Suppression of autophagy dysregulates the antioxidant response and causes premature senescence of melanocytes

Journal of Investigative Dermatology

Volumn 135, Issue 5, 2015, Pages 1348-1357

  Zhang, Cheng Feng ^a,b   Gruber, Florian ^a   Ni, Chunya ^a,b   Mildner, Michael ^a   Koenig, Ulrich ^a   Karner, Susanne ^a   Barresi, Caterina ^a   Rossiter, Heidemarie ^a   Narzt, Marie Sophie ^a   Nagelreiter, Ionela M ^a   Larue, Lionel ^c,d   Tobin, Desmond J ^e   Eckhart, Leopold ^a   Tschachler, Erwin ^a  

^a Universitatsklinik fur Dermatologie   (Austria)

^b FUDAN UNIVERSITY   (China)

^c INSTITUT CURIE   (France)

^d Centre National de la Recherche Scientifique   (France)

^e UNIVERSITY OF BRADFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY PROTEIN 5; AUTOPHAGY PROTEIN 7; GLUTATHIONE TRANSFERASE M1; KI 67 ANTIGEN; MELANIN; MICROTUBULE ASSOCIATED PROTEIN 1; MICROTUBULE ASSOCIATED PROTEIN 1 LIGHT CHAIN 3 BETA; PROTEIN P62; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); TRANSCRIPTION FACTOR NRF2; UBIQUITINATED PROTEIN; UNCLASSIFIED DRUG; ANTIOXIDANT; ATG7 PROTEIN, MOUSE; MICROTUBULE ASSOCIATED PROTEIN; NFE2L2 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; ATG7 GENE; AUTOPHAGY; CELL AGING; CELL PROLIFERATION; CELL STRESS; CONTROLLED STUDY; FEMALE; GENE; GENE DELETION; GENE REPRESSION; GENETIC TRANSCRIPTION; GENOTYPE; HOMEOSTASIS; HUMAN; HUMAN CELL; HYPOPIGMENTATION; IN VITRO STUDY; LIGHT CHAIN; LIPID OXIDATION; LOXP SITE; MALE; MELANOCYTE; MELANOGENESIS; MELANOSOME; MOUSE; NONHUMAN; NORMAL HUMAN; OXIDATIVE STRESS; PREMATURE AGING; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SEX DIFFERENCE; SKIN PIGMENTATION; UPREGULATION; WESTERN BLOTTING; X CHROMOSOME; ANIMAL; CELL CULTURE; DEFICIENCY; GENETICS; KNOCKOUT MOUSE; LIPID PEROXIDATION; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

AGING, PREMATURE; ANIMALS; ANTIOXIDANTS; AUTOPHAGY; CELL AGING; CELL PROLIFERATION; CELLS, CULTURED; HOMEOSTASIS; HUMANS; IN VITRO TECHNIQUES; LIPID PEROXIDATION; MELANINS; MELANOCYTES; MICE; MICE, KNOCKOUT; MICROTUBULE-ASSOCIATED PROTEINS; MODELS, ANIMAL; NF-E2-RELATED FACTOR 2; REACTIVE OXYGEN SPECIES;

EID: 84928412253     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2014.439     Document Type: Article

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