Plzf drives MLL-fusion–mediated leukemogenesis specifically in long-term hematopoietic stem cells

Blood

Volumn 122, Issue 7, 2013, Pages 1271-1283

  Ono, Ryoichi ^a   Masuya, Masahiro ^a   Nakajima, Hideaki ^b   Enomoto, Yutaka ^c   Miyata, Eri ^a   Nakamura, Akihide ^a   Ishii, Satomi ^a   Suzuki, Kei ^a   Shibata Minoshima, Fumi ^c   Katayama, Naoyuki ^a   Kitamura, Toshio ^c   Nosaka, Tetsuya ^a  

^a MIE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c THE UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

HYBRID PROTEIN; MIXED LINEAGE LEUKEMIA ENL FUSION PROTEIN; MIXED LINEAGE LEUKEMIA PROTEIN; PROMYELOCYTIC LEUKEMIA ZINC FINGER PROTEIN; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR HOXA9; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; KRUPPEL LIKE FACTOR; MESSENGER RNA; MLL ENL ONCOPROTEIN, HUMAN; MLL-ENL ONCOPROTEIN, HUMAN; ONCOPROTEIN; TUMOR MARKER; ZBTB16 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL IMMORTALIZATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; FLUORESCENCE ACTIVATED CELL SORTING; FUSION GENE; GENE EXPRESSION; GENE SILENCING; HEMATOPOIETIC STEM CELL; IN VITRO STUDY; LEUKEMOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; PROTEIN FUNCTION; UPREGULATION; ANIMAL; C57BL MOUSE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL TRANSFORMATION; DNA MICROARRAY; DRUG ANTAGONISM; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GENETICS; HUMAN; LEUKEMIA; METABOLISM; MYELOID PROGENITOR CELL; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; RETROVIRUS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; HEMATOPOIETIC STEM CELLS; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; LEUKEMIA; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MYELOID PROGENITOR CELLS; MYELOID-LYMPHOID LEUKEMIA PROTEIN; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ONCOGENE PROTEINS, FUSION; REAL-TIME POLYMERASE CHAIN REACTION; RETROVIRIDAE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR MARKERS, BIOLOGICAL;

EID: 84887187453     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-09-456665     Document Type: Article

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