메뉴 건너뛰기




Volumn 47, Issue 2, 2015, Pages 123-132

Endogenous ways to stimulate brown adipose tissue in humans

Author keywords

Anti obesity therapy; Beige adipocytes; Brown adipose tissue; Endocrine factors; Non shivering thermogenesis; Paracrine factors; UCP1

Indexed keywords

ATRIAL NATRIURETIC FACTOR; BILE ACID; BONE MORPHOGENETIC PROTEIN; BRAIN NATRIURETIC PEPTIDE; FIBROBLAST GROWTH FACTOR 21; INSULIN; IRISIN; RETINOIC ACID; THYROID HORMONE; VASCULOTROPIN;

EID: 84928169516     PISSN: 07853890     EISSN: 13652060     Source Type: Journal    
DOI: 10.3109/07853890.2013.874663     Document Type: Article
Times cited : (24)

References (101)
  • 3
    • 0347989317 scopus 로고    scopus 로고
    • Brown adipose tissue: Function and physiological significance
    • Cannon B, Nedergaard J. Brown adipose tissue: function and physiological significance. Physiol Rev. 2004; 84: 277-359.
    • (2004) Physiol Rev. , vol.84 , pp. 277-359
    • Cannon, B.1    Nedergaard, J.2
  • 5
    • 0032549811 scopus 로고    scopus 로고
    • A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
    • Puigserver P, Wu Z, Park CW, Graves R, Wright M, Spiegelman BM. A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell. 1998; 92: 829-39.
    • (1998) Cell , vol.92 , pp. 829-839
    • Puigserver, P.1    Wu, Z.2    Park, C.W.3    Graves, R.4    Wright, M.5    Spiegelman, B.M.6
  • 7
    • 0642345828 scopus 로고    scopus 로고
    • Patterns of (18)F-FDG uptake in adipose tissue and muscle: A potential source of false-positives for PET
    • Yeung HW, Grewal RK, Gonen M, Schoder H, Larson SM. Patterns of (18)F-FDG uptake in adipose tissue and muscle: a potential source of false-positives for PET. J Nucl Med. 2003; 44: 1789-96.
    • (2003) J Nucl Med. , vol.44 , pp. 1789-1796
    • Yeung, H.W.1    Grewal, R.K.2    Gonen, M.3    Schoder, H.4    Larson, S.M.5
  • 10
    • 79959591690 scopus 로고    scopus 로고
    • Radiation dose at coronary CT angiography: Second-generation dual-source CT versus single-source 64-MDCT and first-generation dual-source CT. AJR
    • Fink C, Krissak R, Henzler T, Lechel U, Brix G, Takx RA, et al. Radiation dose at coronary CT angiography: second-generation dual-source CT versus single-source 64-MDCT and first-generation dual-source CT. AJR. Am J Roentgenol. 2011; 196: W550-7.
    • (2011) Am J Roentgenol. , vol.196 , pp. W550-W557
    • Fink, C.1    Krissak, R.2    Henzler, T.3    Lechel, U.4    Brix, G.5    Takx, R.A.6
  • 11
    • 84873545834 scopus 로고    scopus 로고
    • Combining 123I-metaiodobenzylguanidine SPECT/CT and 18F-FDG PET/CT for the assessment of brown adipose tissue activity in humans during cold exposure
    • Admiraal WM, Holleman F, Bahler L, Soeters MR, Hoekstra JB, Verberne HJ. Combining 123I-metaiodobenzylguanidine SPECT/CT and 18F-FDG PET/CT for the assessment of brown adipose tissue activity in humans during cold exposure. J Nucl Med. 2013; 54: 208-12.
    • (2013) J Nucl Med. , vol.54 , pp. 208-212
    • Admiraal, W.M.1    Holleman, F.2    Bahler, L.3    Soeters, M.R.4    Hoekstra, J.B.5    Verberne, H.J.6
  • 12
    • 84883829656 scopus 로고    scopus 로고
    • In vivo noninvasive detection of brown adipose tissue through intermolecular zero-quantum MRI
    • Branca RT, Zhang L, Warren WS, Auerbach E, Khanna A, Degan S, et al. In vivo noninvasive detection of brown adipose tissue through intermolecular zero-quantum MRI. PLoS One. 2013; 8: e74206.
    • (2013) PLoS One , vol.8 , pp. e74206
    • Branca, R.T.1    Zhang, L.2    Warren, W.S.3    Auerbach, E.4    Khanna, A.5    Degan, S.6
  • 13
    • 84883826071 scopus 로고    scopus 로고
    • Comparison of brown and white adipose tissues in infants and children with chemical-shift-encoded water-fat MRI
    • Hu H H, Yin L, Aggabao P C, Perkins T G, Chia J M, Gilsanz V. Comparison of brown and white adipose tissues in infants and children with chemical-shift-encoded water-fat MRI. J Magn Reson Imaging. 2013; 38: 885-96.
    • (2013) J Magn Reson Imaging. , vol.38 , pp. 885-896
    • Hu, H.H.1    Yin, L.2    Aggabao, P.C.3    Perkins, T.G.4    Chia, J.M.5    Gilsanz, V.6
  • 15
    • 84879993961 scopus 로고    scopus 로고
    • Brown fat activation mediates cold-induced thermogenesis in adult humans in response to a mild decrease in ambient temperature
    • Chen KY, Brychta RJ, Linderman JD, Smith S, Courville A, Dieckmann W, et al. Brown fat activation mediates cold-induced thermogenesis in adult humans in response to a mild decrease in ambient temperature. J Clin Endocrinol Metab. 2013; 98: E1218-23.
