The type 2 iodothyronine deiodinase is essential for adaptive thermogenesis in brown adipose tissue

Journal of Clinical Investigation

Volumn 108, Issue 9, 2001, Pages 1379-1385

  De Jesus, Lucia A ^a   Carvalho, Suzy D ^a   Ribeiro, Mirian O ^b   Schneider, Mark ^c   Kim, Sung Woo ^a   Harney, John W ^a   Larsen, P Reed ^a   Bianco, Antonio C ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 [2 [[2 (3 CHLOROPHENYL) 2 HYDROXYETHYL]AMINO]PROPYL] 1,3 BENZODIOXOLE 2,2 DICARBOXYLIC ACID; CYCLIC AMP; FORSKOLIN; IODOTHYRONINE DEIODINASE TYPE 2; LIOTHYRONINE; MESSENGER RNA; NORADRENALIN; THYROID HORMONE RECEPTOR; THYROID HORMONE RECEPTOR ALPHA; THYROID HORMONE RECEPTOR BETA; THYROXINE DEIODINASE; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 1;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BROWN ADIPOSE TISSUE; COLD STRESS; CONTROLLED STUDY; ENZYME ACTIVITY; GENE DISRUPTION; HYPOTHERMIA; HYPOTHYROIDISM; LIPOLYSIS; MITOCHONDRION; MOUSE; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BINDING; SHIVERING; SURVIVAL; SYMPATHETIC TONE; THERMOGENESIS; THERMOREGULATION; WEIGHT REDUCTION;

ADIPOSE TISSUE, BROWN; ANIMALS; BODY WEIGHT; CELLS, CULTURED; CYCLIC AMP; DIOXOLES; DOSE-RESPONSE RELATIONSHIP, DRUG; FORSKOLIN; HOMEOSTASIS; HYPOGLYCEMIC AGENTS; IODIDE PEROXIDASE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MITOCHONDRIA; MODELS, BIOLOGICAL; OXYGEN; RNA, MESSENGER; TEMPERATURE; TIME; TIME FACTORS; TRIGLYCERIDES; TRIIODOTHYRONINE; WEIGHT LOSS;

EID: 0035185505     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI200113803     Document Type: Article

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