Antagonism of a zinc metalloprotease using a unique metal-chelating scaffold: Tropolones as inhibitors of P. aeruginosa elastase

Chemical Communications

Volumn 49, Issue 31, 2013, Pages 3197-3199

  Fullagar, Jessica L ^a   Garner, Amanda L ^b   Struss, Anjali K ^b   Day, Joshua A ^a   Martin, David P ^a   Yu, Jing ^b   Cai, Xiaoqing ^b   Janda, Kim D ^b   Cohen, Seth M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ELASTASE; TROPOLONE DERIVATIVE;

ARTICLE; BACTERIAL VIRULENCE; CONTROLLED STUDY; DRUG POTENCY; ENZYME INHIBITION; IC 50; NONHUMAN; PSEUDOMONAS AERUGINOSA; SUBSTITUTION REACTION;

EID: 84875444608     PISSN: 13597345     EISSN: 1364548X     Source Type: Journal    
DOI: 10.1039/c3cc41191e     Document Type: Article

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