Disarming pseudomonas aeruginosa virulence factor lasb by leveraging a caenorhabditis elegans infection model

Chemistry and Biology

Volumn 22, Issue 4, 2015, Pages 483-491

  Zhu, Jie ^a   Cai, Xiaoqing ^a   Harris, Tyler L ^a   Gooyit, Major ^a   Wood, Malcolm ^a   Lardy, Matthew ^b   Janda, Kim D ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b Genentech   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETAMIDE; ACETAMIDE DERIVATIVE; BACTERIAL PROTEIN; METALLOPROTEINASE; PRODRUG; PSEUDOLYSIN, PSEUDOMONAS AERUGINOSA; THIOL DERIVATIVE; VIRULENCE FACTOR;

ANIMAL; ANTAGONISTS AND INHIBITORS; BINDING SITE; CAENORHABDITIS ELEGANS; CHEMISTRY; DISEASE MODEL; DRUG EFFECTS; ENZYME ACTIVE SITE; GENETICS; METABOLISM; MICROBIOLOGY; MOLECULAR DOCKING; PHYSIOLOGY; PSEUDOMONAS AERUGINOSA; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TRANSMISSION ELECTRON MICROSCOPY;

ACETAMIDES; ANIMALS; BACTERIAL PROTEINS; BINDING SITES; CAENORHABDITIS ELEGANS; CATALYTIC DOMAIN; DISEASE MODELS, ANIMAL; METALLOENDOPEPTIDASES; MICROSCOPY, ELECTRON, TRANSMISSION; MOLECULAR DOCKING SIMULATION; PRODRUGS; PSEUDOMONAS AERUGINOSA; STRUCTURE-ACTIVITY RELATIONSHIP; SULFHYDRYL COMPOUNDS; VIRULENCE FACTORS;

EID: 84928378898     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2015.03.012     Document Type: Article

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