    • (2013) J Clin Endocrinol Metab. , vol.98 , pp. E1218-E1223
    • Chen, K.Y.1    Brychta, R.J.2    Linderman, J.D.3    Smith, S.4    Courville, A.5    Dieckmann, W.6
  • 17
    • 78449266620 scopus 로고    scopus 로고
    • Positive and negative control of Ucp1 gene transcription and the role of beta-adrenergic signaling networks
    • Collins S, Yehuda-Shnaidman E, Wang H. Positive and negative control of Ucp1 gene transcription and the role of beta-adrenergic signaling networks. Int J Obes (Lond). 2010; 34(Suppl 1): S28-33.
    • (2010) Int J Obes (Lond) , vol.34 , pp. S28-33
    • Collins, S.1    Yehuda-Shnaidman, E.2    Wang, H.3
  • 18
    • 84860506923 scopus 로고    scopus 로고
    • Anterograde transneuronal viral tract tracing reveals central sensory circuits from brown fat and sensory denervation alters its thermogenic responses
    • Vaughan CH, Bartness TJ. Anterograde transneuronal viral tract tracing reveals central sensory circuits from brown fat and sensory denervation alters its thermogenic responses. Am J Physiol Regul Integr Comp Physiol. 2012; 302: R1049-58.
    • (2012) Am J Physiol Regul Integr Comp Physiol. , vol.302 , pp. R1049-R1058
    • Vaughan, C.H.1    Bartness, T.J.2
  • 19
    • 2942595922 scopus 로고    scopus 로고
    • Identification of sympathetic premotor neurons in medullary raphe regions mediating fever and other thermoregulatory functions
    • Nakamura K, Matsumura K, Hubschle T, Nakamura Y, Hioki H, Fujiyama F, et al. Identification of sympathetic premotor neurons in medullary raphe regions mediating fever and other thermoregulatory functions. J Neurosci. 2004; 24: 5370-80.
    • (2004) J Neurosci. , vol.24 , pp. 5370-5380
    • Nakamura, K.1    Matsumura, K.2    Hubschle, T.3    Nakamura, Y.4    Hioki, H.5    Fujiyama, F.6
  • 20
    • 33751313602 scopus 로고    scopus 로고
    • Serotonin potentiates sympathetic responses evoked by spinal NMDA
    • Madden CJ, Morrison SF. Serotonin potentiates sympathetic responses evoked by spinal NMDA. J Physiol. 2006; 577: 525-37.
    • (2006) J Physiol. , vol.577 , pp. 525-537
    • Madden, C.J.1    Morrison, S.F.2
  • 21
    • 77749328955 scopus 로고    scopus 로고
    • Endogenous activation of spinal 5-hydroxytryptamine (5-HT) receptors contributes to the thermoregulatory activation of brown adipose tissue
    • Madden CJ, Morrison SF. Endogenous activation of spinal 5-hydroxytryptamine (5-HT) receptors contributes to the thermoregulatory activation of brown adipose tissue. Am J Physiol Regul Integr Comp Physiol. 2010; 298: R776-83.
    • (2010) Am J Physiol Regul Integr Comp Physiol. , vol.298 , pp. R776-R783
    • Madden, C.J.1    Morrison, S.F.2
  • 22
    • 38349106434 scopus 로고    scopus 로고
    • The effect of catecholamines on the glucose uptake in brown adipose tissue demonstrated by (18)F-FDG PET/CT in a patient with adrenal pheochromocytoma
    • Yamaga LY, Thom AF, Wagner J, Baroni RH, Hidal JT, Funari MG. The effect of catecholamines on the glucose uptake in brown adipose tissue demonstrated by (18)F-FDG PET/CT in a patient with adrenal pheochromocytoma. Eur J Nucl Med Mol Imaging. 2008; 35: 446-7.
    • (2008) Eur J Nucl Med Mol Imaging. , vol.35 , pp. 446-447
    • Yamaga, L.Y.1    Thom, A.F.2    Wagner, J.3    Baroni, R.H.4    Hidal, J.T.5    Funari, M.G.6
  • 23
    • 34247485758 scopus 로고    scopus 로고
    • Low-dose oral propranolol could reduce brown adipose tissue F-18 FDG uptake in patients undergoing PET scans
    • Parysow O, Mollerach AM, Jager V, Racioppi S, San Roman J, Gerbaudo VH. Low-dose oral propranolol could reduce brown adipose tissue F-18 FDG uptake in patients undergoing PET scans. Clin Nucl Med. 2007; 32: 351-7.
    • (2007) Clin Nucl Med. , vol.32 , pp. 351-357
    • Parysow, O.1    Mollerach, A.M.2    Jager, V.3    Racioppi, S.4    San Roman, J.5    Gerbaudo, V.H.6
  • 25
    • 84868206600 scopus 로고    scopus 로고
    • Systemic beta-adrenergic stimulation of thermogenesis is not accompanied by brown adipose tissue activity in humans
    • Vosselman MJ, van der Lans AA, Brans B, Wierts R, van Baak MA, Schrauwen P, et al. Systemic beta-adrenergic stimulation of thermogenesis is not accompanied by brown adipose tissue activity in humans. Diabetes. 2012; 61: 3106-13.
