The long-term survival potential of mature T lymphocytes is programmed during development in the thymus

Science Signaling

Volumn 4, Issue 199, 2011, Pages

  Sinclair, Charles ^a   Saini, Manoj ^a,c   Van Der Loeff, Ina Schim ^a   Sakaguchi, Shimon ^b   Seddon, Benedict ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^b KYOTO UNIVERSITY   (Japan)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOHEXIMIDE; CYCLOSPORIN; INTERLEUKIN 7; INTERLEUKIN 7 RECEPTOR ALPHA; IONOMYCIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE; PHORBOL 13 ACETATE 12 MYRISTATE; RAPAMYCIN; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR RUNX3; UO 126; INTERLEUKIN 7 RECEPTOR; LYMPHOCYTE ANTIGEN RECEPTOR;

ANIMAL CELL; ARTICLE; BONE MARROW; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL SURVIVAL; CELLULAR IMMUNITY; CHIMERA; CONTROLLED STUDY; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; IMMUNE SYSTEM; MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; THYMOCYTE; THYMUS; TRANSGENIC MOUSE; ANIMAL; BIOSYNTHESIS; CYTOLOGY; GENETICS; IMMUNOLOGY; METABOLISM; MOUSE MUTANT;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL SURVIVAL; GENE EXPRESSION REGULATION; MICE; MICE, KNOCKOUT; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, INTERLEUKIN-7; SIGNAL TRANSDUCTION; THYMOCYTES; THYMUS GLAND;

EID: 81455138162     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2002246     Document Type: Article

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