Browning, S.R. & Browning, B.L. Rapid and accurate haplotype phasing and missing-data inference for whole-genome association studies by use of localized haplotype clustering. Am. J. Hum. Genet. 81, 1084-1097 (2007).
    • (2007) Am. J. Hum. Genet. , vol.81 , pp. 1084-1097
    • Browning, S.R.1    Browning, B.L.2


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