    • (2012) Diabetes , vol.61 , pp. 3106-3113
    • Vosselman, M.J.1    Van Der-Lans, A.A.2    Brans, B.3    Wierts, R.4    Van Baak, M.A.5    Schrauwen, P.6
  • 26
    • 0029740648 scopus 로고    scopus 로고
    • Neuroendocrine and autonomous mechanisms underlying thermoregulation in cold environment
    • Arancibia S, Rage F, Astier H, Tapia-Arancibia L. Neuroendocrine and autonomous mechanisms underlying thermoregulation in cold environment. Neuroendocrinology. 1996; 64: 257-67.
    • (1996) Neuroendocrinology. , vol.64 , pp. 257-267
    • Arancibia, S.1    Rage, F.2    Astier, H.3    Tapia-Arancibia, L.4
  • 27
    • 0036191639 scopus 로고    scopus 로고
    • Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases
    • Bianco AC, Salvatore D, Gereben B, Berry MJ, Larsen PR. Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases. Endocr Rev. 2002; 23: 38-89.
    • (2002) Endocr Rev. , vol.23 , pp. 38-89
    • Bianco, A.C.1    Salvatore, D.2    Gereben, B.3    Berry, M.J.4    Larsen, P.R.5
  • 28
    • 0035185505 scopus 로고    scopus 로고
    • The type 2 iodothyronine deiodinase is essential for adaptive thermogenesis in brown adipose tissue
    • de Jesus LA, Carvalho SD, Ribeiro MO, Schneider M, Kim SW, Harney JW, et al. The type 2 iodothyronine deiodinase is essential for adaptive thermogenesis in brown adipose tissue. J Clin Invest. 2001; 108: 1379-85.
    • (2001) J Clin Invest. , vol.108 , pp. 1379-1385
    • De Jesus, L.A.1    Carvalho, S.D.2    Ribeiro, M.O.3    Schneider, M.4    Kim, S.W.5    Harney, J.W.6
  • 29
    • 79955717583 scopus 로고    scopus 로고
    • Extrathyroidal expression of TSH receptor
    • Williams G R. Extrathyroidal expression of TSH receptor. Ann Endocrinol (Paris). 2011; 72: 68-73.
    • (2011) Ann Endocrinol (Paris) , vol.72 , pp. 68-73
    • Williams, G.R.1
  • 31
    • 79953225879 scopus 로고    scopus 로고
    • Disruption of thyroid hormone activation in type 2 deiodinase knockout mice causes obesity with glucose intolerance and liver steatosis only at thermoneutrality
    • Castillo M, Hall JA, Correa-Medina M, Ueta C, Kang HW, Cohen DE, et al. Disruption of thyroid hormone activation in type 2 deiodinase knockout mice causes obesity with glucose intolerance and liver steatosis only at thermoneutrality. Diabetes. 2011; 60: 1082-9.
    • (2011) Diabetes , vol.60 , pp. 1082-1089
    • Castillo, M.1    Hall, J.A.2    Correa-Medina, M.3    Ueta, C.4    Kang, H.W.5    Cohen, D.E.6
  • 33
    • 75149193049 scopus 로고    scopus 로고
    • Thyroid hormone induced brown adipose tissue and amelioration of diabetes in a patient with extreme insulin resistance
    • Skarulis MC, Celi FS, Mueller E, Zemskova M, Malek R, Hugendubler L, et al. Thyroid hormone induced brown adipose tissue and amelioration of diabetes in a patient with extreme insulin resistance. J Clin Endocrinol Metab. 2010; 95: 256-62.
    • (2010) J Clin Endocrinol Metab. , vol.95 , pp. 256-262
    • Skarulis, M.C.1    Celi, F.S.2    Mueller, E.3    Zemskova, M.4    Malek, R.5    Hugendubler, L.6
  • 34
    • 0036317754 scopus 로고    scopus 로고
    • Association between a novel variant of the human type 2 deiodinase gene Thr92Ala and insulin resistance: Evidence of interaction with the Trp64Arg variant of the beta-3-adrenergic receptor
    • Mentuccia D, P roietti-Pannunzi L, Tanner K, Bacci V, Pollin T I, Poehlman ET, et al. Association between a novel variant of the human type 2 deiodinase gene Thr92Ala and insulin resistance: evidence of interaction with the Trp64Arg variant of the beta-3-adrenergic receptor. Diabetes. 2002; 51: 880-3.
    • (2002) Diabetes , vol.51 , pp. 880-883
    • Mentuccia, D.1    Roietti-Pannunzi, L.P.2    Tanner, K.3    Bacci, V.4    Pollin, T.I.5    Poehlman, E.T.6
  • 35
    • 77956433431 scopus 로고    scopus 로고
    • Thyroid hormones: Igniting brown fat via the brain
    • Cannon B, Nedergaard J. Thyroid hormones: igniting brown fat via the brain. Nat Med. 2010; 16: 965-7.
    • (2010) Nat Med. , vol.16 , pp. 965-967
    • Cannon, B.1    Nedergaard, J.2
  • 36
    • 0023145116 scopus 로고
    • Thermogenic capacity and brown fat in rats exercise-trained by running
    • Wickler SJ, Stern JS, Glick Z, Horwitz BA. Thermogenic capacity and brown fat in rats exercise-trained by running. Metabolism. 1987; 36: 76-81.
