In vivo genotoxicity of estragole in male F344 rats

Environmental and Molecular Mutagenesis

Volumn 56, Issue 4, 2015, Pages 356-365

  Ding, Wei ^a   Levy, Dan D ^b   Bishop, Michelle E ^a   Pearce, Mason G ^a   Davis, Kelly J ^a   Jeffrey, Alan M ^c   Duan, Jian Dong ^c   Williams, Gary M ^c   White, Gene A ^a   Lyn Cook, Lascelles E ^a   Manjanatha, Mugimane G ^a  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^c NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

Cell proliferation; Direct DNA damage; In vivo comet assay; Inflammation; Oxidative DNA damage

Indexed keywords

8 OXOGUANINE DNA N GLYCOSYLASE; CORN OIL; ENDONUCLEASE; ENZYME; ESTRAGOLE; SAFROLE; UNCLASSIFIED DRUG; ANISOLE DERIVATIVE; DNA ADDUCT; DNA GLYCOSYLTRANSFERASE; OXOGUANINE GLYCOSYLASE 1, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASSAY; BLOOD; CARCINOGENICITY; COMET ASSAY; CONTROLLED STUDY; DNA ADDUCT ASSAY; DNA DAMAGE; DNA STRAND BREAKAGE; DOSE RESPONSE; ENZYME THERAPY; FISCHER 344 RAT; GENOTOXICITY; HISTOPATHOLOGY; IN VIVO STUDY; KIDNEY INJURY; LIVER; LIVER INJURY; MALE; MICRONUCLEUS TEST; NEOPLASM; NONHUMAN; OXIDATIVE STRESS; RAT; STOMACH; ANIMAL; DNA ADDUCT; DRUG EFFECTS; KIDNEY; METABOLISM; MUTAGEN TESTING; PATHOLOGY; PROCEDURES;

RATTUS; RODENTIA; ZEA MAYS;

ANIMALS; ANISOLES; COMET ASSAY; DNA ADDUCTS; DNA DAMAGE; DNA GLYCOSYLASES; KIDNEY; LIVER; MALE; MICRONUCLEUS TESTS; MUTAGENICITY TESTS; RATS, INBRED F344; SAFROLE; STOMACH;

EID: 84928018261     PISSN: 08936692     EISSN: 10982280     Source Type: Journal    
DOI: 10.1002/em.21918     Document Type: Article

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