Dual protonophore-chitinase inhibitors dramatically affect O. Volvulus molting

Journal of Medicinal Chemistry

Volumn 57, Issue 13, 2014, Pages 5792-5799

  Gooyit, Major ^a   Tricoche, Nancy ^b   Lustigman, Sara ^b   Janda, Kim D ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b NEW YORK BLOOD CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXY 3,5 DIIODO N (4 PHENOXYPHENYL)BENZAMIDE; 2 HYDROXY 3,5 DIIODO N (NAPHTHALEN 2 YL)BENZAMIDE; 2 HYDROXY 3,5 DIIODO N METHYL N (4 PHENOXYPHENYL)BENZAMIDE; 2 HYDROXY 3,5 DIIODO N [4 (PARA TOLYLOXY)PHENYL]BENZAMIDE; 2 HYDROXY 3,5 DIIODO N [4' METHYL (1,1' BIPHENYL) 4 YL]BENZAMIDE; 3,5 DIIODO 2 METHOXY N (4 PHENOXYPHENYL)BENZAMIDE; 3,5 DIIODO 2 METHOXY N (NAPHTHALEN 2 YL)BENZAMIDE; 3,5 DIIODO 2 METHOXY N METHYL N (4 PHENOXYPHENYL)BENZAMIDE; 3,5 DIIODO 2 METHOXYBENZOIC ACID; 3,5 DIIODO N (4 PHENOXYPHENYL)BENZAMIDE; 3,5 DIIODO N (NAPHTHALEN 2 YL)BENZAMIDE; ANTINEMATODAL AGENT; CHITINASE; CHITINASE INHIBITOR; CLOSANTEL; N METHYL 4 PHENOXYANILINE; N [(1,1' BIPHENYL) 4 YL] 2 HYDROXY 3,5 DIIODOBENZAMIDE; N [2 (1H INDOL 3 YL)ETHYL] 2 HYDROXY 3,5 DIIODOBENZAMIDE; N [4 (2 CHLOROPHENOXY)PHENYL] 2 HYDROXY 3,5 DIIODOBENZAMIDE; N [4 (3 CHLOROPHENOXY)PHENYL] 2 HYDROXY 3,5 DIIODOBENZAMIDE; N [4 (4 CHLOROPHENOXY)PHENYL] 2 HYDROXY 3,5 DIIODOBENZAMIDE; N [4 (4 CHLOROPHENOXY)PHENYL] 3,5 DIIODO 2 METHOXYBENZAMIDE; N [4 (4 CHLOROPHENOXY)PHENYL] 3,5 DIIODOBENZAMIDE; N [4 (4 FLUOROPHENOXY)PHENYL] 2 HYDROXY 3,5 DIIODOBENZAMIDE; N [4' CHLORO (1,1' BIPHENYL) 4 YL] 2 HYDROXY 3,5 DIIODOBENZAMIDE; UNCLASSIFIED DRUG;

ANTHELMINTIC ACTIVITY; ARTICLE; DRUG BINDING; HUMAN; HUMAN CELL; IC 50; MOLTING; NONHUMAN; ONCHOCERCA VOLVULUS; ONCHOCERCIASIS; OXIDATIVE PHOSPHORYLATION UNCOUPLING;

ANIMALS; ANTINEMATODAL AGENTS; CAENORHABDITIS ELEGANS; CHITINASE; ENZYME INHIBITORS; IONOPHORES; MOLTING; ONCHOCERCA VOLVULUS; ONCHOCERCIASIS; SALICYLANILIDES; STRUCTURE-ACTIVITY RELATIONSHIP; UNCOUPLING AGENTS;

EID: 84904365342     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm5006435     Document Type: Article

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