    • (1987) Metabolism. , vol.36 , pp. 76-81
    • Wickler, S.J.1    Stern, J.S.2    Glick, Z.3    Horwitz, B.A.4
  • 37
  • 38
    • 84864283300 scopus 로고    scopus 로고
    • Muscles, exercise and obesity: Skeletal muscle as a secretory organ
    • Pedersen BK, Febbraio MA. Muscles, exercise and obesity: skeletal muscle as a secretory organ. Nat Rev Endocrinol. 2012; 8: 457-65.
    • (2012) Nat Rev Endocrinol. , vol.8 , pp. 457-465
    • Pedersen, B.K.1    Febbraio, M.A.2
  • 39
    • 84862776702 scopus 로고    scopus 로고
    • A PGC1-alpha-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
    • Bostrom P, Wu J, Jedrychowski MP, Korde A, Ye L, Lo JC, et al. A PGC1-alpha-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature. 2012; 481: 463-8.
    • (2012) Nature , vol.481 , pp. 463-468
    • Bostrom, P.1    Wu, J.2    Jedrychowski, M.P.3    Korde, A.4    Ye, L.5    Lo, J.C.6
  • 41
    • 0028090259 scopus 로고
    • Influence of exercise training and age on uncoupling protein mRNA expression in brown adipose tissue
    • Scarpace PJ, Yenice S, Tumer N. Influence of exercise training and age on uncoupling protein mRNA expression in brown adipose tissue. Pharmacol Biochem Behav. 1994; 49: 1057-9.
    • (1994) Pharmacol Biochem Behav. , vol.49 , pp. 1057-1059
    • Scarpace, P.J.1    Yenice, S.2    Tumer, N.3
  • 42
  • 44
    • 84863229962 scopus 로고    scopus 로고
    • Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes
    • Bordicchia M, Liu D, Amri EZ, Ailhaud G, Dessì-Fulgheri P, Zhang C, et al. Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes. J Clin Invest. 2012; 122: 1022-36.
    • (2012) J Clin Invest. , vol.122 , pp. 1022-1036
    • Bordicchia, M.1    Liu, D.2    Amri, E.Z.3    Ailhaud, G.4    Dessì-Fulgheri, P.5    Zhang, C.6
  • 45
    • 84873319246 scopus 로고    scopus 로고
    • Natriuretic peptides and cGMP signaling control of energy homeostasis
    • Moro C, Lafontan M. Natriuretic peptides and cGMP signaling control of energy homeostasis. Am J Physiol Heart Circ Physiol. 2013; 304: H358-68.
    • (2013) Am J Physiol Heart Circ Physiol. , vol.304 , pp. H358-H368
    • Moro, C.1    Lafontan, M.2
  • 47
    • 26944446917 scopus 로고    scopus 로고
    • Impact of body mass and body composition on circulating levels of natriuretic peptides: Results from the Dallas Heart Study
    • Das SR, Drazner MH, Dries DL, Vega GL, Stanek HG, Abdullah SM, et al. Impact of body mass and body composition on circulating levels of natriuretic peptides: results from the Dallas Heart Study. Circulation. 2005; 112: 2163-8.
    • (2005) Circulation , vol.112 , pp. 2163-2168
    • Das, S.R.1    Drazner, M.H.2    Dries, D.L.3    Vega, G.L.4    Stanek, H.G.5    Abdullah, S.M.6
  • 48
    • 84863022943 scopus 로고    scopus 로고
    • Low plasma level of atrial natriuretic peptide predicts development of diabetes: The prospective Malmo Diet and Cancer study
    • Magnusson M, Jujic A, Hedblad B, Engström G, Persson M, Struck J, et al. Low plasma level of atrial natriuretic peptide predicts development of diabetes: the prospective Malmo Diet and Cancer study. J Clin Endocrinol Metab. 2012; 97: 638-45.
    • (2012) J Clin Endocrinol Metab. , vol.97 , pp. 638-645
    • Magnusson, M.1    Jujic, A.2    Hedblad, B.3    Engström, G.4    Persson, M.5    Struck, J.6
  • 49
    • 1342295716 scopus 로고    scopus 로고
    • Involvement of a cGMP-dependent pathway in the natriuretic peptide-mediated hormone-sensitive lipase phosphorylation in human adipocytes
    • Sengenes C, Bouloumie A, Hauner H, Berlan M, Busse R, Lafontan M, et al. Involvement of a cGMP-dependent pathway in the natriuretic peptide-mediated hormone-sensitive lipase phosphorylation in human adipocytes. J Biol Chem. 2003; 278: 48617-26.
    • (2003) J Biol Chem. , vol.278 , pp. 48617-48626
    • Sengenes, C.1    Bouloumie, A.2    Hauner, H.3    Berlan, M.4    Busse, R.5    Lafontan, M.6
  • 50
    • 29044440372 scopus 로고    scopus 로고
    • Signalling mechanisms regulating lipolysis
    • Carmen GY, Victor SM. Signalling mechanisms regulating lipolysis. Cell Signal. 2006; 18: 401-8.
