Possible involvement of genotoxic mechanisms in estragole-induced hepatocarcinogenesis in rats

Archives of Toxicology

Volumn 86, Issue 10, 2012, Pages 1593-1601

  Suzuki, Yuta ^a,b   Umemura, Takashi ^a   Hibi, Daisuke ^a,b   Inoue, Tomoki ^a   Jin, Meilan ^a   Ishii, Yuji ^a   Sakai, Hiroki ^b   Nohmi, Takehiko ^a   Yanai, Tokuma ^b   Nishikawa, Akiyoshi ^a   Ogawa, Kumiko ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b GIFU UNIVERSITY   (Japan)

Author keywords

Estragole; Genotoxicity; Hepatocarcinogenesis; Rat

Indexed keywords

CYCLINE; ESTRAGOLE; GLUTATHIONE TRANSFERASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARCINOGENICITY; CHEMICAL CARCINOGENESIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA ADDUCT; GENOTOXICITY; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; LIQUID CHROMATOGRAPHY; LIVER CARCINOGENESIS; LIVER WEIGHT; MALE; MASS SPECTROMETRY; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; RAT;

ANIMALS; ANISOLES; CHROMATOGRAPHY, LIQUID; DNA ADDUCTS; DOSE-RESPONSE RELATIONSHIP, DRUG; FLAVORING AGENTS; GLUTATHIONE S-TRANSFERASE PI; IMMUNOHISTOCHEMISTRY; LIVER NEOPLASMS; MALE; MUTAGENS; PROLIFERATING CELL NUCLEAR ANTIGEN; RATS; RATS, INBRED F344; TANDEM MASS SPECTROMETRY; TIME FACTORS;

RATTUS;

EID: 84866528090     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-012-0865-8     Document Type: Article

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