A Zap70-dependent feedback circuit is essential for efficient selection of CD4 lineage thymocytes

Immunology and Cell Biology

Volumn 93, Issue 4, 2015, Pages 406-416

  Sinclair, Charles ^a   Ono, Masahiro ^b   Seddon, Benedict ^c  

^a EMORY UNIVERSITY   (United States)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c ROYAL FREE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN KINASE ZAP 70; T LYMPHOCYTE RECEPTOR; HLA ANTIGEN CLASS 2; LYMPHOCYTE ANTIGEN RECEPTOR; ZAP70 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CD4+ T LYMPHOCYTE; CELL MATURATION; CELL SURVIVAL; CHIMERA; CONTROLLED STUDY; FEEDBACK SYSTEM; GENETIC ANALYSIS; IN VIVO STUDY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; THYMOCYTE; ANIMAL; C57BL MOUSE; CD8+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL LINEAGE; GENE EXPRESSION REGULATION; GENETICS; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

MUS;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELL LINEAGE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HISTOCOMPATIBILITY ANTIGENS CLASS II; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; THYMOCYTES; ZAP-70 PROTEIN-TYROSINE KINASE;

EID: 84928209373     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/icb.2014.107     Document Type: Article

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