    • (2006) Cell Signal. , vol.18 , pp. 401-408
    • Carmen, G.Y.1    Victor, S.M.2
  • 52
    • 77953809603 scopus 로고    scopus 로고
    • Metabolic consequences of the presence or absence of the thermogenic capacity of brown adipose tissue in mice (and probably in humans)
    • Cannon B, Nedergaard J. Metabolic consequences of the presence or absence of the thermogenic capacity of brown adipose tissue in mice (and probably in humans). Int J Obes (Lond). 2010; 34(Suppl 1): S7-16.
    • (2010) Int J Obes (Lond) , vol.34 , pp. S7-16
    • Cannon, B.1    Nedergaard, J.2
  • 53
    • 17844363526 scopus 로고    scopus 로고
    • Uncoupling protein 1 is necessary for norepinephrine induced glucose utilization in brown adipose tissue
    • Inokuma K, O gura-Okamatsu Y, Toda C, Kimura K, Yamashita H, Saito M. Uncoupling protein 1 is necessary for norepinephrine induced glucose utilization in brown adipose tissue. Diabetes. 2005; 54: 1385-91.
    • (2005) Diabetes , vol.54 , pp. 1385-1391
    • Inokuma, K.1    Gura-Okamatsu, Y.O.2    Toda, C.3    Kimura, K.4    Yamashita, H.5    Saito, M.6
  • 54
    • 0018746850 scopus 로고
    • The physiological role of pyruvate carboxylation in hamster brown adipose tissue
    • Cannon B, Nedergaard J. The physiological role of pyruvate carboxylation in hamster brown adipose tissue. Eur J Biochem. 1979; 94: 419-26.
    • (1979) Eur J Biochem. , vol.94 , pp. 419-426
    • Cannon, B.1    Nedergaard, J.2
  • 55
    • 0026046158 scopus 로고
    • Major thermogenic defect associated with insulin resistance in brown adipose tissue of obese diabetic SHR/N-cp rats
    • Marette A, Deshaies Y, Collet AJ, Tulp O, Bukowiecki LJ. Major thermogenic defect associated with insulin resistance in brown adipose tissue of obese diabetic SHR/N-cp rats. Am J Physiol. 1991; 261(2 Pt 1): E204-13.
    • (1991) Am J Physiol. , vol.261 , Issue.2 , pp. E204-E213
    • Marette, A.1    Deshaies, Y.2    Collet, A.J.3    Tulp, O.4    Bukowiecki, L.J.5
  • 56
    • 0024831575 scopus 로고
    • Brown adipose tissue thermogenesis and obesity
    • Himms-Hagen J. Brown adipose tissue thermogenesis and obesity. Prog Lipid Res. 1989; 28: 67-115.
    • (1989) Prog Lipid Res. , vol.28 , pp. 67-115
    • Himms-Hagen, J.1
  • 57
    • 78650098848 scopus 로고    scopus 로고
    • Outdoor temperature, age, sex, body mass index, and diabetic status determine the prevalence, mass, and glucose-uptake activity of 18F-FDG-detected BAT in humans
    • Ouellet V, Routhier-Labadie A, Bellemare W, Lakhal-Chaieb L, Turcotte E, Carpentier AC, et al. Outdoor temperature, age, sex, body mass index, and diabetic status determine the prevalence, mass, and glucose-uptake activity of 18F-FDG-detected BAT in humans. J Clin Endocrinol Metab. 2011; 96: 192-9.
    • (2011) J Clin Endocrinol Metab. , vol.96 , pp. 192-199
    • Ouellet, V.1    Routhier-Labadie, A.2    Bellemare, W.3    Lakhal-Chaieb, L.4    Turcotte, E.5    Carpentier, A.C.6
  • 58
    • 84855661101 scopus 로고    scopus 로고
    • The relationship between patients' serum glucose levels and metabolically active brown adipose tissue detected by PET/CT
    • Jacene HA, Cohade CC, Zhang Z, Wahl RL. The relationship between patients' serum glucose levels and metabolically active brown adipose tissue detected by PET/CT. Mol Imaging Biol. 2011; 13: 1278-83.
    • (2011) Mol Imaging Biol. , vol.13 , pp. 1278-1283
    • Jacene, H.A.1    Cohade, C.C.2    Zhang, Z.3    Wahl, R.L.4
  • 61
    • 0023203504 scopus 로고
    • Cold exposure potentiates the effect of insulin on in vivo glucose uptake
    • Vallerand AL, Perusse F, Bukowiecki LJ. Cold exposure potentiates the effect of insulin on in vivo glucose uptake. Am J Physiol. 1987; 253(2 Pt 1): E179-86.
    • (1987) Am J Physiol. , vol.253 , Issue.2 , pp. E179-E186
    • Vallerand, A.L.1    Perusse, F.2    Bukowiecki, L.J.3
  • 62
    • 79960945989 scopus 로고    scopus 로고
    • Different metabolic responses of human brown adipose tissue to activation by cold and insulin
    • Orava J, Nuutila P, Lidell ME, Oikonen V, Noponen T, Viljanen T, et al. Different metabolic responses of human brown adipose tissue to activation by cold and insulin. Cell Metab. 2011; 14: 272-9.
    • (2011) Cell Metab. , vol.14 , pp. 272-279
    • Orava, J.1    Nuutila, P.2    Lidell, M.E.3    Oikonen, V.4    Noponen, T.5    Viljanen, T.6
  • 63
    • 0034697846 scopus 로고    scopus 로고
    • Identification of a novel FGF, FGF-21, preferentially expressed in the liver
    • Nishimura T, Nakatake Y, Konishi M, Itoh N. Identification of a novel FGF, FGF-21, preferentially expressed in the liver. Biochim Biophys Acta. 2000; 1492: 203-6.
    • (2000) Biochim Biophys Acta. , vol.1492 , pp. 203-206
    • Nishimura, T.1    Nakatake, Y.2    Konishi, M.3    Itoh, N.4
  • 67
    • 61649127208 scopus 로고    scopus 로고
    • Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice
    • Xu J, Lloyd DJ, Hale C, Stanislaus S, Chen M, Sivits G, et al. Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice. Diabetes. 2009; 58: 250-9.
    • (2009) Diabetes , vol.58 , pp. 250-259
    • Xu, J.1    Lloyd, D.J.2    Hale, C.3    Stanislaus, S.4    Chen, M.5    Sivits, G.6
  • 68
    • 79953886306 scopus 로고    scopus 로고
    • Thermogenic activation induces FGF21 expression and release in brown adipose tissue
    • Hondares E, Iglesias R, Giralt A, Gonzalez FJ, Giralt M, Mampel T, et al. Thermogenic activation induces FGF21 expression and release in brown adipose tissue. J Biol Chem. 2011; 286: 12983-90.
    • (2011) J Biol Chem. , vol.286 , pp. 12983-12990
    • Hondares, E.1    Iglesias, R.2    Giralt, A.3    Gonzalez, F.J.4    Giralt, M.5    Mampel, T.6
  • 69
    • 84860824001 scopus 로고    scopus 로고
    • Cell biology. FG F 21 takes a fat bite
    • Canto C, Auwerx J. Cell biology. FG F 21 takes a fat bite. Science. 2012 ;336: 675-6.
    • (2012) Science , vol.336 , pp. 675-676
    • Canto, C.1    Auwerx, J.2
  • 70
    • 0033538473 scopus 로고    scopus 로고
    • Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1
    • Wu Z, Puigserver P, Andersson U, Zhang C, Adelmant G, Mootha V, et al. Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell. 1999; 98: 115-24.
    • (1999) Cell , vol.98 , pp. 115-124
    • Wu, Z.1    Puigserver, P.2    Andersson, U.3    Zhang, C.4    Adelmant, G.5    Mootha, V.6
  • 71
    • 84872070199 scopus 로고    scopus 로고
    • Mild cold exposure modulates fibroblast growth factor 21 (FGF21) diurnal rhythm in humans: Relationship between FGF21 levels, lipolysis, and cold-induced thermogenesis
    • Lee P, Brychta RJ, Linderman J, Smith S, Chen KY, Celi FS. Mild cold exposure modulates fibroblast growth factor 21 (FGF21) diurnal rhythm in humans: relationship between FGF21 levels, lipolysis, and cold-induced thermogenesis. J Clin Endocrinol Metab. 2013; 98: E98-102.
    • (2013) J Clin Endocrinol Metab. , vol.98 , pp. E98-102
    • Lee, P.1    Brychta, R.J.2    Linderman, J.3    Smith, S.4    Chen, K.Y.5    Celi, F.S.6
  • 72
    • 84863116228 scopus 로고    scopus 로고
    • Fibroblast growth factor 21 promotes bone loss by potentiating the effects of peroxisome proliferator-activated receptor gamma
    • Wei W, Dutchak PA, Wang X, Ding X, Wang X, Bookout AL, et al. Fibroblast growth factor 21 promotes bone loss by potentiating the effects of peroxisome proliferator-activated receptor gamma. Proc Natl Acad Sci U S A. 2012; 109: 3143-8.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 3143-3148
    • Wei, W.1    Dutchak, P.A.2    Wang, X.3    Ding, X.4    Wang, X.5    Bookout, A.L.6
  • 73
    • 31444454037 scopus 로고    scopus 로고
    • Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation
    • Watanabe M, Houten SM, Mataki C, Christoffolete MA, Kim BW, Sato H, et al. Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation. Nature. 2006; 439: 484-9.
    • (2006) Nature , vol.439 , pp. 484-489
    • Watanabe, M.1    Houten, S.M.2    Mataki, C.3    Christoffolete, M.A.4    Kim, B.W.5    Sato, H.6
  • 74
    • 80052720863 scopus 로고    scopus 로고
    • TGR5: A novel target for weight maintenance and glucose metabolism
    • Chen X, Lou G, Meng Z, Huang W. TGR5: a novel target for weight maintenance and glucose metabolism. Exp Diabetes Res. 2011; 2011: 853501.
    • (2011) Exp Diabetes Res. , vol.2011 , pp. 853501
    • Chen, X.1    Lou, G.2    Meng, Z.3    Huang, W.4
  • 76
    • 58249110568 scopus 로고    scopus 로고
    • Role of bile acids and bile acid receptors in metabolic regulation
    • Lefebvre P, Cariou B, Lien F, Kuipers F, Staels B. Role of bile acids and bile acid receptors in metabolic regulation. Physiol Rev. 2009; 89: 147-91.
    • (2009) Physiol Rev. , vol.89 , pp. 147-191
    • Lefebvre, P.1    Cariou, B.2    Lien, F.3    Kuipers, F.4    Staels, B.5
  • 77
    • 0037790917 scopus 로고    scopus 로고
    • The enzymes, regulation, and genetics of bile acid synthesis
    • Russell DW. The enzymes, regulation, and genetics of bile acid synthesis. Annu Rev Biochem. 2003; 72: 137-74.
    • (2003) Annu Rev Biochem. , vol.72 , pp. 137-174
    • Russell, D.W.1
  • 78
    • 79960838523 scopus 로고    scopus 로고
    • Farnesoid X receptor deficiency improves glucose homeostasis in mouse models of obesity
    • Prawitt J, Abdelkarim M, Stroeve JH, Popescu I, Duez H, Velagapudi VR, et al. Farnesoid X receptor deficiency improves glucose homeostasis in mouse models of obesity. Diabetes. 2011; 60: 1861-71.
    • (2011) Diabetes , vol.60 , pp. 1861-1871
    • Prawitt, J.1    Abdelkarim, M.2    Stroeve, J.H.3    Popescu, I.4    Duez, H.5    Velagapudi, V.R.6
  • 79
    • 79960695556 scopus 로고    scopus 로고
    • Lowering bile acid pool size with a synthetic farnesoid X receptor (FXR) agonist induces obesity and diabetes through reduced energy expenditure
    • Watanabe M, Horai Y, Houten SM, Morimoto K, Sugizaki T, Arita E, et al. Lowering bile acid pool size with a synthetic farnesoid X receptor (FXR) agonist induces obesity and diabetes through reduced energy expenditure. J Biol Chem. 2011; 286: 26913-20.
    • (2011) J Biol Chem. , vol.286 , pp. 26913-26920
    • Watanabe, M.1    Horai, Y.2    Houten, S.M.3    Morimoto, K.4    Sugizaki, T.5    Arita, E.6
  • 81
    • 35748973876 scopus 로고    scopus 로고
    • Co-receptor requirements for fibroblast growth factor-19 signaling
    • Wu X, Ge H, Gupte J, Weiszmann J, Shimamoto G, Stevens J, et al. Co-receptor requirements for fibroblast growth factor-19 signaling. J Biol Chem. 2007; 282: 29069-72.
    • (2007) J Biol Chem. , vol.282 , pp. 29069-29072
    • Wu, X.1    Ge, H.2    Gupte, J.3    Weiszmann, J.4    Shimamoto, G.5    Stevens, J.6
  • 82
    • 18344394556 scopus 로고    scopus 로고
    • Transgenic mice expressing human fibroblast growth factor-19 display increased metabolic rate and decreased adiposity
    • Tomlinson E, Fu L, John L, Hultgren B, Huang X, Renz M, et al. Transgenic mice expressing human fibroblast growth factor-19 display increased metabolic rate and decreased adiposity. Endocrinology. 2002; 143: 1741-7.
    • (2002) Endocrinology , vol.143 , pp. 1741-1747
    • Tomlinson, E.1    Fu, L.2    John, L.3    Hultgren, B.4    Huang, X.5    Renz, M.6
  • 87
    • 3042759742 scopus 로고    scopus 로고
    • Commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineage
    • Tang QQ, Otto TC, Lane MD. Commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineage. Proc Natl Acad Sci U S A. 2004; 101: 9607-11.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 9607-9611
    • Tang, Q.Q.1    Otto, T.C.2    Lane, M.D.3
  • 88
    • 50049127055 scopus 로고    scopus 로고
    • New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure
    • Tseng YH, Kokkotou E, Schulz TJ, Huang TL, Winnay JN, Taniguchi CM, et al. New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure. Nature. 2008; 454: 1000-4.
    • (2008) Nature , vol.454 , pp. 1000-1004
    • Tseng, Y.H.1    Kokkotou, E.2    Schulz, T.J.3    Huang, T.L.4    Winnay, J.N.5    Taniguchi, C.M.6
  • 89
    • 84860850964 scopus 로고    scopus 로고
    • BMP8B increases brown adipose tissue thermogenesis through both central and peripheral actions
    • Whittle AJ, Carobbio S, Martins L, Slawik M, Hondares E, Vázquez MJ, et al. BMP8B increases brown adipose tissue thermogenesis through both central and peripheral actions. Cell. 2012; 149: 871-85.
    • (2012) Cell , vol.149 , pp. 871-885
    • Whittle, A.J.1    Carobbio, S.2    Martins, L.3    Slawik, M.4    Hondares, E.5    Vázquez, M.J.6
  • 90
    • 0032616999 scopus 로고    scopus 로고
    • Retinoic acid: Its biosynthesis and metabolism
    • Napoli JL. Retinoic acid: its biosynthesis and metabolism. Prog Nucleic Acid Res Mol Biol. 1999; 63: 139-88.
    • (1999) Prog Nucleic Acid Res Mol Biol. , vol.63 , pp. 139-188
    • Napoli, J.L.1
  • 91
    • 37549038650 scopus 로고    scopus 로고
    • Retinoid metabolism and nuclear receptor responses: New insights into coordinated regulation of the PPAR-RXR complex
    • Ziouzenkova O, Plutzky J. Retinoid metabolism and nuclear receptor responses: new insights into coordinated regulation of the PPAR-RXR complex. FEBS Lett. 2008; 582: 32-38.
    • (2008) FEBS Lett. , vol.582 , pp. 32-38
    • Ziouzenkova, O.1    Plutzky, J.2
  • 92
    • 84862000905 scopus 로고    scopus 로고
    • Retinaldehyde dehydrogenase 1 regulates a thermogenic program in white adipose tissue
    • Kiefer FW, Vernochet C, O'Brien P, Spoerl S, Brown JD, Nallamshetty S, et al. Retinaldehyde dehydrogenase 1 regulates a thermogenic program in white adipose tissue. Nat Med. 2012; 18: 918-25.
    • (2012) Nat Med. , vol.18 , pp. 918-925
    • Kiefer, F.W.1    Vernochet, C.2    O'Brien, P.3    Spoerl, S.4    Brown, J.D.5    Nallamshetty, S.6
  • 93
    • 77950188754 scopus 로고    scopus 로고
    • Induction of uncoupling protein-1 in mouse embryonic fibroblast-derived adipocytes by retinoic acid
    • Mercader J, Palou A, Bonet ML. Induction of uncoupling protein-1 in mouse embryonic fibroblast-derived adipocytes by retinoic acid. Obesity (Silver Spring). 2010; 18: 655-62.
    • (2010) Obesity (Silver Spring) , vol.18 , pp. 655-662
    • Mercader, J.1    Palou, A.2    Bonet, M.L.3
  • 94
    • 14844357211 scopus 로고    scopus 로고
    • The vascular endothelial growth factor (VEGF) family: Angiogenic factors in health and disease
    • Holmes DI, Zachary I. The vascular endothelial growth factor (VEGF) family: angiogenic factors in health and disease. Genome Biol. 2005; 6: 209.
    • (2005) Genome Biol. , vol.6 , pp. 209
    • Holmes, D.I.1    Zachary, I.2
  • 95
    • 34848851922 scopus 로고    scopus 로고
    • Angiogenesis modulates adipogenesis and obesity
    • Cao Y. Angiogenesis modulates adipogenesis and obesity. J Clin Invest. 2007; 117: 2362-8.
    • (2007) J Clin Invest. , vol.117 , pp. 2362-2368
    • Cao, Y.1
  • 96
    • 77950865464 scopus 로고    scopus 로고
    • Vascular endothelial growth factor B controls endothelial fatty acid uptake
    • Hagberg CE, Falkevall A, Wang X, Larsson E, Huusko J, Nilsson I, et al. Vascular endothelial growth factor B controls endothelial fatty acid uptake. Nature. 2010; 464: 917-21.
    • (2010) Nature , vol.464 , pp. 917-921
    • Hagberg, C.E.1    Falkevall, A.2    Wang, X.3    Larsson, E.4    Huusko, J.5    Nilsson, I.6
  • 97
    • 84862740201 scopus 로고    scopus 로고
    • Resistance to obesity by repression of VEGF gene expression through induction of brown-like adipocyte differentiation
    • Lu X, Ji Y, Zhang L, Zhang Y, Zhang S, An Y, et al. Resistance to obesity by repression of VEGF gene expression through induction of brown-like adipocyte differentiation. Endocrinology. 2012; 153: 3123-32.
    • (2012) Endocrinology , vol.153 , pp. 3123-3132
    • Lu, X.1    Ji, Y.2    Zhang, L.3    Zhang, Y.4    Zhang, S.5    An, Y.6
  • 98
    • 84881186105 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is important for brown adipose tissue development and maintenance
    • Bagchi M, Kim LA, Boucher J, Walshe TE, Kahn CR, D' Amore PA. Vascular endothelial growth factor is important for brown adipose tissue development and maintenance. FASEB J. 2013; 27: 3257-71.
    • (2013) FASEB J. , vol.27 , pp. 3257-3271
    • Bagchi, M.1    Kim, L.A.2    Boucher, J.3    Walshe, T.E.4    Kahn, C.R.5    Amore P.A.D.'.6
  • 99
    • 0020688573 scopus 로고
    • Sympathetic nervous activity during exercise
    • Christensen NJ, Galbo H. Sympathetic nervous activity during exercise. Annu Rev Physiol. 1983; 45: 139-53.
    • (1983) Annu Rev Physiol. , vol.45 , pp. 139-153
    • Christensen, N.J.1    Galbo, H.2
  • 100
    • 34147128180 scopus 로고    scopus 로고
    • Association of plasma natriuretic peptide levels with metabolic risk factors in ambulatory individuals
    • Wang TJ, Larson MG, Keyes MJ, Levy D, Benjamin EJ, Vasan RS. Association of plasma natriuretic peptide levels with metabolic risk factors in ambulatory individuals. Circulation. 2007; 115: 1345-53.
    • (2007) Circulation , vol.115 , pp. 1345-1353
    • Wang, T.J.1    Larson, M.G.2    Keyes, M.J.3    Levy, D.4    Benjamin, E.J.5    Vasan, R.S.6
  • 101
    • 77957747865 scopus 로고    scopus 로고
    • Association of plasma B-type natriuretic peptide levels with obesity in a general urban Japanese population: The Suita Study
    • Sugisawa T, Kishimoto I, Kokubo Y, Makino H, Miyamoto Y, Yoshimasa Y. Association of plasma B-type natriuretic peptide levels with obesity in a general urban Japanese population: the Suita Study. Endocr J. 2010; 57: 727-33.
    • (2010) Endocr J. , vol.57 , pp. 727-733
    • Sugisawa, T.1    Kishimoto, I.2    Kokubo, Y.3    Makino, H.4    Miyamoto, Y.5    Yoshimasa, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.